JPWO2022140150A5 - - Google Patents

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Publication number
JPWO2022140150A5
JPWO2022140150A5 JP2023537550A JP2023537550A JPWO2022140150A5 JP WO2022140150 A5 JPWO2022140150 A5 JP WO2022140150A5 JP 2023537550 A JP2023537550 A JP 2023537550A JP 2023537550 A JP2023537550 A JP 2023537550A JP WO2022140150 A5 JPWO2022140150 A5 JP WO2022140150A5
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JP
Japan
Prior art keywords
cell
fusion polypeptide
item
target site
deletion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023537550A
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English (en)
Japanese (ja)
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JP2024503249A (ja
JP2024503249A5 (https=
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/063771 external-priority patent/WO2022140150A1/en
Publication of JP2024503249A publication Critical patent/JP2024503249A/ja
Publication of JP2024503249A5 publication Critical patent/JP2024503249A5/ja
Publication of JPWO2022140150A5 publication Critical patent/JPWO2022140150A5/ja
Pending legal-status Critical Current

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JP2023537550A 2020-12-21 2021-12-16 部位特異的変異導入のための組成物及び方法 Pending JP2024503249A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063128391P 2020-12-21 2020-12-21
US63/128,391 2020-12-21
PCT/US2021/063771 WO2022140150A1 (en) 2020-12-21 2021-12-16 Compositions and methods for site-directed mutagenesis

Publications (3)

Publication Number Publication Date
JP2024503249A JP2024503249A (ja) 2024-01-25
JP2024503249A5 JP2024503249A5 (https=) 2024-12-23
JPWO2022140150A5 true JPWO2022140150A5 (https=) 2024-12-23

Family

ID=82158380

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023537550A Pending JP2024503249A (ja) 2020-12-21 2021-12-16 部位特異的変異導入のための組成物及び方法

Country Status (8)

Country Link
US (1) US20240336904A1 (https=)
EP (1) EP4262850A4 (https=)
JP (1) JP2024503249A (https=)
KR (1) KR20230122628A (https=)
CN (1) CN116887853A (https=)
AU (1) AU2021410632A1 (https=)
CA (1) CA3202889A1 (https=)
WO (1) WO2022140150A1 (https=)

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012118717A2 (en) * 2011-02-28 2012-09-07 Seattle Children's Research Institute Coupling endonucleases with end-processing enzymes drive high efficiency gene disruption
RU2650811C2 (ru) * 2012-02-24 2018-04-17 Фред Хатчинсон Кэнсер Рисерч Сентер Композиции и способы лечения гемоглобинопатии
US10000746B2 (en) * 2013-05-31 2018-06-19 Cellectis LAGLIDADG homing endonuclease cleaving the T cell receptor alpha gene and uses thereof
US20180119174A1 (en) * 2015-05-13 2018-05-03 Seattle Children's Hospita (dba Seattle Children's Research Institute Enhancing endonuclease based gene editing in primary cells
MX2018010924A (es) * 2016-03-11 2019-02-13 Bluebird Bio Inc Células efectoras inmunitarias con edición genómica.
WO2018071565A1 (en) * 2016-10-11 2018-04-19 Bluebird Bio, Inc. TCRa HOMING ENDONUCLEASE VARIANTS
IL313037A (en) * 2017-05-25 2024-07-01 2Seventy Bio Inc Cblb endonuclease variants, compositions, and methods of use
CN112533627A (zh) * 2018-03-27 2021-03-19 G+Flas 生命科学公司 序列特异性体内细胞靶向
WO2020072059A1 (en) * 2018-10-04 2020-04-09 Bluebird Bio, Inc. Cblb endonuclease variants, compositions, and methods of use
WO2020123371A2 (en) * 2018-12-10 2020-06-18 Bluebird Bio, Inc. Homing endonuclease variants
US20220280567A1 (en) * 2019-06-14 2022-09-08 2Seventy Bio, Inc. Compositions and methods for treating cancer

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