JPWO2020093024A5 - - Google Patents

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Publication number
JPWO2020093024A5
JPWO2020093024A5 JP2021523009A JP2021523009A JPWO2020093024A5 JP WO2020093024 A5 JPWO2020093024 A5 JP WO2020093024A5 JP 2021523009 A JP2021523009 A JP 2021523009A JP 2021523009 A JP2021523009 A JP 2021523009A JP WO2020093024 A5 JPWO2020093024 A5 JP WO2020093024A5
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JP
Japan
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inventions described
inventions
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Pending
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JP2021523009A
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English (en)
Japanese (ja)
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JP2022505923A (ja
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Priority claimed from PCT/US2019/059556 external-priority patent/WO2020093024A2/en
Publication of JP2022505923A publication Critical patent/JP2022505923A/ja
Publication of JPWO2020093024A5 publication Critical patent/JPWO2020093024A5/ja
Pending legal-status Critical Current

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JP2021523009A 2018-11-01 2019-11-01 抗tim-3抗体を投与する方法 Pending JP2022505923A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862754378P 2018-11-01 2018-11-01
US62/754,378 2018-11-01
PCT/US2019/059556 WO2020093024A2 (en) 2018-11-01 2019-11-01 Methods of administering anti-tim-3 antibodies

Publications (2)

Publication Number Publication Date
JP2022505923A JP2022505923A (ja) 2022-01-14
JPWO2020093024A5 true JPWO2020093024A5 (zh) 2022-11-08

Family

ID=69159932

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021523009A Pending JP2022505923A (ja) 2018-11-01 2019-11-01 抗tim-3抗体を投与する方法

Country Status (8)

Country Link
US (1) US20220073616A1 (zh)
EP (1) EP3873612A2 (zh)
JP (1) JP2022505923A (zh)
CN (1) CN113301961A (zh)
AU (1) AU2019372436A1 (zh)
CA (1) CA3117371A1 (zh)
IL (1) IL282708A (zh)
WO (1) WO2020093024A2 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018158727A1 (en) 2017-03-02 2018-09-07 National Research Council Of Canada Tgf-β-receptor ectodomain fusion molecules and uses thereof
KR20230028795A (ko) * 2020-06-26 2023-03-02 소렌토 쎄라퓨틱스, 인코포레이티드 면역조절 융합 단백질을 발현하는 종양용해 단순헤르페스 바이러스 (hsv)
JP2024514590A (ja) * 2021-04-13 2024-04-02 メディミューン,エルエルシー Pd-1及びtim-3を標的化する二重特異性抗体
WO2022271917A1 (en) * 2021-06-24 2022-12-29 Bristol-Myers Squibb Company Transforming growth factor-beta ligand traps for the treatment of disease
CN116688115B (zh) * 2022-03-18 2024-02-06 上海齐鲁制药研究中心有限公司 一种PD-L1/TGF-β双功能融合蛋白制剂及其用途

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2269366T3 (es) 2000-02-11 2007-04-01 Merck Patent Gmbh Mejoramiento de la vida media en circulacion de proteinas de fusion basadas en anticuerpos.
CN1330664C (zh) 2001-03-07 2007-08-08 默克专利有限公司 用于含杂合同种型抗体部分的蛋白质的表达技术
US6992174B2 (en) 2001-03-30 2006-01-31 Emd Lexigen Research Center Corp. Reducing the immunogenicity of fusion proteins
WO2007145840A2 (en) * 2006-06-13 2007-12-21 Oncomed Pharmaceuticals, Inc. Compositions and methods for diagnosing and treating cancer
CA2791383C (en) 2010-03-05 2022-09-20 The Johns Hopkins University Compositions and methods for targeted immunomodulatory antibodies and fusion proteins
WO2013006490A2 (en) * 2011-07-01 2013-01-10 Cellerant Therapeutics, Inc. Antibodies that specifically bind to tim3
RS61033B1 (sr) 2011-11-28 2020-12-31 Merck Patent Gmbh Antitela na pd-l1 i njihova upotreba
JOP20200096A1 (ar) * 2014-01-31 2017-06-16 Children’S Medical Center Corp جزيئات جسم مضاد لـ tim-3 واستخداماتها
CN113549159A (zh) * 2014-02-10 2021-10-26 默克专利有限公司 靶向TGFβ抑制
EA201790173A1 (ru) * 2014-07-11 2017-06-30 Генмаб А/С Антитела, связывающие axl
BR112017007379A2 (pt) * 2014-10-14 2017-12-19 Dana Farber Cancer Inst Inc moléculas de anticorpo para pd-l1 e usos das mesmas
TWI595006B (zh) * 2014-12-09 2017-08-11 禮納特神經系統科學公司 抗pd-1抗體類和使用彼等之方法
EP3316902A1 (en) * 2015-07-29 2018-05-09 Novartis AG Combination therapies comprising antibody molecules to tim-3
CN109414500B (zh) * 2016-06-13 2022-02-25 奥美药业有限公司 治疗和诊断用pd-l1特异性单克隆抗体
CA3027495A1 (en) * 2016-06-21 2017-12-28 X4 Pharmaceuticals, Inc. Cxcr4 inhibitors and uses thereof
JOP20190013A1 (ar) * 2016-08-25 2019-01-31 Lilly Co Eli أجسام مضادة لـ (تي آي ام -3)
EP3535586A4 (en) * 2016-11-01 2020-08-05 AnaptysBio, Inc. ANTIBODIES DIRECTED AGAINST T CELL IMMUNOGUE LOBULIN AND MUCIN PROTEIN 3 (TIM-3)
EA201990743A1 (ru) * 2016-11-29 2019-11-29 Антитела, направленные против белка-3, содержащего т-клеточный иммуноглобулин и муцин (tim-3)
AU2018264455A1 (en) 2017-05-12 2019-11-14 Jiangsu Hengrui Medicine Co., Ltd. Fusion protein containing TGF-beta receptor and medicinal uses thereof

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