JPWO2022190626A1 - - Google Patents

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Publication number
JPWO2022190626A1
JPWO2022190626A1 JP2023505158A JP2023505158A JPWO2022190626A1 JP WO2022190626 A1 JPWO2022190626 A1 JP WO2022190626A1 JP 2023505158 A JP2023505158 A JP 2023505158A JP 2023505158 A JP2023505158 A JP 2023505158A JP WO2022190626 A1 JPWO2022190626 A1 JP WO2022190626A1
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2023505158A
Other languages
Japanese (ja)
Other versions
JPWO2022190626A5 (https=
JP7626491B2 (ja
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Publication of JPWO2022190626A1 publication Critical patent/JPWO2022190626A1/ja
Publication of JPWO2022190626A5 publication Critical patent/JPWO2022190626A5/ja
Application granted granted Critical
Publication of JP7626491B2 publication Critical patent/JP7626491B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5192Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
JP2023505158A 2021-03-12 2022-01-14 Sn-38誘導体、当該誘導体を含むナノ粒子、医薬及び当該ナノ粒子の製造方法 Active JP7626491B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021040799 2021-03-12
JP2021040799 2021-03-12
PCT/JP2022/001163 WO2022190626A1 (ja) 2021-03-12 2022-01-14 Sn-38誘導体、当該誘導体を含むナノ粒子、医薬及び当該ナノ粒子の製造方法

Publications (3)

Publication Number Publication Date
JPWO2022190626A1 true JPWO2022190626A1 (https=) 2022-09-15
JPWO2022190626A5 JPWO2022190626A5 (https=) 2024-05-01
JP7626491B2 JP7626491B2 (ja) 2025-02-04

Family

ID=83226544

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023505158A Active JP7626491B2 (ja) 2021-03-12 2022-01-14 Sn-38誘導体、当該誘導体を含むナノ粒子、医薬及び当該ナノ粒子の製造方法

Country Status (6)

Country Link
US (1) US20240300979A1 (https=)
EP (1) EP4306527A4 (https=)
JP (1) JP7626491B2 (https=)
CN (1) CN117015545A (https=)
AU (1) AU2022234045B2 (https=)
WO (1) WO2022190626A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115844891B (zh) * 2022-11-04 2025-02-11 沈阳药科大学 二硫键桥连的sn38二聚体前药及其自组装纳米粒、制备方法与应用
AU2023390747A1 (en) 2022-12-09 2025-06-26 Japan Science And Technology Agency Compound, nanoparticles, medicine and method for producing nanoparticles

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011155501A1 (ja) * 2010-06-11 2011-12-15 独立行政法人科学技術振興機構 薬剤多量体微粒子及びその製造方法
JP2016534092A (ja) * 2013-07-23 2016-11-04 イミューノメディクス、インコーポレイテッドImmunomedics, Inc. Cl2aリンカーを有する抗体−sn−38免疫複合体
CN107669626A (zh) * 2017-09-03 2018-02-09 河南师范大学 一种高载药量的还原敏感的药物传递系统的制备方法及其应用
JP2018520148A (ja) * 2012-12-13 2018-07-26 イミューノメディクス、インコーポレイテッドImmunomedics, Inc. Cl2aリンカーを有する抗体−sn−38免疫抱合体
WO2019236954A1 (en) * 2018-06-07 2019-12-12 Seattle Genetics, Inc. Camptothecin conjugates

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021040799A (ja) 2019-09-09 2021-03-18 西川 基守 パチンコ遊技機

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011155501A1 (ja) * 2010-06-11 2011-12-15 独立行政法人科学技術振興機構 薬剤多量体微粒子及びその製造方法
JP2018520148A (ja) * 2012-12-13 2018-07-26 イミューノメディクス、インコーポレイテッドImmunomedics, Inc. Cl2aリンカーを有する抗体−sn−38免疫抱合体
JP2016534092A (ja) * 2013-07-23 2016-11-04 イミューノメディクス、インコーポレイテッドImmunomedics, Inc. Cl2aリンカーを有する抗体−sn−38免疫複合体
CN107669626A (zh) * 2017-09-03 2018-02-09 河南师范大学 一种高载药量的还原敏感的药物传递系统的制备方法及其应用
WO2019236954A1 (en) * 2018-06-07 2019-12-12 Seattle Genetics, Inc. Camptothecin conjugates

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GUO, X. ET AL.: "Dimeric Drug Polymeric Micelles with Acid-Active Tumor Targeting and FRET-Traceable Drug Release", ADVANCED MATERIALS, vol. 30, no. 3, JPN6022009149, 2018, pages 1705436 - 1, ISSN: 0005334187 *
HE, D. ET AL.: "Self-assembling nanowires of an amphiphilic camptothecin prodrug derived from homologous derivative", CHEMICAL COMMUNICATIONS, vol. 52, no. 98, JPN7022001040, 2016, pages 14145 - 14148, ISSN: 0005334185 *
WANG, H. ET AL.: "Reduction-Responsive Dithiomaleimide-Based Nanomedicine with High Drug Loading and FRET-Indicated Dr", CHEMICAL COMMUNICATIONS, vol. 51, no. 23, JPN7022001039, 2015, pages 4807 - 4810, ISSN: 0005334186 *

Also Published As

Publication number Publication date
WO2022190626A1 (ja) 2022-09-15
EP4306527A4 (en) 2025-02-19
US20240300979A1 (en) 2024-09-12
AU2022234045A1 (en) 2023-08-31
JP7626491B2 (ja) 2025-02-04
EP4306527A1 (en) 2024-01-17
AU2022234045B2 (en) 2025-05-29
CN117015545A (zh) 2023-11-07

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