JPWO2021032852A5 - - Google Patents

Download PDF

Info

Publication number
JPWO2021032852A5
JPWO2021032852A5 JP2022510802A JP2022510802A JPWO2021032852A5 JP WO2021032852 A5 JPWO2021032852 A5 JP WO2021032852A5 JP 2022510802 A JP2022510802 A JP 2022510802A JP 2022510802 A JP2022510802 A JP 2022510802A JP WO2021032852 A5 JPWO2021032852 A5 JP WO2021032852A5
Authority
JP
Japan
Prior art keywords
cells
population
positive
progenitor
tcr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022510802A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022545078A (ja
JP2022545078A5 (https=
Publication date
Priority claimed from GBGB1911953.6A external-priority patent/GB201911953D0/en
Application filed filed Critical
Publication of JP2022545078A publication Critical patent/JP2022545078A/ja
Publication of JP2022545078A5 publication Critical patent/JP2022545078A5/ja
Publication of JPWO2021032852A5 publication Critical patent/JPWO2021032852A5/ja
Pending legal-status Critical Current

Links

JP2022510802A 2019-08-20 2020-08-20 RAGが不活性化されたiPSCからのT細胞生産 Pending JP2022545078A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1911953.6 2019-08-20
GBGB1911953.6A GB201911953D0 (en) 2019-08-20 2019-08-20 T cell production fram RAG inacivated iPSCs
PCT/EP2020/073400 WO2021032852A1 (en) 2019-08-20 2020-08-20 T cell production from rag inactivated ipscs

Publications (3)

Publication Number Publication Date
JP2022545078A JP2022545078A (ja) 2022-10-25
JP2022545078A5 JP2022545078A5 (https=) 2023-08-18
JPWO2021032852A5 true JPWO2021032852A5 (https=) 2023-08-18

Family

ID=68099394

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022510802A Pending JP2022545078A (ja) 2019-08-20 2020-08-20 RAGが不活性化されたiPSCからのT細胞生産

Country Status (12)

Country Link
US (1) US20220275332A1 (https=)
EP (1) EP4017968A1 (https=)
JP (1) JP2022545078A (https=)
KR (1) KR20220044844A (https=)
CN (1) CN114269904A (https=)
AU (1) AU2020334258A1 (https=)
BR (1) BR112022003093A2 (https=)
CA (1) CA3150429A1 (https=)
GB (1) GB201911953D0 (https=)
IL (1) IL290604A (https=)
MX (1) MX2022001959A (https=)
WO (1) WO2021032852A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020333918A1 (en) * 2019-08-20 2022-03-24 Adaptimmune Limited Culture medium for haematopoietic induction
GB202006903D0 (en) * 2020-05-11 2020-06-24 Adaptimmune Ltd Modified iPSCs
GB202111169D0 (en) * 2021-08-03 2021-09-15 Adaptimmune Ltd Methods of T cell production
CN114517176B (zh) * 2022-01-27 2022-12-02 广东普罗凯融生物医药科技有限公司 一种将ips细胞诱导成nk细胞的试剂盒及其应用方法
GB202205572D0 (en) 2022-04-14 2022-06-01 Adaptimmune Ltd Engineered T cells
GB202208545D0 (en) 2022-06-10 2022-07-27 Adaptimmune Ltd Production of immune cells
GB202318950D0 (en) 2023-12-12 2024-01-24 Adaptimmune Ltd Production of immune cells
CN118421559B (zh) * 2024-07-04 2024-09-27 成都赛济元生物医药有限公司 定向分化淋巴造血前体细胞的小分子组合、试剂盒及方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012061075A2 (en) * 2010-10-25 2012-05-10 The Regents Of The University Of California Hiv resistant and functional hematopoietic stem/progenitor cells and macrophages from induced pluripotent stem cells
JP6677631B2 (ja) * 2013-03-13 2020-04-08 ウイスコンシン アラムナイ リサーチ ファウンデーシヨンWisconsin Alumni Research Foundation 定義された条件下におけるヒト多能性幹細胞の造血内皮分化のための方法及び材料
KR102654784B1 (ko) * 2014-07-18 2024-04-04 사이아스 가부시키가이샤 다능성 줄기세포로부터 세포-기반 면역요법용 t 세포를 유도하는 방법
WO2017075261A1 (en) * 2015-10-27 2017-05-04 Recombinetics, Inc. Engineering of humanized car t-cells and platelets by genetic complementation
CA3003152A1 (en) * 2015-11-04 2017-05-11 Fate Therapeutics, Inc. Methods and compositions for inducing hematopoietic cell differentiation
JP2019080491A (ja) * 2016-03-16 2019-05-30 国立大学法人京都大学 免疫細胞療法用ny−eso1抗原特異的t細胞の誘導方法
CN112534044A (zh) * 2018-02-16 2021-03-19 凯德药业股份有限公司 经修饰的多能干细胞及制备和使用方法
AU2020333918A1 (en) * 2019-08-20 2022-03-24 Adaptimmune Limited Culture medium for haematopoietic induction

Similar Documents

Publication Publication Date Title
JP7560502B2 (ja) 多能性幹細胞からhlaホモ接合免疫細胞への指向分化方法
US12129486B2 (en) Methods for directed differentiation of pluripotent stem cells to immune cells
JP5984217B2 (ja) 少量の末梢血からの人工多能性幹細胞の作製
JP2022163165A (ja) 抗原特異的t細胞の製造方法
JP7092281B2 (ja) 多能性幹細胞から模倣自然免疫細胞を生成する方法及びキット
US11377639B2 (en) Lineage reprogramming to induced cardiac progenitor cells (iCPC) by defined factors
JP5433879B2 (ja) 前原始線条及び中内胚葉細胞
JP2019526266A (ja) 人工多能性幹細胞由来の免疫細胞
JP2020536551A (ja) 一時的かつ一過性プラスミドベクター発現システムを用いる細胞のリプログラミング
JPWO2021032851A5 (https=)
JPWO2021032852A5 (https=)
US20250154458A1 (en) Methods for Making, Compositions Comprising, and Methods of Using Rejuvenated T Cells
JPWO2021032855A5 (https=)
CN116348592A (zh) 诱导性多能干细胞的改善的重编程、维持和保存
RU2022107097A (ru) Получение т-клеток из ipsc с инактивированным rag
JPWO2022175401A5 (https=)
JPWO2021032836A5 (https=)
US20240018200A1 (en) Compositions, constructs and vectors for cell reprogramming
AU2023338407A1 (en) Reagents and methods for producing erythromyeloid progenitor cells, nk cells, and megakaryocytes
RU2022107099A (ru) Культуральная среда для гемопоэтической индукции
KR20250158024A (ko) Hpv 특이적 세포상해성 t 세포의 t 세포 수용체 또는 그 기능적 단편
HK40092735A (zh) 诱导性多能干细胞的改善的重编程、维持和保存