JPWO2020081938A5 - - Google Patents

Info

Publication number

JPWO2020081938A5

JPWO2020081938A5 JP2021521190A JP2021521190A JPWO2020081938A5 JP WO2020081938 A5 JPWO2020081938 A5 JP WO2020081938A5 JP 2021521190 A JP2021521190 A JP 2021521190A JP 2021521190 A JP2021521190 A JP 2021521190A JP WO2020081938 A5 JPWO2020081938 A5 JP WO2020081938A5

Authority

JP

Japan

Prior art keywords

alkyl

optionally substituted

compound

unsaturated

saturated

Prior art date

2022-10-25

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

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• 125000000217 alkyl group Chemical group 0.000 claims 60
• 150000001875 compounds Chemical class 0.000 claims 43
• IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 6
• 125000002947 alkylene group Chemical group 0.000 claims 5
• 239000003814 drug Substances 0.000 claims 5
• 125000004450 alkenylene group Chemical group 0.000 claims 4
• 125000004419 alkynylene group Chemical group 0.000 claims 4
• 125000000623 heterocyclic group Chemical group 0.000 claims 4
• 150000002632 lipids Chemical class 0.000 claims 4
• 239000002105 nanoparticle Substances 0.000 claims 4
• 229910052757 nitrogen Inorganic materials 0.000 claims 4
• 150000003839 salts Chemical class 0.000 claims 3
• 239000011780 sodium chloride Substances 0.000 claims 3
• 108020004999 Messenger RNA Proteins 0.000 claims 2
• 125000002704 decyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 2
• 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 2
• 229920002106 messenger RNA Polymers 0.000 claims 2
• QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims 2
• 108020004707 nucleic acids Proteins 0.000 claims 2
• 150000007523 nucleic acids Chemical class 0.000 claims 2
• 108020005544 Antisense RNA Proteins 0.000 claims 1
• -1 alkyl Compound Chemical class 0.000 claims 1
• 229920002847 antisense RNA Polymers 0.000 claims 1
• 239000003184 complementary RNA Substances 0.000 claims 1
• 238000004519 manufacturing process Methods 0.000 claims 1
• 125000002347 octyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1