JPWO2022014639A5 - - Google Patents
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- Publication number
- JPWO2022014639A5 JPWO2022014639A5 JP2022536419A JP2022536419A JPWO2022014639A5 JP WO2022014639 A5 JPWO2022014639 A5 JP WO2022014639A5 JP 2022536419 A JP2022536419 A JP 2022536419A JP 2022536419 A JP2022536419 A JP 2022536419A JP WO2022014639 A5 JPWO2022014639 A5 JP WO2022014639A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl group
- hydrogen atom
- group optionally
- general formula
- substituent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020121525 | 2020-07-15 | ||
| JP2020121525 | 2020-07-15 | ||
| PCT/JP2021/026461 WO2022014639A1 (ja) | 2020-07-15 | 2021-07-14 | Ｅｇｆｒ阻害剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2022014639A1 JPWO2022014639A1 (https=) | 2022-01-20 |
| JPWO2022014639A5 true JPWO2022014639A5 (https=) | 2023-03-27 |
| JP7495983B2 JP7495983B2 (ja) | 2024-06-05 |
Family
ID=79554696
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022536419A Active JP7495983B2 (ja) | 2020-07-15 | 2021-07-14 | Ｅｇｆｒ阻害剤 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20230285397A1 (https=) |
| EP (1) | EP4197538A4 (https=) |
| JP (1) | JP7495983B2 (https=) |
| KR (1) | KR102873219B1 (https=) |
| CN (1) | CN116368136B (https=) |
| AU (1) | AU2021309779B2 (https=) |
| BR (1) | BR112023000770A2 (https=) |
| CA (1) | CA3189460A1 (https=) |
| MX (1) | MX2023000693A (https=) |
| PH (1) | PH12023550119A1 (https=) |
| TW (1) | TW202216152A (https=) |
| WO (1) | WO2022014639A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4183395A4 (en) * | 2020-07-15 | 2024-07-24 | Taiho Pharmaceutical Co., Ltd. | PYRIMIDINE COMPOUND-CONTAINING COMBINATION FOR USE IN TUMOR TREATMENT |
| BR112023000765A2 (pt) * | 2020-07-15 | 2023-02-07 | Taiho Pharmaceutical Co Ltd | Cristal de composto de pirimidina |
| EP4351737A4 (en) * | 2021-05-24 | 2025-05-14 | Taiho Pharmaceutical Co., Ltd. | Treatment methods for subjects with cancer having an aberration in egfr and/or her2 |
| EP4687905A1 (en) | 2023-03-30 | 2026-02-11 | Revolution Medicines, Inc. | Compositions for inducing ras gtp hydrolysis and uses thereof |
| AU2024265078A1 (en) | 2023-05-04 | 2025-12-11 | Revolution Medicines, Inc. | Combination therapy for a ras related disease or disorder |
| IL326136A (en) | 2023-08-07 | 2026-03-01 | Revolution Medicines Inc | RMC-6291 for use in the treatment of a disease or disorder associated with the RAS protein |
| US20250154171A1 (en) | 2023-10-12 | 2025-05-15 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2025171296A1 (en) | 2024-02-09 | 2025-08-14 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2025240847A1 (en) | 2024-05-17 | 2025-11-20 | Revolution Medicines, Inc. | Ras inhibitors |
| US20250375445A1 (en) | 2024-06-07 | 2025-12-11 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
| WO2025265060A1 (en) | 2024-06-21 | 2025-12-26 | Revolution Medicines, Inc. | Therapeutic compositions and methods for managing treatment-related effects |
| WO2026006747A1 (en) | 2024-06-28 | 2026-01-02 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026015825A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Use of ras inhibitor for treating pancreatic cancer |
| WO2026015796A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015801A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015790A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026050446A1 (en) | 2024-08-29 | 2026-03-05 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026072904A2 (en) | 2024-09-26 | 2026-04-02 | Revolution Medicines, Inc. | Compositions and methods for treating lung cancer |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8426428B2 (en) * | 2008-12-05 | 2013-04-23 | Principia Biopharma, Inc. | EGFR kinase knockdown via electrophilically enhanced inhibitors |
| US9034885B2 (en) * | 2012-01-13 | 2015-05-19 | Acea Biosciences Inc. | EGFR modulators and uses thereof |
| TW201336847A (zh) | 2012-02-07 | 2013-09-16 | Taiho Pharmaceutical Co Ltd | 喹啉基吡咯并嘧啶化合物或其鹽 |
| BR112018004175B8 (pt) | 2015-09-01 | 2023-10-31 | Taiho Pharmaceutical Co Ltd | Composto pirazolo[3,4-d]pirimidina, composição farmacêutica e usos terapêuticos do dito composto |
| ES2775751T3 (es) * | 2016-02-23 | 2020-07-28 | Taiho Pharmaceutical Co Ltd | Nuevo compuesto de pirimidina condensada o sal del mismo |
| PL3909584T3 (pl) * | 2019-01-11 | 2024-03-25 | Taiho Pharmaceutical Co., Ltd. | Związek pirymidynowy lub jego sól |
-
2021
- 2021-07-14 MX MX2023000693A patent/MX2023000693A/es unknown
- 2021-07-14 AU AU2021309779A patent/AU2021309779B2/en active Active
- 2021-07-14 CN CN202180061165.8A patent/CN116368136B/zh active Active
- 2021-07-14 CA CA3189460A patent/CA3189460A1/en active Pending
- 2021-07-14 EP EP21842292.1A patent/EP4197538A4/en not_active Withdrawn
- 2021-07-14 WO PCT/JP2021/026461 patent/WO2022014639A1/ja not_active Ceased
- 2021-07-14 TW TW110125853A patent/TW202216152A/zh unknown
- 2021-07-14 BR BR112023000770A patent/BR112023000770A2/pt unknown
- 2021-07-14 US US18/016,103 patent/US20230285397A1/en active Pending
- 2021-07-14 KR KR1020237001973A patent/KR102873219B1/ko active Active
- 2021-07-14 JP JP2022536419A patent/JP7495983B2/ja active Active
- 2021-07-14 PH PH1/2023/550119A patent/PH12023550119A1/en unknown
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