AU2022357103A1 - Direct transdifferentiation for treatment of neurological disease - Google Patents

Direct transdifferentiation for treatment of neurological disease Download PDF

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Publication number
AU2022357103A1
AU2022357103A1 AU2022357103A AU2022357103A AU2022357103A1 AU 2022357103 A1 AU2022357103 A1 AU 2022357103A1 AU 2022357103 A AU2022357103 A AU 2022357103A AU 2022357103 A AU2022357103 A AU 2022357103A AU 2022357103 A1 AU2022357103 A1 AU 2022357103A1
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rest
cells
gfap
protein
neurons
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Xinde Hu
Jinlin SU
Haibo Zhou
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Shanghai Genemagic Biosciences Co Ltd
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Shanghai Genemagic Biosciences Co Ltd
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    • A61K48/0058Nucleic acids adapted for tissue specific expression, e.g. having tissue specific promoters as part of a contruct
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AU2022357103A 2021-09-30 2022-09-30 Direct transdifferentiation for treatment of neurological disease Pending AU2022357103A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN202111158620.4A CN115887655B (zh) 2021-09-30 2021-09-30 直接转分化治疗神经系统疾病
CN202111158620.4 2021-09-30
PCT/CN2022/123409 WO2023051802A1 (zh) 2021-09-30 2022-09-30 直接转分化治疗神经系统疾病

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AU2022357103A1 true AU2022357103A1 (en) 2024-05-02

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US (1) US20250115650A1 (https=)
EP (1) EP4410296A4 (https=)
JP (1) JP2024534667A (https=)
KR (1) KR20240082366A (https=)
CN (3) CN120754249A (https=)
AU (1) AU2022357103A1 (https=)
CA (1) CA3233534A1 (https=)
WO (1) WO2023051802A1 (https=)

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EP4692360A1 (en) * 2023-03-30 2026-02-11 Shanghai Genemagic Biosciences Co., Ltd. Expression vector and composition for treating nervous system diseases
WO2025173411A1 (ja) * 2024-02-14 2025-08-21 国立大学法人筑波大学 網膜神経節細胞分化誘導用キット、医薬組成物及び緑内障モデル

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FR2774698B1 (fr) * 1998-02-12 2002-03-01 Rhone Poulenc Rorer Sa Utilisation d'elements de regulation negative pour l'expression neurospecifique de transgenes
ITVA20060041A1 (it) * 2006-07-05 2008-01-06 Dialectica Srl Uso di composti derivati amminotiazolici, di loro composizioni farmaceutiche, nel trattamento di malattie caratterizzate dalla anormale repressione della trascrizione genica, particolarmente il morbo di huntington
WO2009058014A2 (en) * 2007-11-02 2009-05-07 Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patientenzorg Polypeptides involved in neuronal regeneration-associated gene expression
JP5850321B2 (ja) * 2010-02-10 2016-02-03 公立大学法人横浜市立大学 神経選択的転写抑制因子NRSFに特異的に結合するmSin3Bに結合する化合物の利用
WO2014071157A1 (en) * 2012-11-01 2014-05-08 The Regents Of The University Of California Methods for engineering non-neuronal cells into neurons and using newly engineered neurons to treat neurodegenerative diseases
WO2016019315A2 (en) * 2014-08-01 2016-02-04 Oregon Health & Science University Methods and compositions useful in manipulating the stability of re1 silencing transcription factor
WO2018206798A1 (en) * 2017-05-12 2018-11-15 Parmar Malin Systems
CA3096691A1 (en) * 2018-04-11 2019-10-17 The Regents Of The University Of California Reprogramming of non-neuronal cells into neurons and methods and compositions to treat neurodegenerative diseases and disorders
CN112566640A (zh) * 2018-06-18 2021-03-26 罗切斯特大学 治疗精神分裂症和其他神经精神病症的方法
JP7699588B2 (ja) * 2019-11-22 2025-06-27 アルカメナ・ステム・セル・セラピューティクス、エルエルシー Re1サイレンシング転写因子標的遺伝子を抑制解除する組成物

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CN120754249A (zh) 2025-10-10
EP4410296A1 (en) 2024-08-07
JP2024534667A (ja) 2024-09-20
CN118201623A (zh) 2024-06-14
WO2023051802A1 (zh) 2023-04-06
CN115887655B (zh) 2025-06-17
KR20240082366A (ko) 2024-06-10
CA3233534A1 (en) 2023-04-06
EP4410296A4 (en) 2025-10-15
CN115887655A (zh) 2023-04-04
US20250115650A1 (en) 2025-04-10

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