JP2025507820A5 - - Google Patents
Info
- Publication number
- JP2025507820A5 JP2025507820A5 JP2024551891A JP2024551891A JP2025507820A5 JP 2025507820 A5 JP2025507820 A5 JP 2025507820A5 JP 2024551891 A JP2024551891 A JP 2024551891A JP 2024551891 A JP2024551891 A JP 2024551891A JP 2025507820 A5 JP2025507820 A5 JP 2025507820A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- ring
- independently
- compound according
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263315968P | 2022-03-02 | 2022-03-02 | |
| US63/315,968 | 2022-03-02 | ||
| US202363478467P | 2023-01-04 | 2023-01-04 | |
| US63/478,467 | 2023-01-04 | ||
| PCT/US2023/063623 WO2023168367A1 (en) | 2022-03-02 | 2023-03-02 | QUINOLINE cGAS ANTAGONIST COMPOUNDS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025507820A JP2025507820A (ja) | 2025-03-21 |
| JP2025507820A5 true JP2025507820A5 (https=) | 2026-03-10 |
Family
ID=85781707
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024551891A Pending JP2025507820A (ja) | 2022-03-02 | 2023-03-02 | キノリンｃＧａｓアンタゴニスト化合物 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US12281078B2 (https=) |
| EP (1) | EP4486734A1 (https=) |
| JP (1) | JP2025507820A (https=) |
| KR (1) | KR20250004639A (https=) |
| CN (1) | CN119137112A (https=) |
| AU (1) | AU2023228915A1 (https=) |
| CA (1) | CA3253386A1 (https=) |
| IL (1) | IL315346A (https=) |
| MX (1) | MX2024010674A (https=) |
| TW (1) | TW202342021A (https=) |
| WO (1) | WO2023168367A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230062845A (ko) | 2020-09-03 | 2023-05-09 | 이뮨센서 테라퓨틱스, 인코포레이티드 | 퀴놀린 cgas 길항제 화합물 |
| IL315346A (en) | 2022-03-02 | 2024-11-01 | Immunesensor Therapeutics Inc | CGAS agonistic quinoline compounds |
| US20260092048A1 (en) | 2024-08-30 | 2026-04-02 | Immunesensor Therapeutics, Inc. | Solid forms and salts of a quinoline cgas antagonist compound |
| WO2026057087A1 (zh) * | 2024-09-14 | 2026-03-19 | 杭州英创医药科技有限公司 | 作为cGAS抑制剂的化合物 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3542785A (en) * | 1967-05-15 | 1970-11-24 | Ciba Geigy Corp | 2-hydroxy-4-aryl-quinolines |
| US3668207A (en) * | 1970-01-22 | 1972-06-06 | Ciba Geigy Corp | 2-amino-4-aryl-quinolines |
| BR0312204A (pt) * | 2002-06-27 | 2005-04-26 | Schering Ag | Antagonista de receptor ccr5 de quinolina substituìda |
| CA2699697A1 (en) | 2007-09-27 | 2009-04-02 | F. Hoffmann-La Roche Ag | Quinoline derivatives as 5ht5a receptor antagonists |
| US20190127354A1 (en) * | 2015-12-14 | 2019-05-02 | Fundación Para La Investigación Médica Aplicada | 2,4,6,7-tetrasubstituted quinoline compounds as inhibitors of dna methyltransferases |
| CN109111426B (zh) | 2017-06-23 | 2021-12-14 | 中国科学院上海药物研究所 | 一类稠合双环杂芳基或芳基化合物，及其用途 |
| KR20240151869A (ko) | 2017-09-08 | 2024-10-18 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | Enpp1 저해제 및 암의 치료용의 이의 용도 |
| WO2019241787A1 (en) | 2018-06-15 | 2019-12-19 | The Regents Of The University Of Colorado A Body Corporate | Novel cyclic gmp-amp synthase (cgas) inhibitors and their method of use |
| PL3829581T3 (pl) | 2018-07-27 | 2024-07-01 | Arcus Biosciences, Inc. | Antagoniści pirydonu a2r |
| EP3620164A1 (en) * | 2018-09-05 | 2020-03-11 | Genoscience Pharma SAS | Substituted 2,4 diamino-quinoline as new medicament for fibrosis, autophagy and cathepsins b (ctsb), l (ctsl) and d (ctsd) related diseases |
| CA3125626A1 (en) | 2019-01-04 | 2020-07-09 | Bellbrook Labs, Llc | Inhibitors of cgas activity as therapeutic agents |
| CA3164995A1 (en) | 2019-12-20 | 2021-06-24 | Erasca, Inc. | Tricyclic pyridones and pyrimidones |
| AU2021211437A1 (en) | 2020-01-20 | 2022-09-15 | Crescenta Biosciences | Novel cell metabolism modulating compounds and uses thereof |
| WO2022010948A1 (en) | 2020-07-06 | 2022-01-13 | Crescenta Biosciences | Novel cell metabolism modulating compounds and uses thereof for the treatment of viral diseases |
| KR20230062845A (ko) | 2020-09-03 | 2023-05-09 | 이뮨센서 테라퓨틱스, 인코포레이티드 | 퀴놀린 cgas 길항제 화합물 |
| IL315346A (en) | 2022-03-02 | 2024-11-01 | Immunesensor Therapeutics Inc | CGAS agonistic quinoline compounds |
-
2023
- 2023-03-02 IL IL315346A patent/IL315346A/en unknown
- 2023-03-02 EP EP23714185.8A patent/EP4486734A1/en active Pending
- 2023-03-02 US US18/177,732 patent/US12281078B2/en active Active
- 2023-03-02 AU AU2023228915A patent/AU2023228915A1/en active Pending
- 2023-03-02 TW TW112107684A patent/TW202342021A/zh unknown
- 2023-03-02 CN CN202380037098.5A patent/CN119137112A/zh active Pending
- 2023-03-02 CA CA3253386A patent/CA3253386A1/en active Pending
- 2023-03-02 KR KR1020247032755A patent/KR20250004639A/ko active Pending
- 2023-03-02 WO PCT/US2023/063623 patent/WO2023168367A1/en not_active Ceased
- 2023-03-02 JP JP2024551891A patent/JP2025507820A/ja active Pending
- 2023-07-17 US US18/353,718 patent/US12091387B2/en active Active
-
2024
- 2024-08-30 MX MX2024010674A patent/MX2024010674A/es unknown
-
2025
- 2025-02-27 US US19/066,046 patent/US20260042737A1/en active Pending
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