JPWO2020032153A1 - Hspa8遺伝子のプロモーター - Google Patents

Hspa8遺伝子のプロモーター Download PDF

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Publication number
JPWO2020032153A1
JPWO2020032153A1 JP2020535864A JP2020535864A JPWO2020032153A1 JP WO2020032153 A1 JPWO2020032153 A1 JP WO2020032153A1 JP 2020535864 A JP2020535864 A JP 2020535864A JP 2020535864 A JP2020535864 A JP 2020535864A JP WO2020032153 A1 JPWO2020032153 A1 JP WO2020032153A1
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Prior art keywords
nucleotide sequence
promoter
hspa8
seq
polynucleotide
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JP2020535864A
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Japanese (ja)
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JPWO2020032153A5 (https=
Inventor
兼治 増田
兼治 増田
祐人 中澤
祐人 中澤
渡辺 和彦
和彦 渡辺
真初 西尾
真初 西尾
武 奥村
武 奥村
浩一 野中
浩一 野中
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Daiichi Sankyo Co Ltd
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Daiichi Sankyo Co Ltd
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Publication of JPWO2020032153A1 publication Critical patent/JPWO2020032153A1/ja
Publication of JPWO2020032153A5 publication Critical patent/JPWO2020032153A5/ja
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/02Cells for production
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription

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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
JP2020535864A 2018-08-09 2019-08-08 Hspa8遺伝子のプロモーター Pending JPWO2020032153A1 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2018149854 2018-08-09
JP2018149854 2018-08-09
PCT/JP2019/031295 WO2020032153A1 (ja) 2018-08-09 2019-08-08 Hspa8遺伝子のプロモーター

Publications (2)

Publication Number Publication Date
JPWO2020032153A1 true JPWO2020032153A1 (ja) 2021-08-12
JPWO2020032153A5 JPWO2020032153A5 (https=) 2022-06-14

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Family Applications (1)

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JP2020535864A Pending JPWO2020032153A1 (ja) 2018-08-09 2019-08-08 Hspa8遺伝子のプロモーター

Country Status (10)

Country Link
US (1) US20210317498A1 (https=)
EP (1) EP3835423A4 (https=)
JP (1) JPWO2020032153A1 (https=)
KR (1) KR20210042084A (https=)
CN (1) CN112639098A (https=)
AU (1) AU2019318910A1 (https=)
CA (1) CA3109101A1 (https=)
SG (1) SG11202100996TA (https=)
TW (1) TW202020160A (https=)
WO (1) WO2020032153A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202146432A (zh) * 2020-04-03 2021-12-16 日商第一三共股份有限公司 新基因表現單元
WO2023210607A1 (ja) 2022-04-26 2023-11-02 第一三共株式会社 Eno1遺伝子のプロモーター

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030207832A1 (en) * 1997-11-03 2003-11-06 The Arizona Board Of Regents Inducible expression vectors and methods of use thereof
WO2013080934A1 (ja) * 2011-11-28 2013-06-06 第一三共株式会社 ヒト遺伝子由来プロモーター
CN105018528A (zh) * 2015-08-20 2015-11-04 重庆大学 热休克蛋白基因启动子和四环素基因启动子控制的多基因表达和沉默系统
JP2018038388A (ja) * 2013-08-05 2018-03-15 イマティクス バイオテクノロジーズ ゲーエムベーハー Nsclcをはじめとする肺がんなどの数種の腫瘍に対する新規免疫療法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3051411U (ja) 1997-04-25 1998-08-25 信一 朝長 安全プラグ
GB0509965D0 (en) 2005-05-17 2005-06-22 Ml Lab Plc Improved expression elements
EP3093351B1 (en) * 2008-07-09 2018-04-18 Celera Corporation Genetic polymorphisms associated with cardiovascular diseases, methods of detection and uses thereof
CA2817256A1 (en) * 2010-11-12 2012-05-18 The General Hospital Corporation Polycomb-associated non-coding rnas
SG11201902998SA (en) 2016-10-03 2019-05-30 Daiichi Sankyo Co Ltd PROMOTER OF Hspa5 GENE

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030207832A1 (en) * 1997-11-03 2003-11-06 The Arizona Board Of Regents Inducible expression vectors and methods of use thereof
WO2013080934A1 (ja) * 2011-11-28 2013-06-06 第一三共株式会社 ヒト遺伝子由来プロモーター
JP2018038388A (ja) * 2013-08-05 2018-03-15 イマティクス バイオテクノロジーズ ゲーエムベーハー Nsclcをはじめとする肺がんなどの数種の腫瘍に対する新規免疫療法
CN105018528A (zh) * 2015-08-20 2015-11-04 重庆大学 热休克蛋白基因启动子和四环素基因启动子控制的多基因表达和沉默系统

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CHEN, MING-SHUN, ET AL., CELL STRESS AND CHAPERONES, vol. 1, JPN6019038602, 1996, pages 47 - 61, ISSN: 0005203910 *
CHUANG, KUO-HUNG, ET AL., GENE, vol. 405, JPN6019038613, 2007, pages 10 - 18, ISSN: 0005203913 *
LEE, JAE M, ET AL., JOURNAL OF BIOTECHNOLOGY, vol. 133, JPN6019038604, 2008, pages 9 - 17, ISSN: 0005203911 *
RUBENSTEIN, RONALD C., ET AL., AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, vol. 281, JPN6023021481, 2001, pages 43 - 51, ISSN: 0005203909 *
WU, CHIH-LU, ET AL., TRANSGENIC RESEARCH, vol. 20, JPN6019038609, 2011, pages 1217 - 1226, ISSN: 0005203912 *

Also Published As

Publication number Publication date
KR20210042084A (ko) 2021-04-16
EP3835423A4 (en) 2022-08-10
CN112639098A (zh) 2021-04-09
EP3835423A1 (en) 2021-06-16
TW202020160A (zh) 2020-06-01
US20210317498A1 (en) 2021-10-14
WO2020032153A1 (ja) 2020-02-13
CA3109101A1 (en) 2020-02-13
SG11202100996TA (en) 2021-03-30
AU2019318910A1 (en) 2021-02-18

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