JPWO2023010073A5 - - Google Patents
Info
- Publication number
- JPWO2023010073A5 JPWO2023010073A5 JP2024505066A JP2024505066A JPWO2023010073A5 JP WO2023010073 A5 JPWO2023010073 A5 JP WO2023010073A5 JP 2024505066 A JP2024505066 A JP 2024505066A JP 2024505066 A JP2024505066 A JP 2024505066A JP WO2023010073 A5 JPWO2023010073 A5 JP WO2023010073A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- cell
- engineered
- receptor
- gene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163226559P | 2021-07-28 | 2021-07-28 | |
| US63/226,559 | 2021-07-28 | ||
| PCT/US2022/074251 WO2023010073A1 (en) | 2021-07-28 | 2022-07-28 | Compositions and methods for improving t cell persistence and function |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024527997A JP2024527997A (ja) | 2024-07-26 |
| JPWO2023010073A5 true JPWO2023010073A5 (https=) | 2025-08-04 |
| JP2024527997A5 JP2024527997A5 (https=) | 2025-08-04 |
Family
ID=85087331
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024505066A Pending JP2024527997A (ja) | 2021-07-28 | 2022-07-28 | Ｔ細胞持続性及び機能を改善するための組成物及び方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20240327826A1 (https=) |
| EP (1) | EP4376858A4 (https=) |
| JP (1) | JP2024527997A (https=) |
| CN (1) | CN117813102A (https=) |
| WO (1) | WO2023010073A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024173916A1 (en) * | 2023-02-17 | 2024-08-22 | Dana-Farber Cancer Institute, Inc. | Compositions and methods of preventing t cell exhaustion |
| WO2025185585A1 (zh) * | 2024-03-05 | 2025-09-12 | 上海沙砾生物科技有限公司 | 一种鉴定靶标的方法及其应用 |
| CN118345080B (zh) * | 2024-06-17 | 2024-09-24 | 江苏柯菲平医药股份有限公司 | 一种抗耗竭t细胞及其制备方法、应用 |
| CN119120385B (zh) * | 2024-11-14 | 2025-03-14 | 四川大学华西医院 | 一种具有长效抑瘤效果的嵌合抗原受体t细胞及其制备方法和用途 |
| CN121294362A (zh) * | 2025-12-11 | 2026-01-09 | 良渚实验室 | Tada2b基因在促进红系终末分化中的应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019084495A1 (en) * | 2017-10-27 | 2019-05-02 | The Trustees Of The University Of Pennsylvania | IDENTIFICATION OF EPIGENETIC AND TRANSCRIPTIONAL TARGETS TO PREVENT AND REVERSE T-LYMPHOCYTE EXHAUST |
| US11400117B2 (en) * | 2017-12-15 | 2022-08-02 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for inhibiting T cell exhaustion |
| US11447769B2 (en) * | 2018-03-27 | 2022-09-20 | The Trustees Of The University Of Pennsylvania | Modified immune cells having enhanced function and methods for screening for same |
| CN110904045A (zh) * | 2018-09-17 | 2020-03-24 | 中国科学院动物研究所 | 经修饰的t细胞、其制备方法及用途 |
| US20220354889A1 (en) * | 2019-03-26 | 2022-11-10 | The Trustees Of The University Of Pennsylvania | Dnmt3a knockout car t cells for adoptive immunotherapy |
| WO2020219682A2 (en) * | 2019-04-24 | 2020-10-29 | St. Jude Children's Research Hospital, Inc. | Gene knock-outs to improve t cell function |
-
2022
- 2022-07-28 EP EP22850516.0A patent/EP4376858A4/en active Pending
- 2022-07-28 WO PCT/US2022/074251 patent/WO2023010073A1/en not_active Ceased
- 2022-07-28 CN CN202280052739.XA patent/CN117813102A/zh active Pending
- 2022-07-28 US US18/580,472 patent/US20240327826A1/en active Pending
- 2022-07-28 JP JP2024505066A patent/JP2024527997A/ja active Pending
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