JPWO2021132591A5 - - Google Patents

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Publication number
JPWO2021132591A5
JPWO2021132591A5 JP2021567687A JP2021567687A JPWO2021132591A5 JP WO2021132591 A5 JPWO2021132591 A5 JP WO2021132591A5 JP 2021567687 A JP2021567687 A JP 2021567687A JP 2021567687 A JP2021567687 A JP 2021567687A JP WO2021132591 A5 JPWO2021132591 A5 JP WO2021132591A5
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JP
Japan
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invention described
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Pending
Application number
JP2021567687A
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English (en)
Japanese (ja)
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JPWO2021132591A1 (enExample
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Application filed filed Critical
Priority claimed from PCT/JP2020/048803 external-priority patent/WO2021132591A1/ja
Publication of JPWO2021132591A1 publication Critical patent/JPWO2021132591A1/ja
Priority to JP2022097020A priority Critical patent/JP7201192B2/ja
Publication of JPWO2021132591A5 publication Critical patent/JPWO2021132591A5/ja
Pending legal-status Critical Current

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JP2021567687A 2019-12-26 2020-12-25 Pending JPWO2021132591A1 (enExample)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022097020A JP7201192B2 (ja) 2019-12-26 2022-06-16 エクソン50のスキッピングを誘導するアンチセンス核酸

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2019236704 2019-12-26
PCT/JP2020/048803 WO2021132591A1 (ja) 2019-12-26 2020-12-25 エクソン50のスキッピングを誘導するアンチセンス核酸

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022097020A Division JP7201192B2 (ja) 2019-12-26 2022-06-16 エクソン50のスキッピングを誘導するアンチセンス核酸

Publications (2)

Publication Number Publication Date
JPWO2021132591A1 JPWO2021132591A1 (enExample) 2021-07-01
JPWO2021132591A5 true JPWO2021132591A5 (enExample) 2024-01-09

Family

ID=76574765

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021567687A Pending JPWO2021132591A1 (enExample) 2019-12-26 2020-12-25
JP2022097020A Active JP7201192B2 (ja) 2019-12-26 2022-06-16 エクソン50のスキッピングを誘導するアンチセンス核酸

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022097020A Active JP7201192B2 (ja) 2019-12-26 2022-06-16 エクソン50のスキッピングを誘導するアンチセンス核酸

Country Status (16)

Country Link
US (2) US20230073008A1 (enExample)
EP (1) EP4083208A4 (enExample)
JP (2) JPWO2021132591A1 (enExample)
KR (1) KR20220122673A (enExample)
CN (3) CN118109468A (enExample)
AU (1) AU2020411964A1 (enExample)
BR (1) BR112022012622A2 (enExample)
CA (1) CA3165961A1 (enExample)
CO (1) CO2022008664A2 (enExample)
IL (1) IL294271A (enExample)
MX (1) MX2022007937A (enExample)
MY (1) MY209476A (enExample)
PH (1) PH12022551431A1 (enExample)
TW (2) TWI874546B (enExample)
WO (1) WO2021132591A1 (enExample)
ZA (1) ZA202206667B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2022007491A (es) * 2019-12-19 2022-08-15 Nippon Shinyaku Co Ltd Acido nucleico antisentido que permite la omision de exones.
AU2020411964A1 (en) * 2019-12-26 2022-06-16 National Center Of Neurology And Psychiatry Antisense nucleic acid that induces skipping of exon 50
AU2022424485A1 (en) 2021-12-27 2024-07-11 Nippon Shinyaku Co., Ltd. Method for producing oligonucleic acid compound
WO2023168427A1 (en) 2022-03-03 2023-09-07 Yale University Compositions and methods for delivering therapeutic polynucleotides for exon skipping

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US4235871A (en) 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4737323A (en) 1986-02-13 1988-04-12 Liposome Technology, Inc. Liposome extrusion method
DE69033986T2 (de) 1989-12-20 2003-03-13 Antivirals Inc., Portland Ungeladene, auf Morpholin basierende Polymere mit Chiralen, Phosphor enthaltenden Brücken zwischen den Untereinheiten
JP2924179B2 (ja) 1993-02-19 1999-07-26 日本新薬株式会社 グリセロール誘導体,デバイス及び医薬組成物
IL115849A0 (en) 1994-11-03 1996-01-31 Merz & Co Gmbh & Co Tangential filtration preparation of liposomal drugs and liposome product thereof
EP2530155B1 (en) 2002-11-25 2016-03-16 Masafumi Matsuo ENA nucleic acid drugs modifying splicing in mRNA precursor
SI2206781T1 (sl) 2004-06-28 2016-05-31 The University Of Western Australia Protismiselni oligonukleotidi za induciranje preskakovanja eksona in postopki njihove uporabe
ES2657400T3 (es) 2006-05-10 2018-03-05 Sarepta Therapeutics, Inc. Análogos de oligonucleótidos que tienen enlaces intersubunitarios catiónicos
AU2008271050B2 (en) 2007-06-29 2014-11-06 Sarepta Therapeutics, Inc. Tissue specific peptide conjugates and methods
CA2884340C (en) 2007-11-15 2017-07-25 Sarepta Therapeutics, Inc. Method of synthesis of morpholino oligomers
EP2762567B1 (en) * 2008-10-24 2016-07-13 Sarepta Therapeutics, Inc. Multiple exon skipping compositions for DMD
CA2741629C (en) 2008-10-27 2022-07-05 Academisch Ziekenhuis Leiden Methods and means for efficient skipping of exon 45 in duchenne muscular dystrophy pre-mrna
CN101388842B (zh) 2008-10-30 2012-04-04 华为技术有限公司 一种存储方法和装置
SMT201800579T1 (it) 2009-11-12 2019-01-11 Univ Western Australia Molecole antisenso e metodi per trattare patologie
TWI541024B (zh) 2010-09-01 2016-07-11 日本新藥股份有限公司 反義核酸
WO2012150960A1 (en) 2011-05-05 2012-11-08 Avi Biopharma, Inc. Peptide oligonucleotide conjugates
CN108611349A (zh) * 2011-12-28 2018-10-02 日本新药株式会社 反义核酸
NZ732507A (en) * 2013-03-15 2018-08-31 Sarepta Therapeutics Inc Improved compositions for treating muscular dystrophy
US10675356B2 (en) 2015-05-19 2020-06-09 Sarepta Therapeutics, Inc. Peptide oligonucleotide conjugates
WO2017024264A2 (en) 2015-08-05 2017-02-09 Eisai R&D Management Co., Ltd. Chiral reagents for preparation of homogeneous oligomers
SG10201912902TA (en) 2015-10-09 2020-02-27 Wave Life Sciences Ltd Oligonucleotide compositions and methods thereof
WO2017062835A2 (en) * 2015-10-09 2017-04-13 Sarepta Therapeutics, Inc. Compositions and methods for treating duchenne muscular dystrophy and related disorders
EP3485015A4 (en) * 2016-07-15 2020-07-29 Ionis Pharmaceuticals, Inc. COMPOUNDS AND METHODS OF MODULATION OF DYSTROPHINE TRANSCRIPT
HRP20240705T1 (hr) 2016-12-19 2024-08-30 Sarepta Therapeutics, Inc. Oligomerni konjugati koji preskaču egzon za mišićnu distrofiju
KR102646318B1 (ko) 2016-12-19 2024-03-12 사렙타 쎄러퓨틱스 인코퍼레이티드 근육 이상증에 대한 엑손 스킵핑 올리고머 결합체
KR102810425B1 (ko) 2016-12-19 2025-05-21 사렙타 쎄러퓨틱스 인코퍼레이티드 근육 이상증에 대한 엑손 스킵핑 올리고머 결합체
SG11202104960PA (en) 2018-12-13 2021-06-29 Sarepta Therapeutics Inc Exon skipping oligomer conjugates for muscular dystrophy
AU2020411964A1 (en) * 2019-12-26 2022-06-16 National Center Of Neurology And Psychiatry Antisense nucleic acid that induces skipping of exon 50

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