JPWO2023132338A5 - - Google Patents
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- Publication number
- JPWO2023132338A5 JPWO2023132338A5 JP2023572478A JP2023572478A JPWO2023132338A5 JP WO2023132338 A5 JPWO2023132338 A5 JP WO2023132338A5 JP 2023572478 A JP2023572478 A JP 2023572478A JP 2023572478 A JP2023572478 A JP 2023572478A JP WO2023132338 A5 JPWO2023132338 A5 JP WO2023132338A5
- Authority
- JP
- Japan
- Prior art keywords
- mass spectrometry
- protein
- sugar
- amino acid
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 15
- 238000004949 mass spectrometry Methods 0.000 claims 11
- -1 methylene compound Chemical class 0.000 claims 8
- 102000004169 proteins and genes Human genes 0.000 claims 8
- 108090000623 proteins and genes Proteins 0.000 claims 8
- 238000012986 modification Methods 0.000 claims 7
- 238000006467 substitution reaction Methods 0.000 claims 7
- 230000004048 modification Effects 0.000 claims 6
- 150000001413 amino acids Chemical class 0.000 claims 5
- 238000006845 Michael addition reaction Methods 0.000 claims 4
- 238000006243 chemical reaction Methods 0.000 claims 3
- 238000013467 fragmentation Methods 0.000 claims 3
- 238000006062 fragmentation reaction Methods 0.000 claims 3
- 241001634120 Adeno-associated virus - 5 Species 0.000 claims 2
- 241000700605 Viruses Species 0.000 claims 2
- 125000000539 amino acid group Chemical group 0.000 claims 2
- 125000004122 cyclic group Chemical group 0.000 claims 2
- 241000702421 Dependoparvovirus Species 0.000 claims 1
- OVRNDRQMDRJTHS-UHFFFAOYSA-N N-acelyl-D-glucosamine Natural products CC(=O)NC1C(O)OC(CO)C(O)C1O OVRNDRQMDRJTHS-UHFFFAOYSA-N 0.000 claims 1
- OVRNDRQMDRJTHS-FMDGEEDCSA-N N-acetyl-beta-D-glucosamine Chemical group CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O OVRNDRQMDRJTHS-FMDGEEDCSA-N 0.000 claims 1
- MBLBDJOUHNCFQT-LXGUWJNJSA-N N-acetylglucosamine Natural products CC(=O)N[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)CO MBLBDJOUHNCFQT-LXGUWJNJSA-N 0.000 claims 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 claims 1
- 239000004473 Threonine Substances 0.000 claims 1
- 238000004458 analytical method Methods 0.000 claims 1
- 238000007068 beta-elimination reaction Methods 0.000 claims 1
- 210000000234 capsid Anatomy 0.000 claims 1
- MJKVTPMWOKAVMS-UHFFFAOYSA-N hydroxy-coumarin Natural products C1=CC=C2OC(=O)C(O)=CC2=C1 MJKVTPMWOKAVMS-UHFFFAOYSA-N 0.000 claims 1
- 229950006780 n-acetylglucosamine Drugs 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022001248 | 2022-01-06 | ||
| PCT/JP2023/000038 WO2023132338A1 (ja) | 2022-01-06 | 2023-01-05 | タンパク質における糖が結合したアミノ酸部位を同定する方法、及びキット |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2023132338A1 JPWO2023132338A1 (https=) | 2023-07-13 |
| JPWO2023132338A5 true JPWO2023132338A5 (https=) | 2024-09-18 |
Family
ID=87073749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023572478A Pending JPWO2023132338A1 (https=) | 2022-01-06 | 2023-01-05 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20240361332A1 (https=) |
| EP (1) | EP4462114A4 (https=) |
| JP (1) | JPWO2023132338A1 (https=) |
| CN (1) | CN118541607A (https=) |
| WO (1) | WO2023132338A1 (https=) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20161787T1 (hr) * | 2011-02-16 | 2017-02-24 | Cellseed Inc. | Sredstvo za označavanje za post-translacijsku modifikacijsku analizu serina i treonina |
| NZ791267A (en) * | 2016-08-15 | 2025-11-28 | Genzyme Corp | Methods for detecting AAV |
| JP2019052995A (ja) | 2017-09-19 | 2019-04-04 | 住友ベークライト株式会社 | 糖タンパク質における糖鎖の結合領域の同定方法およびキット |
-
2023
- 2023-01-05 JP JP2023572478A patent/JPWO2023132338A1/ja active Pending
- 2023-01-05 EP EP23737289.1A patent/EP4462114A4/en active Pending
- 2023-01-05 WO PCT/JP2023/000038 patent/WO2023132338A1/ja not_active Ceased
- 2023-01-05 CN CN202380016364.6A patent/CN118541607A/zh active Pending
-
2024
- 2024-07-05 US US18/764,888 patent/US20240361332A1/en active Pending
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