JPWO2023038088A1 - - Google Patents
Info
- Publication number
- JPWO2023038088A1 JPWO2023038088A1 JP2023546987A JP2023546987A JPWO2023038088A1 JP WO2023038088 A1 JPWO2023038088 A1 JP WO2023038088A1 JP 2023546987 A JP2023546987 A JP 2023546987A JP 2023546987 A JP2023546987 A JP 2023546987A JP WO2023038088 A1 JPWO2023038088 A1 JP WO2023038088A1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
- A61K38/063—Glutathione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D341/00—Heterocyclic compounds containing rings having three or more sulfur atoms as the only ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021146753 | 2021-09-09 | ||
| JP2021146753 | 2021-09-09 | ||
| PCT/JP2022/033764 WO2023038088A1 (ja) | 2021-09-09 | 2022-09-08 | トリスルフィド化合物を用いる、肝細胞増殖因子中のチロシン残基のニトロ化を防止する方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2023038088A1 true JPWO2023038088A1 (https=) | 2023-03-16 |
| JP7659282B2 JP7659282B2 (ja) | 2025-04-09 |
Family
ID=85506410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023546987A Active JP7659282B2 (ja) | 2021-09-09 | 2022-09-08 | トリスルフィド化合物を用いる、肝細胞増殖因子中のチロシン残基のニトロ化を防止する方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240374561A1 (https=) |
| EP (1) | EP4400103A4 (https=) |
| JP (1) | JP7659282B2 (https=) |
| CN (1) | CN117915911A (https=) |
| TW (1) | TW202321270A (https=) |
| WO (1) | WO2023038088A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4647072A1 (en) * | 2023-03-07 | 2025-11-12 | Kyowa Hakko Bio Co., Ltd. | Enhancer of physiological activity of hepatocyte growth factor |
| WO2025028521A1 (ja) | 2023-08-01 | 2025-02-06 | キリンホールディングス株式会社 | 肝機能障害の予防又は改善用組成物 |
| CN118515869A (zh) * | 2024-05-11 | 2024-08-20 | 四川大学 | 一种多硫化物聚合物、其制备方法及应用 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002087983A (ja) * | 2000-09-14 | 2002-03-27 | Toshiichi Nakamura | 筋萎縮性側索硬化症治療剤 |
| WO2018117186A1 (ja) * | 2016-12-20 | 2018-06-28 | 協和発酵バイオ株式会社 | グルタチオントリスルフィド・2水和物の結晶及びその製造方法 |
| CN113354615A (zh) * | 2020-03-02 | 2021-09-07 | 亚宝药业集团股份有限公司 | 一种α-硫辛酸杂质A的光化学制备方法 |
| WO2021231476A1 (en) * | 2020-05-12 | 2021-11-18 | The General Hospital Corporation | Glutathione trisulfide (gsssg) in neuroprotection |
| WO2022045212A1 (ja) * | 2020-08-27 | 2022-03-03 | 協和ファーマケミカル株式会社 | トリスルフィド化合物及びその包接体 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018091689A1 (en) * | 2016-11-17 | 2018-05-24 | Cytoo | Skeletal muscle hypertrophy inducers |
| JP2022074166A (ja) * | 2019-01-30 | 2022-05-18 | 協和発酵バイオ株式会社 | ポリスルフィド化合物を含有する組成物 |
| EP4342464A4 (en) * | 2021-07-08 | 2025-06-04 | Kyowa Pharma Chemical Co., Ltd. | PROPHYLACTIC OR THERAPEUTIC MEDICINE FOR PARKINSON'S DISEASE |
-
2022
- 2022-09-08 TW TW111134055A patent/TW202321270A/zh unknown
- 2022-09-08 US US18/689,734 patent/US20240374561A1/en active Pending
- 2022-09-08 EP EP22867409.9A patent/EP4400103A4/en active Pending
- 2022-09-08 CN CN202280060120.3A patent/CN117915911A/zh active Pending
- 2022-09-08 WO PCT/JP2022/033764 patent/WO2023038088A1/ja not_active Ceased
- 2022-09-08 JP JP2023546987A patent/JP7659282B2/ja active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002087983A (ja) * | 2000-09-14 | 2002-03-27 | Toshiichi Nakamura | 筋萎縮性側索硬化症治療剤 |
| WO2018117186A1 (ja) * | 2016-12-20 | 2018-06-28 | 協和発酵バイオ株式会社 | グルタチオントリスルフィド・2水和物の結晶及びその製造方法 |
| CN113354615A (zh) * | 2020-03-02 | 2021-09-07 | 亚宝药业集团股份有限公司 | 一种α-硫辛酸杂质A的光化学制备方法 |
| WO2021231476A1 (en) * | 2020-05-12 | 2021-11-18 | The General Hospital Corporation | Glutathione trisulfide (gsssg) in neuroprotection |
| WO2022045212A1 (ja) * | 2020-08-27 | 2022-03-03 | 協和ファーマケミカル株式会社 | トリスルフィド化合物及びその包接体 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN117915911A (zh) | 2024-04-19 |
| WO2023038088A1 (ja) | 2023-03-16 |
| EP4400103A4 (en) | 2025-08-20 |
| JP7659282B2 (ja) | 2025-04-09 |
| US20240374561A1 (en) | 2024-11-14 |
| EP4400103A1 (en) | 2024-07-17 |
| TW202321270A (zh) | 2023-06-01 |
Similar Documents
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20240228 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20240311 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20250311 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20250319 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 7659282 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |