JPWO2021005729A1 - - Google Patents

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Publication number
JPWO2021005729A1
JPWO2021005729A1 JP2021530411A JP2021530411A JPWO2021005729A1 JP WO2021005729 A1 JPWO2021005729 A1 JP WO2021005729A1 JP 2021530411 A JP2021530411 A JP 2021530411A JP 2021530411 A JP2021530411 A JP 2021530411A JP WO2021005729 A1 JPWO2021005729 A1 JP WO2021005729A1
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JP
Japan
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JP2021530411A
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JP7185243B2 (ja
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Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0655—Chondrocytes; Cartilage
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases (EC 2.)
    • C12N2501/727—Kinases (EC 2.7.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Data Mining & Analysis (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Public Health (AREA)
  • Software Systems (AREA)
  • Bioethics (AREA)
  • Artificial Intelligence (AREA)
  • Databases & Information Systems (AREA)
  • Evolutionary Computation (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2021530411A 2019-07-09 2019-07-09 ｉＰＳ細胞の分化効率予測モデルの構築方法及びｉＰＳ細胞の分化効率予測方法 Active JP7185243B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2019/027225 WO2021005729A1 (ja) 2019-07-09 2019-07-09 ｉＰＳ細胞の分化効率予測モデルの構築方法及びｉＰＳ細胞の分化効率予測方法

Publications (2)

Publication Number Publication Date
JPWO2021005729A1 true JPWO2021005729A1 (ja) 2021-01-14
JP7185243B2 JP7185243B2 (ja) 2022-12-07

Family

ID=74115000

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021530411A Active JP7185243B2 (ja) 2019-07-09 2019-07-09 ｉＰＳ細胞の分化効率予測モデルの構築方法及びｉＰＳ細胞の分化効率予測方法

Country Status (3)

Country Link
US (1) US20220246231A1 (ja)
JP (1) JP7185243B2 (ja)
WO (1) WO2021005729A1 (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2021145402A1 (ja) * 2020-01-16 2021-07-22

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016032470A (ja) * 2010-03-22 2016-03-10 ステミナ バイオマーカー ディスカバリー， インコーポレイテッド ヒト幹細胞様細胞及びメタボロミクスを使用した医薬のヒト発生毒性の予測
WO2016052558A1 (ja) * 2014-09-29 2016-04-07 東京エレクトロン株式会社 培養培地分析による多能性幹細胞の未分化状態の判定方法
WO2017068801A1 (ja) * 2015-10-23 2017-04-27 株式会社島津製作所 細胞の分化状態の評価方法
JP2017148046A (ja) * 2011-03-02 2017-08-31 バーグ エルエルシー 照合性細胞ベースのアッセイ及びその使用
WO2018225868A1 (ja) * 2017-06-10 2018-12-13 株式会社 島津製作所 ｉＰＳ細胞の遺伝子発現プロファイルによる軟骨細胞への分化能予測方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016032470A (ja) * 2010-03-22 2016-03-10 ステミナ バイオマーカー ディスカバリー， インコーポレイテッド ヒト幹細胞様細胞及びメタボロミクスを使用した医薬のヒト発生毒性の予測
JP2017148046A (ja) * 2011-03-02 2017-08-31 バーグ エルエルシー 照合性細胞ベースのアッセイ及びその使用
WO2016052558A1 (ja) * 2014-09-29 2016-04-07 東京エレクトロン株式会社 培養培地分析による多能性幹細胞の未分化状態の判定方法
WO2017068801A1 (ja) * 2015-10-23 2017-04-27 株式会社島津製作所 細胞の分化状態の評価方法
WO2018225868A1 (ja) * 2017-06-10 2018-12-13 株式会社 島津製作所 ｉＰＳ細胞の遺伝子発現プロファイルによる軟骨細胞への分化能予測方法

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CEZAR, GABRIELA G. ET AL., IDENTIFICATION OF SMALL MOLECULES FROM HUMAN EMBRYONIC STEM CELLS USING M, JPN6019037150, ISSN: 0004910994 *
FOLMES, CLIFFORD DL ET AL., METABOLOME AND METABOPROTEOME REMODELING IN NUCLEAR REPROGRAMMING, CELL, JPN6019037145, ISSN: 0004910992 *
STRINGARI, CHIARA ET AL., PHASOR APPROACH TO FLUORESCENCE LIFETIME MICROSCOPY DISTINGUISHES DIFFEREN, JPN6019037146, ISSN: 0004910993 *
渡辺真 他, IPS 細胞の軟骨分化能予測アルゴリズムの開発, 島津評 論, 2019.03.20, VOL. 75, NO. 3・4, PP., JPN6019037141, ISSN: 0004910995 *
遠山周吾, 網羅的代謝解析の再生医学への応用, 血管医学, 2013, VOL. 14, NO. 4, PP. 95(435)-101(441), JPN6019037143, ISSN: 0004910991 *

Also Published As

Publication number Publication date
US20220246231A1 (en) 2022-08-04
WO2021005729A1 (ja) 2021-01-14
JP7185243B2 (ja) 2022-12-07

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