JPWO2020219775A5 - - Google Patents

Download PDF

Info

Publication number
JPWO2020219775A5
JPWO2020219775A5 JP2021563155A JP2021563155A JPWO2020219775A5 JP WO2020219775 A5 JPWO2020219775 A5 JP WO2020219775A5 JP 2021563155 A JP2021563155 A JP 2021563155A JP 2021563155 A JP2021563155 A JP 2021563155A JP WO2020219775 A5 JPWO2020219775 A5 JP WO2020219775A5
Authority
JP
Japan
Prior art keywords
antibody
seq
amino acid
antigen
variable region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021563155A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022530438A (ja
JP2022530438A5 (https=
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/029657 external-priority patent/WO2020219775A1/en
Publication of JP2022530438A publication Critical patent/JP2022530438A/ja
Publication of JPWO2020219775A5 publication Critical patent/JPWO2020219775A5/ja
Publication of JP2022530438A5 publication Critical patent/JP2022530438A5/ja
Withdrawn legal-status Critical Current

Links

Images

JP2021563155A 2019-04-24 2020-04-23 抗cd117抗体薬物複合体およびその使用 Withdrawn JP2022530438A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962838293P 2019-04-24 2019-04-24
US62/838,293 2019-04-24
PCT/US2020/029657 WO2020219775A1 (en) 2019-04-24 2020-04-23 Anti-cd117 antibody-drug conjugates and uses thereof

Publications (3)

Publication Number Publication Date
JP2022530438A JP2022530438A (ja) 2022-06-29
JPWO2020219775A5 true JPWO2020219775A5 (https=) 2023-05-01
JP2022530438A5 JP2022530438A5 (https=) 2023-05-01

Family

ID=72940987

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021563155A Withdrawn JP2022530438A (ja) 2019-04-24 2020-04-23 抗cd117抗体薬物複合体およびその使用

Country Status (4)

Country Link
US (1) US20220175944A1 (https=)
EP (1) EP3958909A4 (https=)
JP (1) JP2022530438A (https=)
WO (1) WO2020219775A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3079215A1 (en) 2017-10-24 2019-05-02 Magenta Therapeutics, Inc. Compositions and methods for the depletion of cd117+ cells
CN121555430A (zh) 2018-05-11 2026-02-24 比姆医疗股份有限公司 使用可编程碱基编辑器系统取代病原性氨基酸的方法
CN113330026A (zh) * 2018-10-23 2021-08-31 美真达治疗公司 Fc沉默的抗体药物缀合物(ADC)及其用途
CN113993550A (zh) * 2019-04-24 2022-01-28 美真达治疗公司 用于基因疗法的调理方法
EP3959242A4 (en) * 2019-04-24 2023-09-13 Magenta Therapeutics, Inc. ANTRACYCLINE ANTIBODY-DRUG CONJUGATES AND THEIR USES
WO2022132929A2 (en) * 2020-12-16 2022-06-23 Vera Therapeutics, Inc. Multispecific antibody molecules and uses thereof
WO2022187050A1 (en) * 2021-03-01 2022-09-09 BioLegend, Inc. Anti-cd117 agents and compositions and methods for making and using the same
CN117683079B (zh) * 2023-12-12 2025-04-04 九洲药业(杭州)有限公司 一种抗体偶联药物连接子的固相合成方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040006532A1 (en) * 2001-03-20 2004-01-08 David Lawrence Network access risk management
ES2882360T3 (es) * 2006-11-03 2021-12-01 Univ Leland Stanford Junior Inmunoempobrecimiento selectivo de un nicho de células madre endógenas para injerto
CN116574185A (zh) * 2012-07-25 2023-08-11 塞尔德克斯医疗公司 抗kit抗体及其用途
WO2015112822A1 (en) * 2014-01-24 2015-07-30 Kolltan Pharmaceuticals, Inc. Antibody-drug conjugates targeting kit receptor and uses thereof
HK1249534A1 (zh) * 2015-04-06 2018-11-02 哈佛大学校长及研究员协会 用於非清髓性预处理的组合物和方法
US11643668B2 (en) * 2015-06-17 2023-05-09 The Uab Research Foundation CRISPR/Cas9 complex for genomic editing
EP3370768B9 (en) * 2015-11-03 2022-03-16 Janssen Biotech, Inc. Antibodies specifically binding pd-1 and their uses
BR112018076306A2 (pt) * 2016-06-17 2019-03-26 Magenta Therapeutics, Inc. composições e métodos para a supressão de células cd117+
WO2019084067A1 (en) * 2017-10-24 2019-05-02 Magenta Therapeutics, Inc. ANTI-CD117 ANTIBODIES AND METHODS OF USE
WO2019234694A2 (en) * 2018-06-07 2019-12-12 Magenta Therapeutics, Inc. Therapeutic methods using antibody drug conjugates (adcs)
JP2022512781A (ja) * 2018-10-30 2022-02-07 マジェンタ セラピューティクス インコーポレイテッド 同種造血幹細胞移植の方法

Similar Documents

Publication Publication Date Title
JP7650819B2 (ja) 抗-cd45抗体薬物コンジュゲート及びその使用
US20260078148A1 (en) Amatoxin antibody-drug conjugates and uses thereof
JP7709376B2 (ja) Fcサイレンス化抗体薬物コンジュゲート(ADC)及びその使用
JP7669269B2 (ja) 抗-cd45抗体及びそのコンジュゲート
US20220175944A1 (en) Anti-cd117 antibody-drug conjugates and uses thereof
JPWO2020219959A5 (https=)
KR20220091567A (ko) 항-cd45 항체 및 이의 컨쥬게이트
US20220177577A1 (en) Anti-cd117 antibody drug conjugates and uses thereof
JP2022530443A5 (https=)
JP2022529726A5 (https=)
US20220226493A1 (en) Anthracycline antibody-drug conjugates and uses thereof
US20200376135A1 (en) Fc silenced antibody drug conjugates (adcs) and uses thereof
JP2025172753A (ja) 自己免疫疾患を治療するための方法および組成物
JP2022529727A5 (https=)
JPWO2020219775A5 (https=)
JPWO2021087368A5 (https=)
JPWO2020219778A5 (https=)
JPWO2020219774A5 (https=)
RU2826004C2 (ru) Аматоксиновые конъюгаты антитела с лекарственным средством и их применение