JPWO2020120979A5 - - Google Patents

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Publication number
JPWO2020120979A5
JPWO2020120979A5 JP2021534207A JP2021534207A JPWO2020120979A5 JP WO2020120979 A5 JPWO2020120979 A5 JP WO2020120979A5 JP 2021534207 A JP2021534207 A JP 2021534207A JP 2021534207 A JP2021534207 A JP 2021534207A JP WO2020120979 A5 JPWO2020120979 A5 JP WO2020120979A5
Authority
JP
Japan
Prior art keywords
peptide ligand
seq
fapα
peptide
cysteine residues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021534207A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022515721A (ja
JP2022515721A5 (https=
Publication date
Priority claimed from GBGB1820320.8A external-priority patent/GB201820320D0/en
Application filed filed Critical
Publication of JP2022515721A publication Critical patent/JP2022515721A/ja
Publication of JPWO2020120979A5 publication Critical patent/JPWO2020120979A5/ja
Publication of JP2022515721A5 publication Critical patent/JP2022515721A5/ja
Pending legal-status Critical Current

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JP2021534207A 2018-12-13 2019-12-13 FAPαに特異的な二環式ペプチドリガンド Pending JP2022515721A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1820320.8A GB201820320D0 (en) 2018-12-13 2018-12-13 Bicyclic peptide ligands specific for FAPalpha
GB1820320.8 2018-12-13
PCT/GB2019/053535 WO2020120979A1 (en) 2018-12-13 2019-12-13 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR FAPα

Publications (3)

Publication Number Publication Date
JP2022515721A JP2022515721A (ja) 2022-02-22
JPWO2020120979A5 true JPWO2020120979A5 (https=) 2022-12-19
JP2022515721A5 JP2022515721A5 (https=) 2022-12-19

Family

ID=65147028

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021534207A Pending JP2022515721A (ja) 2018-12-13 2019-12-13 FAPαに特異的な二環式ペプチドリガンド

Country Status (6)

Country Link
US (1) US20220008545A1 (https=)
EP (1) EP3894005A1 (https=)
JP (1) JP2022515721A (https=)
CN (1) CN113507961A (https=)
GB (1) GB201820320D0 (https=)
WO (1) WO2020120979A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116474108A (zh) 2016-12-14 2023-07-25 普渡研究基金会 成纤维细胞活化蛋白(fap)-靶向成像和治疗
CN111118063B (zh) * 2019-12-05 2023-04-18 吉林大学 以FAPα和survivin为基础的DNA及其在制备肿瘤疫苗中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004031374A2 (en) * 2002-09-18 2004-04-15 Prosidion Ltd. Secondary binding site of dipeptidyl peptidase iv (dp iv)
EP1452868A2 (en) 2003-02-27 2004-09-01 Pepscan Systems B.V. Method for selecting a candidate drug compound
US7374898B2 (en) * 2004-10-12 2008-05-20 The Research Foundation Of State University Of New York Peptide inhibitors against seprase
DK1844337T3 (da) 2005-01-24 2013-09-30 Pepscan Systems Bv Bindingsforbindelser, immunogene forbindelser og peptidmimetika
WO2007087131A2 (en) * 2006-01-05 2007-08-02 The Johns Hopkins University Peptide prodrugs
AU2009211253B2 (en) 2008-02-05 2014-11-06 Bicyclerd Limited Methods and compositions
CN108383893A (zh) * 2011-08-30 2018-08-10 塔夫茨大学信托人 用于治疗实体瘤的fap-活化的蛋白酶体抑制剂
JP6882978B2 (ja) 2014-10-29 2021-06-02 バイスクルアールディー・リミテッド Mt1−mmpに特異的な二環性ペプチドリガンド
WO2016146174A1 (en) * 2015-03-17 2016-09-22 Biontech Ag Compositions and methods for diagnosis and treatment of cancer
WO2018197893A1 (en) * 2017-04-27 2018-11-01 Bicycletx Limited Bicyclic peptide ligands and uses thereof

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