JPWO2023076902A5 - - Google Patents

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Publication number
JPWO2023076902A5
JPWO2023076902A5 JP2024524728A JP2024524728A JPWO2023076902A5 JP WO2023076902 A5 JPWO2023076902 A5 JP WO2023076902A5 JP 2024524728 A JP2024524728 A JP 2024524728A JP 2024524728 A JP2024524728 A JP 2024524728A JP WO2023076902 A5 JPWO2023076902 A5 JP WO2023076902A5
Authority
JP
Japan
Prior art keywords
lipid
lipid nanoparticles
mol
poegma
dlin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024524728A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024541924A5 (https=
JP2024541924A (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/078659 external-priority patent/WO2023076902A1/en
Publication of JP2024541924A publication Critical patent/JP2024541924A/ja
Publication of JP2024541924A5 publication Critical patent/JP2024541924A5/ja
Publication of JPWO2023076902A5 publication Critical patent/JPWO2023076902A5/ja
Pending legal-status Critical Current

Links

JP2024524728A 2021-10-25 2022-10-25 Poegmaベース脂質ナノ粒子 Pending JP2024541924A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163271595P 2021-10-25 2021-10-25
US63/271,595 2021-10-25
PCT/US2022/078659 WO2023076902A1 (en) 2021-10-25 2022-10-25 Poegma-based lipid nanoparticles

Publications (3)

Publication Number Publication Date
JP2024541924A JP2024541924A (ja) 2024-11-13
JP2024541924A5 JP2024541924A5 (https=) 2025-10-31
JPWO2023076902A5 true JPWO2023076902A5 (https=) 2025-10-31

Family

ID=86158533

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024524728A Pending JP2024541924A (ja) 2021-10-25 2022-10-25 Poegmaベース脂質ナノ粒子

Country Status (6)

Country Link
US (1) US20250049729A1 (https=)
EP (1) EP4422605A4 (https=)
JP (1) JP2024541924A (https=)
CN (1) CN118201605A (https=)
CA (1) CA3236153A1 (https=)
WO (1) WO2023076902A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117562869B (zh) * 2023-05-05 2024-07-16 中南大学湘雅医院 一种治疗关节疼痛的氢氧化镁纳米粒、其制备方法及应用
WO2025067389A1 (en) * 2023-09-28 2025-04-03 Immorna (hangzhou) Biotechnology Co., Ltd. Lipid complex nanoparticle for lung-targeted delivery of nucleic acid therapeutic agent
WO2025081189A1 (en) * 2023-10-12 2025-04-17 Georgia Tech Research Corporation Methods and compositions for lipid nanoparticle (lnp) mediated delivery of mrna encoded synthetic antigens for universal tumor targeting by car t cells
CN118001253A (zh) * 2024-02-07 2024-05-10 北京大学 一种肾脏靶向mRNA-LNP递送技术和疾病治疗方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7799565B2 (en) * 2004-06-07 2010-09-21 Protiva Biotherapeutics, Inc. Lipid encapsulated interfering RNA
US8497356B2 (en) 2009-02-17 2013-07-30 Duke University Biomolecule polymer conjugates and methods for making the same
US10364451B2 (en) 2013-05-30 2019-07-30 Duke University Polymer conjugates having reduced antigenicity and methods of using the same
US11752213B2 (en) 2015-12-21 2023-09-12 Duke University Surfaces having reduced non-specific binding and antigenicity
WO2017112825A2 (en) 2015-12-21 2017-06-29 Duke University Polymer conjugates having reduced antigenicity and methods of using the same
WO2020051220A1 (en) 2018-09-04 2020-03-12 The Board of the Regents of the University of Texas System Compositions and methods for organ specific delivery of nucleic acids
CN112996519B (zh) * 2018-09-04 2025-02-28 德克萨斯大学系统董事会 用于核酸的器官特异性递送的组合物和方法
AU2021232069A1 (en) * 2020-03-05 2022-11-03 Flagship Pioneering Innovations Vi, Llc Host defense suppressing methods and compositions for modulating a genome
MX2023000806A (es) * 2020-07-17 2023-04-11 Generation Bio Co Métodos para encapsular polinucleótidos en tamaños reducidos de nanopartículas lipídicas y formulación novedosa de estos.
CN112961065B (zh) * 2021-02-05 2023-03-14 嘉晨西海(杭州)生物技术有限公司 一种可电离脂质分子及其制备方法及其在制备脂质纳米颗粒的应用
WO2022212911A1 (en) 2021-04-01 2022-10-06 Duke University Poegma copolymer conjugates and methods of treating diseases

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