JPWO2020102422A5 - - Google Patents
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- Publication number
- JPWO2020102422A5 JPWO2020102422A5 JP2021525789A JP2021525789A JPWO2020102422A5 JP WO2020102422 A5 JPWO2020102422 A5 JP WO2020102422A5 JP 2021525789 A JP2021525789 A JP 2021525789A JP 2021525789 A JP2021525789 A JP 2021525789A JP WO2020102422 A5 JPWO2020102422 A5 JP WO2020102422A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
- variable domain
- chain variable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862767509P | 2018-11-14 | 2018-11-14 | |
| US62/767,509 | 2018-11-14 | ||
| US201962820718P | 2019-03-19 | 2019-03-19 | |
| US62/820,718 | 2019-03-19 | ||
| US201962886872P | 2019-08-14 | 2019-08-14 | |
| US62/886,872 | 2019-08-14 | ||
| US201962931746P | 2019-11-06 | 2019-11-06 | |
| US62/931,746 | 2019-11-06 | ||
| PCT/US2019/061278 WO2020102422A1 (en) | 2018-11-14 | 2019-11-13 | THERAPEUTIC SIRPα ANTIBODIES |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022507295A JP2022507295A (ja) | 2022-01-18 |
| JPWO2020102422A5 true JPWO2020102422A5 (https=) | 2022-11-21 |
| JP2022507295A5 JP2022507295A5 (https=) | 2022-11-21 |
Family
ID=70730617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021525789A Withdrawn JP2022507295A (ja) | 2018-11-14 | 2019-11-13 | 治療用ＳＩＲＰα抗体 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11202828B2 (https=) |
| EP (1) | EP3880239A4 (https=) |
| JP (1) | JP2022507295A (https=) |
| CN (1) | CN113573728A (https=) |
| AU (1) | AU2019380503A1 (https=) |
| BR (1) | BR112021009325A2 (https=) |
| CA (1) | CA3119748A1 (https=) |
| WO (1) | WO2020102422A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS66062B1 (sr) | 2016-04-14 | 2024-11-29 | Ose Immunotherapeutics | Nova anti-sirpa antitela i njihove terapijske primene |
| JOP20190009A1 (ar) | 2016-09-21 | 2019-01-27 | Alx Oncology Inc | أجسام مضادة ضد بروتين ألفا منظم للإشارات وطرق استخدامها |
| MX2020009774A (es) | 2018-03-21 | 2020-10-08 | Alx Oncology Inc | Anticuerpos contra proteína alfa reguladora de señal y métodos de uso. |
| CN112574310B (zh) * | 2020-12-11 | 2023-05-05 | 浙江博锐生物制药有限公司 | 抗SIRPα抗体及其用途 |
| US20240101716A1 (en) * | 2020-12-18 | 2024-03-28 | La Nova Medicines Development Co., Ltd. | BISPECIFIC ANTIBODIES TARGETING SIRPa AND PD-L1 |
| WO2022247933A1 (zh) * | 2021-05-28 | 2022-12-01 | 百奥泰生物制药股份有限公司 | 抗SIPRα抗体及其应用 |
| BR112023025194A2 (pt) * | 2021-06-04 | 2024-02-27 | Boehringer Ingelheim Int | Anticorpos anti-sirp-alfa |
| CN113956363B (zh) | 2021-10-13 | 2023-03-31 | 宜明昂科生物医药技术（上海）股份有限公司 | 靶向cd47和cd24的重组融合蛋白及其制备和用途 |
| CN117447593B (zh) * | 2022-07-26 | 2024-06-25 | 北京东方百泰生物科技股份有限公司 | 一种抗Siglec-15单克隆抗体 |
| CN115819586B (zh) * | 2022-10-13 | 2023-10-31 | 珠海市丽珠单抗生物技术有限公司 | 抗人SIRPα单克隆抗体及其用途 |
| EP4619435A1 (en) | 2022-11-16 | 2025-09-24 | Boehringer Ingelheim International GmbH | Predictive efficacy biomarkers for anti-sirpa antibodies |
| CN121358499A (zh) | 2023-03-30 | 2026-01-16 | Ose免疫疗法 | 靶向活化的免疫细胞以表达免疫细胞增强分子的基于脂质的纳米粒及其用途 |
| AU2024254671A1 (en) | 2023-03-30 | 2025-10-02 | Ose Immunotherapeutics | Method of synthesis of targeted lipid nanoparticle and uses thereof |
| WO2024220895A1 (en) * | 2023-04-20 | 2024-10-24 | Twist Bioscience Corporation | Antibodies and variant nucleic acid libraries for sirp-alpha |
| CN116514980B (zh) * | 2023-04-23 | 2025-12-16 | 杭州美赛生物医药科技有限公司 | 抗SIRPα抗体及其应用 |
| CN118047874B (zh) * | 2024-02-19 | 2025-02-18 | 中科德佑(山西)生物科技有限公司 | 一种双特异性抗体及其与t细胞在制备治疗肿瘤药物中的应用 |
| CN118791601B (zh) * | 2024-07-24 | 2025-11-14 | 苏州大学 | 一株可改善结核分枝杆菌耐药性的抗Rv0340单克隆抗体及其应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4128089A (en) * | 1988-09-15 | 1990-03-22 | Rorer International (Overseas) Inc. | Monoclonal antibodies specific to human epidermal growth factor receptor and therapeutic methods employing same |
| WO2012118547A1 (en) * | 2010-12-08 | 2012-09-07 | Stem Centrx, Inc. | Novel modulators and methods of use |
| SG2014014237A (en) * | 2011-08-17 | 2014-07-30 | Univ California | Antibodies that bind integrin alpha-v beta-8 |
| DK2780371T3 (en) * | 2011-11-16 | 2019-02-25 | Adrenomed Ag | ANTI-ADDRENOMEDULLIN (ADM) ANTIBODY OR ANTI-ADM ANTISTOFFRAGMENT OR ANTI-ADM NON-IG TEMPLATE FOR REGULATING LIQUID BALANCE OF A PATIENT WITH A CHRONIC OR ACUTE DISEASE |
| SG10201700735PA (en) | 2012-01-20 | 2017-02-27 | Genzyme Corp | Anti-cxcr3 antibodies |
| BR112018005322A2 (pt) * | 2015-09-18 | 2018-12-11 | Arch Oncology, Inc. | anticorpo monoclonal ou seu fragmento de ligação a antígenos, composição farmacêutica, anticorpo monoclonal ou seu fragmento de ligação a antígenos para uso, método de tratamento de lesão de isquemia-reperfusão, método de tratamento de câncer em um paciente humano, método de avaliação da expressão de cd47 em células tumorais e/ou imunes usando um anticorpo monoclonal ou seu fragmento de ligação a antígenos |
| SG11201808465UA (en) * | 2016-04-14 | 2018-10-30 | Ose Immunotherapeutics | NEW ANTI-SIRPa ANTIBODIES AND THEIR THERAPEUTIC APPLICATIONS |
| JOP20190009A1 (ar) * | 2016-09-21 | 2019-01-27 | Alx Oncology Inc | أجسام مضادة ضد بروتين ألفا منظم للإشارات وطرق استخدامها |
| EP3577133A1 (en) | 2017-02-06 | 2019-12-11 | Orionis Biosciences NV | Targeted chimeric proteins and uses thereof |
| CN118267470A (zh) * | 2017-04-13 | 2024-07-02 | 赛罗帕私人有限公司 | 抗SIRPα抗体 |
-
2019
- 2019-11-13 EP EP19885043.0A patent/EP3880239A4/en not_active Withdrawn
- 2019-11-13 US US16/682,893 patent/US11202828B2/en active Active
- 2019-11-13 WO PCT/US2019/061278 patent/WO2020102422A1/en not_active Ceased
- 2019-11-13 BR BR112021009325-7A patent/BR112021009325A2/pt not_active Application Discontinuation
- 2019-11-13 JP JP2021525789A patent/JP2022507295A/ja not_active Withdrawn
- 2019-11-13 CN CN201980087951.8A patent/CN113573728A/zh not_active Withdrawn
- 2019-11-13 AU AU2019380503A patent/AU2019380503A1/en not_active Withdrawn
- 2019-11-13 CA CA3119748A patent/CA3119748A1/en not_active Withdrawn
-
2021
- 2021-11-24 US US17/534,774 patent/US20220226469A1/en not_active Abandoned
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