JPWO2021132166A5 - - Google Patents
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- JPWO2021132166A5 JPWO2021132166A5 JP2021567445A JP2021567445A JPWO2021132166A5 JP WO2021132166 A5 JPWO2021132166 A5 JP WO2021132166A5 JP 2021567445 A JP2021567445 A JP 2021567445A JP 2021567445 A JP2021567445 A JP 2021567445A JP WO2021132166 A5 JPWO2021132166 A5 JP WO2021132166A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- seq
- compound represented
- light chain
- represented
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019231938 | 2019-12-23 | ||
| PCT/JP2020/047706 WO2021132166A1 (ja) | 2019-12-23 | 2020-12-21 | エリブリンをベースとする抗体－薬物コンジュゲートの製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2021132166A1 JPWO2021132166A1 (https=) | 2021-07-01 |
| JPWO2021132166A5 true JPWO2021132166A5 (https=) | 2024-01-04 |
Family
ID=76575922
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021567445A Pending JPWO2021132166A1 (https=) | 2019-12-23 | 2020-12-21 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230074385A1 (https=) |
| EP (1) | EP4088739A4 (https=) |
| JP (1) | JPWO2021132166A1 (https=) |
| KR (1) | KR20220120586A (https=) |
| CN (1) | CN114828895A (https=) |
| AU (1) | AU2020414996A1 (https=) |
| BR (1) | BR112022012546A2 (https=) |
| CA (1) | CA3164797A1 (https=) |
| IL (1) | IL293040B2 (https=) |
| MX (1) | MX2022007798A (https=) |
| WO (1) | WO2021132166A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3225975A1 (en) * | 2021-07-22 | 2023-01-26 | Shanghai Senhui Medicine Co., Ltd. | Drug conjugate of eribulin derivative |
| WO2023016488A1 (zh) * | 2021-08-13 | 2023-02-16 | 昆山新蕴达生物科技有限公司 | 一种基于微管抑制剂的抗体偶联药物 |
| JP2024533356A (ja) * | 2021-09-16 | 2024-09-12 | チア タイ ティエンチン ファーマシューティカル グループ カンパニー リミテッド | 抗ｈｅｒ３抗体薬物複合体及びその組成物並びに用途 |
| CN118401258A (zh) * | 2021-12-09 | 2024-07-26 | 昆山新蕴达生物科技有限公司 | 一种亲和力改善的抗体-药物偶联物、其制备方法及应用 |
| WO2023124963A1 (zh) * | 2021-12-27 | 2023-07-06 | 昆山新蕴达生物科技有限公司 | 一种可逆反应减少的抗体-药物偶联物，其制备方法及应用 |
| CN118647408A (zh) * | 2022-02-16 | 2024-09-13 | 苏州宜联生物医药有限公司 | 抗体-艾日布林或其衍生物的偶联物、其中间体、制备方法、药物组合物和用途 |
| CN118356507A (zh) * | 2023-01-17 | 2024-07-19 | 成都百利多特生物药业有限责任公司 | 一种艾日布林类药物的偶联物 |
| JP2026504859A (ja) * | 2023-01-19 | 2026-02-10 | 江▲蘇▼恒瑞医▲薬▼股▲フン▼有限公司 | エリブリン誘導体薬物複合体を含む医薬組成物 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| EP0368684B2 (en) | 1988-11-11 | 2004-09-29 | Medical Research Council | Cloning immunoglobulin variable domain sequences. |
| EP1400536A1 (en) | 1991-06-14 | 2004-03-24 | Genentech Inc. | Method for making humanized antibodies |
| US7452539B2 (en) * | 2001-12-19 | 2008-11-18 | Genentech, Inc. | Stabilizing polypeptides which have been exposed to urea |
| DK1791565T3 (en) | 2004-09-23 | 2016-08-01 | Genentech Inc | Cysteingensplejsede antibodies and conjugates |
| CN104185477B (zh) * | 2011-11-17 | 2017-05-24 | 辉瑞公司 | 细胞毒性肽及其抗体‑药物缀合物 |
| CA2914237A1 (en) * | 2013-06-20 | 2014-12-24 | Morphotek, Inc. | Methods for treatment of ovarian cancer |
| US10870706B2 (en) * | 2015-03-20 | 2020-12-22 | Pfizer Inc. | Bifunctional cytotoxic agents containing the CTI pharmacophore |
| PE20231050A1 (es) | 2016-03-02 | 2023-07-11 | Eisai Randd Man Co Ltd | Conjugados de anticuerpo y farmaco basados en eribulina y metodos para su uso |
| AR113224A1 (es) * | 2017-04-28 | 2020-02-19 | Novartis Ag | Conjugados de anticuerpo que comprenden un agonista de sting |
| CN119405832A (zh) * | 2018-06-01 | 2025-02-11 | 卫材R&D管理有限公司 | 剪接调节抗体-药物缀合物及其使用方法 |
-
2020
- 2020-12-21 EP EP20905452.7A patent/EP4088739A4/en active Pending
- 2020-12-21 BR BR112022012546A patent/BR112022012546A2/pt unknown
- 2020-12-21 AU AU2020414996A patent/AU2020414996A1/en active Pending
- 2020-12-21 MX MX2022007798A patent/MX2022007798A/es unknown
- 2020-12-21 US US17/757,825 patent/US20230074385A1/en active Pending
- 2020-12-21 CN CN202080088854.3A patent/CN114828895A/zh active Pending
- 2020-12-21 CA CA3164797A patent/CA3164797A1/en active Pending
- 2020-12-21 IL IL293040A patent/IL293040B2/en unknown
- 2020-12-21 JP JP2021567445A patent/JPWO2021132166A1/ja active Pending
- 2020-12-21 KR KR1020227022013A patent/KR20220120586A/ko active Pending
- 2020-12-21 WO PCT/JP2020/047706 patent/WO2021132166A1/ja not_active Ceased
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