JPWO2022236142A5 - - Google Patents
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- Publication number
- JPWO2022236142A5 JPWO2022236142A5 JP2023568216A JP2023568216A JPWO2022236142A5 JP WO2022236142 A5 JPWO2022236142 A5 JP WO2022236142A5 JP 2023568216 A JP2023568216 A JP 2023568216A JP 2023568216 A JP2023568216 A JP 2023568216A JP WO2022236142 A5 JPWO2022236142 A5 JP WO2022236142A5
- Authority
- JP
- Japan
- Prior art keywords
- cdr
- cells
- seq
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000003275 alpha amino acid group Chemical group 0.000 claims 23
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims 18
- 210000004027 cell Anatomy 0.000 claims 12
- 102000037865 fusion proteins Human genes 0.000 claims 10
- 108020001507 fusion proteins Proteins 0.000 claims 10
- 108010019670 Chimeric Antigen Receptors Proteins 0.000 claims 6
- 230000002401 inhibitory effect Effects 0.000 claims 5
- 206010028980 Neoplasm Diseases 0.000 claims 4
- 239000000427 antigen Substances 0.000 claims 4
- 102000036639 antigens Human genes 0.000 claims 4
- 108091007433 antigens Proteins 0.000 claims 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims 4
- 210000001744 T-lymphocyte Anatomy 0.000 claims 3
- 230000003834 intracellular effect Effects 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 101000743490 Homo sapiens V-set and immunoglobulin domain-containing protein 2 Proteins 0.000 claims 2
- 102100038295 V-set and immunoglobulin domain-containing protein 2 Human genes 0.000 claims 2
- 108700010039 chimeric receptor Proteins 0.000 claims 2
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 claims 2
- 210000001671 embryonic stem cell Anatomy 0.000 claims 2
- 210000004263 induced pluripotent stem cell Anatomy 0.000 claims 2
- 102000040430 polynucleotide Human genes 0.000 claims 2
- 108091033319 polynucleotide Proteins 0.000 claims 2
- 239000002157 polynucleotide Substances 0.000 claims 2
- 210000003171 tumor-infiltrating lymphocyte Anatomy 0.000 claims 2
- NFGXHKASABOEEW-UHFFFAOYSA-N 1-methylethyl 11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate Chemical compound COC(C)(C)CCCC(C)CC=CC(C)=CC(=O)OC(C)C NFGXHKASABOEEW-UHFFFAOYSA-N 0.000 claims 1
- 210000001266 CD8-positive T-lymphocyte Anatomy 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108091008874 T cell receptors Proteins 0.000 claims 1
- 102000016266 T-Cell Antigen Receptors Human genes 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 210000003719 b-lymphocyte Anatomy 0.000 claims 1
- 210000003651 basophil Anatomy 0.000 claims 1
- 210000001772 blood platelet Anatomy 0.000 claims 1
- 210000002798 bone marrow cell Anatomy 0.000 claims 1
- 210000004443 dendritic cell Anatomy 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 210000003979 eosinophil Anatomy 0.000 claims 1
- 210000003743 erythrocyte Anatomy 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 210000004475 gamma-delta t lymphocyte Anatomy 0.000 claims 1
- 210000003630 histaminocyte Anatomy 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 210000004964 innate lymphoid cell Anatomy 0.000 claims 1
- 230000004068 intracellular signaling Effects 0.000 claims 1
- 230000021633 leukocyte mediated immunity Effects 0.000 claims 1
- 210000002540 macrophage Anatomy 0.000 claims 1
- 210000001616 monocyte Anatomy 0.000 claims 1
- 210000000581 natural killer T-cell Anatomy 0.000 claims 1
- 210000000440 neutrophil Anatomy 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 210000001778 pluripotent stem cell Anatomy 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 210000003289 regulatory T cell Anatomy 0.000 claims 1
- 230000011664 signaling Effects 0.000 claims 1
- 125000006850 spacer group Chemical group 0.000 claims 1
- 230000004936 stimulating effect Effects 0.000 claims 1
- 210000002536 stromal cell Anatomy 0.000 claims 1
- 210000004881 tumor cell Anatomy 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163185896P | 2021-05-07 | 2021-05-07 | |
| US63/185,896 | 2021-05-07 | ||
| US202163283147P | 2021-11-24 | 2021-11-24 | |
| US63/283,147 | 2021-11-24 | ||
| PCT/US2022/028202 WO2022236142A2 (en) | 2021-05-07 | 2022-05-06 | Chimeric receptors and methods of use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024516713A JP2024516713A (ja) | 2024-04-16 |
| JPWO2022236142A5 true JPWO2022236142A5 (https=) | 2025-05-14 |
| JP2024516713A5 JP2024516713A5 (https=) | 2025-05-14 |
Family
ID=83933024
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023568216A Pending JP2024516713A (ja) | 2021-05-07 | 2022-05-06 | キメラ受容体およびその使用方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20240173410A1 (https=) |
| EP (1) | EP4334346A4 (https=) |
| JP (1) | JP2024516713A (https=) |
| KR (1) | KR20240004680A (https=) |
| AU (1) | AU2022270717A1 (https=) |
| CA (1) | CA3217614A1 (https=) |
| IL (1) | IL308148A (https=) |
| TW (1) | TW202309091A (https=) |
| WO (1) | WO2022236142A2 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12264189B2 (en) | 2018-10-31 | 2025-04-01 | Mayo Foundation For Medical Education And Research | Methods and materials for treating cancer |
| WO2020092736A1 (en) | 2018-10-31 | 2020-05-07 | Mayo Foundation For Medical Education And Research | Methods and materials for treating cancer |
| EP4698564A2 (en) * | 2023-04-17 | 2026-02-25 | Senti Biosciences, Inc. | Antigen-binding domains and methods of use thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2014014951A (es) * | 2012-06-06 | 2015-03-13 | Oncomed Pharm Inc | Agentes aglutinantes que modulan la trayectoria hippo y sus usos. |
| WO2019024979A1 (en) * | 2017-07-31 | 2019-02-07 | Institute For Research In Biomedicine | FUNCTIONAL DOMAIN ANTIBODIES IN THE ELBOW REGION |
| JP7682797B2 (ja) * | 2019-03-20 | 2025-05-26 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | クローディン６二重特異性抗体 |
| EP3962527A4 (en) * | 2019-04-30 | 2023-11-01 | Senti Biosciences, Inc. | CHIMERIC RECEPTORS AND METHODS OF USE THEREOF |
| CN111378037B (zh) * | 2020-06-01 | 2020-09-01 | 南京诺艾新生物技术有限公司 | 一种抗hIL-33人源化单抗及其应用 |
-
2022
- 2022-05-06 KR KR1020237040933A patent/KR20240004680A/ko active Pending
- 2022-05-06 TW TW111117214A patent/TW202309091A/zh unknown
- 2022-05-06 AU AU2022270717A patent/AU2022270717A1/en active Pending
- 2022-05-06 EP EP22799728.5A patent/EP4334346A4/en active Pending
- 2022-05-06 IL IL308148A patent/IL308148A/en unknown
- 2022-05-06 WO PCT/US2022/028202 patent/WO2022236142A2/en not_active Ceased
- 2022-05-06 CA CA3217614A patent/CA3217614A1/en active Pending
- 2022-05-06 JP JP2023568216A patent/JP2024516713A/ja active Pending
-
2023
- 2023-11-07 US US18/504,037 patent/US20240173410A1/en active Pending
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