JPWO2023048291A1 - - Google Patents
Info
- Publication number
- JPWO2023048291A1 JPWO2023048291A1 JP2023549778A JP2023549778A JPWO2023048291A1 JP WO2023048291 A1 JPWO2023048291 A1 JP WO2023048291A1 JP 2023549778 A JP2023549778 A JP 2023549778A JP 2023549778 A JP2023549778 A JP 2023549778A JP WO2023048291 A1 JPWO2023048291 A1 JP WO2023048291A1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1044—Preparation or screening of libraries displayed on scaffold proteins
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1062—Isolating an individual clone by screening libraries mRNA-Display, e.g. polypeptide and encoding template are connected covalently
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1096—Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/10—Applications; Uses in screening processes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2330/00—Production
- C12N2330/30—Production chemically synthesised
- C12N2330/31—Libraries, arrays
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021156183 | 2021-09-24 | ||
| PCT/JP2022/035791 WO2023048291A1 (ja) | 2021-09-24 | 2022-09-26 | ｔＲＮＡ、アミノアシルｔＲＮＡ、ポリペプチド合成用試薬、非天然アミノ酸の導入方法、ポリペプチドの作製方法、核酸ディスプレイライブラリの作製方法、核酸－ポリペプチド連結体及びスクリーニング方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2023048291A1 true JPWO2023048291A1 (https=) | 2023-03-30 |
| JPWO2023048291A5 JPWO2023048291A5 (https=) | 2024-06-13 |
Family
ID=85720849
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023549778A Pending JPWO2023048291A1 (https=) | 2021-09-24 | 2022-09-26 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20240229015A1 (https=) |
| EP (1) | EP4389890A4 (https=) |
| JP (1) | JPWO2023048291A1 (https=) |
| CN (1) | CN118019845A (https=) |
| WO (1) | WO2023048291A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024214800A1 (ja) * | 2023-04-11 | 2024-10-17 | 富士フイルム株式会社 | 生理活性評価用のポリペプチド溶液を調製する方法、及びポリペプチドの生理活性を評価する方法 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007055429A1 (ja) * | 2005-11-14 | 2007-05-18 | Japan Science And Technology Agency | 非天然アミノ酸をタンパク質に導入するためのtRNA変異体 |
| JP2008193911A (ja) * | 2007-02-08 | 2008-08-28 | Protein Express:Kk | タンパク質のｎ末端を特異的に修飾する方法 |
| JP2012058092A (ja) * | 2010-09-09 | 2012-03-22 | Univ Of Tokyo | Ｎ−メチルアミノ酸およびその他の特殊アミノ酸を含む特殊ペプチド化合物ライブラリーの翻訳構築と活性種探索法 |
| WO2021026506A2 (en) * | 2019-08-08 | 2021-02-11 | Brickbio, Inc. | Aminoacyl-trna synthetases and cell lines for site-specific incorporation of unnatural amino acids |
| JP2021508234A (ja) * | 2017-11-02 | 2021-03-04 | ユニバーシティー オブ アイオワ リサーチ ファウンデーション | ＡＣＥ−ｔＲＮＡを用いた遺伝的再帰属を介して終止コドンレスキューする方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003281613A1 (en) | 2002-07-18 | 2004-02-09 | Takahiro Hohsaka | NON-NATURAL LABELED AMINO ACID AND METHOD OF CONSTRUCTING AMINO ACID/tRNA COMPLEX |
| RU2731211C1 (ru) | 2017-03-21 | 2020-08-31 | Фуджифилм Корпорэйшн | Пептидное соединение и способ его получения, композиция для скринингового использования и способ отбора пептидного соединения |
| JP7211389B2 (ja) | 2020-03-25 | 2023-01-24 | トヨタ自動車株式会社 | 内燃機関の制御装置 |
-
2022
- 2022-09-26 WO PCT/JP2022/035791 patent/WO2023048291A1/ja not_active Ceased
- 2022-09-26 JP JP2023549778A patent/JPWO2023048291A1/ja active Pending
- 2022-09-26 EP EP22873042.0A patent/EP4389890A4/en active Pending
- 2022-09-26 CN CN202280063245.1A patent/CN118019845A/zh active Pending
-
2024
- 2024-03-21 US US18/611,981 patent/US20240229015A1/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007055429A1 (ja) * | 2005-11-14 | 2007-05-18 | Japan Science And Technology Agency | 非天然アミノ酸をタンパク質に導入するためのtRNA変異体 |
| JP2008193911A (ja) * | 2007-02-08 | 2008-08-28 | Protein Express:Kk | タンパク質のｎ末端を特異的に修飾する方法 |
| JP2012058092A (ja) * | 2010-09-09 | 2012-03-22 | Univ Of Tokyo | Ｎ−メチルアミノ酸およびその他の特殊アミノ酸を含む特殊ペプチド化合物ライブラリーの翻訳構築と活性種探索法 |
| JP2021508234A (ja) * | 2017-11-02 | 2021-03-04 | ユニバーシティー オブ アイオワ リサーチ ファウンデーション | ＡＣＥ−ｔＲＮＡを用いた遺伝的再帰属を介して終止コドンレスキューする方法 |
| WO2021026506A2 (en) * | 2019-08-08 | 2021-02-11 | Brickbio, Inc. | Aminoacyl-trna synthetases and cell lines for site-specific incorporation of unnatural amino acids |
Non-Patent Citations (1)
| Title |
|---|
| SIMONEAU, P. ET AL.: "Codon reading scheme in Mycoplasma pneumoniae revealed by the analysis of the complete set of tRNA g", NUCLEIC ACIDS RES., vol. 21, JPN6022050607, 1993, pages 4967 - 4974, ISSN: 0005813089 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP4389890A1 (en) | 2024-06-26 |
| WO2023048291A1 (ja) | 2023-03-30 |
| US20240229015A1 (en) | 2024-07-11 |
| EP4389890A4 (en) | 2025-12-31 |
| CN118019845A (zh) | 2024-05-10 |
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