JPWO2020245664A5 - - Google Patents
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- Publication number
- JPWO2020245664A5 JPWO2020245664A5 JP2021571989A JP2021571989A JPWO2020245664A5 JP WO2020245664 A5 JPWO2020245664 A5 JP WO2020245664A5 JP 2021571989 A JP2021571989 A JP 2021571989A JP 2021571989 A JP2021571989 A JP 2021571989A JP WO2020245664 A5 JPWO2020245664 A5 JP WO2020245664A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- cell
- compound
- lymphoma
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19305713 | 2019-06-04 | ||
| EP19305713.0 | 2019-06-04 | ||
| EP19306144 | 2019-09-20 | ||
| EP19306144.7 | 2019-09-20 | ||
| PCT/IB2020/000559 WO2020245664A1 (en) | 2019-06-04 | 2020-06-04 | N-(5-(6-ethoxypyrazin-2-yl)pyridin-2-yl)-4-(2-(methylsulfonamido)pyrimidin-4-yl) tetrahydro-2h-pyran-4-carboxamide derivatives and related compounds as human ctps1 inhibitors for the treatment of proliferative diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022536092A JP2022536092A (ja) | 2022-08-12 |
| JPWO2020245664A5 true JPWO2020245664A5 (fi) | 2023-06-23 |
Family
ID=71895028
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021571989A Pending JP2022536092A (ja) | 2019-06-04 | 2020-06-04 | 増殖性疾患の治療のための、ヒトｃｔｐｓ１阻害剤としてのｎ－（５－（６－エトキシピラジン－２－イル）ピリジン－２－イル）－４－（２－（メチルスルホンアミド）ピリミジン－４－イル）テトラヒドロ－２ｈ－ピラン－４－カルボキサミド誘導体及び関連化合物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20220324837A1 (fi) |
| EP (1) | EP3980411A1 (fi) |
| JP (1) | JP2022536092A (fi) |
| CN (1) | CN114008039B (fi) |
| IL (1) | IL288508A (fi) |
| WO (1) | WO2020245664A1 (fi) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11655246B2 (en) * | 2017-11-30 | 2023-05-23 | Step Pharma S.A.S. | Aminothiazole compounds as inhibitors of CTPS1 |
| US11505547B2 (en) | 2017-11-30 | 2022-11-22 | Step Pharma S.A.S. | Compounds |
| US20240109859A1 (en) * | 2021-02-01 | 2024-04-04 | University Of Southern California | Enzyme inhibitors and viral infection therapy |
| WO2023166076A1 (en) | 2022-03-01 | 2023-09-07 | Step Pharma S.A.S. | Combinations of ctps1 and bcl2 inhibitors for cancer |
| WO2023166077A1 (en) | 2022-03-01 | 2023-09-07 | Step Pharma S.A.S. | Combination of a ctps1 inhibitor and a atr inhibitor in cancer therapy |
| WO2023166080A1 (en) | 2022-03-01 | 2023-09-07 | Step Pharma S.A.S. | Combination treatments comprising a ctps1 inhibitor and a wee1 inhibitor |
| WO2023166078A1 (en) | 2022-03-01 | 2023-09-07 | Step Pharma S.A.S. | Combination treatments comprising a ctps1 inhibitor and a chek1 inhibitor |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004509874A (ja) * | 2000-09-25 | 2004-04-02 | アクテリオン ファマシューティカルズ リミテッド | 新規なアリールアルカン−スルフォンアミド類 |
| KR101353857B1 (ko) * | 2008-08-22 | 2014-01-21 | 노파르티스 아게 | Ｃｄｋ 억제제로서 피롤로피리미딘 화합물 |
| WO2012016993A1 (en) * | 2010-08-03 | 2012-02-09 | Nerviano Medical Sciences S.R.L. | Derivatives of pyrazolophenyl-benzenesulfonamide compounds and use thereof as antitumor agents |
| EP2640715A1 (en) * | 2010-11-17 | 2013-09-25 | Amgen Inc. | Quinoline derivatives as pik3 inhibitors |
| US20160051674A1 (en) * | 2013-04-18 | 2016-02-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions (ctps 1 inhibitors, e.g. norleucine) for inhibiting t cell proliferation in a subject in need thereof |
| WO2015089143A1 (en) * | 2013-12-10 | 2015-06-18 | Bristol-Myers Squibb Company | Imidazopyridazine compounds useful as modulators of il-12, il-23 and/or ifn alpha responses |
| EP3492454A1 (en) * | 2017-11-30 | 2019-06-05 | Step Pharma S.A.S. | Compounds |
| US11655246B2 (en) * | 2017-11-30 | 2023-05-23 | Step Pharma S.A.S. | Aminothiazole compounds as inhibitors of CTPS1 |
| US11505547B2 (en) | 2017-11-30 | 2022-11-22 | Step Pharma S.A.S. | Compounds |
| WO2019179652A1 (en) | 2018-03-23 | 2019-09-26 | Step Pharma S.A.S. | Aminopyrimidine derivatives as ctps1 inhibitors |
| WO2019180244A1 (en) * | 2018-03-23 | 2019-09-26 | Step Pharma S.A.S. | Aminopyrimidine derivatives as ctps1 inhibitors |
| RS64081B1 (sr) * | 2018-10-23 | 2023-04-28 | Step Pharma S A S | Derivati aminopirimidina/pirazina kao inhibitori ctps1 |
-
2020
- 2020-06-04 JP JP2021571989A patent/JP2022536092A/ja active Pending
- 2020-06-04 WO PCT/IB2020/000559 patent/WO2020245664A1/en unknown
- 2020-06-04 US US17/615,873 patent/US20220324837A1/en active Pending
- 2020-06-04 CN CN202080041337.0A patent/CN114008039B/zh active Active
- 2020-06-04 EP EP20749934.4A patent/EP3980411A1/en active Pending
-
2021
- 2021-11-29 IL IL288508A patent/IL288508A/en unknown
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