JPWO2021075478A1 - - Google Patents
Info
- Publication number
- JPWO2021075478A1 JPWO2021075478A1 JP2021552421A JP2021552421A JPWO2021075478A1 JP WO2021075478 A1 JPWO2021075478 A1 JP WO2021075478A1 JP 2021552421 A JP2021552421 A JP 2021552421A JP 2021552421 A JP2021552421 A JP 2021552421A JP WO2021075478 A1 JPWO2021075478 A1 JP WO2021075478A1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/06—Preparation
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/74—Optical detectors
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/86—Signal analysis
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/86—Signal analysis
- G01N30/8624—Detection of slopes or peaks; baseline correction
- G01N30/8631—Peaks
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/86—Signal analysis
- G01N30/8675—Evaluation, i.e. decoding of the signal into analytical information
- G01N30/8679—Target compound analysis, i.e. whereby a limited number of peaks is analysed
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N2030/022—Column chromatography characterised by the kind of separation mechanism
- G01N2030/027—Liquid chromatography
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N2030/042—Standards
- G01N2030/045—Standards internal
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/06—Preparation
- G01N2030/067—Preparation by reaction, e.g. derivatising the sample
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
- G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
- G01N2030/8818—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving amino acids
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
- G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
- G01N2030/8831—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving peptides or proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
- G01N2030/884—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample organic compounds
Landscapes
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Engineering & Computer Science (AREA)
- Library & Information Science (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2019188647 | 2019-10-15 | ||
PCT/JP2020/038852 WO2021075478A1 (ja) | 2019-10-15 | 2020-10-15 | Fmoc骨格を有する保護基で保護されたアミノ基含有化合物の定量法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPWO2021075478A1 true JPWO2021075478A1 (ja) | 2021-04-22 |
JPWO2021075478A5 JPWO2021075478A5 (ja) | 2023-10-17 |
Family
ID=75537375
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2021552421A Pending JPWO2021075478A1 (ja) | 2019-10-15 | 2020-10-15 |
Country Status (6)
Country | Link |
---|---|
US (1) | US20240151696A1 (ja) |
EP (1) | EP4046982A4 (ja) |
JP (1) | JPWO2021075478A1 (ja) |
KR (1) | KR20220082001A (ja) |
CN (1) | CN114585916A (ja) |
WO (1) | WO2021075478A1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114487164A (zh) * | 2021-12-29 | 2022-05-13 | 四川汇宇制药股份有限公司 | 保护氨基酸与其n端脱掉保护基的杂质的分离检测方法 |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115327010B (zh) * | 2022-07-25 | 2023-08-29 | 泰州兴普泰生物制药有限公司 | Fmoc-L-Pro-OH.H2O及相关杂质的含量测定方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070207555A1 (en) * | 2005-02-03 | 2007-09-06 | Cesar Guerra | Ultra-sensitive detection systems using multidimension signals |
CN100535657C (zh) * | 2006-08-24 | 2009-09-02 | 宝山钢铁股份有限公司 | 9-芴甲醇纯度的测定方法 |
JP5515738B2 (ja) * | 2007-07-25 | 2014-06-11 | 味の素株式会社 | ジベンゾフルベン誘導体の淘汰方法 |
KR100936608B1 (ko) * | 2008-01-24 | 2010-01-13 | (주)아모레퍼시픽 | 액체크로마토그래피를 이용한 두 종 이상의 아미노산동시분석 방법 |
TW201212991A (en) * | 2010-06-18 | 2012-04-01 | Centre Nat Rech Scient | Purification of amphoteric products, or of products liable to be converted into amphoteric products |
CN101893611B (zh) * | 2010-07-08 | 2013-04-24 | 天津春发生物科技集团有限公司 | 一种利用反相高效液相色谱分析游离氨基酸的方法 |
CN102621250B (zh) * | 2011-01-30 | 2014-06-11 | 复旦大学 | 一种检测多种常见氨基酸的液相色谱方法 |
EP2716650A1 (en) * | 2011-05-31 | 2014-04-09 | Ajinomoto Co., Inc. | Method for producing peptide |
WO2018225851A1 (ja) * | 2017-06-09 | 2018-12-13 | 中外製薬株式会社 | N-置換アミノ酸を含むペプチドの合成方法 |
-
2020
- 2020-10-15 EP EP20877936.3A patent/EP4046982A4/en active Pending
- 2020-10-15 CN CN202080071535.1A patent/CN114585916A/zh active Pending
- 2020-10-15 JP JP2021552421A patent/JPWO2021075478A1/ja active Pending
- 2020-10-15 KR KR1020227014363A patent/KR20220082001A/ko unknown
- 2020-10-15 US US17/769,317 patent/US20240151696A1/en active Pending
- 2020-10-15 WO PCT/JP2020/038852 patent/WO2021075478A1/ja active Application Filing
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114487164A (zh) * | 2021-12-29 | 2022-05-13 | 四川汇宇制药股份有限公司 | 保护氨基酸与其n端脱掉保护基的杂质的分离检测方法 |
CN114487164B (zh) * | 2021-12-29 | 2023-03-21 | 四川汇宇制药股份有限公司 | 保护氨基酸与其n端脱掉保护基的杂质的分离检测方法 |
Also Published As
Publication number | Publication date |
---|---|
CN114585916A (zh) | 2022-06-03 |
EP4046982A1 (en) | 2022-08-24 |
KR20220082001A (ko) | 2022-06-16 |
US20240151696A1 (en) | 2024-05-09 |
WO2021075478A1 (ja) | 2021-04-22 |
EP4046982A4 (en) | 2023-10-18 |
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