JPWO2020154492A5 - - Google Patents

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Publication number
JPWO2020154492A5
JPWO2020154492A5 JP2021543122A JP2021543122A JPWO2020154492A5 JP WO2020154492 A5 JPWO2020154492 A5 JP WO2020154492A5 JP 2021543122 A JP2021543122 A JP 2021543122A JP 2021543122 A JP2021543122 A JP 2021543122A JP WO2020154492 A5 JPWO2020154492 A5 JP WO2020154492A5
Authority
JP
Japan
Prior art keywords
alkyl
cycloalkyl
pharmaceutically acceptable
solvate
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021543122A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022518523A (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/014777 external-priority patent/WO2020154492A1/en
Publication of JP2022518523A publication Critical patent/JP2022518523A/ja
Publication of JPWO2020154492A5 publication Critical patent/JPWO2020154492A5/ja
Pending legal-status Critical Current

Links

JP2021543122A 2019-01-24 2020-01-23 Gpr35モジュレーター Pending JP2022518523A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962796459P 2019-01-24 2019-01-24
US62/796,459 2019-01-24
US201962873703P 2019-07-12 2019-07-12
US62/873,703 2019-07-12
US201962928223P 2019-10-30 2019-10-30
US62/928,223 2019-10-30
PCT/US2020/014777 WO2020154492A1 (en) 2019-01-24 2020-01-23 Gpr35 modulators

Publications (2)

Publication Number Publication Date
JP2022518523A JP2022518523A (ja) 2022-03-15
JPWO2020154492A5 true JPWO2020154492A5 (de) 2023-02-07

Family

ID=71733100

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021543122A Pending JP2022518523A (ja) 2019-01-24 2020-01-23 Gpr35モジュレーター

Country Status (13)

Country Link
US (2) US11053251B2 (de)
EP (1) EP3914256B1 (de)
JP (1) JP2022518523A (de)
KR (1) KR20210119485A (de)
CN (1) CN113631168A (de)
AU (1) AU2020210930A1 (de)
BR (1) BR112021014566A2 (de)
CA (1) CA3127786A1 (de)
IL (1) IL285074B1 (de)
MA (1) MA54825A (de)
MX (1) MX2021008941A (de)
TW (1) TWI845600B (de)
WO (1) WO2020154492A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI845600B (zh) 2019-01-24 2024-06-21 美商普羅米修斯生物科學股份有限公司 Gpr35調節劑
AR123034A1 (es) * 2020-07-23 2022-10-26 Prometheus Biosciences Inc Agentes terapéuticos dirigidos a gpr35
GB202303387D0 (en) * 2023-03-08 2023-04-19 Thirtyfivebio Ltd Compounds

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005119252A2 (en) * 2004-05-26 2005-12-15 Arena Pharmaceuticals, Inc. Modulators of gpr35 for the treatment of metabolic-related disorders
GB1338235A (en) * 1970-12-15 1973-11-21 May & Baker Ltd Azapurinones
GB1421970A (en) * 1973-06-12 1976-01-21 May & Baker Ltd 8-azapurin-6-one derivatives
US4052390A (en) * 1973-06-12 1977-10-04 May & Baker Limited Azapurinones
GB1561345A (en) 1976-10-22 1980-02-20 May & Baker Ltd 8 - azapuring - 6 - ones
US4923874A (en) * 1988-07-21 1990-05-08 G. D. Searle & Co. Use of 8-azapurin-6-one derivatives for control of hypertension
US5474796A (en) 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface
FR2845993B1 (fr) * 2002-10-16 2005-02-11 Univ Pasteur Composes pharmaceutiques inhibiteurs specifiques de la pde5 du muscle lisse, compositions pharmaceutiques les contenant et utilisations therapeutiques
US20070287630A1 (en) 2006-06-12 2007-12-13 Driwater, Inc. Moisturizing agent with nutrients
AU2012262021B2 (en) * 2011-06-01 2016-07-28 Janus Biotherapeutics, Inc. Novel immune system modulators
DK3030682T3 (da) 2013-08-05 2020-09-14 Twist Bioscience Corp De novo synthesized gene libraries
US20150273088A1 (en) * 2014-03-28 2015-10-01 Washington University Zaprinast analogues as glutaminase inhibitors and methods to predict response thereto
KR102658324B1 (ko) 2014-06-29 2024-04-18 프로파일 프러덕츠 엘엘씨 나무껍질 및 목재 섬유 성장 배지
US10626180B2 (en) * 2017-04-20 2020-04-21 Cedars-Sinai Medical Center Methods of treating and predicting non-response to anti-TNF treatment in subjects with inflammatory bowel disease
TW202014217A (zh) * 2018-04-27 2020-04-16 美國錫安山醫學中心 標靶gpr35以治療發炎性腸病症的組合物及方法
TWI845600B (zh) 2019-01-24 2024-06-21 美商普羅米修斯生物科學股份有限公司 Gpr35調節劑
EP3920953A4 (de) 2019-02-08 2022-12-14 Cedars-Sinai Medical Center Verfahren, systeme und kits zur behandlung von auf il18r1 abielenden entzündlichen erkrankungen
WO2020163713A1 (en) 2019-02-08 2020-08-13 Cedars-Sinai Medical Center Methods, systems, and kits for treating inflammatory disease targeting skap2
JP2022533956A (ja) 2019-05-14 2022-07-27 プロメテウス バイオサイエンシーズ,インク. Tl1a患者を選択する方法、システム、およびデバイス
EP4065727A4 (de) 2019-11-27 2024-03-27 Cedars-Sinai Medical Center Vorhersage von extraintestinalen manifestationen von entzündlicher darmerkrankung
AR123034A1 (es) 2020-07-23 2022-10-26 Prometheus Biosciences Inc Agentes terapéuticos dirigidos a gpr35
BR112023009172A2 (pt) 2020-11-13 2023-10-03 Cedars Sinai Medical Center Métodos, sistemas e kits para tratamento de doenças inflamatórias direcionados à tl1a
CA3202510A1 (en) 2020-12-21 2022-06-30 Dermot P. Mcgovern Tl1a therapy compositions and methods of treatment therewith

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