JPWO2021110737A5 - - Google Patents
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- Publication number
- JPWO2021110737A5 JPWO2021110737A5 JP2022558358A JP2022558358A JPWO2021110737A5 JP WO2021110737 A5 JPWO2021110737 A5 JP WO2021110737A5 JP 2022558358 A JP2022558358 A JP 2022558358A JP 2022558358 A JP2022558358 A JP 2022558358A JP WO2021110737 A5 JPWO2021110737 A5 JP WO2021110737A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- masitinib
- acceptable salt
- pharmaceutically acceptable
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 24
- 239000002139 L01XE22 - Masitinib Substances 0.000 claims 12
- WJEOLQLKVOPQFV-UHFFFAOYSA-N masitinib Chemical compound C1CN(C)CCN1CC1=CC=C(C(=O)NC=2C=C(NC=3SC=C(N=3)C=3C=NC=CC=3)C(C)=CC=2)C=C1 WJEOLQLKVOPQFV-UHFFFAOYSA-N 0.000 claims 12
- 229960004655 masitinib Drugs 0.000 claims 12
- 150000003839 salts Chemical class 0.000 claims 11
- 239000012453 solvate Substances 0.000 claims 10
- 208000006673 asthma Diseases 0.000 claims 8
- 239000003795 chemical substances by application Substances 0.000 claims 7
- 229940124624 oral corticosteroid Drugs 0.000 claims 6
- 238000011282 treatment Methods 0.000 claims 5
- 210000004027 cell Anatomy 0.000 claims 3
- 238000004820 blood count Methods 0.000 claims 2
- 230000001186 cumulative effect Effects 0.000 claims 2
- 210000003979 eosinophil Anatomy 0.000 claims 2
- 206010061218 Inflammation Diseases 0.000 claims 1
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical group CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 claims 1
- 230000003092 anti-cytokine Effects 0.000 claims 1
- 229960000074 biopharmaceutical Drugs 0.000 claims 1
- 229940124630 bronchodilator Drugs 0.000 claims 1
- 239000000168 bronchodilator agent Substances 0.000 claims 1
- 239000003246 corticosteroid Substances 0.000 claims 1
- 229960001334 corticosteroids Drugs 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 229940125369 inhaled corticosteroids Drugs 0.000 claims 1
- 150000002617 leukotrienes Chemical class 0.000 claims 1
- 239000003607 modifier Substances 0.000 claims 1
- XOFYZVNMUHMLCC-ZPOLXVRWSA-N prednisone Chemical compound O=C1C=C[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 XOFYZVNMUHMLCC-ZPOLXVRWSA-N 0.000 claims 1
- 229960004618 prednisone Drugs 0.000 claims 1
- 238000011519 second-line treatment Methods 0.000 claims 1
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962942377P | 2019-12-02 | 2019-12-02 | |
US62/942,377 | 2019-12-02 | ||
EP19306550.5 | 2019-12-02 | ||
EP19306550.5A EP3831384A1 (fr) | 2019-12-02 | 2019-12-02 | Utilisation de masitinib pour le traitement de l'asthme éosinophile |
PCT/EP2020/084251 WO2021110737A1 (fr) | 2019-12-02 | 2020-12-02 | Utilisation de masitinib pour le traitement de l'asthme éosinophilique |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2023503723A JP2023503723A (ja) | 2023-01-31 |
JPWO2021110737A5 true JPWO2021110737A5 (fr) | 2023-12-12 |
Family
ID=68917852
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2022558358A Pending JP2023503723A (ja) | 2019-12-02 | 2020-12-02 | 好酸球性喘息の処置のためのmasitinibの使用 |
Country Status (11)
Country | Link |
---|---|
US (1) | US20230023935A1 (fr) |
EP (2) | EP3831384A1 (fr) |
JP (1) | JP2023503723A (fr) |
KR (1) | KR20220113968A (fr) |
CN (1) | CN115038446A (fr) |
AU (1) | AU2020396190A1 (fr) |
BR (1) | BR112022010524A2 (fr) |
CA (1) | CA3162956A1 (fr) |
IL (1) | IL293205A (fr) |
MX (1) | MX2022006410A (fr) |
WO (1) | WO2021110737A1 (fr) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE375342T1 (de) | 2002-08-02 | 2007-10-15 | Ab Science | 2-(3-aminoaryl)amino-4-aryl-thiazole und ihre verwendung als c-kit inhibitoren |
JP5568312B2 (ja) | 2007-02-13 | 2014-08-06 | アーべー・シオンス | キナーゼ阻害剤としての2−アミノチアゾール化合物の合成方法 |
WO2012104402A1 (fr) * | 2011-02-04 | 2012-08-09 | Ab Science | Traitement de l'asthme sévère persistant avec le masitinib |
EP2895170A4 (fr) * | 2012-09-14 | 2016-07-20 | Childrens Medical Center | Inhibition de l'asthme déclenché par une infection virale par un inhibiteur de c-kit |
-
2019
- 2019-12-02 EP EP19306550.5A patent/EP3831384A1/fr not_active Withdrawn
-
2020
- 2020-12-02 JP JP2022558358A patent/JP2023503723A/ja active Pending
- 2020-12-02 BR BR112022010524A patent/BR112022010524A2/pt not_active Application Discontinuation
- 2020-12-02 IL IL293205A patent/IL293205A/en unknown
- 2020-12-02 EP EP20816176.0A patent/EP4069230A1/fr active Pending
- 2020-12-02 MX MX2022006410A patent/MX2022006410A/es unknown
- 2020-12-02 CN CN202080095286.XA patent/CN115038446A/zh active Pending
- 2020-12-02 US US17/779,722 patent/US20230023935A1/en active Pending
- 2020-12-02 CA CA3162956A patent/CA3162956A1/fr active Pending
- 2020-12-02 AU AU2020396190A patent/AU2020396190A1/en active Pending
- 2020-12-02 KR KR1020227021484A patent/KR20220113968A/ko unknown
- 2020-12-02 WO PCT/EP2020/084251 patent/WO2021110737A1/fr unknown
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