JP2025507820A5 - - Google Patents

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Publication number
JP2025507820A5
JP2025507820A5 JP2024551891A JP2024551891A JP2025507820A5 JP 2025507820 A5 JP2025507820 A5 JP 2025507820A5 JP 2024551891 A JP2024551891 A JP 2024551891A JP 2024551891 A JP2024551891 A JP 2024551891A JP 2025507820 A5 JP2025507820 A5 JP 2025507820A5
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JP
Japan
Application number
JP2024551891A
Other languages
Japanese (ja)
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JPWO2023168367A5 (https=
JP2025507820A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/063623 external-priority patent/WO2023168367A1/en
Publication of JP2025507820A publication Critical patent/JP2025507820A/ja
Publication of JPWO2023168367A5 publication Critical patent/JPWO2023168367A5/ja
Publication of JP2025507820A5 publication Critical patent/JP2025507820A5/ja
Pending legal-status Critical Current

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JP2024551891A 2022-03-02 2023-03-02 キノリンcGasアンタゴニスト化合物 Pending JP2025507820A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202263315968P 2022-03-02 2022-03-02
US63/315,968 2022-03-02
US202363478467P 2023-01-04 2023-01-04
US63/478,467 2023-01-04
PCT/US2023/063623 WO2023168367A1 (en) 2022-03-02 2023-03-02 QUINOLINE cGAS ANTAGONIST COMPOUNDS

Publications (3)

Publication Number Publication Date
JP2025507820A JP2025507820A (ja) 2025-03-21
JPWO2023168367A5 JPWO2023168367A5 (https=) 2026-03-10
JP2025507820A5 true JP2025507820A5 (https=) 2026-03-10

Family

ID=85781707

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024551891A Pending JP2025507820A (ja) 2022-03-02 2023-03-02 キノリンcGasアンタゴニスト化合物

Country Status (11)

Country Link
US (3) US12281078B2 (https=)
EP (1) EP4486734A1 (https=)
JP (1) JP2025507820A (https=)
KR (1) KR20250004639A (https=)
CN (1) CN119137112A (https=)
AU (1) AU2023228915A1 (https=)
CA (1) CA3253386A1 (https=)
IL (1) IL315346A (https=)
MX (1) MX2024010674A (https=)
TW (1) TW202342021A (https=)
WO (1) WO2023168367A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230062845A (ko) 2020-09-03 2023-05-09 이뮨센서 테라퓨틱스, 인코포레이티드 퀴놀린 cgas 길항제 화합물
CN119137112A (zh) 2022-03-02 2024-12-13 免疫传感器治疗股份有限公司 喹啉cGAS拮抗剂化合物
WO2026050765A1 (en) 2024-08-30 2026-03-05 Immunesensor Therapeutics, Inc. Solid forms and salts of a quinoline cgas antagonist compound
WO2026057087A1 (zh) * 2024-09-14 2026-03-19 杭州英创医药科技有限公司 作为cGAS抑制剂的化合物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3542785A (en) * 1967-05-15 1970-11-24 Ciba Geigy Corp 2-hydroxy-4-aryl-quinolines
US3668207A (en) * 1970-01-22 1972-06-06 Ciba Geigy Corp 2-amino-4-aryl-quinolines
WO2004002960A1 (en) * 2002-06-27 2004-01-08 Schering Aktiengesellschaft Substituted quinoline ccr5 receptor antagonists
AU2008303602A1 (en) 2007-09-27 2009-04-02 F. Hoffmann-La Roche Ag Quinoline derivatives as 5HT5A receptor antagonists
JP2019501904A (ja) * 2015-12-14 2019-01-24 ファンダシオン パラ ラ インベスティガシオン メディカ アプリカダFundacion Para La Investigasion Medica Aplicada Dnaメチルトランスフェラーゼの阻害剤としての2,4,6,7−四置換キノリン化合物
CN109111426B (zh) 2017-06-23 2021-12-14 中国科学院上海药物研究所 一类稠合双环杂芳基或芳基化合物,及其用途
IL302338B2 (en) 2017-09-08 2024-10-01 Univ Leland Stanford Junior Enpp1 inhibitors and their use for the treatment of cancer
WO2019241787A1 (en) 2018-06-15 2019-12-19 The Regents Of The University Of Colorado A Body Corporate Novel cyclic gmp-amp synthase (cgas) inhibitors and their method of use
US12064433B2 (en) 2018-07-27 2024-08-20 Arcus Biosciences, Inc. Pyridone A2R antagonists
EP3620164A1 (en) * 2018-09-05 2020-03-11 Genoscience Pharma SAS Substituted 2,4 diamino-quinoline as new medicament for fibrosis, autophagy and cathepsins b (ctsb), l (ctsl) and d (ctsd) related diseases
WO2020142735A1 (en) 2019-01-04 2020-07-09 BellBrook Labs Inhibitors of cgas activity as therapeutic agents
EP4076667A1 (en) 2019-12-20 2022-10-26 Erasca, Inc. Tricyclic pyridones and pyrimidones
CN115209883B (zh) 2020-01-20 2025-05-20 新月生物科学 新型细胞代谢调节化合物及其用途
JP2023532998A (ja) 2020-07-06 2023-08-01 クレセンタ バイオサイエンシズ 新規細胞代謝調節化合物およびそのウイルス性疾患の治療のための使用
KR20230062845A (ko) 2020-09-03 2023-05-09 이뮨센서 테라퓨틱스, 인코포레이티드 퀴놀린 cgas 길항제 화합물
CN119137112A (zh) 2022-03-02 2024-12-13 免疫传感器治疗股份有限公司 喹啉cGAS拮抗剂化合物

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