JPWO2022149610A1 - - Google Patents
Info
- Publication number
- JPWO2022149610A1 JPWO2022149610A1 JP2022574078A JP2022574078A JPWO2022149610A1 JP WO2022149610 A1 JPWO2022149610 A1 JP WO2022149610A1 JP 2022574078 A JP2022574078 A JP 2022574078A JP 2022574078 A JP2022574078 A JP 2022574078A JP WO2022149610 A1 JPWO2022149610 A1 JP WO2022149610A1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1075—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of amino acids or peptide residues
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025191313A JP2026027427A (ja) | 2021-01-07 | 2025-11-11 | 新規グアニジン誘導体及びその製造方法 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021001758 | 2021-01-07 | ||
| PCT/JP2022/000356 WO2022149610A1 (ja) | 2021-01-07 | 2022-01-07 | 新規グアニジン誘導体及びその製造方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025191313A Division JP2026027427A (ja) | 2021-01-07 | 2025-11-11 | 新規グアニジン誘導体及びその製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2022149610A1 true JPWO2022149610A1 (https=) | 2022-07-14 |
| JPWO2022149610A5 JPWO2022149610A5 (https=) | 2023-12-28 |
Family
ID=82357978
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022574078A Pending JPWO2022149610A1 (https=) | 2021-01-07 | 2022-01-07 | |
| JP2025191313A Pending JP2026027427A (ja) | 2021-01-07 | 2025-11-11 | 新規グアニジン誘導体及びその製造方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025191313A Pending JP2026027427A (ja) | 2021-01-07 | 2025-11-11 | 新規グアニジン誘導体及びその製造方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20240010627A1 (https=) |
| EP (1) | EP4276096A4 (https=) |
| JP (2) | JPWO2022149610A1 (https=) |
| WO (1) | WO2022149610A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118978459B (zh) * | 2024-10-21 | 2025-01-28 | 安徽昊帆生物有限公司 | Fmoc-L-Lys(ivDde)-OH的制备方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08509970A (ja) * | 1993-05-06 | 1996-10-22 | ザ ウエルカム ファウンデーション リミテッド | Ｎｇ−モノアルキル−ｌ−アルギニンおよび関連化合物の製造法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101993475A (zh) * | 2009-08-21 | 2011-03-30 | 杭州诺泰制药技术有限公司 | 一种全液相依替巴肽(Eptifibatide)的合成方法 |
| CN102040652A (zh) * | 2009-10-12 | 2011-05-04 | 杭州诺泰制药技术有限公司 | 一种固液相结合依替巴肽(Eptifibatide)的合成方法 |
| US20150197500A1 (en) * | 2014-01-14 | 2015-07-16 | Euclises Pharmaceuticals, Inc. | No-releasing guanidine-chromene conjugates |
-
2022
- 2022-01-07 US US18/271,200 patent/US20240010627A1/en active Pending
- 2022-01-07 JP JP2022574078A patent/JPWO2022149610A1/ja active Pending
- 2022-01-07 WO PCT/JP2022/000356 patent/WO2022149610A1/ja not_active Ceased
- 2022-01-07 EP EP22736778.6A patent/EP4276096A4/en active Pending
-
2025
- 2025-11-11 JP JP2025191313A patent/JP2026027427A/ja active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08509970A (ja) * | 1993-05-06 | 1996-10-22 | ザ ウエルカム ファウンデーション リミテッド | Ｎｇ−モノアルキル−ｌ−アルギニンおよび関連化合物の製造法 |
Non-Patent Citations (9)
| Title |
|---|
| ABBOUR, S. AND BAUDY-FLOCH, M.: "Fmoc-aza-β3-Lys-OAllyl and Fmoc-aza-β3-Asp-OAllyl for on-resin head-to-tail cyclization of aza-β3", TETRAHEDRON LETTERS, vol. 54, JPN6022010416, 2013, pages 775 - 778, ISSN: 0005597250 * |
| HOSSEINI, M. ET AL.: "Elucidation of the Contribution of Active Site and Exosite Interactions to Affinity and Specificity", MOLECULAR PHARMACOLOGY, vol. 80, no. 4, JPN6022010408, 2011, pages 585 - 597, ISSN: 0005597244 * |
| LEE, Y. ET AL.: "Brain gene delivery using histidine and arginine-modified dendrimers for ischemic stroke therapy", JOURNAL OF CONTROLLED RELEASE, vol. 330, JPN6022010412, 2020, pages 907 - 919, ISSN: 0005597247 * |
| NODA, M. AND KIFFE, M.: "New mild acid-labile protecting group for the guanidino function of Nα-fluorenylmethoxycarbonyl-L-a", J. PEPTIDE RES., vol. 50, JPN6022010413, 1997, pages 329 - 335, ISSN: 0005597248 * |
| PATINO, N. ET AL.: "Modelling, synthesis and biological evaluation of an ethidium-arginine conjugate linked to a ribonuc", EUR. J. MED. CHEM., vol. 37, JPN6022010411, 2002, pages 573 - 584, ISSN: 0005597246 * |
| RUTENBER, E. E. ET AL.: "The Discovery, Characterization and Crystallographically Determined Binding Mode of an FMOC-Containi", BIOORGANIC & MEDICINAL CHEMISTRY, vol. 5, no. 7, JPN6022010409, 1997, pages 1311 - 1320, ISSN: 0005597245 * |
| WANGLER, B. ET AL.: "Aiming at the tumor-specific accumulation of MGMT-inhibitors: First description of a synthetic strat", TETRAHEDRON LETTERS, vol. 61, JPN6022010417, 2020, pages 151840, ISSN: 0005597251 * |
| ZHANG, Y. ET AL.: "Peptidic transition state analogues as PRMT inhibitors", METHODS, vol. 175, JPN6022010419, 2020, pages 24 - 29, ISSN: 0005597252 * |
| 野田昌樹・ミハエル キッフェ: "ジベンゾスベリル基及びジベンゾスベレニル基のペプチド固相合成におけるアミノ保護基への応用（第２報）", 島津評論, vol. 54, no. 3, JPN6022010415, 1997, pages 223 - 229, ISSN: 0005597249 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP4276096A1 (en) | 2023-11-15 |
| JP2026027427A (ja) | 2026-02-18 |
| EP4276096A4 (en) | 2025-03-26 |
| US20240010627A1 (en) | 2024-01-11 |
| WO2022149610A1 (ja) | 2022-07-14 |
Similar Documents
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20230518 |
|
| AA64 | Notification of invalidation of claim of internal priority (with term) |
Free format text: JAPANESE INTERMEDIATE CODE: A241764 Effective date: 20230926 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20231013 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20231129 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20241217 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20250520 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20250709 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20250812 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20251111 |