JPWO2021050656A5 - - Google Patents
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- JPWO2021050656A5 JPWO2021050656A5 JP2022515826A JP2022515826A JPWO2021050656A5 JP WO2021050656 A5 JPWO2021050656 A5 JP WO2021050656A5 JP 2022515826 A JP2022515826 A JP 2022515826A JP 2022515826 A JP2022515826 A JP 2022515826A JP WO2021050656 A5 JPWO2021050656 A5 JP WO2021050656A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
- antigen
- binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962898896P | 2019-09-11 | 2019-09-11 | |
| US62/898,896 | 2019-09-11 | ||
| US202062985808P | 2020-03-05 | 2020-03-05 | |
| US62/985,808 | 2020-03-05 | ||
| PCT/US2020/050090 WO2021050656A1 (en) | 2019-09-11 | 2020-09-10 | Compositions and methods comprising prostate stem cell antigen (psca) chimeric antigen receptors (cars) |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022547552A JP2022547552A (ja) | 2022-11-14 |
| JPWO2021050656A5 true JPWO2021050656A5 (enExample) | 2023-09-14 |
| JP7682859B2 JP7682859B2 (ja) | 2025-05-26 |
Family
ID=74849499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022515826A Active JP7682859B2 (ja) | 2019-09-11 | 2020-09-10 | 前立腺幹細胞抗原（ｐｓｃａ）キメラ抗原受容体（ｃａｒ）を含む組成物および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US11766453B2 (enExample) |
| EP (1) | EP4028414A4 (enExample) |
| JP (1) | JP7682859B2 (enExample) |
| CN (1) | CN114729059A (enExample) |
| AU (1) | AU2020347171A1 (enExample) |
| WO (1) | WO2021050656A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113698490B (zh) * | 2020-05-22 | 2024-04-30 | 重庆精准生物技术有限公司 | 靶向cea的缺氧诱导启动的car结构及免疫细胞和应用 |
| US20250152716A1 (en) * | 2022-02-18 | 2025-05-15 | The Regents Of The University Of California | Improved primary human nk cell expansion and function by chimeric cytokine receptor |
| WO2024040194A1 (en) | 2022-08-17 | 2024-02-22 | Capstan Therapeutics, Inc. | Conditioning for in vivo immune cell engineering |
| JP2026507228A (ja) | 2023-03-03 | 2026-02-27 | アーセナル バイオサイエンシズ インコーポレイテッド | Ｐｓｍａ及びｃａ９を標的とするシステム |
| WO2025179294A2 (en) | 2024-02-22 | 2025-08-28 | Capstan Therapeutics, Inc. | Immune engineering amplification |
| WO2025235801A1 (en) | 2024-05-08 | 2025-11-13 | City Of Hope | Antibodies targeted to osteopontin and uses thereof for reducing resistance of solid tumors immune cell therapy |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006089230A2 (en) * | 2005-02-18 | 2006-08-24 | Medarex, Inc. | Human monoclonal antibodies to prostate specific membrane antigen (psma) |
| WO2009032949A2 (en) * | 2007-09-04 | 2009-03-12 | The Regents Of The University Of California | High affinity anti-prostate stem cell antigen (psca) antibodies for cancer targeting and detection |
| RU2547600C2 (ru) * | 2008-10-01 | 2015-04-10 | Эмджен Рисерч (Мьюник) Гмбх | Pscaxcd3, cd19xcd3, c-metxcd3, эндосиалинxcd3, epcamxcd3, igf-1rxcd3 или fap-альфаxcd3 биспецифическое одноцепочечное антитело с межвидовой специфичностью |
| MX2014010183A (es) * | 2012-02-22 | 2015-03-20 | Univ Pennsylvania | Composiciones y metodos para generar una poblacion persistente de celulas t utiles para el tratamiento de cancer. |
| SG11201408787PA (en) * | 2012-07-13 | 2015-01-29 | Univ Pennsylvania | Enhancing activity of car t cells by co-introducing a bispecific antibody |
| AU2013329186B2 (en) * | 2012-10-10 | 2019-02-14 | Sangamo Therapeutics, Inc. | T cell modifying compounds and uses thereof |
| JP6493692B2 (ja) * | 2013-03-15 | 2019-04-10 | セルジーン コーポレイション | 修飾されたｔリンパ球 |
| JP2017513818A (ja) * | 2014-03-15 | 2017-06-01 | ノバルティス アーゲー | キメラ抗原受容体を使用する癌の処置 |
| HK1243333A1 (zh) | 2014-10-31 | 2018-07-13 | The Trustees Of The University Of Pennsylvania | 用於修饰的t细胞的方法和组合物 |
| RU2759879C2 (ru) * | 2015-10-06 | 2021-11-18 | Сити Оф Хоуп | Химерные рецепторы антигена, нацеленные на psca |
| US11485792B2 (en) | 2016-06-06 | 2022-11-01 | Polytherics Limited | Antibodies, uses thereof and conjugates thereof |
| GB201614162D0 (en) | 2016-08-18 | 2016-10-05 | Polytherics Ltd | Antibodies, uses thereof and conjugates thereof |
| CN108395480A (zh) | 2017-02-08 | 2018-08-14 | 广州百尼夫生物科技有限公司 | 嵌合抗原受体及其基因和重组表达载体、carher2-nkt细胞及其制备方法和应用 |
| CA3054104A1 (en) * | 2017-03-27 | 2018-10-04 | F. Hoffmann-La Roche Ag | Improved antigen binding receptor formats |
| US10934336B2 (en) * | 2017-04-13 | 2021-03-02 | The Trustees Of The University Of Pennsylvania | Use of gene editing to generate universal TCR re-directed T cells for adoptive immunotherapy |
| WO2019118508A1 (en) * | 2017-12-12 | 2019-06-20 | The Trustees Of The University Of Pennsylvania | Genetically modified immune cells targeting ny-eso-1 and methods of use thereof |
| CN109593726A (zh) * | 2018-12-26 | 2019-04-09 | 重庆精准生物技术有限公司 | 增强car-t细胞归巢到实体肿瘤组织能力的试剂及其应用 |
-
2020
- 2020-09-10 EP EP20863540.9A patent/EP4028414A4/en active Pending
- 2020-09-10 AU AU2020347171A patent/AU2020347171A1/en active Pending
- 2020-09-10 WO PCT/US2020/050090 patent/WO2021050656A1/en not_active Ceased
- 2020-09-10 CN CN202080078234.1A patent/CN114729059A/zh active Pending
- 2020-09-10 JP JP2022515826A patent/JP7682859B2/ja active Active
- 2020-09-10 US US17/017,238 patent/US11766453B2/en active Active
-
2023
- 2023-09-08 US US18/463,630 patent/US20240041921A1/en active Pending
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