JPWO2021081156A5 - - Google Patents

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Publication number
JPWO2021081156A5
JPWO2021081156A5 JP2022523593A JP2022523593A JPWO2021081156A5 JP WO2021081156 A5 JPWO2021081156 A5 JP WO2021081156A5 JP 2022523593 A JP2022523593 A JP 2022523593A JP 2022523593 A JP2022523593 A JP 2022523593A JP WO2021081156 A5 JPWO2021081156 A5 JP WO2021081156A5
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JP
Japan
Prior art keywords
hla
transgenic pig
polypeptide
subject
derived
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JP2022523593A
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English (en)
Japanese (ja)
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JP2022553328A5 (https=
JP2022553328A (ja
JP7685249B2 (ja
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Priority claimed from PCT/US2020/056771 external-priority patent/WO2021081156A1/en
Publication of JP2022553328A publication Critical patent/JP2022553328A/ja
Publication of JPWO2021081156A5 publication Critical patent/JPWO2021081156A5/ja
Publication of JP2022553328A5 publication Critical patent/JP2022553328A5/ja
Priority to JP2025080039A priority Critical patent/JP2025109839A/ja
Application granted granted Critical
Publication of JP7685249B2 publication Critical patent/JP7685249B2/ja
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JP2022523593A 2019-10-22 2020-10-22 トランスジェニックブタ、その作製方法と用途、およびヒト免疫系マウスの作製方法 Active JP7685249B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025080039A JP2025109839A (ja) 2019-10-22 2025-05-12 トランスジェニックブタ、その作製方法と用途、およびヒト免疫系マウスの作製方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962924228P 2019-10-22 2019-10-22
US62/924,228 2019-10-22
US201962925859P 2019-10-25 2019-10-25
US62/925,859 2019-10-25
PCT/US2020/056771 WO2021081156A1 (en) 2019-10-22 2020-10-22 Transgenic swine, methods of making and uses thereof, and methods of making human immune system mice

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025080039A Division JP2025109839A (ja) 2019-10-22 2025-05-12 トランスジェニックブタ、その作製方法と用途、およびヒト免疫系マウスの作製方法

Publications (4)

Publication Number Publication Date
JP2022553328A JP2022553328A (ja) 2022-12-22
JPWO2021081156A5 true JPWO2021081156A5 (https=) 2023-10-27
JP2022553328A5 JP2022553328A5 (https=) 2023-10-27
JP7685249B2 JP7685249B2 (ja) 2025-05-29

Family

ID=75620265

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022523593A Active JP7685249B2 (ja) 2019-10-22 2020-10-22 トランスジェニックブタ、その作製方法と用途、およびヒト免疫系マウスの作製方法
JP2025080039A Pending JP2025109839A (ja) 2019-10-22 2025-05-12 トランスジェニックブタ、その作製方法と用途、およびヒト免疫系マウスの作製方法

Family Applications After (1)

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JP2025080039A Pending JP2025109839A (ja) 2019-10-22 2025-05-12 トランスジェニックブタ、その作製方法と用途、およびヒト免疫系マウスの作製方法

Country Status (9)

Country Link
US (1) US20220279767A1 (https=)
EP (1) EP4048802A4 (https=)
JP (2) JP7685249B2 (https=)
KR (1) KR20220084296A (https=)
CN (1) CN114585744A (https=)
AU (1) AU2020370254B2 (https=)
CA (1) CA3155234A1 (https=)
IL (1) IL292406A (https=)
WO (1) WO2021081156A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10883084B2 (en) 2018-10-05 2021-01-05 Xenotherapeutics, Inc. Personalized cells, tissues, and organs for transplantation from a humanized, bespoke, designated-pathogen free, (non-human) donor and methods and products relating to same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2227584A1 (en) * 1995-08-04 1997-02-20 The General Hospital Corporation Transgenic swine and swine cells having human hla genes
US6639122B1 (en) * 2000-09-19 2003-10-28 Animal Technology Institute Taiwan Transgenic swine having HLA-D gene, swine cells thereof and xenografts therefrom
JP2014503217A (ja) * 2010-12-31 2014-02-13 ザ トラスティーズ オブ コロンビア ユニヴァーシティ イン ザ シティ オブ ニューヨーク マウスにおける自己ｔ細胞の生成
WO2012145384A1 (en) * 2011-04-20 2012-10-26 University Of Washington Through Its Center For Commercialization Beta-2 microglobulin-deficient cells
DK3590332T3 (da) * 2011-10-28 2022-05-23 Regeneron Pharma Genmodificerede mus, der eksprimerer kimære major histokompatibilitetskompleks (MHC) II-molekyler
EP3058819B1 (en) * 2013-10-18 2021-05-19 Taiho Pharmaceutical Co., Ltd. Hla class i expressing non-human animal
AU2015360502A1 (en) * 2014-12-10 2017-06-29 Regents Of The University Of Minnesota Genetically modified cells, tissues, and organs for treating disease
EP3313176A4 (en) * 2015-06-26 2019-06-26 Indiana University Research&technology Corporation TRANSGENIC PIGS WITH GENETIC MODIFICATIONS OF SLA
MX394999B (es) * 2017-09-29 2025-03-24 Regeneron Pharma Animales no humanos que comprenden un locus ttr humanizado y metodos de uso
KR20210089659A (ko) * 2018-10-05 2021-07-16 제노세라퓨틱스, 인코포레이티드 이종이식 생성물 및 방법

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