JPWO2023051802A5 - - Google Patents

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Publication number
JPWO2023051802A5
JPWO2023051802A5 JP2024519557A JP2024519557A JPWO2023051802A5 JP WO2023051802 A5 JPWO2023051802 A5 JP WO2023051802A5 JP 2024519557 A JP2024519557 A JP 2024519557A JP 2024519557 A JP2024519557 A JP 2024519557A JP WO2023051802 A5 JPWO2023051802 A5 JP WO2023051802A5
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JP
Japan
Prior art keywords
rest
cells
neurons
variant
glial cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024519557A
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English (en)
Japanese (ja)
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JP2024534667A (ja
JP2024534667A5 (https=
Publication date
Priority claimed from CN202111158620.4A external-priority patent/CN115887655B/zh
Application filed filed Critical
Publication of JP2024534667A publication Critical patent/JP2024534667A/ja
Publication of JP2024534667A5 publication Critical patent/JP2024534667A5/ja
Publication of JPWO2023051802A5 publication Critical patent/JPWO2023051802A5/ja
Pending legal-status Critical Current

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JP2024519557A 2021-09-30 2022-09-30 神経系疾患の直接分化転換治療 Pending JP2024534667A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN202111158620.4A CN115887655B (zh) 2021-09-30 2021-09-30 直接转分化治疗神经系统疾病
CN202111158620.4 2021-09-30
PCT/CN2022/123409 WO2023051802A1 (zh) 2021-09-30 2022-09-30 直接转分化治疗神经系统疾病

Publications (3)

Publication Number Publication Date
JP2024534667A JP2024534667A (ja) 2024-09-20
JP2024534667A5 JP2024534667A5 (https=) 2025-10-08
JPWO2023051802A5 true JPWO2023051802A5 (https=) 2025-10-08

Family

ID=85750328

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024519557A Pending JP2024534667A (ja) 2021-09-30 2022-09-30 神経系疾患の直接分化転換治療

Country Status (8)

Country Link
US (1) US20250115650A1 (https=)
EP (1) EP4410296A4 (https=)
JP (1) JP2024534667A (https=)
KR (1) KR20240082366A (https=)
CN (3) CN120754249A (https=)
AU (1) AU2022357103A1 (https=)
CA (1) CA3233534A1 (https=)
WO (1) WO2023051802A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4692360A1 (en) * 2023-03-30 2026-02-11 Shanghai Genemagic Biosciences Co., Ltd. Expression vector and composition for treating nervous system diseases
WO2025173411A1 (ja) * 2024-02-14 2025-08-21 国立大学法人筑波大学 網膜神経節細胞分化誘導用キット、医薬組成物及び緑内障モデル

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2774698B1 (fr) * 1998-02-12 2002-03-01 Rhone Poulenc Rorer Sa Utilisation d'elements de regulation negative pour l'expression neurospecifique de transgenes
ITVA20060041A1 (it) * 2006-07-05 2008-01-06 Dialectica Srl Uso di composti derivati amminotiazolici, di loro composizioni farmaceutiche, nel trattamento di malattie caratterizzate dalla anormale repressione della trascrizione genica, particolarmente il morbo di huntington
WO2009058014A2 (en) * 2007-11-02 2009-05-07 Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patientenzorg Polypeptides involved in neuronal regeneration-associated gene expression
JP5850321B2 (ja) * 2010-02-10 2016-02-03 公立大学法人横浜市立大学 神経選択的転写抑制因子NRSFに特異的に結合するmSin3Bに結合する化合物の利用
WO2014071157A1 (en) * 2012-11-01 2014-05-08 The Regents Of The University Of California Methods for engineering non-neuronal cells into neurons and using newly engineered neurons to treat neurodegenerative diseases
WO2016019315A2 (en) * 2014-08-01 2016-02-04 Oregon Health & Science University Methods and compositions useful in manipulating the stability of re1 silencing transcription factor
WO2018206798A1 (en) * 2017-05-12 2018-11-15 Parmar Malin Systems
CA3096691A1 (en) * 2018-04-11 2019-10-17 The Regents Of The University Of California Reprogramming of non-neuronal cells into neurons and methods and compositions to treat neurodegenerative diseases and disorders
CN112566640A (zh) * 2018-06-18 2021-03-26 罗切斯特大学 治疗精神分裂症和其他神经精神病症的方法
JP7699588B2 (ja) * 2019-11-22 2025-06-27 アルカメナ・ステム・セル・セラピューティクス、エルエルシー Re1サイレンシング転写因子標的遺伝子を抑制解除する組成物

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