JPWO2020022512A5 - - Google Patents
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- Publication number
- JPWO2020022512A5 JPWO2020022512A5 JP2020532522A JP2020532522A JPWO2020022512A5 JP WO2020022512 A5 JPWO2020022512 A5 JP WO2020022512A5 JP 2020532522 A JP2020532522 A JP 2020532522A JP 2020532522 A JP2020532522 A JP 2020532522A JP WO2020022512 A5 JPWO2020022512 A5 JP WO2020022512A5
- Authority
- JP
- Japan
- Prior art keywords
- tcr
- gene
- cells
- recombinase
- drug resistance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018140523 | 2018-07-26 | ||
| JP2018140523 | 2018-07-26 | ||
| PCT/JP2019/029537 WO2020022512A1 (ja) | 2018-07-26 | 2019-07-26 | 外来抗原レセプター遺伝子導入細胞の製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2020022512A1 JPWO2020022512A1 (ja) | 2021-08-02 |
| JPWO2020022512A5 true JPWO2020022512A5 (https=) | 2022-08-02 |
| JP7422365B2 JP7422365B2 (ja) | 2024-01-26 |
Family
ID=69180441
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020532522A Active JP7422365B2 (ja) | 2018-07-26 | 2019-07-26 | 外来抗原レセプター遺伝子導入細胞の製造方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20210381008A1 (https=) |
| EP (1) | EP3845638A4 (https=) |
| JP (1) | JP7422365B2 (https=) |
| CN (1) | CN112752838A (https=) |
| AU (1) | AU2019312008B2 (https=) |
| SG (1) | SG11202101789SA (https=) |
| WO (1) | WO2020022512A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB202006903D0 (en) * | 2020-05-11 | 2020-06-24 | Adaptimmune Ltd | Modified iPSCs |
| WO2022059780A1 (ja) * | 2020-09-18 | 2022-03-24 | サイアス株式会社 | ｉＰＳ細胞を介する再生Ｔ細胞の製造方法 |
| CA3193384A1 (en) | 2020-09-24 | 2022-03-31 | Hiroshi Kawamoto | Method for preparing effector cells with desired specificity |
| AU2021392032A1 (en) | 2020-12-03 | 2023-06-22 | Century Therapeutics, Inc. | Genetically engineered cells and uses thereof |
| US11661459B2 (en) | 2020-12-03 | 2023-05-30 | Century Therapeutics, Inc. | Artificial cell death polypeptide for chimeric antigen receptor and uses thereof |
| AR124414A1 (es) | 2020-12-18 | 2023-03-22 | Century Therapeutics Inc | Sistema de receptor de antígeno quimérico con especificidad de receptor adaptable |
| JPWO2022220146A1 (https=) * | 2021-04-16 | 2022-10-20 | ||
| US20250163475A1 (en) * | 2021-12-27 | 2025-05-22 | Gracell Biotechnologies (Shanghai) Co., Ltd. | Systems and methods for cell modification |
| KR20260047608A (ko) * | 2023-08-04 | 2026-04-08 | 갓코호우징 도쿄리카다이가쿠 | 면역 세포의 제조 방법 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1409646B1 (en) | 2000-12-19 | 2012-06-13 | Altor BioScience Corporation | Transgenic animals comprising a humanized immune system |
| JPWO2011096482A1 (ja) | 2010-02-03 | 2013-06-13 | 国立大学法人 東京大学 | 多能性幹細胞を用いた免疫機能再建法 |
| LT3424947T (lt) * | 2011-10-28 | 2021-03-10 | Regeneron Pharmaceuticals, Inc. | Genetiškai modifikuotos t ląstelių receptorių pelės |
| EP2853590B1 (en) | 2012-05-22 | 2018-11-07 | The University of Tokyo | Method for producing antigen-specific t cells |
| AU2014248119B2 (en) | 2013-04-03 | 2019-06-20 | Memorial Sloan-Kettering Cancer Center | Effective generation of tumor-targeted T-cells derived from pluripotent stem cells |
| WO2016010155A1 (ja) | 2014-07-18 | 2016-01-21 | 宏 河本 | 抗原特異的ｔ細胞受容体遺伝子を有する多能性幹細胞の製造方法 |
| EP3170896B1 (en) * | 2014-07-18 | 2020-03-11 | Kawamoto, Hiroshi | Production method for pluripotent stem cells having antigen-specific t cell receptor gene |
| JPWO2016010153A1 (ja) * | 2014-07-18 | 2017-04-27 | 宏 河本 | 免疫細胞療法用ｔ細胞の誘導方法 |
| CN105316362B (zh) | 2015-08-19 | 2020-03-17 | 暨南大学 | 一种Dual-RMCE介导的TCR基因置换系统及其方法 |
| JP6928604B2 (ja) * | 2015-11-04 | 2021-09-01 | フェイト セラピューティクス，インコーポレイテッド | 万能性細胞のゲノム改変 |
| US11377637B2 (en) * | 2016-04-15 | 2022-07-05 | Memorial Sloan Kettering Cancer Center | Transgenic T cell and chimeric antigen receptor T cell compositions and related methods |
| ES2886631T3 (es) | 2016-04-15 | 2021-12-20 | Univ Kyoto | Método para inducir células T positivas para CD8 específicas de antígeno |
-
2019
- 2019-07-26 CN CN201980062820.4A patent/CN112752838A/zh active Pending
- 2019-07-26 AU AU2019312008A patent/AU2019312008B2/en active Active
- 2019-07-26 JP JP2020532522A patent/JP7422365B2/ja active Active
- 2019-07-26 EP EP19842326.1A patent/EP3845638A4/en active Pending
- 2019-07-26 WO PCT/JP2019/029537 patent/WO2020022512A1/ja not_active Ceased
- 2019-07-26 SG SG11202101789SA patent/SG11202101789SA/en unknown
- 2019-07-26 US US17/262,400 patent/US20210381008A1/en active Pending
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