JPWO2020027329A1 - Water floating pesticide preparation - Google Patents

Abstract

An object of the present invention is to provide a water-floating pesticide preparation which exhibits good floating property and diffusivity in flooding treatment under shallow water conditions and maintains its performance even after long-term storage. ) Agricultural chemical active ingredient, b) Floating carrier, c) One or more selected from Na alkylnaphthalene sulfonate and Na dialkyl succinate sulfonate, d) Major axis / minor axis ratio of the bottom surface of the grain is 1.1 ~ 1.4, e) Provided is a water-floating pesticide preparation characterized in that the particle size is 80% by weight or more in the range of 2.80 mm to 1.70 mm, and f) the number of grains per 1 g is 50 to 150.

Description

The present invention is excellent in diffusivity and storage stability, which exhibits good floating property and diffusivity in paddy field treatment, especially in flooding treatment under shallow water conditions, and maintains its performance even after long-term storage. It relates to a water-floating pesticide preparation.

As the dosage form of the pesticide preparation for paddy rice, granules, powders, wettable powders, tablets, packs, flowable agents, water solvents, liquid agents, emulsions and the like are known. In recent years, as a labor-saving method for spraying pesticides, pesticide preparations (jumbo agents, flowable agents for flooding undiluted solution, etc.) that can be sprayed simply by throwing them from the ridge without entering the paddy field have been developed and used. However, since such pesticide preparations locally spray the pesticide active ingredient in a high concentration state, it takes a long time for the pesticide active ingredient to diffuse uniformly into the rice field water, and the pesticide active ingredient is locally dispersed. The phytotoxicity of paddy rice or lack of effect due to uneven distribution has become a problem. As a means for solving these problems, it is required that the pesticide active ingredient is quickly and uniformly dispersed after the pesticide preparation is put into a paddy field under flooding.

Various methods have been proposed in response to the above requirements, and examples thereof include the following patent documents.

According to International Publication No. 2016-129466 (Patent Document 1), a pesticide active ingredient, a surfactant, a hollow body, and a solid carrier are contained, and those having a particle size of 3 mm or more have a particle size of 80% or more. A method for producing a granular pesticide composition, which has a distribution and a property of floating on the water surface and is characterized by disintegrating on the water surface within 30 minutes. A step of kneading a mixture containing a part of the activator, a part of the hollow body, a part of the solid carrier, and water; (b) The kneaded product obtained in the step (a) above. A step of granulating using an extrusion granulator; (c) a step of drying the granulated product obtained in the step (b) to obtain granules; (d) a step of (d) the step (c) above. Steps to crush the obtained granules; (e) The crushed product obtained in the step (d) above, the rest of the pesticide active ingredient, the rest of the surfactant, the rest of the hollow body, and the solid. A step of kneading a mixture containing the balance of the carrier and water; (f) The kneaded product obtained in the step (e) above is discharged from a screen having a pore size of 3 mm or more using an extrusion granulator. It is characterized by including a step of granulating; (g) a step of drying the granulated product obtained in the step (f) above. Granular pesticide compositions have been proposed.

In the International Publication No. 2016-114200 pamphlet (Patent Document 2), one or more pesticide active ingredients, water-soluble polysaccharides having water retention and suppressed swelling in water, surfactants, and surfactants are described. 80% of those having a particle size of 3 mm or more are obtained by extruding and granulating a water-containing mixture containing a hollow body, a solid carrier, and water, and then drying to remove water. A pesticide granular composition having the above particle size distribution and the property of floating on the water surface and disintegrating on the water surface within 30 minutes and a method for producing the pesticide granular composition, in a large water surface floating granular pesticide composition containing a water-containing raw material. , A large granular pesticide composition floating on the water surface with good quality and a method for producing the same have been proposed.

According to International Publication No. 2015-159906 (Patent Document 3), a pesticide active ingredient, a floating carrier and water in the range of 0.3 to 3% by mass are contained, and those having a particle size of 3 mm or more have a particle size distribution of 80% or more. , The property of floating on the water surface and the large granular pesticide preparation floating on the water surface that collapses on the water surface within 30 minutes of being put into water. For a total of n kinds of raw materials, a water surface floating large granular pesticide preparation having a value X defined by the formula (1) in the range of 0.5 to 2 and a method for producing the same have been proposed.

In Japanese Patent Application Laid-Open No. 2012-116788 (Patent Document 4), (a) bactericidal active ingredient and / or insecticidal active ingredient, (b) specific polyoxyethylene alkyl ether, (c) specific sodium alkylnaphthalene sulfonate, ( d) A water-floating pesticide preparation in which isoparaffin having a distillation point of 277 ° C. to 353 ° C. and (e) a water-floating hollow body are used in combination has been proposed.

In Japanese Patent Application Laid-Open No. 2012-116787 (Patent Document 5), (a) herbicidal active ingredient, (b) specific polyoxyethylene alkyl ether represented by the general formula (1), and (c) specific alkylnaphthalene sulfonic acid. A water-floating herbicidal preparation using sodium, (d) isoparaffin having a distillation point of 277 ° C. to 353 ° C., and (e) water-floating hollow body in combination has been proposed.

According to International Publication No. 2005-29956 (Patent Document 6), non-disintegrating pesticide granules and surfactants containing acidic pesticide active ingredients, cationic surfactants and basic substances that do not disintegrate in water within 30 minutes. It has a particle size distribution in which the mass ratio of particles having a particle size of 3 mm or more is 80% by mass or more, and has the property of floating on the water surface immediately after being dropped on the water surface, but it collapses on the water surface within 30 minutes. A uniform diffusible granular pesticide preparation has been proposed.

According to Japanese Patent Application Laid-Open No. 2002-179507 (Patent Document 7), it contains a pesticide active ingredient, has a particle size distribution of 80% of those having a particle size of 3 mm or more, and has the property of floating on the water surface, and has the property of floating on the water surface within 30 minutes. Uniformly diffusive granular pesticide formulation that disintegrates in Agricultural chemicals have been proposed.

Japanese Unexamined Patent Publication No. 2002-128605 (Patent Document 8) proposes a pesticide preparation for water surface application, which comprises using a pesticide active ingredient, a floating hollow body, and a specific polyoxyalkylene alkyl ether phosphoric acid ester or a salt thereof. ing.

In Japanese Patent Application Laid-Open No. 2000-351701 (Patent Document 9), a water surface containing one or more water surface spreading agents and pesticide active ingredients consisting of C2-C4 alkylene oxide adducts of C4-C10 alkyl alcohols and derivatives thereof. Floating pesticide solid formulations have been proposed.

In Japanese Patent Application Laid-Open No. 2001-114603 (Patent Document 10), inorganic salts, organic salts, and organic acids having a particle size of 1/10 to 1/2 with respect to the minor axis of the pesticide active ingredient and the pesticide solid composition. A pesticide solid composition containing one or more water-soluble substances selected from saccharides and urea has been proposed.

According to Japanese Patent Application Laid-Open No. 2000-319103 (Patent Document 11), a pesticide active ingredient, a surfactant, a solid carrier, a water surface suspending agent and water are contained, and the water content after molding is a water surface floating granular pesticide preparation. A water-floating granular pesticide preparation characterized by 0.3 to 6 parts per 100 parts by weight and a method for producing the same have been proposed.

In Japanese Patent Application Laid-Open No. 2000-319102 (Patent Document 12), a water-floating granular pesticide containing a pesticide active ingredient, a surfactant, a solid carrier and a water-floating granular pesticide is used as a disintegration time of the water-floating granular pesticide. A water-based pesticide preparation, which is packaged in a water-soluble film bag having a dissolution time of 1/5 or less of that of the above, has been proposed.

Japanese Patent Application Laid-Open No. 2000-302602 (Patent Document 13) contains an active pesticide ingredient, a surfactant, a solid carrier, a water surface suspending agent, water, and other auxiliary agents as necessary, and (1) per grain. Weight is 0.03g to 0.3g, and the density of one grain is 0.4 or more and less than 1.0. (3) A water-floating granular pesticide preparation and a method for producing the same have been proposed, which are characterized in that it takes less than 30 minutes for the particles floating on the water surface to disintegrate and disperse.

In Japanese Patent Application Laid-Open No. 11-310503 (Patent Document 14), a pesticide powder preparation or granule which has a property of floating on the water surface and spreading and does not contain a foaming agent is packaged in a water-soluble film having holes. Therefore, a pesticide pack for paddy field throwing that prevents solidification over time has been proposed.

Both prior arts have improved diffusivity, which is diffusivity under conditions where the water depth (amount of water) is guaranteed. On the other hand, there are some fields that can only maintain a shallow water depth (less than 3 cm) due to water leakage or natural water reduction. Under such conditions, the distance between the water surface and the soil is short. There is a risk of insufficient effect. Further, the shallow water depth is synonymous with a small amount of water, and in a formulation in which the active ingredient diffuses through the water surface and water, the diffusible range is limited as compared with the normal water depth (about 5 cm). In such fields, better floating and diffusivity are required, and it cannot be said that the prior art is sufficient. Further, regarding maintaining these performances even after long-term storage, there is no mention in the prior art, and a preparation having excellent floating property, diffusibility and storage stability is required.

International Publication No. 2016/12946 Pamphlet International Publication No. 2016/11200 Pamphlet International Publication No. 2015/159906 Pamphlet Japanese Unexamined Patent Publication No. 2012-116788 Japanese Unexamined Patent Publication No. 2012-116787 International Publication No. 2005/29956 Pamphlet JP-A-2002-179507 JP-A-2002-128605 Japanese Unexamined Patent Publication No. 2000-351701 Japanese Unexamined Patent Publication No. 2001-114603 Japanese Unexamined Patent Publication No. 2000-319103 Japanese Unexamined Patent Publication No. 2000-319102 Japanese Unexamined Patent Publication No. 2000-30602 Japanese Unexamined Patent Publication No. 11-310503

In view of the above-mentioned conventional drawbacks, the present invention has excellent floating pesticide preparation on the water surface, more specifically, excellent floating property of the pesticide preparation in the flooding treatment under shallow water conditions, and at the time of spraying. The formulation diffuses on the surface of the water without settling under the surface of the water, and the formulation exhibits excellent diffusivity in water even after disintegrating in water over time, and its performance is maintained even after long-term storage. The purpose is to provide a water-floating pesticide preparation.

The present inventors have diligently studied to solve the above problems. As a result, it is composed of one or more selected from the pesticide active ingredient, the floating carrier, and Na alkylnaphthalene sulfonate and Na dialkyl succinate sulfonate as the anionic surfactant, and the major axis / minor axis ratio of the bottom surface of the grain is increased. A water-floating pesticide preparation characterized by having a particle size of 80% by weight or more in the range of 2.80 mm to 1.70 mm and a number of grains per gram of 50 to 150 has been achieved. Found to do.
Further, as a pesticide active ingredient, a floating carrier, and an anionic surfactant, a polyoxyalkylene alkyl ether phosphoric acid ester salt is contained together with a water-soluble alkylene glycol such as propylene glycol, and as an anionic surfactant. Furthermore, it has been found that a water-floating pesticide preparation containing at least one selected from Na alkylnaphthalene sulfonate and Na dialkylsuccinate sulfonate is excellent in diffusivity. The major axis / minor axis ratio of the bottom surface of the granules of this formulation is 1.1 to 1.6, and the particle size is 80% by weight or more in the range of 2.80 mm to 1.70 mm, and the number of grains per gram is 50 to 200. It was found that the diffusivity of the water-floating pesticide preparation was particularly excellent.
Furthermore, in the above-mentioned water-floating pesticide preparation, 90% by weight or more of the particle size is in the range of 2.80 mm to 1.70 mm, the floating carrier is a silas balloon having an average particle size of 90 to 120 μm, and anionic surface activity. When the agent further contains alkylnaphthalene sulfonic acid formaldehyde condensate Na, naphthalene sulfonic acid formaldehyde condensate Na, and partially desulfonated lignin sulfonate Na (polyoxyalkylene alkyl ether phosphate ester salt and water-soluble alkylene glycol) , Na lignin sulfonate), and when carboxymethyl cellulose Na (polyoxyalkylene alkyl ether phosphoric acid ester salt and water-soluble alkylene glycol) is contained as a binder, carboxymethyl cellulose Na and polyvinyl It has been found that it is more preferable to contain (one or more kinds selected from alcohols), and the present invention has been completed.

[式中、Ｒは、炭素数８〜１０の直鎖状または分岐鎖状のアルキル基を示し、Ａは炭素数２〜４のアルキレン基を示し、ｎは１〜２０の整数を示し、ｐおよびｑは、ｐ＋ｑ＝３かつｐ＝１または２である整数を示し、Ｍは水素原子、アルカリ金属原子、アンモニウム基、または有機アンモニウム基を示す。なお、Ｒ、Ａ、Ｍがそれぞれ複数ある場合は、それらの種類は同じでも異なってもよい。]
［７］水溶性アルキレングリコールがプロピレングリコールである［６］に記載の水面浮遊性農薬製剤。
［８］以下の特徴を有する、［６］または［７］に記載の水面浮遊性農薬製剤：
ｅ）粒の底面の長径/短径比が１．１〜１．６、
ｆ）粒度が２．８０ｍｍ〜１．７０ｍｍの範囲に８０重量％以上、および
ｇ）１gあたりの粒数が５０〜２００。
［９］ｆ）前記粒度が２．８０ｍｍ〜１．７０ｍｍの範囲に９０重量％以上であることを特徴とする［８］に記載の水面浮遊性農薬製剤。
［１０］前記浮遊性担体としての中空体が平均粒子径９０〜１２０μｍのシラスバルーンであることを特徴とする［６］〜［９］のいずれかに記載の水面浮遊性農薬製剤。
［１１］更に、陰イオン性界面活性剤としてアルキルナフタレンスルホン酸ホルムアルデヒド縮合物Ｎａ、ナフタレンスルホン酸ホルムアルデヒド縮合物Ｎａ、およびリグニンスルホン酸Ｎａから選ばれる１種以上を含有することを特徴とする［６］〜［１０］のいずれかに記載の水面浮遊性農薬製剤。
［１２］更に、結合剤としてカルボキシメチルセルロースＮａおよびポリビニルアルコールから選ばれる１種以上を含有することを特徴とする［６］〜［１１］のいずれかに記載の水面浮遊性農薬製剤。That is, the gist of the present invention is as follows.
[1] A water surface containing a) a pesticide active ingredient, b) a hollow body as a floating carrier, and c) one or more selected from Na alkylnaphthalene sulfonate and Na dialkyl succinate sulfonate as an anionic surfactant. Floating pesticide preparation, which has the following characteristics:
d) The major axis / minor axis ratio of the bottom surface of the grain is 1.1 to 1.4,
e) The particle size is in the range of 2.80 mm to 1.70 mm, 80% by weight or more, and f) the number of grains per 1 g is 50 to 150.
[2] e) The water-floating pesticide preparation according to [1], wherein the particle size is 90% by weight or more in the range of 2.80 mm to 1.70 mm.
[3] The water-floating pesticide preparation according to any one of [1] and [2], wherein the hollow body as the floating carrier is a shirasu balloon having an average particle size of 90 to 120 μm.
[4] Further, it is characterized by containing at least one selected from alkylnaphthalene sulfonic acid formaldehyde condensate Na, naphthalene sulfonic acid formaldehyde condensate Na, and partially desulfonated lignin sulfonate Na as an anionic surfactant. The water-floating pesticide preparation according to any one of [1] to [3].
[5] The water-floating pesticide preparation according to any one of [1] to [4], which further contains carboxymethyl cellulose Na as a binder.
[6] a) Agricultural chemical active ingredient, b) Hollow body as a floating carrier, c) Polyoxyalkylene alkyl ether phosphoric acid ester salt represented by the following general formula (I) and water-soluble alkylene glycol, and d) Yin A water-floating pesticide preparation containing at least one selected from Na alkylnaphthalene sulfonate and Na dialkyl succinate sulfonate as an ionic surfactant.

[In the formula, R represents a linear or branched alkyl group having 8 to 10 carbon atoms, A represents an alkylene group having 2 to 4 carbon atoms, n represents an integer of 1 to 20, and p. And q represent integers p + q = 3 and p = 1 or 2, and M represents a hydrogen atom, an alkali metal atom, an ammonium group, or an organic ammonium group. When there are a plurality of R, A, and M, the types may be the same or different. ]
[7] The water-floating pesticide preparation according to [6], wherein the water-soluble alkylene glycol is propylene glycol.
[8] The water-floating pesticide preparation according to [6] or [7], which has the following characteristics:
e) The major axis / minor axis ratio of the bottom surface of the grain is 1.1 to 1.6,
f) 80% by weight or more in the range of particle size of 2.80 mm to 1.70 mm, and g) 50 to 200 grains per 1 g.
[9] f) The water-floating pesticide preparation according to [8], wherein the particle size is 90% by weight or more in the range of 2.80 mm to 1.70 mm.
[10] The water-floating pesticide preparation according to any one of [6] to [9], wherein the hollow body as the floating carrier is a shirasu balloon having an average particle diameter of 90 to 120 μm.
[11] Further, it is characterized by containing at least one selected from alkylnaphthalene sulfonic acid formaldehyde condensate Na, naphthalene sulfonic acid formaldehyde condensate Na, and lignin sulfonate Na as an anionic surfactant [6]. ] To [10]. The water-floating pesticide preparation according to any one of [10].
[12] The water-floating pesticide preparation according to any one of [6] to [11], which further contains one or more selected from carboxymethyl cellulose Na and polyvinyl alcohol as a binder.

Since the water-floating pesticide formulation of the present invention has good floating property and diffusivity, it is excellent in water surface movement of the formulation itself and diffusibility after the formulation collapses even in a flooded paddy field under shallow water conditions of less than 3 cm in depth. The performance can be maintained even after long-term storage. Therefore, a spraying machine such as a power sprayer or a spraying tool such as a granulator is not always required at the time of spraying, and hand-spraying is also possible. In addition, since it diffuses even when sprayed from one side of the ridge, the usage scene is not limited. Furthermore, since quality deterioration is suppressed even after long-term storage, it is possible to store it as a stockpile in advance. Therefore, the water-floating pesticide preparation of the present invention is a labor-saving preparation with reduced physical, time, and financial burden on the sprayer.

The water-floating pesticide preparation of the present invention will be described in more detail below.

<A. About composition ingredients>
The pesticide active ingredient that can be used in the present invention may be applicable to paddy rice, and examples of such pesticide active ingredient include the following.

《Insecticidal active ingredient》
For example, organic phosphorus (MEP, diazinone, etc.), carbamate (BPMC, carbosulfan, etc.), pyrethroid (cycloprothrin, etc.), nelystoxin (thiocyclum, etc.), neonicotinoid (thiocyclum, etc.) and neonicotinoid (thiocyclum, etc.) as insecticidal active ingredients. Imidacloprid, thiamethoxam, clothianidin, dinotefuran, etc.), diamide-based (flubendiamide, chloranthraniliprole, cyantraniliprole, etc.), phenylpyrazole-based (fipronil, etiprol, etc.), spinosin-based (spinosad, spinnetram, etc.) insecticides , Insect growth regulators (tebufenozide, chromafenozide, methoxyphenozide, buprofezin, etc.), and other synthetic insecticides (pyrethroidin, triflumezopyrim, etc.) biopesticides.

《Bactericidal active ingredient》
Examples of bactericidal active ingredients include inorganic coppers, organic coppers, inorganic sulfur agents, organic sulfur agents, organic phosphorus-based agents (IBP, etc.), and melanin biosynthesis inhibitors (pyrothyron, tricyclazole, carpropamide, diclosimet, phenoxanyl, etc.). , Benzimidazoles (benomyl, thiophanate-methyl, dietofencarb, etc.), amides (mepronil, flutranyl, flametopil, penflufen, fluxapyroxad, thyfluzamide, thiazinyl, isothianol, etc.), sterol biosynthesis inhibitors (pefrazoate, ipconazole, simeconazole, etc.) , Strobilurin (azoxistrovine, metminostrobin, orysustrobin, etc.), antibiotic fungicides (casgamycin, benomyl, etc.), other synthetic fungicides, biopesticides, etc.

<< Weeding active ingredient >>
Examples of herbicidal active ingredients include phenoxyic acid type (MCPA thioethyl, MCPB ethyl, etc.), carbamate type, acid amide type (tenylchlor, butacrol, bromobutide, etc.), acetanilide type, urea type, sulfonylurea type (benzulfronmethyl, pro). Pyrisulfone, etc.), Benzofuranylalkylsulfonic acid (benfresate, etc.), Pyrimidyloxybenzoic acid (penoxyslam, etc.), Triazine (simetrin, etc.), Diazine, Diazole (pyrazolate, benzophenap, etc.), Bipyridylium, Dinitroaniline-based, aromatic carboxylic acid-based, imidazolinone-based, fatty acid-based, organic phosphorus-based, amino acid-based, tetrazolinone-based (fentrazamide, etc.), diphenyl ether-based (biphenox, etc.), oxazolidinedione-based (pentoxazone, etc.), nitrile-based, phenyl Phenylimide-based, cineole-based, indandione-based, benzofuran-based, triazolopyrimidine-based, oxadinone-based (oxadichromephon, etc.), allyltriazolinone-based, isourazole-based, pyrimidinylthiophthalide-based, triazolinone-based (ipphencarbazone, etc.), Examples include triketone-based (tefuryltrione, mesotrione, benzobicyclone, etc.) inorganic herbicides.

《Plant growth regulator》
Examples of the plant growth regulator include ethylene-based, auxin-based, cytokinin-based, and gibberellin-based.

The specific pesticide active ingredients contained in these are, for example, "Agricultural Chemicals Handbook 2016" (published by Japan Plant Protection Association), "SHIBUYA INDEX 13th Edition" (published by SHIBUYA INDEX Study Group), "The". It is described in "Pesticide Manual Sixteenth Edition" (published by British Crop Protection Council) and the like.

Further, as the pesticide active ingredient used in the present invention, if it fulfills the same purpose as the present invention and is applied as a water-floating pesticide preparation, the pesticide activity other than the above is conventionally known or will be developed in the future. Ingredients can also be applied.

The pesticide active ingredient may be used alone or in combination of two or more without any problem. The amount added is usually 0.01 to 60% by weight, preferably 0.05 to 50% by weight, in the formulation.

《Floating carrier》
Since the floating carrier used in the present invention has a hollow body, buoyancy is generated, so that it can float on the water surface and also has a function of a disintegration aid because it creates minute gaps in the formulation. It contributes to diffusivity in terms of floating property and disintegration property. Examples of the agent include those having a hollow body such as a shirasu balloon, a fly ash balloon, a ceramic balloon, and a synthetic resin hollow body. Further, since these components tend to have a brittle formulation hardness when the average particle size is too large, those having an average particle size of 200 μm or less are preferable.

In particular, considering the balance between floating property, disintegration property and formulation hardness, a shirasu balloon having an average particle size of 90 to 120 μm is preferable.

The amount of the floating carrier added that can be used in the present invention may be an amount sufficient to float the preparation on the water surface, and is usually 2.0 to 80% by weight, preferably 5.0 to 70% by weight. Moreover, you may use 1 type or 2 or more types from the above-mentioned.

<< Alkylnaphthalene Sulfone Na and Dialkyl Succinate Sulfonate Na >> (Anionic Surfactant)
Since the alkylnaphthalene sulfone Na and the dialkyl succinate sulfonate Na used in the present invention are anionic surfactants having a good balance between wettability and dispersibility, one of these anionic surfactants is used. By containing the above, it contributes to the disintegration and dispersibility of the preparation, and this function maintains the performance even after long-term storage. In addition, due to its wetting ability at the time of production, the amount of water added to the granulation can be reduced, and the load at the time of granulation can be reduced.

The amount of alkylnaphthalene sulfone Na and dialkyl succinate sulfonate Na that can be used in the present invention is 0.5 to 30% by weight, preferably 1 to 20% by weight, in the preparation.

<< Alkylnaphthalene sulfonic acid formaldehyde condensate Na, Naphthalene sulfonic acid formaldehyde condensate Na, partially desulfonated lignin sulfonate Na, and lignin sulfonate Na >> (additional anionic surfactant)
Diffusibility by adding one or more selected from alkylnaphthalene sulfonic acid formaldehyde condensate Na, naphthalene sulfonic acid formaldehyde condensate Na, and partially desulfonated lignin sulfonate Na to the water-floating pesticide preparation of the present invention. And enhance storage stability function.

Each component is a high molecular weight sulfonic acid-based surfactant having a molecular weight of several thousand to several tens of thousands, and its dispersibility is enhanced by the combined use with Na alkylnalnaphthalene sulfonate and Na dialkyl succinate sulfonate, and its effect is long-term. It is maintained even after storage.

When it contains a polyoxyalkylene alkyl ether phosphoric acid ester salt and a water-soluble alkylene glycol, which will be described later, it is selected from alkylnaphthalene sulfonic acid formaldehyde condensate Na, naphthalene sulfonic acid formaldehyde condensate Na, and lignin sulfonate Na. Diffusivity and storage stability functions are enhanced by adding one or more.

The amount of alkylnaphthalene sulfonic acid formaldehyde condensate Na, naphthalene sulfonic acid formaldehyde condensate Na, partially desulfonated lignin sulfonate Na, and lignin sulfonate Na that can be used in the present invention is 0.5 to 30 weight by weight in the preparation. %, preferably 1 to 20% by weight.

[式中、Ｒは、炭素数８〜１０の直鎖状または分岐鎖状のアルキル基を示し、Ａは炭素数２〜４のアルキレン基を示し、ｎは１〜２０の整数を示し、ｐおよびｑは、ｐ＋ｑ＝３かつｐ＝１または２である整数を示し、Ｍは水素原子、アルカリ金属原子、アンモニウム基、または有機アンモニウム基を示す。なお、Ｒ、Ａ、Ｍがそれぞれ複数ある場合は、それらの種類は同じでも異なってもよい。]
で表されるポリオキシアルキレンアルキルエーテルリン酸エステル塩は、すぐれた拡展力、湿潤性、分散性および水と接触することでゲル化する能力を有する。製剤が水に接触することで該成分が農薬活性成分あるいは浮遊性担体を取り込んだ形でゲル化することで、浮遊性担体により浮力を強化された状態で農薬活性成分をより遠くまで拡散させることが可能となる。また、ゲルが水に溶解する際、農薬活性成分の周囲には該成分が高濃度で存在するため、農薬活性成分に該成分が効率的に吸着し、ゲル状態解除後もさらに遠くまで農薬活性成分が拡散する。また、ゲル化能力は劣化することがないため、製剤への拡展力、分散力の付与効果および浮遊補助は長期保管後も継続される。<< Polyoxyalkylene alkyl ether phosphate ester salt >> (anionic surfactant)
The following general formula (I) used in the present invention

[In the formula, R represents a linear or branched alkyl group having 8 to 10 carbon atoms, A represents an alkylene group having 2 to 4 carbon atoms, n represents an integer of 1 to 20, and p. And q represent integers p + q = 3 and p = 1 or 2, and M represents a hydrogen atom, an alkali metal atom, an ammonium group, or an organic ammonium group. When there are a plurality of R, A, and M, the types may be the same or different. ]
The polyoxyalkylene alkyl ether phosphate salt represented by is excellent in spreading power, wettability, dispersibility and ability to gel on contact with water. When the pharmaceutical product comes into contact with water, the component gels in the form of incorporating the pesticide active ingredient or the floating carrier, so that the pesticide active ingredient is diffused farther in a state where the buoyancy is strengthened by the floating carrier. Is possible. Further, when the gel is dissolved in water, the component is present in a high concentration around the pesticide active component, so that the component is efficiently adsorbed on the pesticide active component, and the pesticide activity is further distant even after the gel state is released. Ingredients diffuse. In addition, since the gelling ability does not deteriorate, the spreading power to the pharmaceutical product, the effect of imparting the dispersing power, and the floating assistance are continued even after long-term storage.

In the present invention, examples of the alkylene group represented by A in the phosphoric acid ester salt represented by the general formula (I) include an ethylene group having 2 carbon atoms, a propylene group having 3 carbon atoms, and a butylene group having 4 carbon atoms. Be done.
In order to exert the spreading power and gelling ability in the present invention, the alkylene group preferably contains an ethylene group having 2 carbon atoms. The alkylene group represented by A may be only an ethylene group having 2 carbon atoms, or may have an ethylene group having 2 carbon atoms, a propylene group having 3 carbon atoms, a butylene group having 4 carbon atoms, or both. It may be included.
In the present invention, the alkyl group represented by R in the phosphoric acid ester salt represented by the general formula (I) has 8 to 10 carbon atoms in order to balance the solubility in water and the spreading force on the water surface. The alkyl group needs to have a linear or branched structure of, and examples of the alkyl group include an n-octyl group, an n-decyl group, an isodecyl group, and a 2-ethylhexyl group.
In the present invention, the phosphate ester salt represented by the general formula (I) is not particularly limited as long as the cation (M in the formula) paired with the phosphate ion does not lose the function of the present invention. Examples of the atom represented by M, include an alkali metal atom such as a hydrogen atom, a lithium atom, a sodium atom, or a potassium atom, and examples of the substituent include an organic ammonium such as an ammonium group, a methylammonium group, or a dimethylammonium group. The group is mentioned.
Since the manufacturing process includes a heat-drying step, the cation (M in the formula) is preferably ^{K +} , Na ⁺ , or H ^{+, which is difficult to volatilize even in the heat-drying step.}
In the present invention, the phosphoric acid ester salt represented by the general formula (I) has a number of phosphoric acid ester bonds of 1 (monoester) in order to balance the solubility in water and the spreading force on the water surface. ) Or 2 (diester). When the phosphoric acid ester salt is a monoester, p = 1 and q = 2. In this case, the alkyl group represented by R may be the same or different, and when it is a diester, p = 2. , Q = 1, and in this case, the atoms and the like represented by M may be the same or different.
In the present invention, the phosphoric acid monoester salt and the phosphoric acid diester salt represented by the general formula (I) may be used alone or in combination.

The amount of the polyoxyalkylene alkyl ether phosphoric acid ester salt that can be used in the present invention is 1 to 40% by weight, preferably 3 to 25% by weight, even if one or more of them are used in combination. There is no problem.

《Water-soluble alkylene glycol》
The water-soluble alkylene glycol used in the present invention is essential for exerting the function of the polyoxyalkylene alkyl ether phosphate salt. The characteristic of water-soluble alkylene glycol that has both hydrophilicity and lipophilicity is that when used in combination with polyoxyalkylene alkyl ether, it adjusts the water dissolution time of the gel that occurs when it comes into contact with water. As a result, not only the spreading power and the dispersing power of the polyoxyalkylene alkyl ether phosphate salt are maximized, but also the gel retains the floating carrier, thereby imparting a floating assisting effect to the pharmaceutical product. The following effects can also be obtained.

The water-soluble alkylene glycol that can be used in the present invention may be miscible with water, and examples thereof include ethylene glycol, propylene glycol, butylene glycol, pentylene glycol, and hexylene glycol, and one or two of these. There is no problem even if the above is used together.

The amount of the water-soluble alkylene glycol that can be used in the present invention is 0.5 to 20% by weight, preferably 1 to 10% by weight in the formulation.

《Binder》
Auxiliary binders include dextrin (roasted dextrin and enzyme-modified dextrin, etc.), acid-decomposed starch, oxidized starch, pregelatinized starch, etherified starch (carboxymethyl starch, hydroxyalkyl starch, etc.), esterified starch (acetate). Processed starches such as starches and phosphate starches), crosslinked starches and grafted starches, such as natural substances such as sodium alginate, Arabic gum, gelatin, tragant gum, locust bean gum, and casein, such as sodium carboxymethyl cellulose salt, hydroxyethyl cellulose, etc. Examples include, but are not limited to, cellulose derivatives such as hydroxypropyl cellulose, hydroxypropyl methyl cellulose, methyl cellulose, ethyl cellulose, and acetyl cellulose, as well as, but are not limited to, one or two of these, such as polyvinyl alcohol and polyvinylpyrrolidone. There is no problem even if the above is used together.

In addition, carboxymethyl cellulose Na is preferable from the viewpoint of dispersity.
When the polyoxyalkylene alkyl ether phosphoric acid ester salt and the water-soluble alkylene glycol are contained, carboxymethyl cellulose Na or polyvinyl alcohol is preferable from the viewpoint of disintegration dispersibility.
The content of the binder that can be used in the present invention is preferably 0.1 to 10% by weight.

<< Other auxiliary agents >>
In the water-floating pesticide preparation of the present invention, the following components may be added as an auxiliary agent in addition to the above-mentioned components as long as the effects of the present invention are not lost.

For example, examples of the surfactant include a nonionic surfactant, an anionic surfactant other than the above, a cationic surfactant, and an amphoteric surfactant.

Examples of the nonionic surfactant include polyoxyethylene alkylaryl ether, polyoxyethylene alkyl ether, polyoxyethylene arylaryl ether, polyoxyethylene alkyl ester, alkyl ester of sorbitan and the like.

Examples of anionic surfactants other than the above include dodecylbenzene sulfonate, alkyl sulfonate, lauryl sulfate, α-olefin sulfonate, polyoxyethylene alkyl sulfosuccinate, polyoxyethylene alkyl ether sulfate, and the like. Polyoxyethylene alkylaryl ether sulfate, polyoxyethylenearylphenyl ether phosphate, polyoxyethylene styrylphenyl ether phosphate, and (co) polymers of carboxylic acids such as acrylic acid and maleic acid, and styrene sulfone to them. Examples thereof include sodium salts and potassium salts obtained by copolymerizing acids, vinyl groups and the like.
The (co) polymers of carboxylic acids such as acrylic acid and maleic acid and the sodium and potassium salts obtained by copolymerizing them with styrene sulfonic acid, vinyl group, etc. contribute to the disintegration and dispersibility of the preparation. Can be expected.

Examples of the cationic surfactant include an alkyltrimethylammonium salt, an alkyldimethylbenzylammonium salt, and an alkylpyridinium salt.

Examples of amphoteric surfactants include dialkylaminoethyl betaine and alkyldimethylbenzyl betaine.

The surfactant that can be used in the present invention is not limited to these examples, and one type or two or more types may be used in combination. The content of the surfactant in the formulation is preferably 0.1 to 20% by weight.

Examples of the solid carrier that can be used in the present invention include those exemplified below.

For example, clay, quartz, diatomaceous earth, sepiolite, dolomite, choke, kaolin, pyrophyllite, sericite, halosite, metahalosite, bentonite clay, diatomaceous earth, pottery stone, siegrite, allophen, silas, Calcined products of natural minerals such as glitter, talc, sepiolite, sepiolite, bentonite, hectrite, zeolite, and diatomaceous earth, such as calcined clay, pearlite, vermiculite, attapargas clay, and calcined diatomaceous earth, eg, carbonate. Inorganic salts such as magnesium, calcium carbonate, sodium carbonate, sodium hydrogen carbonate, ammonium sulfate, sodium sulfate, magnesium sulfate, diammonium hydrogen phosphate, ammonium dihydrogen phosphate, and potassium chloride, such as glucose, fructose, sucrose, and lactose. Sugars such as starch, powdered cellulose, and polysaccharides such as dextrin, such as urea, urea derivatives, benzoic acid, and organic substances such as salts of benzoic acid, as well as wood flour, corn stalks, walnut shells, tobacco stalks, etc. Plants, white carbon and the like.

The amount of the solid carrier that can be used in the present invention is 3 to 95% by weight, preferably 5 to 90% by weight, in the formulation.

Antiseptic and antibacterial agents include potassium sorbate, p-chloro-m-xylenol, butyl p-oxybenzoate, 1,2-benzoisothiazolin-3-one, 5-chloro-2-methyl-4-isothiazolin-3. -On, 2-methyl-4-isothiazolin-3-one, etc., as pH adjusters such as hydrochloric acid, sulfuric acid, citric acid, phosphoric acid, and magnesium carbonate, and as stabilizers for pesticide active ingredients, oxidation An inhibitor, an ultraviolet inhibitor, a crystal precipitation inhibitor, and the like may be added, but the present invention is not limited to the auxiliary agents exemplified here.

The amount of these auxiliary agents that can be used in the present invention is 0.01 to 15% by weight, preferably 0.1 to 10% by weight, in the formulation.

<B. Physical characteristics of the drug>
In the water-floating pesticide preparation of the present invention, in order to show good floating and diffusivity and to show an effect of excellent storage stability, not only the preparation component but also the following << Major axis of bottom surface of grain / Physical properties of pesticide preparations such as "minor diameter ratio", "particle size", and "number of grains per gram" are required.

<< Major axis / minor axis ratio of the bottom surface of the grain >>
In the water-floating pesticide formulation of the present invention, the bottom surface of the granules refers to the surface derived from the screen hole at the time of granulation, and the major axis and the minor axis on the bottom surface are straight lines (diameters) passing through the center of the bottom surface. The maximum diameter is the major axis and the minimum diameter is the minor axis.

Therefore, the major axis / minor axis ratio of the bottom surface of the grain is determined by cutting the bottom surface of the preparation with a cutter so that the bottom surface is a cross section, and then measuring the maximum diameter (major axis) and the minimum diameter (minor axis) of the cross section with a microscope. However, it refers to a value obtained by calculating the ratio of the major axis to the minor axis as the average value of 10 preparations.

In the water-floating pesticide preparation of the present invention, adjusting the major axis / minor axis ratio at the bottom surface of the granules affects the floating property, diffusibility, and storage stability (diffusion distance, diffusion distance of the drug after long-term storage) of the drug. Contribute. It is essential to adjust the major axis / minor axis ratio in the range of 1.1 to 1.4 in order to impart the effect of improving the floating property and diffusivity. The major axis / minor axis ratio is a parameter that expresses the shape of the pharmaceutical product. At 1.0 (minimum value), the shape of the bottom surface is a perfect circle, and the larger the value, the flatter the grain. When the major axis / minor axis ratio is 1.0, the movement of the pharmaceutical product on the water surface is slow and causes a decrease in diffusivity, and when it exceeds 1.4, the movement on the water surface is fast, but it quickly disintegrates and disperses. As a result, the diffusion distance of the active ingredient is shortened.
When the polyoxyalkylene alkyl ether phosphate salt and propylene glycol are contained, the gel generated when the product comes into contact with water increases the disintegration time of the preparation into water. Therefore, the upper limit of the major axis / minor axis ratio is 1. Up to 6 is possible. Regarding the reach distance and diffusion distance of the pharmaceutical product after long-term storage, when the major axis / minor axis ratio is 1.1 or more, quality deterioration after long-term storage is suppressed. These factors are more susceptible to the buoyancy of water due to the increase in the area of the formulation that comes into contact with the water surface as the major axis / minor axis ratio increases, or the release rate of the surfactant on the water surface is high. It is presumed that this will improve the efficiency of collapse and dispersion of the water surface.

As a method for adjusting the major axis / minor axis ratio, the extrusion hole diameter at the time of granulation is adjusted in the extrusion granulation process, and then a machine such as a drum type granulator or a mulmerizer in the granulation process is rotated. A method of controlling the major axis / minor axis ratio by rotating the granulated product before drying and controlling the centrifugal force can be mentioned.
The granulated product before drying is soft because the binder contains water and is in a swollen state, and if the granulated particle size (extruded hole diameter) is large, it is also affected by its own weight. Therefore, when a rotational motion is applied, centrifugal force and its own weight act to flatten the cross section of the granulated product (generation of major axis and minor axis).

<< Particle size >>
In the water-floating pesticide formulation of the present invention, the particle size is based on the weight of the formulation remaining on the 1.70 mm mesh sieve when 100 g of the formulation is sieved with test sieves of 2.80 mm and 1.70 mm mesh. , Calculated from the following equation (1).

In the water-floating pesticide preparation of the present invention, adjusting the particle size contributes to the floating and diffusivity of the preparation. From the viewpoint of the balance between floating property and diffusivity, it is essential that the particle size is 80% by weight or more in the range of 2.80 mm to 1.70 mm, and more preferably 90% by weight or more. In terms of particle size, those smaller than the particle size range have less floating carrier and therefore tend to sink due to less buoyancy, and those with larger particle size have a larger weight per grain and slower movement on the water surface. , The diffusivity becomes worse.

As a method for adjusting the particle size, the size of the extruded pores at the time of granulation is adjusted in the extrusion granulation step, and then the grain length of the granulated product before drying is appropriately adjusted in the granulation step to control the particle size. The method can be mentioned. The sizing machine used for adjusting the particle size is not particularly limited, but is a drum sizing machine, a rotary sizing machine such as a malmerizer, or a crushing sizing machine such as a pin mill, an oscillator, a lander mill, or a nebulizer. Can be used. From the viewpoint of economic efficiency and labor saving during manufacturing, a rotary sizing machine such as a drum type sizing machine capable of simultaneously adjusting the major axis / minor axis ratio of the bottom surface of the grains is preferable.

<< Number of grains per 1g >>
In the water-floating pesticide formulation of the present invention, the number of grains per 1 g is a value obtained by measuring the number of grains of 5.0 g of the weighed formulation with a grain number measuring device and dividing the measured value by one-fifth (rounded to the nearest whole number). Indicated by.

In the water-floating pesticide preparation of the present invention, adjusting the number of grains per gram contributes to the floating and diffusible properties of the preparation. From the viewpoint of the balance between floating property and diffusivity, it is essential that the number of grains per gram is 50 to 150. For the same reason as the previous particle size, those with more than 150 grains per gram have smaller grains and are more likely to sink due to less buoyancy, and those with less than 50 grains have heavier weight per grain and are on the water surface. The movement becomes slower and the diffusivity becomes worse.
When the polyoxyalkylene alkyl ether phosphate salt and propylene glycol are contained, even grains having a small buoyancy diffuse farther due to the enhanced diffusivity, so that the upper limit of the number of grains per gram can be up to 200. ..

Examples of the method for adjusting the number of grains per 1 g include a method of controlling the number of grains per 1 g by crushing the granulated product before drying in the granulation step. The sizing machine used for adjusting the number of grains is not particularly limited, but is a drum type sizing machine, a rotary sizing machine such as a malmerizer, a pin mill, an oscillator, a Randell mill, a nebulizer, and a crushing type sizing machine. A machine can be used. From the viewpoint of economic efficiency and labor saving during manufacturing, a rotary sizing machine such as a drum type sizing machine capable of simultaneously adjusting the major axis / minor axis ratio and the particle size of the bottom surface of the grains is preferable.

<Manufacturing method of water-floating pesticide preparation>
The water-floating pesticide preparation of the present invention is produced by an extrusion granulation method, and is advantageous in terms of economy and production efficiency.

As a manufacturing process, one or more selected from agrochemical active ingredient, a floating carrier, Na alkylnaphthalene sulfonate and Na dialkyl succinate sulfonate, if necessary, a polyoxyalkylene alkyl ether phosphate ester salt, if necessary. Then, one or more selected from alkylnaphthalene sulfonate formaldehyde condensate Na, naphthalene sulfonate formaldehyde condensate Na, partially desulfonated lignin sulfonate Na, and lignin sulfonate Na, and various auxiliary agents are added. Mix evenly using a juice mixer, hammer mill, Ligno mixer or ribbon mixer. Water is added to this mixture and kneaded using a double-arm kneader or a ribbon mixer. When the pesticide active ingredient is wet-ground and added as a slurry for reasons such as mixing accuracy, it is added together with water at the time of kneading.

In the granulation step and the granulation step after the kneading step, the physical characteristics of the water-floating pesticide preparation of the present invention are adjusted. In the sizing process, the major axis / minor axis ratio, particle size, and number of grains on the bottom surface of the grains can be adjusted at once, or the major axis / minor axis ratio on the bottom surface of the grains can be adjusted and then the particle size and number of grains can be adjusted. good. It is preferable to omit the number of steps and adjust all at once from the viewpoint of improving economic efficiency at the time of manufacturing.

In the granulation and sizing steps, first, the above mixture is granulated using an extrusion granulator such as a basket-type granulator or a screw-type granulator. The extrusion hole diameter at the time of granulation is preferably 2.8 to 3.0 mm in order to adjust the physical properties of the water-floating pesticide preparation of the present invention. With the extruded pore diameter, the water-floating pesticide preparation of the present invention of the present invention is obtained by sizing the obtained granules with a machine such as a drum-type granulator or a mulmerizer that applies centrifugal force. In addition to setting the major axis / minor axis ratio on the bottom surface to 1.1 to 1.4, the particle size should be 80% by weight or more in the range of 2.80 mm to 1.70 mm, and the number of grains per gram should be 50 to 150. Can be sized. After sizing, it is dried using a fluidized bed dryer, a bed-type dryer, or the like, and then sieved to obtain the water-floating pesticide preparation used in the present invention.

When a pesticide active ingredient for which elution is to be promoted is used in combination, a coating step can be added as long as the effect of the present invention is not lost.

<Usage form of water-floating pesticide preparation>
The water-floating pesticide preparation of the present invention is directly sprayed without entering the paddy field. Examples of the spraying method include hand-spraying, spraying in a container such as a cup, mechanical spraying with a power sprayer, aerial spraying using a radio-controlled helicopter, a drone, etc., and water sprinkling for water flowing into a paddy field. Considering the aspect of avoiding the exposure of the sprayer to radiation, the spraying method that does not come into direct contact with the pharmaceutical product is preferable. The application rate is usually 50 to 500 g, preferably 75 to 300 g per 10a.

Hereinafter, the present invention will be specifically described based on Examples, but the present invention is not limited thereto.

In the following Examples and Comparative Examples, "part" means "part by weight" and "%" means "% by weight".

Further, in the following Examples and Comparative Examples, the devices (microscope, sieve shaker, grain number measuring device) used for measuring the major axis / minor axis ratio, particle size, and grain number of the water-floating pesticide preparation are respectively. VHX-5000 (manufactured by Keyence Co., Ltd.) Sieve shaker Low tap type (manufactured by Iida Seisakusho Co., Ltd.), Multi-auto counter KC-1M5 type (manufactured by Fujiwara Seisakusho Co., Ltd.).

[Example 1]
Kasugamycin 24.0 parts (bactericidal active ingredient), silas balloon (average particle size 70-90 μm) (floating carrier) 25.0 parts, alkylnaphthalene sulfonate Na 3.0 parts, dextrin 5.0 parts, bentonite 10.0 A powder mixture was obtained by pulverizing and mixing 30.0 parts of pearlite and 3.0 parts of clay with a hammer mill (sample mill KIIW-1, manufactured by Dalton). The obtained powder mixture was placed in a double-arm kneader (KDHJ, manufactured by Dalton) and kneaded for 15 minutes after water addition. Next, this hydrolyzed product was granulated by an extrusion granulator equipped with a basket-type screen having a pore size of 3.0 mm. The obtained granulated product was pre-dried, sized with a drum-type granulator, and dried with a fluidized bed dryer. This was sieved at 3.35 mm to 2.00 mm to obtain a water-floating pesticide preparation. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 98.

[Example 2]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), fly ash balloon (average particle size 80 to 120 μm) (floating carrier) 30.0 parts, 1.5 parts of dialkylsuccinate sulfonic acid Na, 2.0 parts of carboxymethyl cellulose. A water-floating pesticide preparation was prepared according to Example 1 with 35.0 parts of pearlite, 7.5 parts of clay, and a particle size of 2.8 mm. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 105.

[Example 3]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), 2.0 parts of acrylonitrile resin balloon (average particle size 20-40 μm) (floating carrier), 3.0 parts of Na alkylnaphthalene sulfonate, 2.0 parts of Na polyacrylate. The water-floating pesticide preparation was prepared according to Example 1 with 2.0 parts of Nacarboxymethylcellulose, 57.0 parts of pearlite, 10.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 113.

[Example 4]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), ceramic balloon (average particle size 20 to 150 μm) (suspended carrier) 25.0 parts, Na alkylnaphthalene sulfonate 3.0 parts, Na carboxymethyl cellulose 2.0 parts, The water-floating pesticide preparation was prepared according to Example 1 with 36.0 parts of diatomaceous earth, 10.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 93% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.1, and the number of grains per 1 g was 83.

[Example 5]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), silas balloon (average particle size 70 to 90 μm) (suspended carrier) 30.0 parts, dialkylsuccinate sulfonic acid Na 1.5 parts, and acrylic acid-maleic acid. The polymer Na 2.0 parts, carboxymethyl cellulose Na 3.0 parts, bentonite 10.0 parts, pearlite 20.0 parts, white carbon 4.5 parts, clay 5.0 parts, particle size 2.8 mm, Example 1 A water-floating pesticide preparation was prepared according to the above. The particle size of the obtained pharmaceutical product was 95% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 88.

[Example 6]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 30.0 parts, Na 3.0 part of alkylnaphthalene sulfonate, acrylic-methacrylic acid copolymer. Na 2.0 part, carboxymethyl cellulose Na 3.0 part, diatomaceous earth 33.0 part, clay 5.0 part, particle size 2.8 mm were prepared, and a water floating pesticide preparation was prepared according to Example 1. The particle size of the obtained pharmaceutical product was 88% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 96.

[Example 7]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, dialkyl succinate sulfonate Na 1.5 parts, polyacrylic acid Na 3.0. Part, carboxymethyl cellulose Na 3.0 part, diatomaceous earth 37.0 part, clay 6.5 part, particle size 3.0 mm, and water floating pesticide preparation was prepared according to Example 1. The particle size of the obtained pharmaceutical product was 87% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 110.

[Example 8]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 30.0 parts, Na of alkylnaphthalene sulfonate 3.0 parts, acrylic-maleic acid copolymer. Na 3.0 part, carboxymethyl cellulose Na 3.0 part, pearlite 32.0 part, clay 5.0 part, particle size 3.0 mm, and water floating pesticide preparation was prepared according to Example 1. The particle size of the obtained pharmaceutical product was 96% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 98.

[Example 9]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 30.0 parts, dialkyl succinate sulfonic acid Na 1.5 parts, acrylic acid-vinyl sulfonic acid. A water-floating pesticide preparation was prepared according to Example 1 with 2.0 parts of copolymer Na, 2.0 parts of carboxymethyl cellulose Na, 34.5 parts of pearlite, 6.0 parts of clay, and a particle size of 2.8 mm. .. The particle size of the obtained pharmaceutical product was 97% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 87.

[Example 10]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), silas balloon (average particle size 70 to 90 μm) (floating carrier) 30.0 parts, Na 3.0 parts of alkylnaphthalene sulfonic acid, and formaldehyde condensate of alkylnaphthalene sulfonic acid. Na 3.0 parts, acrylic-methacrylic acid copolymer Na 2.0 parts, carboxymethyl cellulose Na 2.0 parts, pearlite 28.5 parts, clay 7.5 parts, particle size 2.8 mm, conforming to Example 1. Prepared a water-floating pesticide preparation. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 76.

[Example 11]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), fly ash balloon (average particle size 80 to 120 μm) (floating carrier) 30.0 parts, 1.5 parts of Na dialkylsuccinate sulfonate, partially desulfonated lignin. Na sulfonate 3.0 parts, Na polyacrylate parts 2.0 parts, Carboxymethyl cellulose Na 2.0 parts, Bentnite 10.0 parts, Parlite 18.5 parts, White carbon 5.0 parts, Clay 4.0 parts, particle size formation The thickness was set to 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 1. The particle size of the obtained pharmaceutical product was 87% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 93.

[Example 12]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), ceramic balloon (average particle size 20 to 150 μm) (floating carrier) 30.0 parts, Na of alkylnaphthalene sulfonate 3.0 parts, formaldehyde condensate of naphthalene sulfonate Na3. .0 parts, acrylic-vinyl sulfonic acid copolymer Na 2.0 parts, carboxymethyl cellulose Na 2.0 parts, bentonite 10.0 parts, diatomaceous soil 21.0 parts, clay 5.0 parts, particle size 2.8 mm. A water-floating pesticide preparation was prepared according to Example 1. The particle size of the obtained pharmaceutical product was 95% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.1, and the number of grains per 1 g was 85.

[Example 13]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), 2.0 parts of acrylonitrile resin balloon (average particle size 20-40 μm) (suspended carrier), 1.5 parts of Na dialkylsuccinate sulfonate, and partially desulfonated lignin. Example 1 with 3.0 parts of Na sulfonate, 2.0 parts of Na acrylate-maleic acid copolymer, 2.0 parts of Na carboxymethyl cellulose, 55.5 parts of diatomaceous soil, 10.0 parts of clay, and 3.0 mm of particle size. A water-floating pesticide preparation was prepared according to the above. The particle size of the obtained pharmaceutical product was 95% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 68.

[Example 14]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 30.0 parts, Na 3.0 parts of alkylnaphthalene sulfonic acid, and formaldehyde condensate of alkylnaphthalene sulfonic acid. Na 3.0 parts, acrylic-vinyl sulfonic acid copolymer Na 3.0 parts, carboxymethyl cellulose Na 2.0 parts, bentonite 10.0 parts, pearlite 22.0 parts, clay 3.0 parts, particle size 2.8 mm. , A water-floating pesticide preparation was prepared according to Example 1. The particle size of the obtained pharmaceutical product was 88% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 111.

[Example 15]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 30.0 parts, 1.5 parts of dialkylsuccinate sulfonate Na, naphthalene sulfonic acid formaldehyde condensate. Na 3.0 parts, acrylate-methacrylic acid copolymer Na 3.0 parts, carboxymethyl cellulose Na 3.0 parts, bentonite 10.0 parts, pearlite 10.0 parts, white carbon 7.5 parts, clay 8.0 parts, A water-floating pesticide preparation was prepared according to Example 1 with a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 105.

[Example 16]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 30.0 parts, Na of alkylnaphthalene sulfonate 3.0 parts, partially desulfonated lignin sulfonic acid. Na 3.0 parts, acrylic-maleic acid copolymer Na 3.0 parts, carboxymethyl cellulose Na 3.0 parts, pearlite 29.0 parts, clay 5.0 parts, particle size 3.0 mm, conforming to Example 1. Prepared a water-floating pesticide preparation. The particle size of the obtained pharmaceutical product was 94% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 121.

[Example 17]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 30.0 parts, 1.5 parts of dialkylsuccinate sulfonic acid Na, alkylnaphthalene sulfonic acid formaldehyde condensation. Na 3.0 parts, Na 3.0 parts polyacrylate, 3.0 parts Na carboxymethyl cellulose, 30.5 parts diatomaceous soil, 5.0 parts clay, particle size 2.8 mm, floating on the water surface according to Example 1. A sex pesticide preparation was prepared. The particle size of the obtained pharmaceutical product was 93% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 83.

[Example 18]
Pymetrodin 12.0 parts (insecticidal active ingredient), silas balloon (average particle size 70-90 μm) (suspended carrier) 25.0 parts, alkylnaphthalene sulfonic acid Na 3.0 parts, polyvinyl alcohol 3.0 parts, pearlite 47. 0 parts and 10.0 parts of clay were pulverized and mixed with a hammer mill (sample mill KIIW-1, manufactured by Dalton) to obtain a powder mixture. The obtained powder mixture was placed in a double-arm kneader (KDHJ, manufactured by Dalton) and kneaded for 15 minutes after water addition. Next, this hydrolyzed product was granulated by an extrusion granulator equipped with a basket-type screen having a pore size of 3.0 mm. The obtained granulated product was pre-dried, sized with a drum-type granulator, and dried with a fluidized bed dryer. This was sieved at 3.35 mm to 2.00 mm to obtain a water-floating pesticide preparation. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 89.

[Example 19]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), fly ash balloon (average particle size 80 to 120 μm) (floating carrier) 25.0 parts, 1.5 parts of dialkylsuccinate sulfonic acid Na, 3.0 parts of carboxymethyl cellulose. A water-floating pesticide preparation was prepared according to Example 16 with 48.5 parts of pearlite, 10.0 parts of clay, and a particle size of 2.8 mm. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 97.

[Example 20]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), 2.0 parts of acrylonitrile resin balloon (average particle size 20-40 μm) (floating carrier), 3.0 parts of Na alkylnaphthalene sulfonate, 3.0 parts of Na polyacrylate. A water-floating pesticide preparation was prepared according to Example 18 with 2.0 parts of Nacarboxymethylcellulose, 60.0 parts of pearlite, 18.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 88% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 106.

[Example 21]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), 30.0 parts of ceramic balloon (average particle size 20 to 150 μm) (suspended carrier), 3.0 parts of Naalkylnaphthalene sulfonate, 2.0 parts of carboxymethyl cellulose. The water-floating pesticide preparation was prepared according to Example 18 with 43.0 parts of diatomaceous earth, 10.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 93% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 82.

[Example 22]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), silas balloon (average particle size 70 to 90 μm) (floating carrier) 30.0 parts, 1.5 parts of dialkylsuccinate sulfonic acid Na, and acrylic acid-maleic acid. Example 18: 2.0 parts of polymer Na, 2.0 parts of carboxymethyl cellulose Na, 10.0 parts of bentonite, 30.0 parts of pearlite, 5.0 parts of white carbon, 7.5 parts of clay, and 2.8 mm of particle size. A water-floating pesticide preparation was prepared according to the above. The particle size of the obtained pharmaceutical product was 96% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 88.

[Example 23]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), 30.0 parts of silas balloon (average particle size 90 to 120 μm) (suspended carrier), 3.0 parts of Na alkylnaphthalene sulfonate, acrylic-methacrylic acid copolymer. Na 2.0 part, carboxymethyl cellulose Na 3.0 part, diatomaceous earth 40.0 part, clay 10.0 part, particle size 2.8 mm were prepared, and a water floating pesticide preparation was prepared according to Example 18. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 93.

[Example 24]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), 30.0 parts of silas balloon (average particle size 90 to 120 μm) (suspended carrier), 1.5 parts of Na dialkylsuccinate sulfonate, 2.0 parts of Na polyacrylate. A water-floating pesticide preparation was prepared according to Example 18 with 3.0 parts of Nacarboxymethylcellulose, 45.0 parts of diatomaceous earth, 6.5 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 97.

[Example 25]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 25.0 parts, Na 3.0 part of alkylnaphthalene sulfonate, acrylic-maleic acid copolymer. Na 3.0 part, carboxymethyl cellulose Na 2.0 part, pearlite 45.0 part, clay 10.0 part, particle size 3.0 mm, and water floating pesticide preparation was prepared according to Example 18. The particle size of the obtained pharmaceutical product was 94% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 95.

[Example 26]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 25.0 parts, 1.5 parts of dialkylsuccinate sulfonic acid Na, acrylic acid-vinyl sulfonic acid. A water-floating pesticide preparation was prepared according to Example 18 with 3.0 parts of copolymer Na, 3.0 parts of carboxymethyl cellulose Na, 48.5 parts of pearlite, 7.0 parts of clay, and a particle size of 2.8 mm. .. The particle size of the obtained pharmaceutical product was 97% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 107.

[Example 27]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), silas balloon (average particle size 70 to 90 μm) (suspended carrier) 28.0 parts, Na of alkylnaphthalene sulfonate 3.0 parts, formaldehyde condensate of alkylnaphthalene sulfonic acid. Na 3.0 parts, acrylic-methacrylic acid copolymer Na 3.0 parts, carboxymethyl cellulose Na 3.0 parts, pearlite 38.0 parts, clay 10.0 parts, particle size 2.8 mm, conforming to Example 18. Prepared a water-floating pesticide preparation. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 91.

[Example 28]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), fly ash balloon (average particle size 80 to 120 μm) (floating carrier) 28.0 parts, 1.5 parts of dialkylsuccinate sulfonate Na, partially desulfonated lignin. Na sulfonate 3.0 parts, Na polyacrylate parts 3.0 parts, Carboxymethyl cellulose Na 2.0 parts, Bentnite 10.0 parts, Parlite 30.0 parts, White carbon 5.0 parts, Clay 5.5 parts, particle size formation The water-floating pesticide preparation was prepared according to Example 18 with a thickness of 3.0 mm. The particle size of the obtained pharmaceutical product was 87% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 83.

[Example 29]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), ceramic balloon (average particle size 20 to 150 μm) (floating carrier) 25.0 parts, Na of alkylnaphthalene sulfonate 3.0 parts, formaldehyde condensate of naphthalene sulfonate Na3. .0 parts, acrylic-vinyl sulfonic acid copolymer Na 3.0 parts, carboxymethyl cellulose Na 3.0 parts, bentonite 10.0 parts, diatomaceous soil 36.0 parts, clay 5.0 parts, particle size 2.8 mm. A water-floating pesticide preparation was prepared according to Example 18. The particle size of the obtained pharmaceutical product was 98% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 86.

[Example 30]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), 2.0 parts of acrylonitrile resin balloon (average particle size 20-40 μm) (suspended carrier), 1.5 parts of Na dialkylsuccinate sulfonate, and partially desulfonated lignin. Na sulfonate 3.0 parts, acrylic acid-maleic acid copolymer Na 2.0 parts, carboxymethyl cellulose Na 2.0 parts, pearlite 35.0 parts, diatomaceous earth 35.0 parts, clay 7.5 parts, particle size 3. The thickness was set to 0 mm, and a water-floating pesticide preparation was prepared according to Example 18. The particle size of the obtained pharmaceutical product was 93% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 95.

[Example 31]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 28.0 parts, Na of alkylnaphthalene sulfonate 3.0 parts, formaldehyde condensate of alkylnaphthalene sulfonic acid. Na 3.0 parts, acrylic-vinyl sulfonic acid copolymer Na 3.0 parts, carboxymethyl cellulose Na 2.0 parts, bentonite 10.0 parts, pearlite 30.0 parts, clay 9.0 parts, particle size 2.8 mm. , A water-floating pesticide preparation was prepared according to Example 18. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 108.

[Example 32]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 30.0 parts, 1.5 parts of dialkylsuccinate sulfonate Na, naphthalene sulfonic acid formaldehyde condensate. Na 3.0 parts, acrylate-methacrylic acid copolymer Na 3.0 parts, carboxymethyl cellulose Na 2.0 parts, bentonite 10.0 parts, pearlite 19.5 parts, white carbon 15.0 parts, clay 4.0 parts, A water-floating pesticide preparation was prepared according to Example 18 with a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 90.

[Example 33]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 30.0 parts, Na 3.0 part of alkylnaphthalene sulfonate, partially desulfonated lignin sulfonic acid. Na 3.0 parts, acrylic-maleic acid copolymer Na 2.0 parts, carboxymethyl cellulose Na 2.0 parts, pearlite 40.0 parts, clay 8.0 parts, particle size 3.0 mm, conforming to Example 18. Prepared a water-floating pesticide preparation. The particle size of the obtained pharmaceutical product was 95% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 88.

[Example 34]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 30.0 parts, 1.5 parts of dialkylsuccinate sulfonic acid Na, alkylnaphthalene sulfonic acid formaldehyde condensation. Na 3.0 parts, Na 2.0 parts polyacrylate, 2.0 parts Na carboxymethyl cellulose, 44.5 parts diatomaceous soil, 5.0 parts clay, particle size 2.8 mm, floating on the water surface according to Example 18. A sex pesticide preparation was prepared. The particle size of the obtained pharmaceutical product was 96% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 99.

[Example 35]
After mixing 10.0 parts of ipfencarbazone (herbicidal active ingredient), 1.0 part of Naalkylnaphthalene sulfonate, and 14.0 parts of water, the average particle size becomes 1.0 μm with Dynomil (manufactured by Symmulenterprises). Wet pulverization to obtain a slurry. In addition, silas balloon (average particle size 70 to 90 μm) (floating carrier) 25.0 parts, alkylnaphthalene sulfonic acid Na 2.0 parts, polyvinyl alcohol 2.0 parts, bentonite 5.0 parts, pearlite 42.0 parts, 13.0 parts of clay was pulverized and mixed with a hammer mill (sample mill KIIW-1, manufactured by Dalton) to obtain a powder mixture. The obtained slurry and powder mixture were placed in a double-arm kneader (KDHJ, manufactured by Dalton) and kneaded for 15 minutes after water addition. Next, this hydrolyzed product was granulated by an extrusion granulator equipped with a basket-type screen having a pore size of 3.0 mm. The obtained granulated product was pre-dried, sized with a drum-type granulator, and dried with a fluidized bed dryer. This was sieved at 3.35 mm to 2.00 mm to obtain a water-floating pesticide preparation. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 109.

[Example 36]
The pharmaceutical composition consists of 10.0 parts of ipphencarbazone (herbicidal active ingredient), fly ash balloon (average particle size 80 to 120 μm) (suspended carrier) 28.0 parts, 1.5 parts of Na dialkylsuccinate sulfonate, carboxymethyl cellulose. 2.0 parts of Na, 51.5 parts of pearlite, 7.0 parts of clay (of which the composition used for the slurry is 10.0 parts of ipphencarbazone, 1.0 part of Na dialkylsuccinate sulfonate, 14.0 parts of water). A water-floating pesticide preparation was prepared according to Example 35 with a particle size of 2.8 mm. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 115.

[Example 37]
The pharmaceutical composition consists of 10.0 parts of ipphencarbazone (herbicidal active ingredient), 2.0 parts of acrylonitrile resin balloon (average particle size 20-40 μm) (floating carrier), 3.0 parts of Naalkylnaphthalene sulfonic acid, polyacrylic acid. Na 2.0 parts, carboxymethyl cellulose Na 3.0 parts, pearlite 70.0 parts, clay 10.0 parts (of which the composition used for the slurry is ipphencarbazone 10.0 parts, alkylnaphthalene sulfonic acid Na 1.0 parts, Water 14.0 parts), the particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 35. The particle size of the obtained pharmaceutical product was 88% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 123.

[Example 38]
The pharmaceutical composition consists of 10.0 parts of ipphencarbazone (herbicidal active ingredient), ceramic balloon (average particle size 20 to 150 μm) (floating carrier) 28.0 parts, Na of alkylnaphthalene sulfonate 3.0 parts, Na2 polyacrylate. 0.0 part, carboxymethyl cellulose Na 3.0 part, diatomaceous soil 48.0 part, clay 8.0 part (of which the composition used for the slurry is ipphencarbazone 10.0 part, alkylnaphthalene sulfonic acid Na 1.0 part, water. 14.0 parts), the particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 35. The particle size of the obtained pharmaceutical product was 92% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 103.

[Example 39]
The pharmaceutical composition consists of 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 70 to 90 μm) (floating carrier) 25.0 parts, 1.5 parts of dialkylsuccinate sulfonic acid Na, acrylic acid- Maleic acid copolymer Na 2.0 parts, carboxymethyl cellulose Na 3.0 parts, bentonite 10.0 parts, pearlite 33.5 parts, white carbon 10.0 parts, clay 5.0 parts (of which the composition used for the slurry is The ipphencarbazone was 10.0 parts, dialkyl succinate sulfonate Na was 1.0 part, and water was 14.0 parts), and the particle size was 2.8 mm. The particle size of the obtained pharmaceutical product was 95% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 100.

[Example 40]
The pharmaceutical composition consists of 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 90-120 μm) (floating carrier) 30.0 parts, Na 3.0 part of alkylnaphthalene sulfonate, acrylic-methacrylic acid. 2.0 parts of copolymer Na, 2.0 parts of carboxymethyl cellulose Na, 43.0 parts of diatomaceous soil, 10.0 parts of clay (of which the composition used for the slurry is 10.0 parts of ipphencarbazone, Na 1. of alkylnaphthalene sulfonate. 0 part, 14.0 parts of water), the particle size was 2.8 mm, and a water-floating pesticide preparation was prepared according to Example 35. The particle size of the obtained pharmaceutical product was 87% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.1, and the number of grains per 1 g was 123.

[Example 41]
The pharmaceutical composition consists of 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 25.0 parts, 1.5 parts of dialkylsuccinate sulfonic acid Na, polyacrylic acid. Na 3.0 parts, carboxymethyl cellulose Na 3.0 parts, diatomaceous soil 50.0 parts, clay 7.5 parts (of which the composition used for the slurry is ipphencarbazone 10.0 parts, dialkylsuccinate sulfonic acid Na 1.0 parts. , Water 14.0 parts), and the particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 35. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 109.

[Example 42]
The pharmaceutical composition consists of 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 90-120 μm) (floating carrier) 30.0 parts, Na 3.0 part of alkylnaphthalene sulfonic acid, acrylic-maleic acid. Copolymer Na 3.0 parts, carboxymethyl cellulose Na 2.0 parts, pearlite 45.0 parts, clay 7.0 parts (of which the composition used for the slurry is ipphencarbazone 10.0 parts, alkylnaphthalene sulfonate Na1. 0 part, 14.0 parts of water), the particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 35. The particle size of the obtained pharmaceutical product was 96% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 103.

[Example 43]
The pharmaceutical composition is 10.0 parts of ipphencarbazone (herbicidal active ingredient), 28.0 parts of silas balloon (average particle size 90-120 μm) (floating carrier), 1.5 parts of Na dialkylsuccinate sulfonic acid, acrylic acid- Vinyl sulfonic acid copolymer Na 3.0 parts, carboxymethyl cellulose Na 3.0 parts, pearlite 50.0 parts, clay 4.5 parts (of which the composition used for the slurry is ipphencarbazone 10.0 parts, dialkylsuccinate Na sulfonate (1.0 part), water (14.0 part), and particle size of 2.8 mm were used to prepare a water-floating pesticide preparation according to Example 35. The particle size of the obtained pharmaceutical product was 95% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 126.

[Example 44]
The composition of the preparation was 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 70 to 90 μm) (suspended carrier) 28.0 parts, Na of alkylnaphthalene sulfonic acid 3.0 parts, alkylnaphthalene sulfonic acid. Formaldehyde condensate Na 3.0 parts, acrylic-methacrylic acid copolymer Na 3.0 parts, carboxymethyl cellulose Na 2.0 parts, pearlite 46.0 parts, clay 5.0 parts (of which the composition used for the slurry is ipphencarba) A pesticide preparation floating on the surface of the water was prepared according to Example 35 with 10.0 parts of zone, 1.0 part of Na alkylnaphthalene sulfonate, 14.0 parts of water) and a particle size of 2.8 mm. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 113.

[Example 45]
The pharmaceutical composition consists of 10.0 parts of ipphencarbazone (herbicidal active ingredient), fly ash balloon (average particle size 80-120 μm) (suspended carrier) 28.0 parts, 1.5 parts of Na dialkylsuccinate sulfonate, partial elimination. Na sulfonated lignin sulfonate 3.0 parts, polyacrylic acid Na 2.0 parts, carboxymethyl cellulose Na 2.0 parts, bentonite 10.0 parts, pearlite 20.0 parts, white carbon 15.0 parts, clay 8.5 parts ( Of these, the composition used for the slurry was 10.0 parts of ipphencarbazone, 1.0 part of Na dialkylsuccinate sulfonate, 14.0 parts of water), and the particle size was 3.0 mm, and the water surface was based on Example 35. A floating pesticide preparation was prepared. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 99.

[Example 46]
The composition of the preparation was 10.0 parts of ipphencarbazone (herbicidal active ingredient), ceramic balloon (average particle size 20 to 150 μm) (floating carrier) 28.0 parts, Na 3.0 part of alkylnaphthalene sulfonate, formaldehyde sulfonate. Condensate Na 3.0 parts, acrylic-vinyl sulfonic acid copolymer Na 2.0 parts, carboxymethyl cellulose Na 3.0 parts, bentonite 10.0 parts, diatomaceous soil 38.0 parts, clay 6.0 parts (of which used for slurry The composition was 10.0 parts of ipphencarbazone, 1.0 part of Na alkylnaphthalene sulfonate, 14.0 parts of water), and the particle size was 2.8 mm, and a water-floating pesticide preparation was prepared according to Example 35. did. The particle size of the obtained pharmaceutical product was 96% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.1, and the number of grains per 1 g was 108.

[Example 47]
The pharmaceutical composition consists of 10.0 parts of ipphencarbazone (herbicidal active ingredient), 2.0 parts of acrylonitrile resin balloon (average particle size 20-40 μm) (suspended carrier), 1.5 parts of Na dialkylsuccinate sulfonate, partial elimination. Na sulfonated lignin sulfonate 3.0 parts, acrylic acid-maleic acid copolymer Na 2.0 parts, carboxymethyl cellulose Na 2.0 parts, pearlite 10.0 parts, diatomaceous soil 61.5 parts, clay 8.0 parts (including slurry The composition used in the above was 10.0 parts of ipphencarbazone, 1.0 part of Na dialkylsuccinate sulfonate, 14.0 parts of water), a particle size of 3.0 mm, and water surface floating property according to Example 35. A pesticide preparation was prepared. The particle size of the obtained pharmaceutical product was 93% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 103.

[Example 48]
The composition of the preparation was 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 90-120 μm) (floating carrier) 25.0 parts, Na of alkylnaphthalene sulfonic acid 3.0 parts, alkylnaphthalene sulfonic acid. Formaldehyde condensate Na 3.0 parts, acrylic-vinyl sulfonic acid copolymer Na 2.0 parts, carboxymethyl cellulose Na 3.0 parts, bentonite 10.0 parts, pearlite 38.0 parts, clay 6.0 parts (of which used for slurry The composition was 10.0 parts of ipphencarbazone, 1.0 part of Na alkylnaphthalene sulfonate, 14.0 parts of water), and the particle size was 2.8 mm. Prepared. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 113.

[Example 49]
The pharmaceutical composition consists of 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 90-120 μm) (floating carrier) 28.0 parts, 1.5 parts of dialkylsuccinate sulfonic acid Na, naphthalene sulfonic acid. 3. Formaldehyde condensate Na 3.0 parts, acrylate-methacrylic acid copolymer Na 2.0 parts, carboxymethyl cellulose Na 3.0 parts, bentonite 10.0 parts, pearlite 25.0 parts, white carbon 10.0 parts, clay 7. 5 parts (of which the composition used for the slurry is 10.0 parts of ipphencarbazone, 1.0 part of Na dialkylsuccinate sulfonate, 14.0 parts of water) and the particle size is 3.0 mm, and conforms to Example 35. Then, a water-floating pesticide preparation was prepared. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.1, and the number of grains per 1 g was 96.

[Example 50]
The pharmaceutical composition consists of 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, Na 3.0 part of alkylnaphthalene sulfonate, partial desulfonatement. 3.0 parts of lignin sulfonic acid Na, 3.0 parts of acrylic-maleic acid copolymer Na, 2.0 parts of carboxymethyl cellulose Na, 45.0 parts of pearlite, 9.0 parts of clay (of which the composition used for the slurry is ipphencarba). A water-floating pesticide preparation was prepared according to Example 35 with 10.0 parts of zone, 1.0 part of Na alkylnaphthalene sulfonate, 14.0 parts of water) and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 94% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 97.

[Example 51]
The pharmaceutical composition consists of 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 90-120 μm) (suspended carrier) 28.0 parts, 1.5 parts of Na dialkylsuccinate sulfonate, alkylnaphthalene sulfone. 3.0 parts of acid formaldehyde condensate Na, 3.0 parts of polyacrylic acid Na, 3.0 parts of carboxymethyl cellulose Na, 48.0 parts of diatomaceous earth, 3.5 parts of clay (of which the composition used for the slurry is ipphencarbazone 10. 0 part, 1.0 part of Na dialkylsuccinate sulfonic acid, 14.0 parts of water), and the particle size was 2.8 mm, and a water-floating pesticide preparation was prepared according to Example 35. The particle size of the obtained pharmaceutical product was 97% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 90.

[Example 52]
12.0 parts of simethrin (herbicidal active ingredient), silas balloon (average particle size 70-90 μm) (floating carrier) 30.0 parts, Na of alkylnaphthalene sulfonate 3.0 parts, dextrin 5.0 parts, bentonite 10.0 38.0 parts of pearlite and 2.0 parts of clay were pulverized and mixed with a hammer mill (sample mill KIIW-1, manufactured by Dalton) to obtain a powder mixture. The obtained powder mixture was placed in a double-arm kneader (KDHJ, manufactured by Dalton) and kneaded for 15 minutes after water addition. Next, this hydrolyzed product was granulated by an extrusion granulator equipped with a basket-type screen having a pore size of 3.0 mm. The obtained granulated product was pre-dried, sized with a drum-type granulator, and dried with a fluidized bed dryer. This was sieved at 3.35 mm to 2.00 mm to obtain a water-floating pesticide preparation. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 93.

[Example 53]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), fly ash balloon (average particle size 80 to 120 μm) (floating carrier) 28.0 parts, 1.5 parts of dialkylsuccinate sulfonic acid Na, 3.0 parts of carboxymethyl cellulose. A water-floating pesticide preparation was prepared according to Example 50 with 43.0 parts of pearlite, 12.5 parts of clay, and a particle size of 2.8 mm. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 88.

[Example 54]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), 2.0 parts of acrylonitrile resin balloon (average particle size 20-40 μm) (floating carrier), 3.0 parts of Na alkylnaphthalene sulfonate, 2.0 parts of Na polyacrylate. A water-floating pesticide preparation was prepared according to Example 52 with 2.0 parts of Nacarboxymethylcellulose, 65.0 parts of pearlite, 14.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 87% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 97.

[Example 55]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), ceramic balloon (average particle size 20 to 150 μm) (suspended carrier) 28.0 parts, Na of alkylnaphthalene sulfonate 3.0 parts, Na of carboxymethyl cellulose 3.0 parts, The water-floating pesticide preparation was prepared according to Example 52 with 45.0 parts of diatomaceous earth, 9.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 93% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 96.

[Example 56]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), silas balloon (average particle size 70 to 90 μm) (floating carrier) 28.0 parts, 1.5 parts of dialkylsuccinate sulfonate Na, and acrylic acid-maleic acid. Example 52 with 2.0 parts of polymer Na, 3.0 parts of carboxymethyl cellulose Na, 10.0 parts of bentonite, 30.0 parts of pearlite, 8.0 parts of white carbon, 5.5 parts of clay, and 2.8 mm of particle size. A water-floating pesticide preparation was prepared according to the above. The particle size of the obtained pharmaceutical product was 96% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 108.

[Example 57]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), 28.0 parts of silas balloon (average particle size 90 to 120 μm) (suspended carrier), 3.0 parts of Na alkylnaphthalene sulfonate, acrylic-methacrylic acid copolymer. Na 2.0 parts, carboxymethyl cellulose Na 3.0 parts, diatomaceous earth 47.0 parts, clay 5.0 parts, particle size 2.8 mm were prepared, and a water-floating pesticide preparation was prepared according to Example 52. The particle size of the obtained pharmaceutical product was 87% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 95.

[Example 58]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 30.0 parts, 1.5 parts of dialkylsuccinate sulfonic acid Na, 3.0 parts of polyacrylic acid Na. A water-floating pesticide preparation was prepared according to Example 52 with 3.0 parts of Nacarboxymethylcellulose, 45.0 parts of diatomaceous earth, 5.5 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 97.

[Example 59]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 30.0 parts, Na 3.0 parts of alkylnaphthalene sulfonic acid, acrylic-maleic acid copolymer. Na 3.0 part, carboxymethyl cellulose Na 2.0 part, pearlite 46.0 part, clay 4.0 part, particle size 3.0 mm, and water floating pesticide preparation was prepared according to Example 52. The particle size of the obtained pharmaceutical product was 96% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 93.

[Example 60]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 30.0 parts, 1.5 parts of dialkylsuccinate sulfonic acid Na, acrylic acid-vinyl sulfonic acid. A water-floating pesticide preparation was prepared according to Example 52 with 2.0 parts of copolymer Na, 2.0 parts of carboxymethyl cellulose Na, 47.5 parts of pearlite, 5.0 parts of clay, and a particle size of 2.8 mm. .. The particle size of the obtained pharmaceutical product was 94% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 98.

[Example 61]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), silas balloon (average particle size 70 to 90 μm) (floating carrier) 30.0 parts, Na 3.0 parts of alkylnaphthalene sulfonic acid, and formaldehyde condensate of alkylnaphthalene sulfonic acid. Na 3.0 parts, acrylic-methacrylic acid copolymer Na 2.0 parts, carboxymethyl cellulose Na 2.0 parts, pearlite 40.0 parts, clay 8.0 parts, particle size 2.8 mm, conforming to Example 52. Prepared a water-floating pesticide preparation. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 108.

[Example 62]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), fly ash balloon (average particle size 80 to 120 μm) (floating carrier) 28.0 parts, 1.5 parts of Na dialkylsuccinate sulfonate, partially desulfonated lignin. Na sulfonate 3.0 parts, Na polyacrylate parts 3.0 parts, Carboxymethyl cellulose Na 2.0 parts, Bentnite 10.0 parts, Parlite 25.0 parts, White carbon 10.0 parts, Clay 5.5 parts, particle size formation The water-floating pesticide preparation was prepared according to Example 52 with a thickness of 3.0 mm. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 100.

[Example 63]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), ceramic balloon (average particle size 20 to 150 μm) (floating carrier) 30.0 parts, Na of alkylnaphthalene sulfonate 3.0 parts, formaldehyde condensate of naphthalene sulfonate Na3. .0 parts, acrylic-vinyl sulfonic acid copolymer Na 3.0 parts, carboxymethyl cellulose Na 2.0 parts, bentonite 10.0 parts, diatomaceous soil 30.0 parts, clay 7.0 parts, particle size 2.8 mm. A water-floating pesticide preparation was prepared according to Example 52. The particle size of the obtained pharmaceutical product was 95% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 97.

[Example 64]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), 2.0 parts of acrylonitrile resin balloon (average particle size 20-40 μm) (floating carrier), 1.5 parts of Na dialkylsuccinate sulfonate, and partially desulfonated lignin. Example 52 with 3.0 parts of Na sulfonate, 2.0 parts of Na acrylate-maleic acid copolymer, 2.0 parts of Na carboxymethyl cellulose, 67.5 parts of diatomaceous soil, 10.0 parts of clay, and 3.0 mm of particle size. A water-floating pesticide preparation was prepared according to the above. The particle size of the obtained pharmaceutical product was 94% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 96.

[Example 65]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 30.0 parts, Na 3.0 parts of alkylnaphthalene sulfonic acid, and formaldehyde condensate of alkylnaphthalene sulfonic acid. Na 3.0 parts, acrylic-vinyl sulfonic acid copolymer Na 3.0 parts, carboxymethyl cellulose Na 2.0 parts, bentonite 10.0 parts, pearlite 30.0 parts, clay 7.0 parts, particle size 2.8 mm. , A water-floating pesticide preparation was prepared according to Example 52. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 93.

[Example 66]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 30.0 parts, 1.5 parts of dialkylsuccinate sulfonic acid Na, naphthalene sulfonic acid formaldehyde condensate. Na 3.0 parts, acrylate-methacrylic acid copolymer Na 2.0 parts, carboxymethyl cellulose Na 2.0 parts, bentonite 10.0 parts, pearlite 20.0 parts, white carbon 15.0 parts, clay 4.5 parts, A water-floating pesticide preparation was prepared according to Example 52 with a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 101.

[Example 67]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 30.0 parts, Na 3.0 parts of alkylnaphthalene sulfonic acid, partially desulfonated lignin sulfonic acid. Na 3.0 parts, acrylic-maleic acid copolymer Na 3.0 parts, carboxymethyl cellulose Na 3.0 parts, pearlite 39.0 parts, clay 7.0 parts, particle size 3.0 mm, conforming to Example 52. Prepared a water-floating pesticide preparation. The particle size of the obtained pharmaceutical product was 93% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.1, and the number of grains per 1 g was 94.

[Example 68]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, 1.5 parts of dialkylsuccinate sulfonic acid Na, alkylnaphthalene sulfonic acid formaldehyde condensation. Product Na 3.0 parts, polyacrylate Na 2.0 parts, carboxymethyl cellulose Na 3.0 parts, diatomaceous soil 48.5 parts, clay 5.0 parts, particle size 2.8 mm, floating on the water surface according to Example 52 A sex pesticide preparation was prepared. The particle size of the obtained pharmaceutical product was 97% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 98.

[Example 69]
Ben Fresate 18.0 parts (herbivorous active ingredient), silas balloon (average particle size 70-90 μm) (floating carrier) 30.0 parts, alkylnaphthalene sulfonate Na 3.0 parts, dextrin 3.0 parts, polyvinyl alcohol 1. 0 parts, 5.0 parts of bentonite, 30.0 parts of pearlite, and 10.0 parts of clay were pulverized and mixed with a hammer mill (sample mill KIIW-1, manufactured by Dalton) to obtain a powder mixture. The obtained powder mixture was placed in a double-arm kneader (KDHJ, manufactured by Dalton) and kneaded for 15 minutes after water addition. Next, this hydrolyzed product was granulated by an extrusion granulator equipped with a basket-type screen having a pore size of 3.0 mm. The obtained granulated product was pre-dried, sized with a drum-type granulator, and dried with a fluidized bed dryer. This was sieved at 3.35 mm to 2.00 mm to obtain a water-floating pesticide preparation. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 93.

[Example 70]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), fly ash balloon (average particle size 80 to 120 μm) (floating carrier) 28.0 parts, 1.5 parts of dialkylsuccinate sulfonic acid Na, 2.0 parts of carboxymethyl cellulose. A water-floating pesticide preparation was prepared according to Example 50 with 45.5 parts of pearlite, 5.0 parts of clay, and a particle size of 2.8 mm. The particle size of the obtained pharmaceutical product was 87% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 83.

[Example 71]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), 2.0 parts of acrylonitrile resin balloon (average particle size 20-40 μm) (floating carrier), 3.0 parts of Naalkylnaphthalene sulfonate, 2.0 parts of Na polyacrylate. A water-floating pesticide preparation was prepared according to Example 69 with 2.0 parts of Nacarboxymethylcellulose, 63.0 parts of pearlite, 10.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 86.

[Example 72]
The pharmaceutical composition is 18.0 parts of benfresate (herbicidal active ingredient), ceramic balloon (average particle size 20 to 150 μm) (suspended carrier) 30.0 parts, alkylnaphthalene sulfonic acid Na 3.0 parts, carboxymethyl cellulose Na 3.0 parts, The water-floating pesticide preparation was prepared according to Example 69 with 39.0 parts of diatomaceous earth, 7.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 94% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 97.

[Example 73]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), silas balloon (average particle size 70 to 90 μm) (floating carrier) 28.0 parts, dialkylsuccinate sulfonate Na 1.5 parts, acrylic acid-maleic acid. The polymer Na 2.0 parts, carboxymethyl cellulose Na 3.0 parts, bentonite 10.0 parts, pearlite 25.0 parts, white carbon 7.5 parts, clay 5.0 parts, particle size 2.8 mm, Example 69. A water-floating pesticide preparation was prepared according to the above. The particle size of the obtained pharmaceutical product was 93% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 82.

[Example 74]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 30.0 parts, Na of alkylnaphthalene sulfonate 3.0 parts, acrylic-methacrylic acid copolymer. Na 2.0 part, carboxymethyl cellulose Na 2.0 part, diatomaceous earth 40.0 part, clay 5.0 part, particle size 2.8 mm were prepared, and a water floating pesticide preparation was prepared according to Example 69. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 85.

[Example 75]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 30.0 parts, dialkyl succinate sulfonic acid Na 1.5 parts, polyacrylic acid Na 3.0. A water-floating pesticide preparation was prepared according to Example 69 with 2.0 parts of Nacarboxymethylcellulose, 40.0 parts of diatomaceous earth, 5.5 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 80.

[Example 76]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 28.0 parts, Na of alkylnaphthalene sulfonate 3.0 parts, acrylic-maleic acid copolymer. Na 3.0 part, carboxymethyl cellulose Na 2.0 part, pearlite 38.0 part, clay 8.0 part, particle size 3.0 mm, and water floating pesticide preparation was prepared according to Example 69. The particle size of the obtained pharmaceutical product was 93% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 91.

[Example 77]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 25.0 parts, dialkyl succinate sulfonic acid Na 1.5 parts, acrylic acid-vinyl sulfonic acid. The copolymer Na 2.0 parts, carboxymethyl cellulose Na 2.0 parts, pearlite 46.5 parts, clay 5.0 parts, particle size 2.8 mm were prepared, and a water-floating pesticide preparation was prepared according to Example 69. .. The particle size of the obtained pharmaceutical product was 97% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.1, and the number of grains per 1 g was 79.

[Example 78]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), silas balloon (average particle size 70 to 90 μm) (floating carrier) 28.0 parts, Na of alkylnaphthalene sulfonic acid 3.0 parts, formaldehyde condensate of alkylnaphthalene sulfonic acid. Na 3.0 parts, acrylic-methacrylic acid copolymer Na 2.0 parts, carboxymethyl cellulose Na 2.0 parts, pearlite 39.0 parts, clay 5.0 parts, particle size 2.8 mm, conforming to Example 69. Prepared a water-floating pesticide preparation. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 75.

[Example 79]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), fly ash balloon (average particle size 80 to 120 μm) (floating carrier) 30.0 parts, dialkyl succinate sulfonate Na 1.5 parts, partially desulfonated lignin. Na sulfonate 3.0 parts, Na polyacrylate parts 2.0 parts, Carboxymethyl cellulose Na 2.0 parts, Bentnite 10.0 parts, Parlite 18.5 parts, White carbon 10.0 parts, Clay 5.0 parts, Particle size. The water-floating pesticide preparation was prepared according to Example 69 with a thickness of 3.0 mm. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 98.

[Example 80]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), ceramic balloon (average particle size 20 to 150 μm) (floating carrier) 30.0 parts, alkylnaphthalene sulfonic acid Na 3.0 parts, naphthalene sulfonic acid formaldehyde condensate Na3. .0 parts, acrylic-vinyl sulfonic acid copolymer Na 3.0 parts, carboxymethyl cellulose Na 2.0 parts, bentonite 10.0 parts, diatomaceous soil 28.0 parts, clay 4.0 parts, particle size 2.8 mm. A water-floating pesticide preparation was prepared according to Example 69. The particle size of the obtained pharmaceutical product was 97% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 89.

[Example 81]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), 2.0 parts of acrylonitrile resin balloon (average particle size 20-40 μm) (floating carrier), 1.5 parts of Na dialkylsuccinate sulfonate, and partially desulfonated lignin. Example 69 with 3.0 parts of Na sulfonate, 2.0 parts of Na acrylate-maleic acid copolymer, 3.0 parts of Na carboxymethyl cellulose, 60.5 parts of diatomaceous soil, 10.0 parts of clay, and 3.0 mm of particle size. A water-floating pesticide preparation was prepared according to the above. The particle size of the obtained pharmaceutical product was 95% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 86.

[Example 82]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 28.0 parts, Na of alkylnaphthalene sulfonic acid 3.0 parts, formaldehyde condensate of alkylnaphthalene sulfonic acid. Na 3.0 parts, acrylic-vinyl sulfonic acid copolymer Na 3.0 parts, carboxymethyl cellulose Na 3.0 parts, bentonite 10.0 parts, pearlite 28.0 parts, clay 4.0 parts, particle size 2.8 mm. , A water-floating pesticide preparation was prepared according to Example 69. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 98.

[Example 83]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 30.0 parts, dialkylsuccinate sulfonic acid Na 1.5 parts, naphthalene sulfonic acid formaldehyde condensate. Na 3.0 parts, acrylate-methacrylic acid copolymer Na 3.0 parts, carboxymethyl cellulose Na 3.0 parts, bentonite 10.0 parts, pearlite 15.0 parts, white carbon 12.0 parts, clay 4.5 parts, A water-floating pesticide preparation was prepared according to Example 69 with a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.1, and the number of grains per 1 g was 101.

[Example 84]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 28.0 parts, Na of alkylnaphthalene sulfonic acid 3.0 parts, partially desulfonated lignin sulfonic acid. Na 3.0 parts, acrylic-maleic acid copolymer Na 3.0 parts, carboxymethyl cellulose Na 3.0 parts, pearlite 37.0 parts, clay 5.0 parts, particle size 3.0 mm, conforming to Example 69. Prepared a water-floating pesticide preparation. The particle size of the obtained pharmaceutical product was 95% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 96.

[Example 85]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 30.0 parts, dialkylsuccinate sulfonic acid Na 1.5 parts, alkylnaphthalene sulfonic acid formaldehyde condensation. The product Na 3.0 parts, polyacrylic acid Na 3.0 parts, carboxymethyl cellulose Na 3.0 parts, diatomaceous soil 36.5 parts, clay 5.0 parts, particle size 2.8 mm, floating on the water surface according to Example 69. A sex pesticide preparation was prepared. The particle size of the obtained pharmaceutical product was 93% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 93.

[Comparative Example 1]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, Na alkylnaphthalene sulfonate 3.0 parts, Na carboxymethyl cellulose 2.0 parts, 40.0 parts of pearlite, 6.0 parts of clay, particle size of 3.0 mm, sieves at the time of sieving were 3.35 mm and 0.85 mm, and a water-floating pesticide preparation was prepared according to Example 1. did. The particle size of the obtained pharmaceutical product is 72% in the range of 2.80 to 1.70 mm (the rest is 28% below the particle size of 1.70 mm), and the major axis / minor axis ratio on the bottom surface is 1.2 grains per 1 g. The number was 179, and a preparation having many grains smaller than 1.70 mm in particle size was prepared.

[Comparative Example 2]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, Na of alkylnaphthalene sulfonate 3.0 parts, partially desulfonated lignin sulfonic acid. Example: Na 3.0 parts, carboxymethyl cellulose Na 2.0 parts, pearlite 36.0 parts, clay 7.0 parts, particle size 1.7 mm, sieves at the time of sieving were 2.00 mm and 0.85 mm sieves. A water-floating pesticide preparation was prepared according to 1. The particle size of the obtained pharmaceutical product is 5% in the range of 2.80 to 1.70 mm (the rest is 95% below the particle size of 1.70 mm), and the major axis / minor axis ratio on the bottom surface is 1.0 grains per 1 g. The number was 259, and a preparation having many small particles of 1.70 mm or less was prepared.

[Comparative Example 3]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, Na of alkylnaphthalene sulfonate 3.0 parts, formaldehyde condensate of alkylnaphthalene sulfonic acid. Example: Na 3.0 part, carboxymethyl cellulose Na 2.0 part, pearlite 35.0 part, clay 8.0 part, particle size 4.0 mm, sieves at the time of sieving were 4.76 mm and 2.36 mm. A water-floating pesticide preparation was prepared according to 1. The particle size of the obtained pharmaceutical product is 23% in the range of 2.80 to 1.70 mm (the rest is 77% above 2.80 mm), and the major axis / minor axis ratio on the bottom surface is 1.3 and the number of grains per 1 g. Was 36, and a preparation having a large number of grains larger than 2.80 mm was prepared.

[Comparative Example 4]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, Na of alkylnaphthalene sulfonate 3.0 parts, partially desulfonated lignin sulfonic acid. Na 3.0 parts, carboxymethyl cellulose Na 2.0 parts, pearlite 37.0 parts, clay 6.0 parts, particle size 3.0 mm, and the cross section is perfectly circular without passing through granulation with a drum granulator. The water-floating pesticide preparation was prepared by drying in this state. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.0, and the number of grains per 1 g was 112.

[Comparative Example 5]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, Naphthalene phthalene sulfonate 3.0 parts, Na carboxymethyl cellulose 2.0 parts, The pearlite is 38.0 parts, the clay is 8.0 parts, and the particle size is 3.0 mm. A floating pesticide preparation was prepared. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.6, and the number of grains per 1 g was 108.

[Comparative Example 6]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, Na of alkylnaphthalene sulfonate 3.0 parts, partially desulfonated lignin sulfonic acid. Na 3.0 parts, carboxymethyl cellulose Na 2.0 parts, pearlite 33.0 parts, clay 10.0 parts, particle size 3.0 mm, in addition to granulation with a drum granulator, up and down in a plastic bag The granulated product was sized so as to be tapped and dried to prepare a water-floating pesticide preparation. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.8, and the number of grains per 1 g was 119.

[Comparative Example 7]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), 3.0 parts of alkylnaphthalene sulfonate, 3.0 parts of partially desulfonated lignin sulfonate, 3.0 parts of carboxymethyl cellulose, 60.0 parts of pearlite, clay 7. A water-floating pesticide preparation was prepared according to Example 1 with 0.0 part and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 82% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 103.

[Comparative Example 8]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), 3.0 parts of alkylnaphthalene sulfonate, 3.0 parts of partially desulfonated lignin sulfonate, 3.0 parts of carboxymethyl cellulose, 18.0 parts of pearlite, clay 49. A water-floating pesticide preparation was prepared according to Example 1 with 0.0 part and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 43.

[Comparative Example 9]
2. The water-floating pesticide preparation was prepared according to Example 1 with 0 parts, 39.0 parts of pearlite, 6.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 108.

[Comparative Example 10]
2. The water-floating pesticide preparation was prepared according to Example 1 with 0 parts, 3.0 parts of carboxymethyl cellulose Na, 34.0 parts of pearlite, 8.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 98.

[Comparative Example 11]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, partially desulfonated lignin sulfonate Na 3.0 parts, alkylbenzene sulfonate Na3. The water-floating pesticide preparation was prepared according to Example 1 with 0.0 part, 2.0 parts of carboxymethyl cellulose Na, 38.0 parts of pearlite, 5.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 100.

[Comparative Example 12]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, alkylnaphthalene sulfonic acid formaldehyde condensate Na 3.0 parts, polyoxyethylene alkyl. A water-floating pesticide preparation was prepared according to Example 1 with 3.0 parts of ether, 2.0 parts of carboxymethyl cellulose Na, 36.0 parts of pearlite, 7.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 95.

[Comparative Example 13]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, polyoxyethylene arylphenyl ether 3.0 parts, carboxymethyl cellulose Na 3.0 parts. A water-floating pesticide preparation was prepared according to Example 1 with 39.0 parts of pearlite, 6.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 113.

[Comparative Example 14]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), 25.0 parts of silas balloon (average particle size 90 to 120 μm) (suspended carrier), 3.0 parts of alkylnaphthalene sulfonate Na, 3.0 parts of carboxymethyl cellulose Na, 47.0 parts of pearlite, 10.0 parts of clay, particle size of 3.0 mm, sieves at the time of sieving were 3.35 mm and 0.85 mm, and a water-floating pesticide preparation was prepared according to Example 18. did. The particle size of the obtained pharmaceutical product is 65% in the range of 2.80 to 1.70 mm (the rest is 35% below the particle size of 1.70 mm), and the major axis / minor axis ratio on the bottom surface is 1.2 grains per 1 g. The number was 195, and a preparation having many grains smaller than 1.70 mm in particle size was prepared.

[Comparative Example 15]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, Na 3.0 part of alkylnaphthalene sulfonic acid, partially desulfonated lignin sulfonic acid. Example: Na 3.0 part, carboxymethyl cellulose Na 3.0 part, pearlite 48.0 part, clay 6.0 part, particle size 1.7 mm, sieves at the time of sieving were 2.00 mm and 0.85 mm sieves. A water-floating pesticide preparation was prepared according to 18. The particle size of the obtained pharmaceutical product is 1% in the range of 2.80 to 1.70 mm (the rest is 99% below the particle size of 1.70 mm), and the major axis / minor axis ratio on the bottom surface is 1.0 grains per 1 g. The number was 283, and a preparation having many small particles of 1.70 mm or less was prepared.

[Comparative Example 16]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, Na 3.0 part of alkylnaphthalene sulfonic acid, and formaldehyde condensate of alkylnaphthalene sulfonic acid. Example: Na 3.0 parts, carboxymethyl cellulose Na 3.0 parts, pearlite 47.0 parts, clay 7.0 parts, particle size 4.0 mm, sieves at the time of sieving were 4.76 mm and 2.36 mm. A water-floating pesticide preparation was prepared according to 18. The particle size of the obtained pharmaceutical product is 15% in the range of 2.80 to 1.70 mm (the rest is 85% above 2.80 mm), and the major axis / minor axis ratio on the bottom surface is 1.2 and the number of grains per 1 g. Was 40, and a preparation having a large number of grains larger than 2.80 mm was prepared.

[Comparative Example 17]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, Na 3.0 part of alkylnaphthalene sulfonate, partially desulfonated lignin sulfonic acid. Na 3.0 parts, carboxymethyl cellulose Na 3.0 parts, pearlite 47.0 parts, clay 7.0 parts, particle size 3.0 mm, and the cross section is perfectly circular without passing through granulation with a drum granulator. The water-floating pesticide preparation was prepared by drying in this state. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.0, and the number of grains per 1 g was 105.

[Comparative Example 18]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), 25.0 parts of silas balloon (average particle size 90 to 120 μm) (floating carrier), 3.0 parts of alkylnaphthalene sulfonate Na, 3.0 parts of carboxymethyl cellulose Na, The pearlite is 51.0 parts, the clay is 6.0 parts, and the particle size is 3.0 mm. A floating pesticide preparation was prepared. The particle size of the obtained pharmaceutical product was 82% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.6, and the number of grains per 1 g was 96.

[Comparative Example 19]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 25.0 parts, Na 3.0 part of alkylnaphthalene sulfonate, partially desulfonated lignin sulfonic acid. Na 3.0 parts, carboxymethyl cellulose Na 3.0 parts, pearlite 47.0 parts, clay 7.0 parts, particle size 3.0 mm, in addition to granulation with a drum granulator, up and down in a plastic bag The granulated product was sized so as to be tapped and dried to prepare a water-floating pesticide preparation. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.8, and the number of grains per 1 g was 108.

[Comparative Example 20]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), 3.0 parts of alkylnaphthalene sulfonic acid Na, 3.0 parts of partially desulfonated lignin sulfonate Na, 3.0 parts of carboxymethyl cellulose Na, 69.0 parts of pearlite, clay 10. A water-floating pesticide preparation was prepared according to Example 18 with 0.0 part and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 93.

[Comparative Example 21]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), 3.0 parts of alkylnaphthalene sulfonate, 3.0 parts of partially desulfonated lignin sulfonate, 3.0 parts of carboxymethyl cellulose, 21.0 parts of pearlite, clay 58. A water-floating pesticide preparation was prepared according to Example 18 with 0.0 part and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 38.

[Comparative Example 22]
2. The water-floating pesticide preparation was prepared according to Example 18 with 0 parts, 51.0 parts of pearlite, 7.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 106.

[Comparative Example 23]
2. A water-floating pesticide preparation was prepared according to Example 18 with 0 parts, 2.0 parts of carboxymethyl cellulose Na, 48.0 parts of pearlite, 7.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 93.

[Comparative Example 24]
The pharmaceutical composition consists of 12.0 parts of pymetrodin (insecticidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, partially desulfonated lignin sulfonate Na 3.0 parts, alkylbenzene sulfonate Na3. The water-floating pesticide preparation was prepared according to Example 18 with 0.0 part, 2.0 parts of carboxymethyl cellulose Na, 46.0 parts of pearlite, 9.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 95.

[Comparative Example 25]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, alkylnaphthalene sulfonic acid formaldehyde condensate Na 3.0 parts, polyoxyethylene alkyl. A water-floating pesticide preparation was prepared according to Example 18 with 3.0 parts of ether, 3.0 parts of carboxymethyl cellulose Na, 50.0 parts of pearlite, 4.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 83.

[Comparative Example 26]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, polyoxyethylene arylphenyl ether 3.0 parts, carboxymethyl cellulose Na 3.0 parts. A water-floating pesticide preparation was prepared according to Example 18 with 49.0 parts of pearlite, 8.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.1, and the number of grains per 1 g was 99.

[Comparative Example 27]
The composition of the preparation was 10.0 parts of ipfencarbazone (herbicidal active ingredient), 25.0 parts of silas balloon (average particle size 90 to 120 μm) (suspended carrier), 3.0 parts of alkylnaphthalene sulfonate Na, carboxymethyl cellulose Na 2. 0 parts, pearlite 52.0 parts, clay 8.0 parts (of which the composition used for the slurry is 10.0 parts of ipphencarbazone, 1.0 part of Na alkylnaphthalene sulfonate, 14.0 parts of water), granulation The sieves having a diameter of 3.0 mm and the sieves at the time of sieving were 3.35 mm and 0.85 mm, and a water-floating pesticide preparation was prepared according to Example 35. The particle size of the obtained pharmaceutical product is 68% in the range of 2.80 to 1.70 mm (the rest is 32% below the particle size of 1.70 mm), and the major axis / minor axis ratio on the bottom surface is 1.2 grains per 1 g. The number was 175, and a preparation having many grains smaller than 1.70 mm in particle size was prepared.

[Comparative Example 28]
The composition of the preparation was 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 25.0 parts, Na 3.0 part of alkylnaphthalene sulfonate, partial desulfonatement. Na 3.0 parts of lignin sulfonate, 2.0 parts of Na carboxymethyl sulfonate, 48.0 parts of pearlite, 9.0 parts of clay (of which the composition used for the slurry is 10.0 parts of ipfencarbazone, Na 1. of alkylnaphthalene sulfonate. 0 part, 14.0 parts of water), the particle size was 1.7 mm, and the sieves at the time of sieving were 2.00 mm and 0.85 mm, and a water-floating pesticide preparation was prepared according to Example 35. The particle size of the obtained pharmaceutical product is 10% in the range of 2.80 to 1.70 mm (the rest is 90% below the particle size of 1.70 mm), and the major axis / minor axis ratio on the bottom surface is 1.0 grains per 1 g. The number was 354, and a preparation having many small particles of 1.70 mm or less was prepared.

[Comparative Example 29]
The pharmaceutical composition consists of 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 25.0 parts, Na of alkylnaphthalene sulfonic acid 3.0 parts, alkylnaphthalene sulfonic acid. Formaldehyde condensate Na 3.0 parts, carboxymethyl cellulose Na 2.0 parts, pearlite 51.0 parts, clay 6.0 parts (of which the composition used for the slurry is ipphencarbazone 10.0 parts, alkylnaphthalene sulfonate Na1. 0 part, 14.0 parts of water), the particle size was 4.0 mm, and the sieves at the time of sieving were 4.76 mm and 2.36 mm, and a water floating pesticide preparation was prepared according to Example 35. The particle size of the obtained pharmaceutical product is 38% in the range of 2.80 to 1.70 mm (the rest is 62% above 2.80 mm), and the major axis / minor axis ratio on the bottom surface is 1.2 and the number of grains per 1 g. Was 41, and a preparation having a large number of grains larger than 2.80 mm was prepared.

[Comparative Example 30]
The pharmaceutical composition consists of 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, Na 3.0 part of alkylnaphthalene sulfonate, partial desulfonatement. 3.0 parts of lignin sulfonate Na, 3.0 parts of carboxymethyl cellulose Na, 49.0 parts of pearlite, 7.0 parts of clay (of which the composition used for the slurry is 10.0 parts of ipphencarbazone, Na1 of alkylnaphthalene sulfonate. 0 part, 14.0 parts of water), particle size of 3.0 mm, and dried with the cross section on a perfect circle without passing through the sizing with a drum sizing machine to prepare a water-floating pesticide preparation. .. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.0, and the number of grains per 1 g was 98.

[Comparative Example 31]
2. 0 part, pearlite 52.0 part, clay 7.0 part (of which the composition used for the slurry is ipphencarbazone 10.0 part, alkylnaphthalene sulfonic acid Na 1.0 part, water 14.0 part), granulation The diameter was 3.0 mm, and in addition to the sizing with a drum sizing machine, the sizing was further struck up and down in a plastic bag and dried to prepare a water-floating pesticide preparation. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.6, and the number of grains per 1 g was 89.

[Comparative Example 32]
The pharmaceutical composition consists of 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, Na 3.0 part of alkylnaphthalene sulfonate, partial desulfonatement. 3.0 parts of lignin sulfonate Na, 3.0 parts of carboxymethyl cellulose Na, 49.0 parts of pearlite, 7.0 parts of clay (of which the composition used for the slurry is 10.0 parts of ipphencarbazone, Na1 of alkylnaphthalene sulfonate. 0 part, 14.0 parts of water), the particle size is 3.0 mm, and in addition to the sizing with a drum sizing machine, the sizing that is tapped up and down in a plastic bag is dried and floats on the water surface. A pesticide preparation was prepared. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.8, and the number of grains per 1 g was 83.

[Comparative Example 33]
The pharmaceutical composition consists of 10.0 parts of ipphencarbazone (herbicidal active ingredient), 3.0 parts of alkylnaphthalene sulfonic acid Na, 3.0 parts of partially desulfonated lignin sulfonic acid Na, 2.0 parts of carboxymethyl cellulose, and 65.0 parts of pearlite. , Clay 17.0 parts (of which the composition used for the slurry is 10.0 parts of ipphencarbazone, 1.0 part of Na alkylnaphthalene sulfonate, 14.0 parts of water), and the particle size is 3.0 mm. A water-floating pesticide preparation was prepared according to 35. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 96.

[Comparative Example 34]
The pharmaceutical composition consists of 10.0 parts of ipphencarbazone (herbicidal active ingredient), 3.0 parts of alkylnaphthalene sulfonic acid Na, 3.0 parts of partially desulfonated lignin sulfonic acid Na, 3.0 parts of carboxymethyl cellulose Na, and 30.0 parts of pearlite. , 51.0 parts of clay (of which the composition used for the slurry is 10.0 parts of ipphencarbazone, 1.0 part of Na alkylnaphthalene sulfonate, 14.0 parts of water), and the particle size is 3.0 mm. A water-floating pesticide preparation was prepared according to 35. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 33.

[Comparative Example 35]
The pharmaceutical composition consists of 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, partially desulfonated lignin sulfonate Na 3.0 parts, carboxy. Methyl cellulose Na 3.0 parts, pearlite 50.0 parts, clay 9.0 parts (of which the composition used for the slurry is ipphencarbazone 10.0 parts, partially desulfonated lignin sulfonate Na 1.0 parts, water 14. 0 part), the particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 35. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 105.

[Comparative Example 36]
The pharmaceutical composition consists of 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 90-120 μm) (suspended carrier) 25.0 parts, partially desulfonated Na lignin sulfonate 3.0 parts, alkyl. Na sulfate 3.0 parts, carboxymethyl cellulose Na 2.0 parts, pearlite 48.0 parts, clay 9.0 parts (of which the composition used for the slurry is ipphencarbazone 10.0 parts, partially desulfonated lignin sulfonate Na1 .0 parts, 14.0 parts of water), the particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 35. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.1, and the number of grains per 1 g was 90.

[Comparative Example 37]
The pharmaceutical composition consists of 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, partially desulfonated Na 3.0 parts of lignin sulfonate, alkylbenzene. Na sulfonate 3.0 parts, carboxymethyl cellulose Na 3.0 parts, pearlite 51.0 parts, clay 5.0 parts (of which the composition used for the slurry is ipphencarbazone 10.0 parts, partially desulfonated lignin sulfonic acid. Na 1.0 part, water 14.0 part), the particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 35. The particle size of the obtained pharmaceutical product was 82% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 110.

[Comparative Example 38]
The pharmaceutical composition consists of 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, alkylnaphthalene sulfonic acid formaldehyde condensate Na 3.0 parts, poly. Oxyethylene alkyl ether 3.0 parts, carboxymethyl cellulose Na 3.0 parts, pearlite 49.0 parts, clay 7.0 parts (of which the composition used for the slurry is ipphencarbazone 10.0 parts, polyoxyethylene alkyl ether 1.0 part, 14.0 parts of water), the particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 35. The particle size of the obtained pharmaceutical product was 87% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 99.

[Comparative Example 39]
The pharmaceutical composition consists of 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, polyoxyethylene arylphenyl ether 3.0 parts, carboxymethyl cellulose. Na 2.0 parts, pearlite 54.0 parts, clay 6.0 parts (of which the composition used for the slurry is ipphencarbazone 10.0 parts, polyoxyethylene arylphenyl ether 1.0 parts, water 14.0 parts. ), The particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 35. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 86.

[Comparative Example 40]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, Na of alkylnaphthalene sulfonate 3.0 parts, Na of carboxymethyl cellulose 3.0 parts, 51.0 parts of pearlite, 6.0 parts of clay, particle size of 3.0 mm, sieves at the time of sieving were 3.35 mm and 0.85 mm, and a water-floating pesticide preparation was prepared according to Example 52. did. The particle size of the obtained pharmaceutical product is 55% in the range of 2.80 to 1.70 mm (the rest is 45% below the particle size of 1.70 mm), and the major axis / minor axis ratio on the bottom surface is 1.4 grains per 1 g. The number was 203, and a preparation having many grains smaller than 1.70 mm in particle size was prepared.

[Comparative Example 41]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 25.0 parts, Na 3.0 part of alkylnaphthalene sulfonic acid, partially desulfonated lignin sulfonic acid. Example: Na 3.0 parts, carboxymethyl cellulose Na 2.0 parts, pearlite 47.0 parts, clay 8.0 parts, particle size 1.7 mm, sieves at the time of sieving were 2.00 mm and 0.85 mm sieves. A water-floating pesticide preparation was prepared according to 52. The particle size of the obtained pharmaceutical product is 8% in the range of 2.80 to 1.70 mm (the rest is 92% below the particle size of 1.70 mm), and the major axis / minor axis ratio on the bottom surface is 1.0. The number was 236, and a preparation having many small particles of 1.70 mm or less was prepared.

[Comparative Example 42]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 25.0 parts, Na 3.0 parts of alkylnaphthalene sulfonic acid, and formaldehyde condensate of alkylnaphthalene sulfonic acid. Example: Na 3.0 part, carboxymethyl cellulose Na 3.0 part, pearlite 49.0 part, clay 5.0 part, particle size 4.0 mm, sieves at the time of sieving were 4.76 mm and 2.36 mm. A water-floating pesticide preparation was prepared according to 52. The particle size of the obtained pharmaceutical product is 18% in the range of 2.80 to 1.70 mm (the rest is 82% above 2.80 mm), and the major axis / minor axis ratio on the bottom surface is 1.4, the number of grains per 1 g. Was 43, and a preparation having a large number of grains larger than 2.80 mm was prepared.

[Comparative Example 43]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 25.0 parts, Na 3.0 part of alkylnaphthalene sulfonic acid, partially desulfonated lignin sulfonic acid. Na 3.0 parts, carboxymethyl cellulose Na 2.0 parts, pearlite 49.0 parts, clay 6.0 parts, particle size 3.0 mm, and the cross section is perfectly circular without passing through granulation with a drum granulator. The water-floating pesticide preparation was prepared by drying in this state. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.0, and the number of grains per 1 g was 90.

[Comparative Example 44]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), 25.0 parts of silas balloon (average particle size 90 to 120 μm) (suspended carrier), 3.0 parts of alkylnaphthalene sulfonate Na, 3.0 parts of carboxymethyl cellulose Na, The pearlite is 51.0 parts, the clay is 6.0 parts, and the particle size is 3.0 mm. A floating pesticide preparation was prepared. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.6, and the number of grains per 1 g was 84.

[Comparative Example 45]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 25.0 parts, Na 3.0 part of alkylnaphthalene sulfonic acid, partially desulfonated lignin sulfonic acid. Na 3.0 parts, carboxymethyl cellulose Na 3.0 parts, pearlite 47.0 parts, clay 7.0 parts, particle size 3.0 mm, in addition to granulation with a drum granulator, up and down in a plastic bag The granulated product was sized so as to be tapped and dried to prepare a water-floating pesticide preparation. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.8, and the number of grains per 1 g was 95.

[Comparative Example 46]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), 3.0 parts of alkylnaphthalene sulfonate, 3.0 parts of partially desulfonated lignin sulfonate, 2.0 parts of carboxymethyl cellulose, 68.0 parts of pearlite, clay 12. A water-floating pesticide preparation was prepared according to Example 52 with 0.0 part and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.1, and the number of grains per 1 g was 99.

[Comparative Example 47]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), 3.0 parts of alkylnaphthalene sulfonic acid Na, 3.0 parts of partially desulfonated lignin sulfonate Na, 2.0 parts of carboxymethyl cellulose Na, 25.0 parts of pearlite, clay 55. A water-floating pesticide preparation was prepared according to Example 52 with 0.0 part and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 82% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 31.

[Comparative Example 48]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, partially desulfonated lignin sulfonate Na 3.0 parts, carboxymethyl cellulose Na 3. The water-floating pesticide preparation was prepared according to Example 52 with 0 parts, 49.0 parts of pearlite, 8.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 98.

[Comparative Example 49]
3. The water-floating pesticide preparation was prepared according to Example 52 with 0 parts, 3.0 parts of carboxymethyl cellulose Na, 48.0 parts of pearlite, 6.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 107.

[Comparative Example 50]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, partially desulfonated lignin sulfonate Na 3.0 parts, alkylbenzene sulfonate Na3. The water-floating pesticide preparation was prepared according to Example 52 with 0.0 part, 3.0 parts of carboxymethyl cellulose Na, 48.0 parts of pearlite, 6.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 110.

[Comparative Example 51]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, alkylnaphthalene sulfonic acid formaldehyde condensate Na 3.0 parts, polyoxyethylene alkyl. A water-floating pesticide preparation was prepared according to Example 52 with 3.0 parts of ether, 2.0 parts of carboxymethyl cellulose Na, 47.0 parts of pearlite, 8.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 106.

[Comparative Example 52]
The pharmaceutical composition consists of 12.0 parts of simethrin (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, polyoxyethylene arylphenyl ether 3.0 parts, carboxymethyl cellulose Na 2.0. A water-floating pesticide preparation was prepared according to Example 52 with 50.0 parts of pearlite, 8.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 114.

[Comparative Example 53]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 25.0 parts, alkylnaphthalene sulfonate Na 3.0 parts, carboxymethyl cellulose Na 2.0 parts, 46.0 parts of pearlite, 6.0 parts of clay, particle size of 3.0 mm, sieves at the time of sieving were 3.35 mm and 0.85 mm, and a water-floating pesticide preparation was prepared according to Example 69. did. The particle size of the obtained pharmaceutical product is 63% in the range of 2.80 to 1.70 mm (the rest is 37% below the particle size of 1.70 mm), and the major axis / minor axis ratio on the bottom surface is 1.4 grains per 1 g. The number was 188, and a preparation having many grains smaller than 1.70 mm in particle size was prepared.

[Comparative Example 54]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, alkylnaphthalene sulfonic acid Na 3.0 parts, partially desulfonated lignin sulfonic acid. Example: Na 3.0 part, carboxymethyl cellulose Na 3.0 part, pearlite 40.0 part, clay 8.0 part, particle size 1.7 mm, sieves at the time of sieving were 2.00 mm and 0.85 mm sieves. A water-floating pesticide preparation was prepared according to 69. The particle size of the obtained pharmaceutical product is 5% in the range of 2.80 to 1.70 mm (the rest is 95% below the particle size of 1.70 mm), and the major axis / minor axis ratio on the bottom surface is 1.0 grains per 1 g. The number was 313, and a preparation having many small particles of 1.70 mm or less was prepared.

[Comparative Example 55]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 25.0 parts, Na of alkylnaphthalene sulfonic acid 3.0 parts, formaldehyde condensate of alkylnaphthalene sulfonic acid. Example: Na 3.0 part, carboxymethyl cellulose Na 3.0 part, pearlite 40.0 part, clay 8.0 part, particle size 4.0 mm, sieves at the time of sieving were 4.76 mm and 2.36 mm. A water-floating pesticide preparation was prepared according to 69. The particle size of the obtained pharmaceutical product is 13% in the range of 2.80 to 1.70 mm (the rest is 87% above 2.80 mm), and the major axis / minor axis ratio on the bottom surface is 1.2 and the number of grains per 1 g. Was 39, and a preparation having a large number of grains larger than 2.80 mm was prepared.

[Comparative Example 56]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, alkylnaphthalene sulfonic acid Na 3.0 parts, partially desulfonated lignin sulfonic acid. Na 3.0 parts, carboxymethyl cellulose Na 3.0 parts, pearlite 38.0 parts, clay 10.0 parts, particle size 3.0 mm, and the cross section is perfectly circular without passing through granulation with a drum granulator. The water-floating pesticide preparation was prepared by drying in this state. The particle size of the obtained pharmaceutical product was 82% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.0, and the number of grains per 1 g was 108.

[Comparative Example 57]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, alkylnaphthalene sulfonic acid Na 3.0 parts, carboxymethyl cellulose Na 2.0 parts, The pearlite is 45.0 parts, the clay is 7.0 parts, and the particle size is 3.0 mm. A floating pesticide preparation was prepared. The particle size of the obtained pharmaceutical product was 82% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.6, and the number of grains per 1 g was 98.

[Comparative Example 58]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, alkylnaphthalene sulfonic acid Na 3.0 parts, partially desulfonated lignin sulfonic acid. Na 3.0 parts, carboxymethyl cellulose Na 2.0 parts, pearlite 39.0 parts, clay 10.0 parts, particle size 3.0 mm, in addition to granulation with a drum granulator, up and down in a plastic bag The granulated product was sized so as to be tapped and dried to prepare a water-floating pesticide preparation. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.8, and the number of grains per 1 g was 93.

[Comparative Example 59]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), 3.0 parts of alkylnaphthalene sulfonic acid Na, 3.0 parts of partially desulfonated lignin sulfonic acid Na, 2.0 parts of carboxymethyl cellulose Na, 67.0 parts of pearlite, clay 7. A water-floating pesticide preparation was prepared according to Example 69 with 0.0 part and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 102.

[Comparative Example 60]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), 3.0 parts of alkylnaphthalene sulfonic acid Na, 3.0 parts of partially desulfonated lignin sulfonate Na, 2.0 parts of carboxymethyl cellulose Na, 19.0 parts of pearlite, clay 55. A water-floating pesticide preparation was prepared according to Example 69 with 0.0 part and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.1, and the number of grains per 1 g was 35.

[Comparative Example 61]
2. The water-floating pesticide preparation was prepared according to Example 35 with 0 parts, 42.0 parts of pearlite, 9.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 96.

[Comparative Example 62]
2. The water-floating pesticide preparation was prepared according to Example 69 with 0 parts, 3.0 parts of carboxymethyl cellulose Na, 41.0 parts of pearlite, 7.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 93.

[Comparative Example 63]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, partially desulfonated lignin sulfonate Na 3.0 parts, alkylbenzene sulfonate Na3. The water-floating pesticide preparation was prepared according to Example 69 with 0.0 parts, 2.0 parts of Nacarboxymethylcellulose, 43.0 parts of pearlite, 6.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.1, and the number of grains per 1 g was 83.

[Comparative Example 64]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 25.0 parts, alkylnaphthalene sulfonic acid formaldehyde condensate Na 3.0 parts, polyoxyethylene alkyl. A water-floating pesticide preparation was prepared according to Example 69 with 3.0 parts of ether, 2.0 parts of carboxymethyl cellulose Na, 42.0 parts of pearlite, 7.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 82% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 78.

[Comparative Example 65]
The pharmaceutical composition consists of 18.0 parts of benfresate (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 25.0 parts, polyoxyethylene arylphenyl ether 3.0 parts, carboxymethyl cellulose Na 3.0 parts. A water-floating pesticide preparation was prepared according to Example 69 with 43.0 parts of pearlite, 8.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 88.

[Example 86]
Kasugamycin 24.0 parts (bactericidal active ingredient), polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2 carbon atoms, alkyl group: n-octyl, number of ester bonds: 1, cation: Na ⁺ ) 10.0 200 parts, propylene glycol 2.0 parts, alkylnaphthalene sulfonic acid Na 2.5 parts, methyl cellulose 3.0 parts, pearlite 25.0 parts, clay 8.5 parts with a hammer mill (sample mill KIIW-1, manufactured by Dalton). The mixture was pulverized and mixed to obtain a powder mixture. The obtained powder mixture and 25.0 parts of Shirasu balloon (average particle size 70 to 90 μm) (plankton carrier) were mixed with a dual arm kneader (KDHJ, manufactured by Dalton) for 10 minutes, then watered and kneaded for 15 minutes. Next, this hydrolyzed product was granulated by an extrusion granulator equipped with a basket-type screen having a pore size of 3.0 mm. The obtained granulated product was pre-dried, sized with a drum-type granulator, and dried with a fluidized bed dryer. This was sieved at 3.35 mm to 2.00 mm to obtain a water-floating pesticide preparation. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 113.

[Example 87]
The composition of the preparation was Kasugamycin 24.0 parts (bactericidal active ingredient), fly ash balloon (average particle size 80 to 120 μm) (floating carrier) 28.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: carbon number). 2, 3, Alkyl group: n-octyl, number of ester bonds: 2, cation: Na ⁺ ) 4.0 parts, propylene glycol 2.0 parts, alkylnaphthalene sulfonic acid Na 2.5 parts, acrylic acid-vinyl sulfonic acid A water-floating pesticide preparation was prepared according to Example 86 with 2.0 parts of the copolymer Na, 6.0 parts of dextrin, 20.0 parts of white carbon, 11.5 parts of bentonite, and a particle size of 2.8 mm. .. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 103.

[Example 88]
The composition of the preparation was 24.0 parts of kasugamycin (bactericidal active ingredient), ceramic balloon (average particle size 20 to 150 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2 carbon atoms). 3, Alkyl group: 2-ethylhexyl, number of ester bonds: 1, cation: Na ⁺ ) 6.0 parts, propylene glycol 1.5 parts, dialkyl succinate sulfonic acid Na 2.5 parts, polyacrylate Na 2.0 parts A water-floating pesticide preparation was prepared according to Example 86 with 3.0 parts of methyl cellulose, 25.0 parts of pearlite, 11.0 parts of bentonite, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.6, and the number of grains per 1 g was 175.

[Example 89]
The composition of the preparation was 24.0 parts of casgamycin (bactericidal active ingredient), 2.5 parts of acrylonitrile resin balloon (average particle size 20-40 μm) (suspended carrier), polyoxyalkylene alkyl ether phosphate salt (alkylene group: carbon number). 2, 3, Alkyl group: 2-ethylhexyl, number of ester bonds: 2, cation: Na ⁺ ) 12.0 parts, propylene glycol 3.0 parts, alkylnaphthalene sulfonic acid Na 2.5 parts, methyl cellulose 3.0 parts, A water-floating pesticide preparation was prepared according to Example 86 with 30.0 parts of white carbon, 23.0 parts of bentonite, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.5, and the number of grains per 1 g was 132.

[Example 90]
The composition of the preparation was 24.0 parts of kasugamycin (bactericidal active ingredient), ceramic balloon (average particle size 20 to 150 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2 carbon atoms). 4, Alkyl group: n-decyl, number of ester bonds: 1, cation: H ⁺ ) 10.0 parts, propylene glycol 2.0 parts, dialkyl succinate sulfonic acid Na 2.5 parts, polyacrylate Na 2.0 parts A water-floating pesticide preparation was prepared according to Example 86 with 6.0 parts of dextrin, 20.0 parts of pearlite, 8.5 parts of bentonite, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 115.

[Example 91]
The composition of the preparation was 24.0 parts of casgamycin (bactericidal active ingredient), 2.5 parts of acrylonitrile resin balloon (average particle size 20-40 μm) (suspended carrier), polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: carbon number). 2, 3, Alkyl group: n-decyl, number of ester bonds: 2, cation: H ⁺ ) 10.0 parts, propylene glycol 2.0 parts, alkylnaphthalene sulfonic acid Na 2.5 parts, acrylic acid-vinyl sulfonic acid A water-floating pesticide preparation was prepared according to Example 86 with 2.0 parts of the copolymer Na, 6.0 parts of dextrin, 30.0 parts of white carbon, 23.0 parts of bentonite, and a particle size of 2.8 mm. .. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 102.

[Example 92]
The composition of the preparation was Kasugamycin 24.0 parts (bactericidal active ingredient), fly ash balloon (average particle size 80-120 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: carbon number). 2, 3, Alkyl group: Isodecyl, Number of ester bonds: 1, Cation: K ⁺ ) 8.0 parts, Butylene glycol 2.5 parts, Dialkyl succinate sulfonic acid Na 2.5 parts, Acrylic acid-vinyl sulfonic acid A water-floating pesticide preparation was prepared according to Example 86 with 2.0 parts of polymer Na, 6.0 parts of dextrin, 17.0 parts of pearlite, 13.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 82% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 59.

[Example 93]
The composition of the preparation was Kasugamycin 24.0 parts (bactericidal active ingredient), silas balloon (average particle size 70 to 90 μm) (floating carrier) 28.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2 carbon atoms). , 3,4, alkyl group: isodecyl ester bonds: 2, ^cation: K +) 10.0 parts, 2.0 parts of propylene glycol, Na2.5 parts alkylnaphthalenesulfonate, acrylate - vinyl sulfonic acid copolymer The polymer Na was 2.0 parts, methyl cellulose was 3.0 parts, white carbon was 18.0 parts, bentonite was 10.5 parts, and the particle size was 2.8 mm, and a water-floating pesticide preparation was prepared according to Example 86. The particle size of the obtained pharmaceutical product was 87% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.1, and the number of grains per 1 g was 121.

[Example 94]
The composition of the preparation was Kasugamycin 24.0 parts (bactericidal active ingredient), fly ash balloon (average particle size 80-120 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate salt (alkylene group: carbon number). 2, 3, Alkyl group: 2-ethylhexyl, number of ester bonds: 1, cation: Na ⁺ ) 5.0 parts, polyoxyalkylene alkyl ether phosphate salt (alkylene group: 2, 3, alkyl group: 2-Ethylhexyl, number of ester bonds: 2, cation: Na ⁺ ) 5.0 parts, propylene glycol 2.5 parts, alkylnaphthalene sulfonate Na 2.5 parts, acrylic acid-methacrylate copolymer Na 2.0 parts, A water-floating pesticide preparation was prepared according to Example 86 with 3.0 parts of methyl cellulose, 20.0 parts of diatomaceous soil, 11.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 82% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.5, and the number of grains per 1 g was 135.

[Example 95]
The composition of the preparation was Kasugamycin 24.0 parts (bactericidal active ingredient), silas balloon (average particle size 70 to 90 μm) (floating carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2 carbon atoms). , Alkyl group: n-octyl, number of ester bonds: 1, cation: Na ⁺ ) 4.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2 or 3 carbon atoms, alkyl group: 2-ethylhexyl , Number of ester bonds: 1, Cation: Na ⁺ ) 4.0 parts, Polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2, 3, 4, alkyl group: isodecyl, number of ester bonds: 2, Cation: K ⁺ ) 4.0 parts, propylene glycol 2.0 parts, alkylnaphthalene sulfonate Na 2.5 parts, polyacrylic acid Na 3.0 parts, methyl cellulose 3.0 parts, pearlite 20.0 parts, clay 8. A water-floating pesticide preparation was prepared in accordance with Example 86 with 5 parts and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 82% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 127.

[Example 96]
The composition of the preparation was 24.0 parts of casgamycin (bactericidal active ingredient), ceramic balloon (average particle size 20 to 150 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2 carbon atoms). 3, 4, Alkyl group: n-octyl, number of ester bonds: 2, cation: Na ⁺ ) 6.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2, 3, alkyl group : 2-Ethylhexyl, number of ester bonds: 2, cation: Na ⁺ ) 6.0 parts, propylene glycol 2.5 parts, alkylnaphthalene sulfonic acid Na 2.5 parts, acrylic acid-vinyl sulfonic acid copolymer Na 2.0 A water-floating pesticide preparation was prepared according to Example 86 with 6.0 parts of dextrin, 20.0 parts of pearlite, 6.0 parts of bentonite, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 94% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 161.

[Example 97]
The composition of the preparation was Kasugamycin 24.0 parts (bactericidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 28.0 parts, polyoxyalkylene alkyl ether phosphate salt (alkylene group: 2 carbon atoms). 3, Alkyl group: n-decyl, number of ester bonds: 2, cation: H ⁺ ) 5.0 parts, polyoxyalkylene alkyl ether phosphate salt (alkylene group: 2, 3, alkyl group: isodecyl , Number of ester bonds: 1, Cation: K ⁺ ) 5.0 parts, propylene glycol 1.5 parts, dialkyl succinate sulfonate Na 2.5 parts, polyacrylic acid Na 2.5 parts, methyl cellulose 3.0 parts, diatomaceous soil A water-floating pesticide preparation was prepared according to Example 86 with 18.0 parts, 10.5 parts of bentonite, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 82% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 115.

[Example 98]
The composition of the preparation was 24.0 parts of kasugamycin (bactericidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2 carbon atoms). 4, Alkyl group: n-decyl, number of ester bonds: 1, cation: H ⁺ ) 8.0 parts, propylene glycol 2.0 parts, dialkyl succinate sulfonic acid Na 2.5 parts, acrylic acid-vinyl sulfonic acid The copolymer Na was 2.0 parts, methyl cellulose was 3.0 parts, pearlite was 25.0 parts, bentonite was 8.5 parts, and the particle size was 2.8 mm, and a water-floating pesticide preparation was prepared according to Example 86. The particle size of the obtained pharmaceutical product was 92% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 105.

[Example 99]
The composition of the preparation was 24.0 parts of casgamycin (bactericidal active ingredient), ceramic balloon (average particle size 20 to 150 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2 carbon atoms). 3, Alkyl group: Isodecyl, Number of ester bonds: 1, Cation: K ⁺ ) 4.0 parts, Polyoxyalkylene alkyl ether Phosphate ester salt (alkylene group: 2, 3, 4, Alkyl group: Isodecyl , Number of ester bonds: 2, Cation: K ⁺ ) 4.0 parts, propylene glycol 2.5 parts, Alkylnaphthalene sulfonic acid Na 2.5 parts, Naphthalene sulfonic acid formaldehyde condensate Na 5.0 parts, Polyacrylic acid Na 3. A water-floating pesticide preparation was prepared according to Example 86 with 0 part, 6.0 parts of dextrin, 20.0 parts of diatomaceous soil, 4.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 183.

[Example 100]
The composition of the preparation was Kasugamycin 24.0 parts (bactericidal active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 28.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2 carbon atoms). 3. Alkyl group: isodecyl, number of ester bonds: 1, cation: K ⁺ ) 10.0 parts, propylene glycol 2.0 parts, alkylnaphthalene sulfonic acid Na 2.5 parts, alkylnaphthalene sulfonic acid formaldehyde condensate Na 3. 0 part, acrylic acid-maleic acid copolymer Na 2.0 part, dextrin 6.0 part, pearlite 17.0 part, clay 5.5 part, particle size 3.0 mm, water surface according to Example 86 A floating pesticide preparation was prepared. The particle size of the obtained pharmaceutical product was 94% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 127.

[Example 101]
The composition of the preparation was 24.0 parts of casgamycin (bactericidal active ingredient), ceramic balloon (average particle size 20 to 150 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate salt (alkylene group: 2 carbon atoms). 3, Alkyl group: n-octyl, number of ester bonds: 2, cation: Na ⁺ ) 6.0 parts, polyoxyalkylene alkyl ether phosphate salt (alkylene group: 2, 3, alkyl group: n -Decil, number of ester bonds: 2, cation: H ⁺ ) 6.0 parts, propylene glycol 2.5 parts, dialkyl succinate sulfonate Na 2.5 parts, acrylic acid-methacrylic acid copolymer Na 2.0 parts, A water-floating pesticide preparation was prepared according to Example 86 with 3.0 parts of carboxymethyl cellulose Na, 20.0 parts of diatomaceous soil, 9.0 parts of bentonite, and a particle size of 2.8 mm. The particle size of the obtained pharmaceutical product was 82% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 118.

[Example 102]
The composition of the preparation was Kasugamycin 24.0 parts (bactericidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate salt (alkylene group: 2 carbon atoms). 3, Alkyl group: 2-ethylhexyl, number of ester bonds: 2, cation: Na ⁺ ) 4.0 parts, polyoxyalkylene alkyl ether phosphate salt (alkylene group: 2, 4, alkyl group: n -Decil, number of ester bonds: 1, cation: H ⁺ ) 4.0 parts, propylene glycol 3.0 parts, lignin sulfonate Na 3.0 parts, polyacrylic acid Na 2.0 parts, polyvinyl alcohol 3.0 parts, A water-floating pesticide preparation was prepared according to Example 86 with 20.0 parts of pearlite, 9.5 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 96% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 116.

[Example 103]
The composition of the preparation was 24.0 parts of casgamycin (bactericidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2 carbon atoms). 3, Alkyl group: n-octyl, number of ester bonds: 2, cation: Na ⁺ ) 5.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2, 3, alkyl group: n -Decil, number of ester bonds: 2, cation: H ⁺ ) 5.0 parts, alkylnaphthalene sulfonic acid Na 2.5 parts, alkylnaphthalene sulfonic acid formaldehyde condensate Na 3.0 parts, polyacrylic acid Na 2.0 parts, carboxy A water-floating pesticide preparation was prepared according to Example 86 with 3.0 parts of methyl cellulose Na, 12.5 parts of diatomaceous soil, 18.0 parts of bentonite, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 94% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 61.

[Example 104]
The pharmaceutical composition consists of 24.0 parts of kasugamycin (bactericidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, propylene glycol 3.0 parts, alkylnaphthalene sulfonate Na 2.5 parts, Naphthalene sulfonic acid formaldehyde condensate Na 3.0 parts, acrylic acid-vinyl sulfonic acid copolymer Na 2.0 parts, carboxymethyl cellulose Na 3.0 parts, diatomaceous soil 25.0 parts, bentonite 12.5 parts, particle size 3.0 mm Then, a water-floating pesticide preparation was prepared according to Example 86. The particle size of the obtained pharmaceutical product was 92% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 105.

[Example 105]
12.0 parts of pimetrodin (insecticidal active ingredient), polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2 carbon atoms, alkyl group: n-octyl, number of ester bonds: 1, cation: Na ⁺ ) 10.0 2.5 parts of propylene glycol, 2.5 parts of Na alkylnaphthalene sulfonate, 6.0 parts of dextrin, 27.0 parts of pearlite, 15.0 parts of bentonite with a hammer mill (sample mill KIIW-1, manufactured by Dalton). The mixture was pulverized and mixed to obtain a powder mixture. The obtained powder mixture and 25.0 parts of Shirasu balloon (average particle size 70 to 90 μm) (plankton carrier) were mixed with a dual arm kneader (KDHJ, manufactured by Dalton) for 10 minutes, then watered and kneaded for 15 minutes. Next, this hydrolyzed product was granulated by an extrusion granulator equipped with a basket-type screen having a pore size of 2.8 mm. The obtained granulated product was pre-dried, sized with a drum-type granulator, and dried with a fluidized bed dryer. This was sieved at 3.35 mm to 2.00 mm to obtain a water-floating pesticide preparation. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 138.

[Example 106]
The composition of the preparation was 12.0 parts of pimetrodin (insecticidal active ingredient), fly ash balloon (average particle size 80 to 120 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: carbon number). 2, 4, Alkyl group: n-octyl, number of ester bonds: 2, cation: Na ⁺ ) 4.0 parts, propylene glycol 2.0 parts, dialkyl succinate sulfonic acid Na 2.5 parts, acrylic acid-vinyl sulfone The acid copolymer Na was 1.5 parts, dextrin was 6.0 parts, diatomaceous soil was 28.0 parts, clay was 19.0 parts, and the particle size was 3.0 mm. .. The particle size of the obtained pharmaceutical product was 87% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 105.

[Example 107]
The composition of the preparation was 12.0 parts of pimetrodin (insecticidal active ingredient), fly ash balloon (average particle size 80 to 120 μm) (floating carrier) 30.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: carbon number). 2, 3, Alkyl group: 2-ethylhexyl, number of ester bonds: 1, cation: Na ⁺ ) 6.0 parts, propylene glycol 2.0 parts, dialkyl succinate sulfonic acid Na 2.5 parts, acrylic acid-vinyl sulfone An acid copolymer Na (2.0 parts), methyl cellulose (3.0 parts), diatomaceous soil (25, 0 parts), bentonite (17.5 parts), and particle size of 3.0 mm were used to prepare a water-floating pesticide preparation according to Example 105. .. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 182.

[Example 108]
The composition of the preparation was 12.0 parts of pimetrodin (insecticidal active ingredient), fly ash balloon (average particle size 80 to 120 μm) (floating carrier) 30.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: carbon number). 2. Alkyl group: 2-ethylhexyl, number of ester bonds: 2, cation: Na ⁺ ) 12.0 parts, hexylene glycol 2.5 parts, alkylnaphthalene sulfonate Na 2.5 parts, dextrin 7.0 parts, white A water-floating pesticide preparation was prepared according to Example 105 with 17.0 parts of carbon, 17.0 parts of bentonite, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 159.

[Example 109]
The composition of the preparation was 12.0 parts of pimetrodin (insecticidal active ingredient), ceramic balloon (average particle size 20 to 150 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2 carbon atoms). , Alkyl group: n-decyl, number of ester bonds: 1, cation: H ⁺ ) 10.0 parts, propylene glycol 2.0 parts, alkylnaphthalene sulfonic acid Na 2.5 parts, acrylic acid-methacrylate copolymer Na2 A water-floating pesticide preparation was prepared according to Example 105 with 0.0 parts, 3.0 parts of methyl cellulose, 25.0 parts of pearlite, 18.5 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 108.

[Example 110]
The composition of the preparation was 12.0 parts of pimetrodin (insecticidal active ingredient), 2.5 parts of acrylonitrile resin balloon (average particle size 20-40 μm) (suspended carrier), polyoxyalkylene alkyl ether phosphate salt (alkylene group: carbon number). 2, 3, 4, Alkyl group: n-decyl, number of ester bonds: 2, cation: H ⁺ ) 10.0 parts, propylene glycol 2.5 parts, dialkyl succinate sulfonate Na 2.5 parts, dextrin 6. A water-floating pesticide preparation was prepared according to Example 105 with 0 parts, 35.0 parts of diatomaceous soil, 29.5 parts of bentonite, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 125.

[Example 111]
The composition of the preparation was 12.0 parts of pymetrodin (insecticidal active ingredient), 30.0 parts of ceramic balloon (average particle size 20 to 150 μm) (suspended carrier), polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2 carbon atoms). , Alkyl group: isodecyl, number of ester bonds: 1, cation: K ⁺ ) 10.0 parts, propylene glycol 2.5 parts, alkylnaphthalene sulfonic acid Na 2.5 parts, acrylic acid-methacrylic acid copolymer Na 2.0 A water-floating pesticide preparation was prepared according to Example 105 with 3.0 parts of methyl cellulose, 23.0 parts of white carbon, 15.0 parts of clay, and a particle size of 2.8 mm. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.1, and the number of grains per 1 g was 113.

[Example 112]
The composition of the preparation was 12.0 parts of pimetrodin (insecticidal active ingredient), silas balloon (average particle size 70 to 90 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2 carbon atoms). , Alkyl group: isodecyl, number of ester bonds: 2, cation: K ⁺ ) 10.0 parts, propylene glycol 2.0 parts, dialkyl succinate sulfonic acid Na 2.5 parts, polyacrylate Na 1.0 parts, methyl cellulose 3 A water-floating pesticide preparation was prepared according to Example 105 with 0.0 parts, 25.0 parts of diatomaceous soil, 19.5 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 87% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 113.

[Example 113]
The composition of the preparation was 12.0 parts of pimetrodin (insecticidal active ingredient), fly ash balloon (average particle size 80 to 120 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate salt (alkylene group: carbon number). 2, 3, Alkyl group: 2-ethylhexyl, number of ester bonds: 1, cation: Na ⁺ ) 5.0 parts, polyoxyalkylene alkyl ether phosphate salt (alkylene group: 2 carbon atoms, alkyl group: 2- Ethylhexyl, number of ester bonds: 2, cation: Na ⁺ ) 5.0 parts, propylene glycol 2.5 parts, alkylnaphthalene sulfonate Na 2.5 parts, acrylic acid-methacrylic acid copolymer Na 3.0 parts, methyl cellulose 3 A water-floating pesticide preparation was prepared according to Example 105 with 0.0 parts, 25.0 parts of diatomaceous soil, 17.0 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.1, and the number of grains per 1 g was 124.

[Example 114]
The composition of the preparation was 12.0 parts of pimetrodin (insecticidal active ingredient), 30.0 parts of ceramic balloon (average particle size 20 to 150 μm) (suspended carrier), polyoxyalkylene alkyl ether phosphate salt (alkylene group: 2 carbon atoms). , Alkyl group: n-octyl, number of ester bonds: 1, cation: Na ⁺ ) 4.0 parts, polyoxyalkylene alkyl ether phosphate salt (alkylene group: 2 or 3 carbon atoms, alkyl group: 2-ethylhexyl , Number of ester bonds: 1, Cation: Na ⁺ ) 4.0 parts, propylene glycol 2.0 parts, Alkylnaphthalene sulfonic acid Na 2.5 parts, Acrylic acid-maleic acid copolymer Na 3.0 parts, Methyl cellulose 3. A water-floating pesticide preparation was prepared according to Example 105 with 0 parts, 23.0 parts of white carbon, 17.5 parts of bentonite, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.6, and the number of grains per 1 g was 105.

[Example 115]
The composition of the preparation was 12.0 parts of pimetrodin (insecticidal active ingredient), 2.5 parts of acrylonitrile resin balloon (average particle size 20-40 μm) (suspended carrier), polyoxyalkylene alkyl ether phosphate salt (alkylene group: carbon number). 2, 4, Alkyl group: n-octyl, number of ester bonds: 2, cation: Na ⁺ ) 6.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2, 3, alkyl group: 2-Ethylhexyl, number of ester bonds: 1, cation: Na ⁺ ) 6.0 parts, propylene glycol 3.0 parts, dialkyl succinate sulfonic acid Na 2.5 parts, acrylic acid-vinyl sulfonic acid copolymer Na 1.5 parts A water-floating pesticide preparation was prepared according to Example 105 with 6.0 parts of dextrin, 30.0 parts of pearlite, 30.5 parts of bentonite, and a particle size of 2.8 mm. The particle size of the obtained pharmaceutical product was 94% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 95.

[Example 116]
The composition of the preparation was 12.0 parts of pimetrodin (insecticidal active ingredient), 28.0 parts of silas balloon (average particle size 90 to 120 μm) (suspended carrier), polyoxyalkylene alkyl ether phosphate salt (alkylene group: 2 carbon atoms). 3, 4, Alkyl group: n-decyl, number of ester bonds: 2, cation: H ⁺ ) 10.0 parts, propylene glycol 1.5 parts, alkylnaphthalene sulfonic acid Na 2.5 parts, polyacrylic acid Na 2. A water-floating pesticide preparation was prepared according to Example 105 with 0 parts, 3.0 parts of methyl cellulose, 22.0 parts of diatomaceous soil, 19.0 parts of bentonite, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 93.

[Example 117]
The composition of the preparation was 12.0 parts of pimetrodin (insecticidal active ingredient), 28.0 parts of silas balloon (average particle size 90 to 120 μm) (suspended carrier), polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2 carbon atoms). 4, Alkyl group: n-octyl, number of ester bonds: 2, cation: Na ⁺ ) 4.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: carbon number 2, alkyl group: 2-ethylhexyl , Number of ester bonds: 2, Cation: Na ⁺ ) 4.0 parts, propylene glycol 1.5 parts, Dialkyl succinate sulfonic acid Na 2.5 parts, Acrylic acid-vinyl sulfonic acid copolymer Na 2.0 parts, Methyl cellulose The composition was 3.0 parts, 22.0 parts of diatomaceous soil, 21.0 parts of clay, and a particle size of 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 105. The particle size of the obtained pharmaceutical product was 97% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 109.

[Example 118]
The composition of the preparation was 12.0 parts of pimetrodin (insecticidal active ingredient), ceramic balloon (average particle size 20 to 150 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2 carbon atoms). 3, 4, Alkyl group: n-decyl, number of ester bonds: 2, cation: H ⁺ ) 12.0 parts, propylene glycol 3.0 parts, alkylnaphthalene sulfonate Na 2.5 parts, alkylnaphthalene sulfonate formaldehyde Condensate Na 3.0 parts, polyacrylate Na 3.0 parts, dextrin 6.0 parts, pearlite 25.0 parts, bentonite 8.5 parts, particle size 2.8 mm, floating on the water surface according to Example 105 A sex pesticide preparation was prepared. The particle size of the obtained pharmaceutical product was 82% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.1, and the number of grains per 1 g was 111.

[Example 119]
The composition of the preparation was 12.0 parts of pimetrodin (insecticidal active ingredient), 25.0 parts of silas balloon (average particle size 90 to 120 μm) (suspended carrier), polyoxyalkylene alkyl ether phosphate salt (alkylene group: 2 carbon atoms). 3, Alkyl group: 2-ethylhexyl, number of ester bonds: 1, cation: Na ⁺ ) 5.0 parts, polyoxyalkylene alkyl ether phosphate salt (alkylene group: 2 carbon atoms, alkyl group: n-decyl) , Number of ester bonds: 1, Cation: H ⁺ ) 5.0 parts, propylene glycol 1.5 parts, Alkylnaphthalene sulfonic acid Na 2.5 parts, Naphthalene sulfonic acid formaldehyde condensate Na 3.0 parts, Acrylic acid-methacrylic acid A water-floating pesticide preparation was prepared according to Example 105 with 2.5 parts of the copolymer Na, 3.0 parts of methyl cellulose, 25.0 parts of pearlite, 15.5 parts of clay, and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 96% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.1, and the number of grains per 1 g was 128.

[Example 120]
The composition of the preparation was 12.0 parts of pimetrodin (insecticidal active ingredient), 25.0 parts of silas balloon (average particle size 70 to 90 μm) (suspended carrier), polyoxyalkylene alkyl ether phosphate salt (alkylene group: 2 carbon atoms). , Alkyl group: n-octyl, number of ester bonds: 1, cation: Na ⁺ ) 10.0 parts, propylene glycol 2.0 parts, dialkyl succinate sulfonic acid Na 2.5 parts, acrylic acid-vinyl sulfonic acid co-weight The combined Na was 2.0 parts, carboxymethyl cellulose Na was 2.0 parts, white carbon was 25.0 parts, bentonite was 19.5 parts, and the particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 105. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 110.

[Example 121]
The composition of the preparation was 12.0 parts of pymetrodin (insecticidal active ingredient), 25.0 parts of silas balloon (average particle size 90 to 120 μm) (suspended carrier), polyoxyalkylene alkyl ether phosphate salt (alkylene group: 2 carbon atoms). 4, Alkyl group: n-octyl, number of ester bonds: 2, cation: Na ⁺ ) 10.0 parts, propylene glycol 2.5 parts, alkylnaphthalene sulfonic acid Na 2.5 parts, lignin sulfonate Na 2.5 parts , 2.0 parts of Na polyacrylate, 2.0 parts of polyvinyl alcohol, 26.0 parts of pearlite, 15.5 parts of bentonite, and a particle size of 2.8 mm, and a water-floating pesticide preparation was prepared according to Example 105. did. The particle size of the obtained pharmaceutical product was 97% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 119.

[Example 122]
The composition of the preparation was 12.0 parts of pimetrodin (insecticidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2 carbon atoms). 3, Alkyl group: 2-ethylhexyl, number of ester bonds: 1, cation: Na ⁺ ) 10.0 parts, alkylnaphthalene sulfonic acid Na 2.5 parts, alkylnaphthalene sulfonic acid formaldehyde condensate Na 2.5 parts, polyacrylic 2.0 parts of sodium acid, 3.0 parts of sodium carboxymethyl cellulose, 23.0 parts of pearlite, 15.0 parts of bentonite, 5.0 parts of clay, and a particle size of 3.0 mm were used. The formulation was prepared. The particle size of the obtained pharmaceutical product was 93% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 102.

[Example 123]
The pharmaceutical composition consists of 12.0 parts of pimetrodin (insecticidal active ingredient), 25.0 parts of silas balloon (average particle size 90 to 120 μm) (suspended carrier), 3.0 parts of propylene glycol, 2.5 parts of Na alkylnaphthalene sulfonate, Naphthalene sulfonic acid formaldehyde condensate Na 2.5 parts, acrylic acid-vinyl sulfonic acid copolymer Na 3.0 parts, carboxymethyl cellulose Na 3.0 parts, pearlite 26.0 parts, bentonite 10.0 parts, clay 13.0 parts, A water-floating pesticide preparation was prepared according to Example 105 with a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 91% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 79.

[Example 124]
After mixing 10.0 parts of ipfencarbazone (herbicidal active ingredient), 1.0 part of Naalkylnaphthalene sulfonate, and 14.0 parts of water, the average particle size becomes 1.0 μm with Dynomil (manufactured by Symmulenterprises). Wet pulverization to obtain a slurry. In addition, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2, 3, alkyl group: n-octyl, number of ester bonds: 1, cation: H ⁺ ) 8.0 parts, propylene glycol 2.0 Parts, 1.5 parts of Na alkylnaphthalene sulfonate, 3.0 parts of methyl cellulose, 29.0 parts of pearlite, and 17.5 parts of bentonite are pulverized and mixed with a hammer mill (sample mill KIIW-1, manufactured by Dalton), and a powder mixture is prepared. Got 28.0 parts of the slurry, powder mixture and shirasu balloon (average particle size 70 to 90 μm) (plankton carrier) were mixed with a double-arm kneader (KDHJ, manufactured by Dalton) for 10 minutes, then watered and kneaded for 15 minutes. Next, this hydrolyzed product was granulated by an extrusion granulator equipped with a basket-type screen having a pore size of 3.0 mm. The obtained granulated product was pre-dried, sized with a drum-type granulator, and dried with a fluidized bed dryer. This was sieved at 3.35 mm to 2.00 mm to obtain a water-floating pesticide preparation. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 132.

[Example 125]
The composition of the preparation was 10.0 parts of ipphencarbazone (herbicidal active ingredient), ceramic balloon (average particle size 20 to 150 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate salt (alkylene group:). Carbon number 2, 4, alkyl group: n-octyl, number of ester bonds: 2, cation: H ⁺ ) 4.0 parts, propylene glycol 1.5 parts, dialkyl succinate sulfonic acid Na 2.5 parts, acrylic acid- 2.0 parts of methacrylic acid copolymer Na, 6.0 parts of dextrin, 30.0 parts of pearlite, 19.0 parts of clay (of which the composition used for the slurry is 10.0 parts of ipphencarbazone, dialkylsuccinate sulfonic acid. Na 1.0 part, water 14.0 part), the particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 124. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 102.

[Example 126]
The composition of the preparation is 10.0 parts of ipphencarbazone (herbicidal active ingredient), fly ash balloon (average particle size 20 to 150 μm) (floating carrier) 30.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group). : 2,4 carbon atoms, alkyl group: 2-ethylhexyl, number of ester bonds: 1, cation: Na ⁺ ) 6.0 parts, propylene glycol 3.0 parts, dialkyl succinate sulfonic acid Na 2.5 parts, acrylic acid -Vinyl sulfonic acid copolymer Na 2.0 parts, methyl cellulose 3.0 parts, pearlite 27.0 parts, clay 16.5 parts (of which the composition used for the slurry is ipphencarbazone 10.0 parts, dialkylsuccinate Na sulfonate (1.0 part), water (14.0 part), and a particle size of 3.0 mm were used to prepare a water-floating pesticide preparation according to Example 124. The particle size of the obtained pharmaceutical product was 87% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 105.

[Example 127]
The composition of the preparation is 10.0 parts of ipphencarbazone (herbicidal active ingredient), 2.5 parts of acrylonitrile resin balloon (average particle size 20-40 μm) (floating carrier), polyoxyalkylene alkyl ether phosphate salt (alkylene group). : 2 carbon atoms, alkyl group: 2-ethylhexyl, number of ester bonds: 2, cation: Na ⁺ ) 10.0 parts, propylene glycol 2.0 parts, alkylnaphthalene sulfonic acid Na 2.5 parts, acrylic acid-vinyl sulfonate Acid copolymer Na 2.0 parts, methyl cellulose 3.0 parts, pearlite 40.0 parts, bentonite 30.0 parts (of which the composition used for the slurry is ipphencarbazone 10.0 parts, alkylnaphthalene sulfonic acid Na 1. 0 part, 14.0 parts of water), the particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 124. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 118.

[Example 128]
The composition of the preparation was 10.0 parts of ipphencarbazone (herbicidal active ingredient), ceramic balloon (average particle size 20 to 150 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate salt (alkylene group:). Carbon number 2, 4, alkyl group: n-decyl, number of ester bonds: 1, cation: Na ⁺ ) 8.0 parts, butylene glycol 2.0 parts, alkylnaphthalene sulfonic acid Na 2.5 parts, acrylic acid-maleine Acid copolymer Na 2.0 parts, dextrin 6.0 parts, diatomaceous soil 26.0 parts, bentonite 18.5 parts (of which the composition used for the slurry is ipphencarbazone 10.0 parts, alkylnaphthalene sulfonate Na1. 0 part, 14.0 parts of water), the particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 124. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 99.

[Example 129]
The composition of the preparation is 10.0 parts of ipphencarbazone (herbicidal active ingredient), fly ash balloon (average particle size 80-120 μm) (floating carrier) 30.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group). : 2,4 carbon atoms, alkyl group: n-decyl, number of ester bonds: 2, cation: Na ⁺ ) 12.0 parts, propylene glycol 3.0 parts, alkylnaphthalene sulfonic acid Na 2.5 parts, methyl cellulose 3. 0 parts, 26.0 parts of diatomaceous soil, 13.5 parts of clay (of which 10.0 parts of ipphencarbazone, 1.0 part of Na alkylnaphthalene sulfonate, 14.0 parts of water), granulation The diameter was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 124. The particle size of the obtained pharmaceutical product was 87% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.5, and the number of grains per 1 g was 143.

[Example 130]
The composition of the preparation was 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 70 to 90 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group:). Carbon number 2, 3, 4, alkyl group: isodecyl, number of ester bonds: 1, cation: K ⁺ ) 12.0 parts, propylene glycol 2.5 parts, dialkyl succinate sulfonic acid Na 2.5 parts, polyacrylic acid 2.0 parts of Na, 6.0 parts of dextrin, 25.0 parts of white carbon, 15.0 parts of bentonite (of which the composition used for the slurry is 10.0 parts of ipphencarbazone, 1.0 part of Na dialkylsuccinate sulfonate). , 14.0 parts of water), the particle size was 2.8 mm, and a water-floating pesticide preparation was prepared according to Example 124. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 85.

[Example 131]
The composition of the preparation was 10.0 parts of ipphencarbazone (herbicidal active ingredient), fly ash balloon (average particle size 80 to 120 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate salt (alkylene group). : 2,4 carbon atoms, alkyl group: isodecyl, number of ester bonds: 2, cation: K ⁺ ) 10.0 parts, propylene glycol 3.0 parts, alkylnaphthalene sulfonic acid Na 2.5 parts, acrylic acid-methacrylic acid Copolymer Na 2.0 parts, dextrin 6.0 parts, diatomaceous soil 25.0 parts, bentonite 16.5 parts (of which the composition used for the slurry is ipphencarbazone 10.0 parts, alkylnaphthalene sulfonate Na 1.0 part. , 14.0 parts of water), and the particle size was 2.8 mm, and a water-floating pesticide preparation was prepared according to Example 124. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.6, and the number of grains per 1 g was 180.

[Example 132]
The composition of the preparation was 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 70 to 90 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group:). Carbon number 2, 4, alkyl group: 2-ethylhexyl, number of ester bonds: 1, cation: Na ⁺ ) 6.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: carbon number 2, alkyl group: 2-Ethylhexyl, number of ester bonds: 2, cation: Na ⁺ ) 6.0 parts, propylene glycol 2.5 parts, alkylnaphthalene sulfonic acid Na 2.5 parts, acrylic acid-vinyl sulfonic acid copolymer Na 2.0 parts , Methyl cellulose 3.0 parts, pearlite 25.0 parts, clay 18.0 parts (of which the composition used for the slurry is ipfencarbazone 10.0 parts, alkylnaphthalene sulfonate Na 1.0 parts, water 14.0 parts. ), The particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 124. The particle size of the obtained pharmaceutical product was 82% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.1, and the number of grains per 1 g was 103.

[Example 133]
The composition of the preparation was 10.0 parts of ipphencarbazone (herbicidal active ingredient), ceramic balloon (average particle size 20 to 150 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group:). Carbon number 2, 3, alkyl group: n-octyl, number of ester bonds: 1, cation: H ⁺ ) 3.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: carbon number 2, 4, alkyl Group: 2-ethylhexyl, number of ester bonds: 1, cation: Na ⁺ ) 3.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2 or 4 carbon atoms, alkyl group: isodecyl, number of ester bonds : 2, Cation: K ⁺ ) 3.0 parts, propylene glycol 3.0 parts, alkylnaphthalene sulfonate Na 2.5 parts, acrylic acid-methacrylic acid copolymer Na 2.5 parts, methyl cellulose 3.0 parts, white 2.5.0 parts of carbon, 20.0 parts of bentonite (of which 10.0 parts of ipphencarbazone, 1.0 part of Na alkylnaphthalene sulfonate, 14.0 parts of water), particle size. The thickness was set to 0 mm, and a water-floating pesticide preparation was prepared according to Example 124. The particle size of the obtained pharmaceutical product was 82% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 93.

[Example 134]
The composition of the preparation was 10.0 parts of ipphencarbazone (herbicidal active ingredient), ceramic balloon (average particle size 20 to 150 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group:). Carbon number 2, 4, alkyl group: n-decyl, number of ester bonds: 1, cation: Na ⁺ ) 8.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: carbon number 2, 4, alkyl Group: n-decyl, number of ester bonds: 2, cation: Na ⁺ ) 4.0 parts, propylene glycol 2.0 parts, dialkyl succinate sulfonic acid Na 2.5 parts, polyacrylic acid Na 2.0 parts, dextrin 6 .0 parts, pearlite 25.0 parts, clay 15.5 parts (of which the composition used for the slurry is 10.0 parts of ipphencarbazone, 1.0 part of Na dialkylsuccinate sulfonate, 14.0 parts of water), A water-floating pesticide preparation was prepared according to Example 124 with a particle size of 2.8 mm. The particle size of the obtained pharmaceutical product was 95% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 108.

[Example 135]
The composition of the preparation was 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group:). Carbon number 2, 3, 4, alkyl group: isodecyl, number of ester bonds: 1, cation: K ⁺ ) 10.0 parts, propylene glycol 2.0 parts, alkylnaphthalene sulfonic acid Na 2.5 parts, acrylic acid-maleine Acid copolymer Na 2.0 parts, dextrin 6.0 parts, diatomaceous soil 25.0 parts, bentonite 17.5 parts (of which the composition used for the slurry is ipphencarbazone 10.0 parts, alkylnaphthalene sulfonate Na1. 0 part, 14.0 parts of water), the particle size was 2.8 mm, and a water-floating pesticide preparation was prepared according to Example 124. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 117.

[Example 136]
The composition of the preparation was 10.0 parts of ipphencarbazone (herbicidal active ingredient), 30.0 parts of silas balloon (average particle size 90 to 120 μm) (suspended carrier), polyoxyalkylene alkyl ether phosphate salt (alkylene group:). Carbon number 2, 4, alkyl group: isodecyl, number of ester bonds: 2, cation: K ⁺ ) 8.0 parts, propylene glycol 2.0 parts, dialkyl succinate sulfonate Na 2.5 parts, polyacrylate Na 2. 0 part, dextrin 6.0 part, pearlite 23.0 part, clay 16.5 part (of which the composition used for the slurry is ipphencarbazone 10.0 part, dialkylsuccinate sulfonate Na 1.0 part, water 14 part. .0 part), the particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 124. The particle size of the obtained pharmaceutical product was 96% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 116.

[Example 137]
The composition of the preparation was 10.0 parts of ipphencarbazone (herbicidal active ingredient), ceramic balloon (average particle size 20 to 150 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group:). Carbon number 2, alkyl group: 2-ethylhexyl, number of ester bonds: 2, cation: Na ⁺ ) 10.0 parts, propylene glycol 2.0 parts, alkylnaphthalene sulfonic acid Na 2.5 parts, alkylnaphthalene sulfonic acid formaldehyde condensation Product Na 3.0 parts, acrylic acid-vinyl sulfonic acid copolymer Na 2.0 parts, methyl cellulose 3.0 parts, pearlite 25.0 parts, bentonite 17.5 parts (of which the composition used for the slurry is ipphencarbazone 10.0 parts, Na alkylnaphthalene sulfonate 1.0 parts, 14.0 parts of water), the particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 124. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.1, and the number of grains per 1 g was 108.

[Example 138]
The composition of the preparation was 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group:). Carbon number 2, 3, alkyl group: n-octyl, number of ester bonds: 1, cation: H ⁺ ) 6.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: carbon number 2, 4, alkyl Group: 2-ethylhexyl, number of ester bonds: 1, cation: Na ⁺ ) 6.0 parts, propylene glycol 2.5 parts, alkylnaphthalene sulfonic acid Na 2.5 parts, naphthalene sulfonic acid formaldehyde condensate Na 3.0 parts, Acrylic acid-methacrylic acid copolymer Na 2.5 parts, dextrin 6.0 parts, diatomaceous soil 25.0 parts, clay 11.5 parts (of which the composition used for the slurry is ipphencarbazone 10.0 parts, alkylnaphthalene 1.0 part of Na sulfonate, 14.0 parts of water) and a particle size of 3.0 mm were used, and a water-floating pesticide preparation was prepared according to Example 124. The particle size of the obtained pharmaceutical product was 95% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 156.

[Example 139]
The composition of the preparation was 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 70 to 90 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group:). Carbon number 2, 4, alkyl group: 2-ethylhexyl, number of ester bonds: 1, cation: Na ⁺ ) 5.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: carbon number 2, alkyl group: 2-Ethylhexyl, number of ester bonds: 2, cation: Na ⁺ ) 5.0 parts, propylene glycol 2.5 parts, alkylnaphthalene sulfonic acid Na 2.5 parts, acrylic acid-vinyl sulfonic acid copolymer Na 2.0 parts , Polyvinyl alcohol 3.0 parts, white carbon 25.0 parts, bentonite 20.0 parts (of which the composition used for the slurry is ipphencarbazone 10.0 parts, alkylnaphthalene sulfonate Na 1.0 parts, water 14. 0 part), the particle size was 2.8 mm, and a water-floating pesticide preparation was prepared according to Example 124. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.5, and the number of grains per 1 g was 178.

[Example 140]
The composition of the preparation was 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group:). Carbon number 2, 4, alkyl group: n-decyl, number of ester bonds: 1, cation: Na ⁺ ) 7.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: carbon number 2, 4, alkyl Group: n-decyl, number of ester bonds: 2, cation: Na ⁺ ) 3.0 parts, propylene glycol 2.5 parts, dialkyl succinate sulfonate Na 2.5 parts, lignin sulfonate Na 3.0 parts, acrylic acid -Maleic acid copolymer Na 1.5 parts, carboxymethyl cellulose Na 2.0 parts, diatomaceous earth 25.0 parts, bentonite 18.5 parts (of which the composition used for the slurry is ipphencarbazone 10.0 parts, dialkylsuccinate 1.0 part of Na sulfonate, 14.0 parts of water) and a particle size of 3.0 mm were used, and a water-floating pesticide preparation was prepared according to Example 124. The particle size of the obtained pharmaceutical product was 95% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 125.

[Example 141]
The composition of the preparation was 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 90 to 120 μm) (suspended carrier) 25.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: Carbon number 2, 4, alkyl group: 2-ethylhexyl, number of ester bonds: 1, cation: Na ⁺ ) 10.0 parts, dialkyl succinate sulfonic acid Na 2.5 parts, alkylnaphthalene sulfonic acid formaldehyde condensate Na 3.0 , 1.5 parts of acrylic acid-maleic acid copolymer Na, 3.0 parts of carboxymethyl cellulose Na, 22.0 parts of diatomaceous soil, 23.0 parts of bentonite (of which the composition used for the slurry is 10.0 parts of ipphencarbazone). , Na 1.0 part of dialkylsuccinate sulfonic acid, 14.0 parts of water), and the particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 124. The particle size of the obtained pharmaceutical product was 95% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 58.

[Example 142]
The pharmaceutical composition consists of 10.0 parts of ipphencarbazone (herbicidal active ingredient), silas balloon (average particle size 90-120 μm) (suspended carrier) 25.0 parts, propylene glycol 2.5 parts, Na2 dialkylsuccinate sulfonate. .5 parts, alkylnaphthalene sulfonic acid formaldehyde condensate Na 3.0 parts, acrylic acid-vinyl sulfonic acid copolymer Na 2.0 parts, carboxymethyl cellulose Na 3.0 parts, diatomaceous soil 35.0 parts, bentonite 17.0 parts (of which) The composition used for the slurry was 10.0 parts of ipphencarbazone, 1.0 part of Na dialkylsuccinate sulfonic acid, 14.0 parts of water), a particle size of 3.0 mm, and the floating on the water surface according to Example 124. A sex pesticide preparation was prepared. The particle size of the obtained pharmaceutical product was 91% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 112.

[Example 143]
After mixing 10.0 parts of ipfencarbazone (herbicidal active ingredient), 1.0 part of Na dialkylsuccinate sulfonate, and 14.0 parts of water, the average particle size is 1.0 μm with Dynomil (manufactured by Symmulenterprises). Wet pulverization was performed until the slurry was obtained. In addition, 18.0 parts of benfresate (herbicidal active ingredient), polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2 or 3 carbon atoms, alkyl group: n-octyl, number of ester bonds: 1, cation: Na ⁺ ) 12.0 parts, propylene glycol 2.5 parts, dialkyl succinate sulfonate Na 1.5 parts, methyl cellulose 3.0 parts, white carbon 18.0 parts, bentonite 9.0 parts hammer mill (sample mill KIIW-1) , Dalton Co., Ltd.) was pulverized and mixed to obtain a powder mixture. 25.0 parts of the slurry, powder mixture and fly ash balloon (average particle size 80 to 120 μm) (suspended carrier) were mixed with a dual arm kneader (KDHJ, manufactured by Dalton) for 10 minutes, then watered and kneaded for 15 minutes. Next, this hydrolyzed product was granulated by an extrusion granulator equipped with a basket-type screen having a pore size of 3.0 mm. The obtained granulated product was pre-dried, sized with a drum-type granulator, and dried with a fluidized bed dryer. This was sieved at 3.35 mm to 2.00 mm to obtain a water-floating pesticide preparation. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.1, and the number of grains per 1 g was 78.

[Example 144]
Formulation composition: 10.0 parts of ipphencarbazone (herbicidal active ingredient), 18.0 parts of benfresate (herbivorous active ingredient), silas balloon (average particle size 70-90 μm) (floating carrier) 28.0 parts, polyoxy Alkylene alkyl ether phosphate ester salt (alkylene group: 2, 3, 4, alkyl group: n-octyl, number of ester bonds: 2, cation: Na ⁺ ) 6.0 parts, hexylene glycol 2.0 parts , Alkylnaphthalene sulfonate Na 2.5 parts, Polyacrylate Na 2.0 parts, Dextrin 6.0 parts, Calcium silicate 15.0 parts, Bentnite 10.5 parts (Of which, the composition used for the slurry is ipphencarbazone. 10.0 parts, Na alkylnaphthalene sulfonate 1.0 parts, 14.0 parts of water), the particle size was 2.8 mm, and a water-floating pesticide preparation was prepared according to Example 143. The particle size of the obtained pharmaceutical product was 87% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 89.

[Example 145]
Formulation composition: 10.0 parts of ipphencarbazone (herbicidal active ingredient), 18.0 parts of benfresate (herbivorous active ingredient), ceramic balloon (average particle size 20-150 μm) (floating carrier) 28.0 parts, polyoxy Alkylene alkyl ether phosphate ester salt (alkylene group: 2 and 4 carbon atoms, alkyl group: 2-ethylhexyl, number of ester bonds: 1, cation: K ⁺ ) 6.0 parts, propylene glycol 3.0 parts, alkylnaphthalene Na sulfonate 2.5 parts, acrylic acid-vinyl sulfonic acid copolymer Na 1.5 parts, dextrin 6.0 parts, calcium silicate 18.0 parts, clay 7.0 parts (of which the composition used for the slurry is ip Fencarbazone 10.0 parts, alkylnaphthalene sulfonic acid Na 1.0 parts, water 14.0 parts) and a particle size of 2.8 mm were used, and a water-floating pesticide preparation was prepared according to Example 143. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.5, and the number of grains per 1 g was 96.

[Example 146]
Formulation composition: 10.0 parts of ipphencarbazone (herbicidal active ingredient), 18.0 parts of benfresate (herbivorous active ingredient), fly ash balloon (average particle size 80-120 μm) (floating carrier) 25.0 parts, poly Oxyalkylene alkyl ether phosphate ester salt (alkylene group: 2 carbon atoms, alkyl group: 2-ethylhexyl, number of ester bonds: 2, cation: K ⁺ ) 10.0 parts, propylene glycol 2.0 parts, dialkyl succinate Na sulfonate 2.5 parts, methyl cellulose 3.0 parts, white carbon 18.0 parts, bentonite 11.5 parts (of which the composition used for the slurry is ipphencarbazone 10.0 parts, dialkylsuccinate sodium sulfonate 1. 0 part, 14.0 parts of water), the particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 143. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 105.

[Example 147]
Formulation composition: 10.0 parts of ipphencarbazone (herbicidal active ingredient), 18.0 parts of benfresate (herbivorous active ingredient), ceramic balloon (average particle size 20-150 μm) (floating carrier) 28.0 parts, polyoxy Alkylene alkyl ether phosphate ester salt (alkylene group: 2, 3, 4, alkyl group: n-decyl, number of ester bonds: 1, cation: Na ⁺ ) 10.0 parts, propylene glycol 2.0 parts, Dialkyl succinate sulfonic acid Na 2.5 parts, acrylic acid-vinyl sulfonic acid copolymer Na 1.0 parts, methyl cellulose 3.0 parts, white carbon 18.0 parts, bentonite 7.5 parts (of which the composition used for the slurry is , Ipphencarbazone 10.0 parts, dialkylsuccinate sulfonate Na 1.0 parts, water 14.0 parts), and the particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 143. .. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 118.

[Example 148]
Formulation composition: 10.0 parts of ipphencarbazone (herbicidal active ingredient), 18.0 parts of benfresate (herbivorous active ingredient), silas balloon (average particle size 70-90 μm) (floating carrier) 25.0 parts, polyoxy Alkylene alkyl ether phosphate ester salt (alkylene group: 2, 3, 4, alkyl group: n-decyl, number of ester bonds: 2, cation: Na ⁺ ) 12.0 parts, propylene glycol 2.5 parts, Alkylnaphthalene sulfonic acid Na 2.5 parts, methyl cellulose 3.0 parts, calcium silicate 20.0 parts, clay 7.0 parts (of which the composition used for the slurry is ipphencarbazone 10.0 parts, alkylnaphthalene sulfonic acid Na 1.0 part, water 14.0 part), the particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 143. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 93.

[Example 149]
Formulation composition: 10.0 parts of ipphencarbazone (herbicidal active ingredient), 18.0 parts of benfresate (herbivorous active ingredient), fly ash balloon (average particle size 80-120 μm) (floating carrier) 25.0 parts, poly Oxyalkylene alkyl ether phosphate ester salt (alkylene group: 2, 3, 4, alkyl group: isodecyl, number of ester bonds: 1, cation: H ⁺ ) 12.0 parts, propylene glycol 3.0 parts, dialkyl 2.5 parts of succinate sulfonic acid Na, 2.0 parts of acrylic acid-maleic acid copolymer, 3.0 parts of methyl cellulose, 18.0 parts of white carbon, 6.5 parts of clay (of which the composition used for the slurry is ip Fencarbazone 10.0 parts, dialkyl succinate sulfonate Na 1.0 parts, water 14.0 parts), and the particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 143. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 82.

[Example 150]
Formulation composition: 10.0 parts of ipphencarbazone (herbicidal active ingredient), 18.0 parts of benfresate (herbivorous active ingredient), acrylonitrile resin balloon (average particle size 20-40 μm) (floating carrier) 2.5 parts, poly Oxyalkylene alkyl ether phosphate ester salt (alkylene group: 2, 3, 4, alkyl group: isodecyl, number of ester bonds: 2, cation: H ⁺ ) 12.0 parts, propylene glycol 2.0 parts, alkyl Naphthalene sulfonic acid Na 2.5 parts, acrylic acid-methacrylic acid copolymer Na 2.0 parts, dextrin 6.0 parts, calcium silicate 20.0 parts, bentonite 25.0 parts (of which the composition used for the slurry is ip Fencarbazone 10.0 parts, alkylnaphthalene sulfonic acid Na 1.0 parts, water 14.0 parts) and a particle size of 2.8 mm were used, and a water-floating pesticide preparation was prepared according to Example 143. The particle size of the obtained pharmaceutical product was 85% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 73.

[Example 151]
Formulation composition: 10.0 parts of ipphencarbazone (herbicidal active ingredient), 18.0 parts of benfresate (herbivorous active ingredient), ceramic balloon (average particle size 20-150 μm) (floating carrier) 25.0 parts, polyoxy Alkylene alkyl ether phosphate ester salt (alkylene group: 2, 4, alkyl group: 2-ethylhexyl, number of ester bonds: 1, cation: K ⁺ ) 10.0 parts, polyoxyalkylene alkyl ether phosphate salt (Alkylene group: 2 carbon atoms, alkyl group: 2-ethylhexyl, number of ester bonds: 2, cation: K ⁺ ) 2.0 parts, propylene glycol 2.0 parts, dialkyl succinate sulfonate Na 2.5 parts, acrylic Acid-vinyl sulfonic acid copolymer Na 1.5 parts, methyl cellulose 3.0 parts, white carbon 18.0 parts, bentonite 8.0 parts (of which the composition used for the slurry is ipphencarbazone 10.0 parts, dialkyl A water-floating pesticide preparation was prepared according to Example 143 with 1.0 part of Na succinate sulfonate, 14.0 parts of water) and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 75.

[Example 152]
Formulation composition: 10.0 parts of ipphencarbazone (herbicidal active ingredient), 18.0 parts of benfresate (herbivorous active ingredient), ceramic balloon (average particle size 20-150 μm) (floating carrier) 25.0 parts, polyoxy Alkylene alkyl ether phosphate ester salt (alkylene group: 2 or 3 carbon atoms, alkyl group: n-octyl, number of ester bonds: 1, cation: Na ⁺ ) 3.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (Alkylene group: 2, 4, alkyl group: 2-ethylhexyl, number of ester bonds: 1, cation: K ⁺ ) 3.0 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: 2 carbon atoms) 3, 4, Alkyl group: Isodecyl, number of ester bonds: 2, cation: H ⁺ ) 3.0 parts, propylene glycol 3.0 parts, alkylnaphthalene sulfonate Na 2.5 parts, acrylic acid-maleic acid co-weight Combined Na 1.0 parts, methyl cellulose 3.0 parts, white carbon 18.0 parts, bentonite 10.5 parts (of which the composition used for the slurry is ipfencarbazone 10.0 parts, alkylnaphthalene sulfonate Na 1.0 parts , 14.0 parts of water), and the particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 143. The particle size of the obtained pharmaceutical product was 82% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.6, and the number of grains per 1 g was 78.

[Example 153]
Formulation composition: 10.0 parts of ipphencarbazone (herbicidal active ingredient), 18.0 parts of benfresate (herbivorous active ingredient), fly ash balloon (average particle size 80-120 μm) (floating carrier) 25.0 parts, poly Oxyalkylene alkyl ether phosphate ester salt (alkylene group: 2, 3, 4, alkyl group: n-octyl, number of ester bonds: 2, cation: Na ⁺ ) 10.0 parts, propylene glycol 1.5 parts , Alkylnaphthalene sulfonate Na 2.5 parts, Polyacrylate Na 2.0 parts, Dextrin 6.0 parts, White carbon 18.0 parts, Clay 7.0 parts (Of which, the composition used for the slurry is ipphencarbazone 10). .0 parts, Na alkylnaphthalene sulfonate 1.0 parts, 14.0 parts of water), the particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 143. The particle size of the obtained pharmaceutical product was 93% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.1, and the number of grains per 1 g was 83.

[Example 154]
Formulation composition: 10.0 parts of ipphencarbazone (herbicidal active ingredient), 18.0 parts of benfresate (herbivorous active ingredient), silas balloon (average particle size 90-120 μm) (floating carrier) 28.0 parts, polyoxy Alkylene alkyl ether phosphate ester salt (alkylene group: 2, 4, alkyl group: 2-ethylhexyl, number of ester bonds: 1, cation: K ⁺ ) 4.0 parts, polyoxyalkylene alkyl ether phosphate salt (Alkylene group: 2, 3, 4, alkyl group: n-decyl, number of ester bonds: 2, cation: Na ⁺ ) 6.0 parts, propylene glycol 1.5 parts, alkylnaphthalene sulfonic acid Na 2.5 , 2.0 parts of acrylic acid-vinyl sulfonic acid copolymer, 3.0 parts of methyl cellulose, 18.0 parts of calcium silicate, 7.0 parts of bentonite (of which the composition used for the slurry is ipphencarbazone 10. 0 part, Na alkylnaphthalene sulfonate 1.0 part, 14.0 part of water), the particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 143. The particle size of the obtained pharmaceutical product was 83% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 86.

[Example 155]
The composition of the preparation is 10.0 parts of ipphencarbazone (herbicidal active ingredient), 18.0 parts of benfresate (herbivorous active ingredient), silas balloon (average particle size 90-120 μm) (floating carrier) 25.0 parts, polyoxy. Alkylene alkyl ether phosphoric acid ester salt (alkylene group: 2 or 3 carbon atoms, alkyl group: n-octyl, number of ester bonds: 1, cation: Na ⁺ ) 5.0 parts, polyoxyalkylene alkyl ether phosphoric acid ester salt (Alkylene group: 2, 3, 4, alkyl group: n-decyl, number of ester bonds: 1, cation: Na ⁺ ) 2.5 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group: carbon Numbers 2, 3, 4, alkyl groups: isodecyl, number of ester bonds: 2, cations: H ⁺ ) 2.5 parts, propylene glycol 2.0 parts, alkylnaphthalene sulfonate Na 2.5 parts, polyacrylate Na 2. 5 parts, methyl cellulose 3.0 parts, calcium silicate 18.0 parts, clay 9.0 parts (of which the composition used for the slurry is ipfencarbazone 10.0 parts, alkylnaphthalene sulfonate Na 1.0 parts, water. 14.0 parts), the particle size was 2.8 mm, and a water-floating pesticide preparation was prepared according to Example 143. The particle size of the obtained pharmaceutical product was 95% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.1, and the number of grains per 1 g was 85.

[Example 156]
Formulation composition: 10.0 parts of ipphencarbazone (herbicidal active ingredient), 18.0 parts of benfresate (herbivorous active ingredient), silas balloon (average particle size 70-90 μm) (floating carrier) 25.0 parts, polyoxy Alkylene alkyl ether phosphate ester salt (alkylene group: 2 and 4 carbon atoms, alkyl group: 2-ethylhexyl, number of ester bonds: 1, cation: K ⁺ ) 10.0 parts, propylene glycol 2.5 parts, alkylnaphthalene Na sulfonate 2.5 parts, Naphthalene sulfonic acid formaldehyde condensate Na 3.0 parts, Acrylic acid-maleic acid copolymer Na 1.5 parts, Methyl cellulose 3.0 parts, White carbon 18.0 parts, Bentnite 6.5 parts ( Of these, the composition used for the slurry was 10.0 parts of ipphencarbazone, 1.0 part of Na alkylnaphthalene sulfonate, 14.0 parts of water), a particle size of 3.0 mm, and floated on the water surface according to Example 143. A sex pesticide preparation was prepared. The particle size of the obtained pharmaceutical product was 86% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 93.

[Example 157]
The composition of the preparation was 10.0 parts of ipphencarbazone (herbicidal active ingredient), 18.0 parts of benfresate (herbivorous active ingredient), silas balloon (average particle size 90-120 μm) (floating carrier) 25.0 parts, polyoxy. Alkylene alkyl ether phosphate ester salt (alkylene group: 2, 3, 4, alkyl group: n-octyl, number of ester bonds: 2, cationic Na ⁺ ) 8.0 parts, propylene glycol 3.0 parts, dialkyl 2. 2.5 parts of succinate sulfonic acid Na, 3.0 parts of alkylnaphthalene sulfonic acid formaldehyde condensate, 1.0 part of acrylic acid-methacrylic acid copolymer Na, 3.0 parts of methyl cellulose, 18.0 parts of white carbon, bentonite 8. 5 parts (of which the composition used for the slurry is 10.0 parts of ipphencarbazone, 1.0 part of Na dialkylsuccinate sulfonate, 14.0 parts of water), the particle size is 3.0 mm, and conforms to Example 143. Then, a water-floating pesticide preparation was prepared. The particle size of the obtained pharmaceutical product was 94% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 120.

[Example 158]
Formulation composition: 10.0 parts of ipphencarbazone (herbicidal active ingredient), 18.0 parts of benfresate (herbivorous active ingredient), fly ash balloon (average particle size 80-120 μm) (floating carrier) 25.0 parts, poly Oxyalkylene alkyl ether phosphate ester salt (alkylene group: 2, 3, 4, alkyl group: n-octyl, number of ester bonds: 2, cationic Na ⁺ ) 5.0 parts, polyoxyalkylene alkyl ether phosphate Ester salt (alkylene group: 2, 4, alkyl group: 2-ethylhexyl, number of ester bonds: 1, cation K ⁺ ) 5.0 parts, propylene glycol 3.0 parts, alkylnaphthalene sulfonate Na 2.5 parts , Acrylic acid-vinyl sulfonic acid copolymer Na 3.0 parts, polyvinyl alcohol 3.0 parts, white carbon 18.0 parts, clay 7.5 parts (of which the composition used for the slurry is ipphencarbazone 10.0 , 1.0 part of Na alkylnaphthalene sulfonate, 14.0 parts of water), and the particle size was 3.0 mm, and a water-floating pesticide preparation was prepared according to Example 143. The particle size of the obtained pharmaceutical product was 84% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 100.

[Example 159]
Formulation composition: 10.0 parts of ipphencarbazone (herbicidal active ingredient), 18.0 parts of benfresate (herbivorous active ingredient), silas balloon (average particle size 90-120 μm) (floating carrier) 25.0 parts, polyoxy Alkylene alkyl ether phosphate ester salt (alkylene group: 2 carbon atoms, alkyl group: 2-ethylhexyl, number of ester bonds: 2, cation K ⁺ ) 4.5 parts, polyoxyalkylene alkyl ether phosphate ester salt (alkylene group) : 2,3,4 carbon atoms, alkyl group: n-decyl, number of ester bonds: 1, cationic Na ⁺ ) 4.5 parts, propylene glycol 2.0 parts, alkylnaphthalene sulfonate Na 2.5 parts, lignin sulfone Na 3.0 parts acid, 2.0 parts Na acrylic acid-methacrylic acid copolymer, 3.0 parts Na carboxymethyl cellulose, 18.0 parts white carbon, 7.5 parts bentnite (of which the composition used for the slurry is ipphencarba). A pesticide preparation floating on the surface of the water was prepared according to Example 143 with 10.0 parts of zone, 1.0 part of Na alkylnaphthalene sulfonate, 14.0 parts of water) and a particle size of 3.0 mm. The particle size of the obtained pharmaceutical product was 97% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.2, and the number of grains per 1 g was 90.

[Example 160]
The composition of the preparation was 10.0 parts of ipphencarbazone (herbicidal active ingredient), 18.0 parts of benfresate (herbivorous active ingredient), silas balloon (average particle size 90-120 μm) (floating carrier) 25.0 parts, polyoxy. Alkylene alkyl ether phosphate ester salt (alkylene group: 2, 3, 4, alkyl group: n-decyl, number of ester bonds: 2, cationic Na ⁺ ) 10.0 parts, alkylnaphthalene sulfonic acid Na 2.5 parts , Naphthalene sulfonic acid formaldehyde condensate Na 3.0 parts, acrylic acid-vinyl sulfonic acid copolymer Na 2.0 parts, carboxymethyl cellulose Na 3.0 parts, white carbon 17.0 parts, bentonite 9.5 parts (of which used for slurry The composition was 10.0 parts of ipphencarbazone, 1.0 part of Na alkylnaphthalene sulfonate, 14.0 parts of water), and the particle size was 3.0 mm. Prepared. The particle size of the obtained pharmaceutical product was 93% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.4, and the number of grains per 1 g was 102.

[Example 161]
The pharmaceutical composition consists of 10.0 parts of ipphencarbazone (herbicidal active ingredient), 18.0 parts of benfresate (herbivorous active ingredient), silas balloon (average particle size 90 to 120 μm) (floating carrier) 25.0 parts, propylene glycol. 3.0 parts, alkylnaphthalene sulfonic acid Na 2.5 parts, naphthalene sulfonic acid formaldehyde condensate Na 3.0 parts, acrylic acid-methacrylic acid copolymer Na 2.0 parts, carboxymethyl cellulose Na 3.0 parts, white carbon 21.5 parts Part, clay 12.0 parts (of which the composition used for the slurry is 10.0 parts of ipphencarbazone, 1.0 part of Na alkylnaphthalene sulfonate, 14.0 parts of water), and the particle size is 3.0 mm. A water-floating pesticide preparation was prepared according to Example 143. The particle size of the obtained pharmaceutical product was 95% in the range of 2.80 to 1.70 mm, the major axis / minor axis ratio on the bottom surface was 1.3, and the number of grains per 1 g was 86.

（３）次いで、処理４８時間後に試験区の散布地点を起点とし、１ｍ間隔で２０ｍＬ採水した採水液、および別途作成した１平方メートル（１ｍ×１ｍ、湛水深２ｃｍ）試験区に上記製剤試料０．２５ｇを均一散布したものの４８時間後の採水液中の有効成分濃度を高速液体クロマトグラフィー（ＨＰＬＣ）あるいはガスクロマトグラフィー（ＧＣ）などにより定量し（分解物が生成した場合には、分解物も定量し、農薬活性成分濃度に換算して合算する）、各地点における拡散率（％）を下記式（２）により算出した。

Next, the usefulness of the water-floating pesticide preparation of the present invention will be shown by a test example.
<Diffusivity test 1 (confirmation of diffusivity under shallow water depth and tailwind conditions)>
The paddy field after transplanting the paddy rice is divided by a corrugated sheet so that the area of one section is 100 square meters (4 m × 25 m, flooded depth 2 cm), and under a tailwind of 2 to 3 m / s, examples and comparative examples are performed from one side of the 4 m side. 25 g of the sample prepared according to the above was processed, and the following three items were investigated.
(1) Maximum visual reach of the product 15 minutes after spraying (2) Presence or absence of sediment at the spraying point 15 minutes after spraying The sediment was evaluated according to the following standard table.

(3) Next, 48 hours after the treatment, starting from the spraying point of the test plot, 20 mL of water was sampled at 1 m intervals, and the above preparation sample was placed in a separately prepared 1 square meter (1 m × 1 m, flooded depth 2 cm) test plot. The concentration of the active ingredient in the water sample 48 hours after uniformly spraying 0.25 g was quantified by high performance liquid chromatography (HPLC) or gas chromatography (GC) (decomposition if a decomposition product was produced). The substances were also quantified, converted to the concentration of the active ingredient of pesticides and added up), and the diffusion rate (%) at each point was calculated by the following formula (2).

The maximum distance at the point where the diffusion rate was 90% or more was defined as the diffusion distance, and the diffusivity was evaluated. In addition, this test was carried out on the product immediately after preparation and the product stored at 40 ° C. for 90 days (corresponding to storage at room temperature for 3 years).

<Diffusivity test 2 (confirmation of diffusivity in shallow water depth and no wind conditions)>
Divide with a corrugated plate so that the area of one section is 120 square meters (4 m x 30 m, flooded depth 2 cm), and under windless conditions, treat 30 g of the sample prepared according to the example from one side of the 4 m side, and treat the following 3 We investigated the items.
(1) Maximum visual reach of the product 15 minutes after spraying (2) Presence or absence of sediment at the spraying point 15 minutes after spraying The sediment was evaluated according to the above standard table.
(3) Next, 24 hours after the treatment, starting from the spraying point of the test plot, 20 mL of water was sampled at 1.5 m intervals, and a separately prepared 1 square meter (1 m x 1 m, flooded depth 2 cm) test plot was used as described above. The concentration of the active ingredient in the water sample 24 hours after uniformly spraying 0.25 g of the preparation sample was quantified by high performance liquid chromatography (HPLC) or gas chromatography (GC) (if a decomposition product was produced). , Decomposed products are also quantified, converted to the concentration of pesticide active ingredient and added up), and the diffusion rate (%) at each point was calculated by the above formula (2).

The maximum distance at the point where the diffusion rate was 90% or more was defined as the diffusion distance, and the diffusivity was evaluated. In addition, this test was carried out on products immediately after preparation and products stored at 40 ° C for 150 days (corresponding to storage at room temperature for 5 years).

As a result of the diffusivity test, it can be evaluated that the smaller the amount of sediment at the spraying point, the longer the reach of the product, and the longer the diffusivity is 90% or more, the better the floating and diffusible. ..
The test results are shown in Tables 2-1 to 2-9 (Examples) and Tables 3-1 to 3-5 (Comparative Examples).

<Explanation of the table>
(1) Diffusivity test 1 (confirmation of diffusivity under shallow water depth and tailwind conditions)
The precipitate was affected by the suspended carrier, Na alkylnaphthalene sulfonate or Na dialkyl succinate sulfonate, particle size, major / minor axis ratio of the bottom surface of the grains, and the number of grains per gram. In Examples 1 to 85, which satisfy all the requirements in Tables 2-1 to 2-5, the sediment, the reachable distance of the preparation, and the diffusion distance were in the range where there was no practical problem. On the other hand, in the comparative example in which any of the components was excluded or replaced with a substitute, the sediment at the time of preparation or after storage at 40 ° C. for 90 days was a practically problematic result.
In each of the examples, the preparation to which any of alkylnaphthalene sulfonic acid formaldehyde condensate Na, naphthalene sulfonic acid formaldehyde condensate Na, or partially desulfonated lignin sulfonate Na was added had the performance after 90 days at 40 ° C. The decrease in (precipitate, formulation reach, diffusion distance) was suppressed. In addition, the preparation containing carboxymethyl cellulose Na as a binder had improved sediment and diffusion distance as compared with Examples using other binders. Overall diffusivity is as follows: silas balloon with an average particle size of 90-120 μm, alkylnaphthalene sulfonate Na or dialkyl succinate sulfonate Na, and alkylnaphthalene sulfonic acid formaldehyde condensate Na, naphthalene sulfonate formaldehyde condensate. Contains either Na or partially desulfonated Na lignin sulfonate, contains carboxymethyl cellulose Na as a binder, and has a particle size of 90% by weight or more in the range of 2.80 mm to 1.70 mm, on the bottom surface of the grain. Examples 16, 17, 33, 34, 50, 51, 67, 68, 84, 85, wherein the major axis / minor axis ratio is 1.1 to 1.4 and the number of grains per 1 g is 50 to 150, are immediately after preparation. Best, including after 90 days at 40 ° C.

Based on the above, in order for the water-floating pesticide preparation to fully exhibit the diffusivity of the sediment, the reach of the preparation, and the diffusion distance not only immediately after preparation but also after long-term storage, the pesticide active ingredient, floating carrier, and alkyl Na naphthalene sulfonate or Na dialkyl succinate sulfonate, 80% by weight or more in the particle size range of 2.80 mm to 1.70 mm, major axis / minor axis ratio of the bottom surface of the grain is 1.1 to 1.4, per 1 g An effective means is that the number of grains is 50 to 150, and further, a silas balloon having a particle size in the range of 2.80 mm to 1.70 mm, 90% by weight or more, and a floating carrier having an average particle size of 90 to 120 μm. Being present, containing either alkylnaphthalene sulfonate formaldehyde condensate Na, naphthalene sulfonate formaldehyde condensate Na, or partially desulfonated lignin sulfonate Na, and containing carboxymethyl cellulose Na as a binder. It is an effective means.

(2) Diffusivity test 2 (confirmation of diffusivity under shallow water depth and no wind conditions)
Examples 86 to 102, 105 to 121, 124 to 140, and 143 to 159 containing a water-soluble alkylene glycol such as a polyoxyalkylene alkyl ether phosphoric acid ester salt and propylene glycol do not contain the component, Examples 16 and 17. , 33, 34, 50, 51, 67, 68, 84, 85, 103, 104, 122, 123, 141, 142, 160, 161 compared to sediment, formulation reach at preparation time and after 150 days at 40 ° C. The result was that the diffusion distance was better and the diffusivity was further improved (Tables 2-1 to 2-9).
Further, in the examples containing the polyoxyalkylene alkyl ether phosphoric acid ester salt and propylene glycol, the particle size is 90% by weight or more in the range of 2.80 mm to 1.70 mm, and the floating carrier has an average particle size of 90 to 120 μm. A preparation using a silas balloon, a preparation to which either alkylnaphthalene sulfonic acid formaldehyde condensate Na, naphthalene sulfonate formaldehyde condensate Na, or lignin sulfonate Na was added, and carboxymethyl cellulose Na or polyvinyl alcohol as a binder were contained. The product had better results in sediment, product reach, and diffusion distance at the time of preparation or storage at 40 ° C. for 150 days. Overall diffusivity is as follows: silas balloon with an average particle size of 90-120 μm, alkylnaphthalene sulfonate Na or dialkyl succinate sulfonate Na, and alkylnaphthalene sulfonic acid formaldehyde condensate Na, naphthalene sulfonate formaldehyde condensate. Contains either Na or Na lignin sulfonate, contains carboxymethyl cellulose Na or polyvinyl alcohol as a binder, has a particle size in the range of 2.80 mm to 1.70 mm, 90% by weight or more, and the major axis of the bottom surface of the grain. Examples 102, 121, 140 and 159 having a minor axis ratio of 1.1 to 1.6 were the best, including immediately after preparation and 150 days after 40 ° C.

Based on the above, in order for the water-floating pesticide preparation to exert the diffusivity of the sediment, the reach of the preparation, and the diffusion distance more effectively not only immediately after preparation but also after long-term storage, the pesticide active ingredient and floating property are required. Carrier, polyoxyalkylene alkyl ether phosphate salt, and Na alkylnaphthalene sulfonate or Na dialkyl succinate sulfonate, 80% by weight or more in the range of 2.80 mm to 1.70 mm particle size, major axis / short diameter of the bottom surface of the grain. An effective means is that the diameter ratio is 1.1 to 1.6 and the number of grains per 1 g is 50 to 200, and further, the particle size is 90% by weight or more in the range of 2.80 mm to 1.70 mm. The floating carrier is a silas balloon having an average particle size of 90 to 120 μm, and contains either alkylnaphthalene sulfonic acid formaldehyde condensate Na, naphthalene sulfonic acid formaldehyde condensate Na, or lignin sulfonate Na. It is a more effective means to contain carboxymethyl cellulose Na or polyvinyl alcohol as a binder.

Claims (12)

A water-floating pesticide preparation containing a) a pesticide active ingredient, b) a hollow body as a floating carrier, and c) one or more selected from alkylnaphthalene sulfonate Na and dialkyl succinate sulfonate Na as an anionic surfactant. Water-floating pesticide preparation with the following characteristics:
d) The major axis / minor axis ratio of the bottom surface of the grain is 1.1 to 1.4,
e) The particle size is in the range of 2.80 mm to 1.70 mm, 80% by weight or more, and f) the number of grains per 1 g is 50 to 150. e) The water-floating pesticide preparation according to claim 1, wherein the particle size is 90% by weight or more in the range of 2.80 mm to 1.70 mm. The water-floating pesticide preparation according to claim 1 or 2, wherein the hollow body as the floating carrier is a shirasu balloon having an average particle diameter of 90 to 120 μm. Further, the claim is characterized by containing at least one selected from alkylnaphthalene sulfonic acid formaldehyde condensate Na, naphthalene sulfonic acid formaldehyde condensate Na, and partially desulfonated lignin sulfonate Na as an anionic surfactant. Item 4. The water-floating pesticide preparation according to any one of Items 1 to 3. The water-floating pesticide preparation according to any one of claims 1 to 4, further comprising carboxymethyl cellulose Na as a binder. a) Agricultural chemical active ingredient, b) Hollow body as a floating carrier, c) Polyoxyalkylene alkyl ether phosphate salt and water-soluble alkylene glycol represented by the following general formula (I), and d) Anionic surfactant. A water-floating pesticide preparation containing at least one selected from Na alkylnaphthalene sulfonate and Na dialkyl succinate sulfonate as activators.

[In the formula, R represents a linear or branched alkyl group having 8 to 10 carbon atoms, A represents an alkylene group having 2 to 4 carbon atoms, n represents an integer of 1 to 20, and p. And q represent integers p + q = 3 and p = 1 or 2, and M represents a hydrogen atom, an alkali metal atom, an ammonium group, or an organic ammonium group. When there are a plurality of R, A, and M, the types may be the same or different. ] The water-floating pesticide preparation according to claim 6, wherein the water-soluble alkylene glycol is propylene glycol. The water-floating pesticide preparation according to claim 6 or 7, which has the following characteristics.
e) The major axis / minor axis ratio of the bottom surface of the grain is 1.1 to 1.6,
f) 80% by weight or more in the range of particle size of 2.80 mm to 1.70 mm, and g) 50 to 200 grains per 1 g. f) The water-floating pesticide preparation according to claim 8, wherein the particle size is 90% by weight or more in the range of 2.80 mm to 1.70 mm. The water-floating pesticide preparation according to any one of claims 6 to 9, wherein the hollow body as the floating carrier is a shirasu balloon having an average particle diameter of 90 to 120 μm. Further, claims 6 to 10 include, as an anionic surfactant, one or more selected from alkylnaphthalene sulfonic acid formaldehyde condensate Na, naphthalene sulfonic acid formaldehyde condensate Na, and lignin sulfonate Na. The water-floating pesticide preparation according to any one of. The water-floating pesticide preparation according to any one of claims 6 to 11, further comprising one or more selected from carboxymethyl cellulose Na and polyvinyl alcohol as a binder.