JPWO2022040600A5 - - Google Patents
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- Publication number
- JPWO2022040600A5 JPWO2022040600A5 JP2023512462A JP2023512462A JPWO2022040600A5 JP WO2022040600 A5 JPWO2022040600 A5 JP WO2022040600A5 JP 2023512462 A JP2023512462 A JP 2023512462A JP 2023512462 A JP2023512462 A JP 2023512462A JP WO2022040600 A5 JPWO2022040600 A5 JP WO2022040600A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- halo
- pharma
- alkyl
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063068870P | 2020-08-21 | 2020-08-21 | |
| US63/068,870 | 2020-08-21 | ||
| PCT/US2021/047015 WO2022040600A1 (en) | 2020-08-21 | 2021-08-20 | Compounds as glp-1r agonists |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023538408A JP2023538408A (ja) | 2023-09-07 |
| JPWO2022040600A5 true JPWO2022040600A5 (https=) | 2024-08-26 |
| JP2023538408A5 JP2023538408A5 (https=) | 2024-08-26 |
Family
ID=80350630
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023512462A Pending JP2023538408A (ja) | 2020-08-21 | 2021-08-20 | Ｇｌｐ－１ｒ作動薬としての化合物 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20230322744A1 (https=) |
| EP (1) | EP4199919A4 (https=) |
| JP (1) | JP2023538408A (https=) |
| KR (1) | KR20230074486A (https=) |
| CN (1) | CN116507326A (https=) |
| AU (1) | AU2021327397A1 (https=) |
| BR (1) | BR112023003168A2 (https=) |
| CA (1) | CA3192601A1 (https=) |
| CL (2) | CL2023000516A1 (https=) |
| CO (1) | CO2023003322A2 (https=) |
| IL (1) | IL300795A (https=) |
| MX (1) | MX2023002108A (https=) |
| PE (1) | PE20231206A1 (https=) |
| TW (1) | TWI905252B (https=) |
| WO (1) | WO2022040600A1 (https=) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3157525A1 (en) | 2019-10-25 | 2021-04-29 | Gilead Sciences, Inc. | Glp-1r modulating compounds |
| WO2021154796A1 (en) | 2020-01-29 | 2021-08-05 | Gilead Sciences, Inc. | Glp-1r modulating compounds |
| FI4143183T3 (fi) | 2020-04-29 | 2026-01-07 | Gasherbrum Bio Inc | Heterosyklisiä glp-1-agonisteja |
| PE20231181A1 (es) | 2020-08-06 | 2023-08-11 | Gasherbrum Bio Inc | Agonistas del glp-1 heterociclicos |
| WO2022042691A1 (en) | 2020-08-28 | 2022-03-03 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
| AU2021306414B2 (en) | 2020-09-01 | 2026-01-29 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | Fused imidazole derivative, preparation method therefor, and medical use thereof |
| EP4247804A1 (en) | 2020-11-20 | 2023-09-27 | Gilead Sciences, Inc. | Polyheterocyclic glp-1 r modulating compounds |
| CA3209593A1 (en) * | 2021-01-28 | 2022-08-04 | Carmot Therapeutics, Inc. | Gpcr receptor agonists, pharmaceutical compositions comprising the same, and methods for their use |
| WO2022184849A1 (en) * | 2021-03-04 | 2022-09-09 | Les Laboratoires Servier | Glp-1r agonists, uses and pharmaceutical compositions thereof |
| WO2022192430A1 (en) * | 2021-03-11 | 2022-09-15 | Gilead Sciences, Inc. | Glp-1r modulating compounds |
| EP4304711A1 (en) * | 2021-03-11 | 2024-01-17 | Gilead Sciences, Inc. | Glp-1r modulating compounds |
| CN116940561A (zh) * | 2021-03-22 | 2023-10-24 | 杭州中美华东制药有限公司 | 噻吩类glp-1受体激动剂及其用途 |
| WO2022202864A1 (ja) | 2021-03-24 | 2022-09-29 | 塩野義製薬株式会社 | 縮合環を有するｇｌｐ－１受容体作動薬を含有する医薬組成物 |
| WO2022199661A1 (en) * | 2021-03-24 | 2022-09-29 | Eccogene (Shanghai) Co., Ltd. | Phenyl- [1, 3] dioxolo [4, 5-c] pyridinyl-phenyl-, phenyl- [1, 3] dioxolo [4, 5-c] pyridinyl-heteroaryl-, or phenyl- [1, 3] dioxolo [4, 5-c] pyridinyl-piperidinyl-methyl-oxetanylmethyl-1h-benzo [d] imidazole-carboxylic acid derivatives and methods of using same |
| PH12023552860A1 (en) | 2021-04-21 | 2024-05-20 | Gilead Sciences Inc | Carboxy-benzimidazole glp-1r modulating compounds |
| TWI843104B (zh) | 2021-05-20 | 2024-05-21 | 美商美國禮來大藥廠 | 類升糖素肽1受體促效劑 |
| EP4382525A4 (en) * | 2021-08-04 | 2025-07-16 | Shanghai Hansoh Biomedical Co Ltd | CYCLOALKENE DERIVATIVE REGULATOR, PREPARATION METHOD AND USE THEREOF |
| WO2023038039A1 (ja) | 2021-09-08 | 2023-03-16 | 塩野義製薬株式会社 | 抗肥満作用の関与する疾患の予防及び治療用医薬 |
| KR20240068737A (ko) | 2021-09-27 | 2024-05-17 | 테른스 파마슈티칼스, 인크. | Glp-1r 효능제로서의 벤즈이미다졸 카복실산 |
| WO2023057414A1 (en) | 2021-10-05 | 2023-04-13 | Astrazeneca Ab | Certain octahydrofuro[3,4- b]pyrazines as glp-1 receptor modulators |
| AU2022358915A1 (en) | 2021-10-05 | 2024-05-09 | Astrazeneca Ab | Certain 2,5-diazabicyclo[4.2.0]octanes as glp-1 receptor modulators |
| WO2023057429A1 (en) | 2021-10-05 | 2023-04-13 | Astrazeneca Ab | Certain 2,5-diazabicyclo[4.2.0]octanes and octahydrofuro[3,4- b]pyrazines as glp-1 receptor modulators |
| AU2022375634A1 (en) | 2021-10-25 | 2024-06-06 | Terns Pharmaceuticals, Inc. | Compounds as glp-1r agonists |
| US20250066338A1 (en) | 2021-12-16 | 2025-02-27 | Astrazeneca Ab | Certain 3-azabicyclo[3.1.0]hexanes as glp-1 receptor modulators |
| WO2023111145A1 (en) | 2021-12-16 | 2023-06-22 | Astrazeneca Ab | Certain 3-azabicyclo[3.1.0]hexanes as glp-1 receptor modulators |
| KR20240150488A (ko) | 2022-02-23 | 2024-10-15 | 테른스 파마슈티칼스, 인크. | Glp-1r 작용제로서의 화합물 |
| WO2023182869A1 (en) * | 2022-03-25 | 2023-09-28 | Ildong Pharmaceutical Co., Ltd. | Novel salt of glp-1 receptor agonist compound, preparation method thereof and pharmaceutical composition comprising thereof |
| US20250136584A1 (en) * | 2022-05-20 | 2025-05-01 | Chengdu Di'ao Jiuhong Pharmaceutical Factory | Benzimidazole Or Azabenzimidazole Compound, Preparation Method Therefor And Use Thereof |
| CN117003744B (zh) * | 2022-07-18 | 2025-08-15 | 厦门市博瑞来医药科技有限公司 | 五元并六元化合物、其中间体、制备方法、组合物和应用 |
| US20260097037A1 (en) | 2022-09-22 | 2026-04-09 | Shionogi & Co., Ltd. | Fused ring compound having glp-1 receptor agonist effect |
| JPWO2024063140A1 (https=) * | 2022-09-22 | 2024-03-28 | ||
| CN116102543B (zh) * | 2022-10-21 | 2025-07-22 | 江南大学 | 一种glp-1r激动剂、合成方法及其用途 |
| WO2024102625A1 (en) | 2022-11-11 | 2024-05-16 | Eli Lilly And Company | Glucagon-like peptide 1 receptor agonists |
| IL320810A (en) | 2022-11-16 | 2025-07-01 | Lilly Co Eli | Glucagon-like peptide 1 receptor agonists |
| EP4660194A1 (en) * | 2023-02-02 | 2025-12-10 | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. | Salt and crystal form of cycloalkene compound, and preparation method therefor and use thereof |
| US20240398794A1 (en) | 2023-04-07 | 2024-12-05 | Terns Pharmaceuticals, Inc. | COMBINATIONS OF GLP-1R AND THRß AGONISTS AND METHODS OF USE THEREOF |
| WO2024212742A1 (zh) * | 2023-04-10 | 2024-10-17 | 上海研健新药研发有限公司 | 一种glp-1r激动剂，其制备方法和应用 |
| TW202521533A (zh) | 2023-09-14 | 2025-06-01 | 香港商歌禮製藥(中國)有限公司 | Glp-1r 激動劑及其治療方法 |
| CN121889388A (zh) * | 2023-09-21 | 2026-04-17 | 尹诺卫医药有限公司 | 制备取代的稠合咪唑衍生物的方法 |
| US12291530B1 (en) | 2023-11-24 | 2025-05-06 | Ascletis Pharma (China) Co., Limited | GLP-1R agonist and therapeutic method thereof |
| WO2025189141A1 (en) | 2024-03-08 | 2025-09-12 | Annapurna Bio, Inc. | Methods for treating obesity and increasing weight loss |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3555064B9 (en) * | 2016-12-16 | 2023-03-01 | Pfizer Inc. | Glp-1 receptor agonists and uses thereof |
| ES2943510T3 (es) * | 2018-06-15 | 2023-06-13 | Pfizer | Agonistas del receptor GLP-1 y usos del mismo |
| CR20210110A (es) * | 2018-08-31 | 2021-05-13 | Pfizer | Combinaciones para tratamiento de ehna/ehgna y enfermedades relacionadas |
| CR20210341A (es) * | 2018-11-22 | 2021-11-25 | Qilu Regor Therapeutics Inc | Agonistas de glp-ir y usos de los mismos |
| JP7386997B2 (ja) * | 2019-11-15 | 2023-11-27 | イルドン ファーマシューティカル カンパニー リミテッド | Ｇｌｐ－１受容体アゴニストおよびその使用 |
| WO2022235717A1 (en) * | 2021-05-03 | 2022-11-10 | Carmot Therapeutics, Inc. | Benzimidazoyl glp-1 receptor agonists, pharmaceutical compositions comprising the same, and methods for their use |
| WO2023001237A1 (en) * | 2021-07-21 | 2023-01-26 | Hepagene Therapeutics (HK) Limited | Glucagon-like peptide-1 receptor modulators and uses thereof |
-
2021
- 2021-08-20 PE PE2023000511A patent/PE20231206A1/es unknown
- 2021-08-20 JP JP2023512462A patent/JP2023538408A/ja active Pending
- 2021-08-20 WO PCT/US2021/047015 patent/WO2022040600A1/en not_active Ceased
- 2021-08-20 BR BR112023003168A patent/BR112023003168A2/pt unknown
- 2021-08-20 AU AU2021327397A patent/AU2021327397A1/en active Pending
- 2021-08-20 EP EP21859247.5A patent/EP4199919A4/en active Pending
- 2021-08-20 CA CA3192601A patent/CA3192601A1/en active Pending
- 2021-08-20 US US18/042,443 patent/US20230322744A1/en active Pending
- 2021-08-20 MX MX2023002108A patent/MX2023002108A/es unknown
- 2021-08-20 KR KR1020237009681A patent/KR20230074486A/ko not_active Withdrawn
- 2021-08-20 CN CN202180071858.5A patent/CN116507326A/zh active Pending
- 2021-08-20 TW TW110130936A patent/TWI905252B/zh active
- 2021-08-20 US US17/445,588 patent/US20220089578A1/en not_active Abandoned
- 2021-08-20 IL IL300795A patent/IL300795A/en unknown
-
2023
- 2023-02-21 CL CL2023000516A patent/CL2023000516A1/es unknown
- 2023-03-17 CO CONC2023/0003322A patent/CO2023003322A2/es unknown
-
2024
- 2024-04-05 CL CL2024001025A patent/CL2024001025A1/es unknown
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