JPWO2023154309A5 - - Google Patents
Info
- Publication number
- JPWO2023154309A5 JPWO2023154309A5 JP2024546422A JP2024546422A JPWO2023154309A5 JP WO2023154309 A5 JPWO2023154309 A5 JP WO2023154309A5 JP 2024546422 A JP2024546422 A JP 2024546422A JP 2024546422 A JP2024546422 A JP 2024546422A JP WO2023154309 A5 JPWO2023154309 A5 JP WO2023154309A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- optionally substituted
- independently selected
- halogen
- groups
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263307876P | 2022-02-08 | 2022-02-08 | |
| US63/307,876 | 2022-02-08 | ||
| PCT/US2023/012578 WO2023154309A1 (en) | 2022-02-08 | 2023-02-08 | 4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran] derivatives as inhibitors of apol1 and methods of using same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2025505644A JP2025505644A (ja) | 2025-02-28 |
| JP2025505644A5 JP2025505644A5 (https=) | 2026-02-04 |
| JPWO2023154309A5 true JPWO2023154309A5 (https=) | 2026-02-04 |
Family
ID=85685675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024546422A Pending JP2025505644A (ja) | 2022-02-08 | 2023-02-08 | Ａｐｏｌ１の阻害剤としての４’，５’－ジヒドロスピロ［ピペリジン－４，７’－チエノ［２，３－ｃ］ピラン］誘導体、及びそれを使用する方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20250136612A1 (https=) |
| EP (1) | EP4476228A1 (https=) |
| JP (1) | JP2025505644A (https=) |
| CN (1) | CN119013281A (https=) |
| AU (1) | AU2023218939A1 (https=) |
| CA (1) | CA3251124A1 (https=) |
| WO (1) | WO2023154309A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI848031B (zh) | 2018-12-17 | 2024-07-11 | 美商維泰克斯製藥公司 | Apol1抑制劑及其使用方法 |
| WO2021154997A1 (en) | 2020-01-29 | 2021-08-05 | Vertex Pharmaceuticals Incorporated | Inhibitors of apol1 and methods of using same |
| CA3185604A1 (en) | 2020-06-12 | 2021-12-16 | Vertex Pharmaceuticals Incorporated | Inhibitors of apol1 and use of the same |
| WO2021252863A1 (en) | 2020-06-12 | 2021-12-16 | Vertex Pharmaceuticals Incorporated | Solid forms of apol1 inhibitor and using the same |
| IL300298B2 (en) | 2020-08-26 | 2025-06-01 | Vertex Pharma | Inhibitors of apol1 and methods of using same |
| IL314330A (en) | 2022-01-18 | 2024-09-01 | Maze Therapeutics Inc | Apol1 inhibitors and methods of use |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2020414A1 (en) * | 2007-06-20 | 2009-02-04 | Laboratorios del Dr. Esteve S.A. | spiro[piperidine-4,4'-thieno[3,2-c]pyran] derivatives and related compounds as inhibitors of the sigma receptor for the treatment of psychosis |
| WO2021220178A1 (en) * | 2020-04-29 | 2021-11-04 | Cominnex Zrt. | Iap antagonists and their therapeutic applications |
| WO2021252849A1 (en) * | 2020-06-12 | 2021-12-16 | Vertex Pharmaceuticals Incorporated | Inhibitors of apol1 and use of the same |
-
2023
- 2023-02-08 EP EP23711582.9A patent/EP4476228A1/en active Pending
- 2023-02-08 AU AU2023218939A patent/AU2023218939A1/en active Pending
- 2023-02-08 JP JP2024546422A patent/JP2025505644A/ja active Pending
- 2023-02-08 WO PCT/US2023/012578 patent/WO2023154309A1/en not_active Ceased
- 2023-02-08 US US18/836,407 patent/US20250136612A1/en active Pending
- 2023-02-08 CN CN202380032015.3A patent/CN119013281A/zh active Pending
- 2023-02-08 CA CA3251124A patent/CA3251124A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2024050527A5 (https=) | ||
| RU2012116877A (ru) | Соединения 2-пиридона, применяемые в качестве ингибиторов нейтрофильной эластазы | |
| JP2007517035A5 (https=) | ||
| JP2024001048A5 (https=) | ||
| JPWO2022216971A5 (https=) | ||
| JP2019518046A5 (https=) | ||
| RU2014131065A (ru) | Димерные соединения-агонисты рецептора fgf ( fgfr ), способ их получения и их терапевтическое применение | |
| RU2003104821A (ru) | Новые производные фенилаланина | |
| JP2007502288A5 (https=) | ||
| RU2011113402A (ru) | ПИРИДО[5,4d]ПИРИМИДИНЫ В КАЧЕСТВЕ ИНГИБИТОРОВ ПРОЛИФЕРАЦИИ КЛЕТОК | |
| JPWO2023099592A5 (https=) | ||
| JP2020502047A5 (https=) | ||
| JP2013542267A5 (https=) | ||
| RU2008107733A (ru) | Ингибиторы gsk-3 | |
| RU2007101653A (ru) | Производные 1-азабицикло[3.3.1]нонанов | |
| RU2008119692A (ru) | Новые 1-азабициклоалкилпроизводные для лечения психических растройств | |
| JPWO2021030556A5 (https=) | ||
| JP2021524487A5 (https=) | ||
| JP2021524482A5 (https=) | ||
| JPWO2021030555A5 (https=) | ||
| JP2019527724A5 (https=) | ||
| JP2020111571A5 (https=) | ||
| JOP20240217A1 (ar) | مشتقات الكوينولين كمُعدِّلات للعضو x2 لمستقبل بروتين g مرتبط بـ mas ومنتجات ذات صلة | |
| JP2018536678A5 (https=) | ||
| JPWO2023154309A5 (https=) |