JPWO2020205521A5 - - Google Patents

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Publication number
JPWO2020205521A5
JPWO2020205521A5 JP2021557927A JP2021557927A JPWO2020205521A5 JP WO2020205521 A5 JPWO2020205521 A5 JP WO2020205521A5 JP 2021557927 A JP2021557927 A JP 2021557927A JP 2021557927 A JP2021557927 A JP 2021557927A JP WO2020205521 A5 JPWO2020205521 A5 JP WO2020205521A5
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JP
Japan
Prior art keywords
cancer
pharmaceutical composition
subject
poziotinib
mutations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021557927A
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English (en)
Japanese (ja)
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JP2022527788A (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/025228 external-priority patent/WO2020205521A1/en
Publication of JP2022527788A publication Critical patent/JP2022527788A/ja
Publication of JPWO2020205521A5 publication Critical patent/JPWO2020205521A5/ja
Pending legal-status Critical Current

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JP2021557927A 2019-03-29 2020-03-27 Egfrまたはher2エクソン20挿入を有するがん細胞に対する抗腫瘍活性を有する化合物 Pending JP2022527788A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962826843P 2019-03-29 2019-03-29
US62/826,843 2019-03-29
PCT/US2020/025228 WO2020205521A1 (en) 2019-03-29 2020-03-27 Compounds with anti-tumor activity against cancer cells bearing egfr or her2 exon 20 insertions

Publications (2)

Publication Number Publication Date
JP2022527788A JP2022527788A (ja) 2022-06-06
JPWO2020205521A5 true JPWO2020205521A5 (es) 2023-04-04

Family

ID=72666976

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021557927A Pending JP2022527788A (ja) 2019-03-29 2020-03-27 Egfrまたはher2エクソン20挿入を有するがん細胞に対する抗腫瘍活性を有する化合物

Country Status (12)

Country Link
US (1) US20220143023A1 (es)
EP (1) EP3946293A4 (es)
JP (1) JP2022527788A (es)
KR (1) KR20210149103A (es)
CN (1) CN113939284A (es)
AU (1) AU2020254499A1 (es)
BR (1) BR112021019489A2 (es)
CA (1) CA3131864A1 (es)
IL (1) IL286742A (es)
MX (1) MX2021011948A (es)
SG (1) SG11202110669WA (es)
WO (1) WO2020205521A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110129434A (zh) * 2018-02-08 2019-08-16 埃提斯生物技术(上海)有限公司 胆汁中生物标志物在诊断恶性肿瘤中的应用
CA3131654A1 (en) 2019-02-26 2020-09-03 Janssen Biotech, Inc. Combination therapies and patient stratification with bispecific anti-egfr/c-met antibodies
WO2020205521A1 (en) * 2019-03-29 2020-10-08 Board Of Regents, The University Of Texas System Compounds with anti-tumor activity against cancer cells bearing egfr or her2 exon 20 insertions
WO2020214824A1 (en) * 2019-04-17 2020-10-22 Board Of Regents, The University Of Texas System Compounds against cancer bearing tyrosine kinase inhibitor resistant egfr mutations
JOP20210304A1 (ar) 2019-05-14 2023-01-30 Janssen Biotech Inc علاجات مركبة باستخدام الأجسام المضادة ثنائية النوعية المضادة لمستقبل عامل نمو البشرة (EGFR)/ مستقبل عامل نمو خلايا الكبد (c-Met) ومثبطات كيناز التيروسين الخاصة بمستقبل عامل نمو البشرة (EGFR) من الجيل الثالث
UY39593A (es) * 2020-12-29 2022-07-29 Spectrum Pharmaceuticals Inc Tratamiento para tumores sólidos malignos
CN115192580A (zh) * 2021-04-01 2022-10-18 上海医药集团股份有限公司 一种化合物在制备靶向ErbB2突变体的抑制药物中的应用
WO2023015149A1 (en) * 2021-08-02 2023-02-09 Spectrum Pharmaceuticals, Inc. Treatment of non-small cell lung cancer with poziotinib
KR20230063731A (ko) 2021-11-02 2023-05-09 주식회사 엘지에너지솔루션 전해액의 분할 주입을 포함하는 이차전지의 제조방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102627044B1 (ko) * 2015-10-19 2024-01-18 선샤인 레이크 파르마 컴퍼니 리미티드 Egfr 저해제의 염, 이의 결정질 형태 및 용도
CN110291104B (zh) * 2016-11-17 2023-11-03 得克萨斯州大学系统董事会 具有针对携带egfr或her2外显子20突变之癌细胞的抗肿瘤活性的化合物
EP3687542A1 (en) * 2017-09-27 2020-08-05 AI Therapeutics, Inc. Therapeutic methods relating to hsp90 inhibitors
KR20200132902A (ko) * 2018-03-13 2020-11-25 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 Egfr 활성화 돌연변이를 갖는 암의 치료 방법
KR20200136417A (ko) * 2018-03-27 2020-12-07 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 Her2 엑손 19 돌연변이를 보유하는 암 세포에 대해 항 종양 활성을 갖는 화합물
WO2020205521A1 (en) * 2019-03-29 2020-10-08 Board Of Regents, The University Of Texas System Compounds with anti-tumor activity against cancer cells bearing egfr or her2 exon 20 insertions

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