JP2024026077A5 - - Google Patents
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- JP2024026077A5 JP2024026077A5 JP2023192615A JP2023192615A JP2024026077A5 JP 2024026077 A5 JP2024026077 A5 JP 2024026077A5 JP 2023192615 A JP2023192615 A JP 2023192615A JP 2023192615 A JP2023192615 A JP 2023192615A JP 2024026077 A5 JP2024026077 A5 JP 2024026077A5
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025194871A JP2026048654A (ja) | 2015-08-13 | 2025-11-14 | 分子ｍｒイメージング用マンガン系キレートコンジュゲート |
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562204519P | 2015-08-13 | 2015-08-13 | |
| US62/204,519 | 2015-08-13 | ||
| US201662356732P | 2016-06-30 | 2016-06-30 | |
| US62/356,732 | 2016-06-30 | ||
| PCT/US2016/046874 WO2017027834A1 (en) | 2015-08-13 | 2016-08-12 | Manganese-based chelate conjugates for molecular mr imaging |
| JP2018506981A JP7523883B2 (ja) | 2015-08-13 | 2016-08-12 | 分子ｍｒイメージング用マンガン系キレートコンジュゲート |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018506981A Division JP7523883B2 (ja) | 2015-08-13 | 2016-08-12 | 分子ｍｒイメージング用マンガン系キレートコンジュゲート |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025194871A Division JP2026048654A (ja) | 2015-08-13 | 2025-11-14 | 分子ｍｒイメージング用マンガン系キレートコンジュゲート |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024026077A JP2024026077A (ja) | 2024-02-28 |
| JP2024026077A5 true JP2024026077A5 (enExample) | 2024-10-07 |
Family
ID=57984258
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018506981A Active JP7523883B2 (ja) | 2015-08-13 | 2016-08-12 | 分子ｍｒイメージング用マンガン系キレートコンジュゲート |
| JP2021165864A Active JP7482099B2 (ja) | 2015-08-13 | 2021-10-08 | 分子ｍｒイメージング用マンガン系キレートコンジュゲート |
| JP2023192615A Pending JP2024026077A (ja) | 2015-08-13 | 2023-11-10 | 分子ｍｒイメージング用マンガン系キレートコンジュゲート |
| JP2025194871A Pending JP2026048654A (ja) | 2015-08-13 | 2025-11-14 | 分子ｍｒイメージング用マンガン系キレートコンジュゲート |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018506981A Active JP7523883B2 (ja) | 2015-08-13 | 2016-08-12 | 分子ｍｒイメージング用マンガン系キレートコンジュゲート |
| JP2021165864A Active JP7482099B2 (ja) | 2015-08-13 | 2021-10-08 | 分子ｍｒイメージング用マンガン系キレートコンジュゲート |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025194871A Pending JP2026048654A (ja) | 2015-08-13 | 2025-11-14 | 分子ｍｒイメージング用マンガン系キレートコンジュゲート |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10835623B2 (enExample) |
| EP (1) | EP3334464B1 (enExample) |
| JP (4) | JP7523883B2 (enExample) |
| CN (3) | CN114805196A (enExample) |
| ES (1) | ES2987778T3 (enExample) |
| WO (1) | WO2017027834A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2987778T3 (es) * | 2015-08-13 | 2024-11-18 | Massachusetts Gen Hospital | Conjugados de quelatos a base de manganeso para la imagenología por resonancia magnética molecular |
| CN108888781B (zh) * | 2018-06-27 | 2021-08-06 | 华东理工大学 | 一种超分子聚电解质胶束磁共振成像造影剂的制备方法 |
| US11267832B2 (en) | 2018-10-22 | 2022-03-08 | The Board Of Regents Of The University Of Texas System | Mn(II)-based sensors to detect zinc in vivo with MRI |
| WO2020186328A1 (en) * | 2019-03-20 | 2020-09-24 | The University Of British Columbia | Chelators and methods of making and using same |
| CN112540095B (zh) * | 2019-09-20 | 2022-03-22 | 华中农业大学 | 酶促低场核磁共振免疫传感器检测食源性致病菌的方法 |
| CN114828900A (zh) * | 2019-12-17 | 2022-07-29 | 总医院公司 | 高效髓过氧化物酶可活化成像剂 |
| CN113248422B (zh) * | 2020-02-10 | 2022-07-12 | 河南工业大学 | 一种手性α-氮杂芳烃四级碳中心类化合物、其制备方法及应用 |
| WO2022108919A1 (en) * | 2020-11-17 | 2022-05-27 | The General Hospital Corporation | Probes, systems, and methods for magnetic resonance ph sensing |
| WO2022235769A1 (en) | 2021-05-04 | 2022-11-10 | Sachem, Inc. | Strong binding metal-chelating resins using macrocycle molecules |
| TW202310925A (zh) | 2021-05-04 | 2023-03-16 | 美商沙坎公司 | 強結合金屬螯合樹脂 |
| WO2024086331A1 (en) * | 2022-10-21 | 2024-04-25 | The General Hospital Corporation | Iron based mri probes |
| CN118324653A (zh) * | 2024-03-14 | 2024-07-12 | 四川大学 | 一种化合物、金属化合物及其制备方法和应用、造影剂和成像方法 |
| EP4741400A1 (en) | 2024-11-12 | 2026-05-13 | Bayer Aktiengesellschaft | Multimeric manganese contrast agents |
| CN119499407B (zh) * | 2024-11-25 | 2026-04-07 | 中国科学院精密测量科学与技术创新研究院 | 一种Fe基T7肽靶向脑胶质瘤小分子磁共振造影剂及其制备合成方法和应用 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4622420A (en) | 1980-03-18 | 1986-11-11 | The Regents Of The University Of California | Chelating agents and method |
| US4880008A (en) | 1985-05-08 | 1989-11-14 | The General Hospital Corporation | Vivo enhancement of NMR relaxivity |
| US4899755A (en) | 1985-05-08 | 1990-02-13 | The General Hospital Corporation | Hepatobiliary NMR contrast agents |
| US4889931A (en) * | 1988-09-27 | 1989-12-26 | Salutar, Inc. | Manganese (II) chelate manufacture |
| JP2772875B2 (ja) * | 1991-05-14 | 1998-07-09 | 富士写真フイルム株式会社 | ハロゲン化銀カラー写真感光材料の処理方法及び写真用漂白定着組成物 |
| JPH07508527A (ja) * | 1992-07-01 | 1995-09-21 | ビイク グルデン ロンベルク ヒェーミッシェ ファブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング | 錯体形成剤 |
| DE69502796T2 (de) * | 1994-10-20 | 1998-10-01 | Fuji Photo Film Co Ltd | Neuer Eisen-Komplex, Verfahren zu seiner Herstellung, photographische Verarbeitungslösung und photographisches Verarbeitungsverfahren unter Verwendung dieses Komplexes |
| JP3437013B2 (ja) * | 1994-10-20 | 2003-08-18 | 富士写真フイルム株式会社 | 新規な鉄錯体、その製造方法、写真用処理組成物およびその処理方法 |
| TW319763B (enExample) | 1995-02-01 | 1997-11-11 | Epix Medical Inc | |
| DE19603033A1 (de) | 1996-01-19 | 1997-07-24 | Schering Ag | Perfluoralkylhaltige Metallkomplexe, Verfahren zu deren Herstellung und ihre Verwendung in der NMR-Diagnostik |
| BR9709798A (pt) * | 1996-06-19 | 1999-08-10 | Unilever Nv | Catalisador de alvejamento e oxidacão sistema de oxidacão catalítica e composicão de alvejamento |
| AU762754B2 (en) | 1999-02-18 | 2003-07-03 | Regents Of The University Of California, The | Salicylamide-lanthanide complexes for use as luminescent markers |
| CA2371816C (en) | 1999-02-18 | 2010-04-27 | The Regents Of The University Of California | Phthalamide-lanthanide complexes for use as luminescent markers |
| DE60021545T2 (de) * | 1999-04-01 | 2006-03-02 | Unilever N.V. | Zusammensetzung und verfahren zum bleichen eines substrats |
| EP1203026A4 (en) | 1999-07-29 | 2005-03-16 | Dyax Corp | BINDING CENTERS FOR FIBRIN |
| EP1210124A2 (en) | 1999-07-29 | 2002-06-05 | Epix Medical, Inc. | Targeting multimeric imaging agents through multilocus binding |
| US6277841B1 (en) * | 2000-03-02 | 2001-08-21 | Mallinckrodt Inc. | Quinoline ligands and metal complexes for diagnosis and therapy |
| US6984373B2 (en) | 2000-12-23 | 2006-01-10 | Dyax Corp. | Fibrin binding moieties useful as imaging agents |
| US6549798B2 (en) | 2001-02-07 | 2003-04-15 | Epix Medical, Inc. | Magnetic resonance angiography data |
| TWI284539B (en) | 2001-07-30 | 2007-08-01 | Epix Pharm Inc | A method for making a magnetic resonance (MR) imaging agent, a MR imaging contrast agent, a method for altering stability of a peptide and a modified peptide |
| TWI221406B (en) | 2001-07-30 | 2004-10-01 | Epix Medical Inc | Systems and methods for targeted magnetic resonance imaging of the vascular system |
| US6869591B2 (en) | 2002-03-26 | 2005-03-22 | Barnes-Jewish Hospital | Paramagnetic particles that provide improved relaxivity |
| FR2856689A1 (fr) | 2003-06-25 | 2004-12-31 | Guerbet Sa | Composes specifiques a forte relaxivite |
| FR2890657B1 (fr) * | 2005-09-15 | 2007-11-09 | Commissariat Energie Atomique | Procede d'obtention de complexes de lanthanides hautement luminescents. |
| US8034898B2 (en) | 2005-12-29 | 2011-10-11 | Collagen Medical, LLC | Methods of collagen imaging |
| EP2111237B1 (en) | 2006-12-11 | 2015-03-18 | BRACCO IMAGING S.p.A. | Fibrin-binding peptides and conjugates thereof |
| DE112010004188T5 (de) * | 2009-10-28 | 2012-11-22 | Sumitomo Chemical Co., Ltd. | Metallkomplex mit mehrzähnigem Liganden |
| US8772446B2 (en) * | 2010-02-19 | 2014-07-08 | Nordion (Canada) Inc. | Bifunctional chelating agents |
| EP2897967B1 (en) * | 2012-09-24 | 2017-06-21 | Qi Wang | Chelates, chelating agents, conjugates derived thereof and their use |
| RS61869B1 (sr) * | 2013-01-07 | 2021-06-30 | Massachusetts Gen Hospital | Kontrastna sredstva za magnetnu rezonancu na bazi mangana |
| US20140350256A1 (en) * | 2013-05-21 | 2014-11-27 | University Of Southern Denmark | Iron and manganese complexes comprising hexadentate monocarboxylato-containing ligands and their use for the catalysis of oxidation reactions |
| US20170050989A1 (en) * | 2013-12-03 | 2017-02-23 | The General Hospital Corporation | Molecular Imaging Probes |
| AR104939A1 (es) * | 2015-06-10 | 2017-08-23 | Chemsenti Ltd | Método oxidativo para generar dióxido de cloro |
| US10233205B2 (en) * | 2015-08-07 | 2019-03-19 | Auburn University | Magnetic resonance imaging contrast agent capable of detecting hydrogen peroxide and reducing reactive oxygen species |
| ES2987778T3 (es) * | 2015-08-13 | 2024-11-18 | Massachusetts Gen Hospital | Conjugados de quelatos a base de manganeso para la imagenología por resonancia magnética molecular |
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2016
- 2016-08-12 ES ES16835998T patent/ES2987778T3/es active Active
- 2016-08-12 CN CN202210363484.0A patent/CN114805196A/zh active Pending
- 2016-08-12 CN CN201680054836.7A patent/CN108136053B/zh active Active
- 2016-08-12 EP EP16835998.2A patent/EP3334464B1/en active Active
- 2016-08-12 US US15/751,617 patent/US10835623B2/en active Active
- 2016-08-12 JP JP2018506981A patent/JP7523883B2/ja active Active
- 2016-08-12 CN CN202210364662.1A patent/CN114890941A/zh active Pending
- 2016-08-12 WO PCT/US2016/046874 patent/WO2017027834A1/en not_active Ceased
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2020
- 2020-08-11 US US16/990,368 patent/US11400171B2/en active Active
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2021
- 2021-10-08 JP JP2021165864A patent/JP7482099B2/ja active Active
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2023
- 2023-11-10 JP JP2023192615A patent/JP2024026077A/ja active Pending
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2025
- 2025-11-14 JP JP2025194871A patent/JP2026048654A/ja active Pending