JP2022529727A5 - - Google Patents

Info

Publication number
JP2022529727A5
JP2022529727A5 JP2021562914A JP2021562914A JP2022529727A5 JP 2022529727 A5 JP2022529727 A5 JP 2022529727A5 JP 2021562914 A JP2021562914 A JP 2021562914A JP 2021562914 A JP2021562914 A JP 2021562914A JP 2022529727 A5 JP2022529727 A5 JP 2022529727A5
Authority
JP
Japan
Prior art keywords
antibody
antigen
linker
binding
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2021562914A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022529727A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/029618 external-priority patent/WO2020219748A2/en
Publication of JP2022529727A publication Critical patent/JP2022529727A/ja
Publication of JP2022529727A5 publication Critical patent/JP2022529727A5/ja
Withdrawn legal-status Critical Current

Links

JP2021562914A 2019-04-24 2020-04-23 Ａｎｔｉ－ｃｄ１１７ とその使用 Withdrawn JP2022529727A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962838255P 2019-04-24 2019-04-24
US62/838,255 2019-04-24
US201962841739P 2019-05-01 2019-05-01
US62/841,739 2019-05-01
PCT/US2020/029618 WO2020219748A2 (en) 2019-04-24 2020-04-23 Anti-cd117 antibodies and uses thereof

Publications (2)

Publication Number Publication Date
JP2022529727A JP2022529727A (ja) 2022-06-23
JP2022529727A5 true JP2022529727A5 (https=) 2022-09-20

Family

ID=72941301

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021562914A Withdrawn JP2022529727A (ja) 2019-04-24 2020-04-23 Ａｎｔｉ－ｃｄ１１７ とその使用

Country Status (4)

Country Link
US (1) US20220177578A1 (https=)
EP (1) EP3959243A4 (https=)
JP (1) JP2022529727A (https=)
WO (1) WO2020219748A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019265019B2 (en) 2018-05-11 2025-11-06 Beam Therapeutics Inc. Methods of substituting pathogenic amino acids using programmable base editor systems
WO2022187050A1 (en) * 2021-03-01 2022-09-09 BioLegend, Inc. Anti-cd117 agents and compositions and methods for making and using the same
EP4448573A1 (en) * 2021-12-16 2024-10-23 Universität Basel Discernible cell surface protein variants of cd117 for use in cell therapy

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9540443B2 (en) * 2011-01-26 2017-01-10 Kolltan Pharmaceuticals, Inc. Anti-kit antibodies
AR086044A1 (es) * 2011-05-12 2013-11-13 Imclone Llc Anticuerpos que se unen especificamente a un dominio extracelular de c-kit y usos de los mismos
ES2701051T3 (es) * 2013-03-15 2019-02-20 Novartis Ag Conjugados de anticuerpo-fármaco
WO2015050959A1 (en) * 2013-10-01 2015-04-09 Yale University Anti-kit antibodies and methods of use thereof
JP6441949B6 (ja) * 2013-11-05 2019-01-30 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル ヒト中和抗ｋｉｔ抗体及びその使用
WO2016020791A1 (en) * 2014-08-05 2016-02-11 Novartis Ag Ckit antibody drug conjugates
IL263744B2 (en) * 2016-06-17 2023-11-01 Magenta Therapeutics Inc Compositions and methods for the depletion of cd117 plus cells
WO2019084067A1 (en) * 2017-10-24 2019-05-02 Magenta Therapeutics, Inc. ANTI-CD117 ANTIBODIES AND METHODS OF USE
WO2019084057A2 (en) * 2017-10-24 2019-05-02 Magenta Therapeutics, Inc. COMPOSITIONS AND METHODS FOR DEPLOYING CD117 + CELLS
JP2021526525A (ja) * 2018-06-07 2021-10-07 マジェンタ セラピューティクス インコーポレイテッドＭａｇｅｎｔａ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． 抗体薬物コンジュゲート（ａｄｃｓ）を用いた治療方法

Similar Documents

Publication Publication Date Title
JP7641452B2 (ja) Ｃｄ１１７＋細胞を減少させるための組成物及び方法
US11572411B2 (en) Anti-CD117 antibodies and conjugates
JP7791923B2 (ja) Ｃｄ５＋細胞の枯渇のための組成物および方法
JP7669269B2 (ja) 抗－ｃｄ４５抗体及びそのコンジュゲート
JP2025160215A (ja) Ｆｃサイレンス化抗体薬物コンジュゲート（ＡＤＣ）及びその使用
TWI904109B (zh) 抗ｃｄ４５抗體及其結合物
JP2021500375A5 (https=)
US20220177575A1 (en) Anti-cd117 antibodies and uses thereof
JP2022529726A5 (https=)
CN111670200A (zh) 用于耗尽cd2+细胞的组合物和方法
JP2022530443A5 (https=)
US20220177578A1 (en) Anti-cd117 antibodies and uses thereof
JP2025172753A (ja) 自己免疫疾患を治療するための方法および組成物
JP2022529727A5 (https=)
CN112154152A (zh) 抗cd252抗体、缀合物和使用方法