JP7422365B2 - 外来抗原レセプター遺伝子導入細胞の製造方法 - Google Patents

外来抗原レセプター遺伝子導入細胞の製造方法 Download PDF

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JP7422365B2
JP7422365B2 JP2020532522A JP2020532522A JP7422365B2 JP 7422365 B2 JP7422365 B2 JP 7422365B2 JP 2020532522 A JP2020532522 A JP 2020532522A JP 2020532522 A JP2020532522 A JP 2020532522A JP 7422365 B2 JP7422365 B2 JP 7422365B2
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gene
tcr
cells
region
sequence
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JPWO2020022512A5 (https=
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宏 河本
保年 縣
誠治 永野
晃士 寺田
喬子 増田
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Shiga University of Medical Science NUC
Kyoto University NUC
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Kyoto University NUC
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    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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JP2020532522A 2018-07-26 2019-07-26 外来抗原レセプター遺伝子導入細胞の製造方法 Active JP7422365B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2018140523 2018-07-26
JP2018140523 2018-07-26
PCT/JP2019/029537 WO2020022512A1 (ja) 2018-07-26 2019-07-26 外来抗原レセプター遺伝子導入細胞の製造方法

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JPWO2020022512A1 JPWO2020022512A1 (ja) 2021-08-02
JPWO2020022512A5 JPWO2020022512A5 (https=) 2022-08-02
JP7422365B2 true JP7422365B2 (ja) 2024-01-26

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US (1) US20210381008A1 (https=)
EP (1) EP3845638A4 (https=)
JP (1) JP7422365B2 (https=)
CN (1) CN112752838A (https=)
AU (1) AU2019312008B2 (https=)
SG (1) SG11202101789SA (https=)
WO (1) WO2020022512A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202006903D0 (en) * 2020-05-11 2020-06-24 Adaptimmune Ltd Modified iPSCs
WO2022059780A1 (ja) * 2020-09-18 2022-03-24 サイアス株式会社 ｉＰＳ細胞を介する再生Ｔ細胞の製造方法
CA3193384A1 (en) 2020-09-24 2022-03-31 Hiroshi Kawamoto Method for preparing effector cells with desired specificity
AU2021392032A1 (en) 2020-12-03 2023-06-22 Century Therapeutics, Inc. Genetically engineered cells and uses thereof
US11661459B2 (en) 2020-12-03 2023-05-30 Century Therapeutics, Inc. Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
AR124414A1 (es) 2020-12-18 2023-03-22 Century Therapeutics Inc Sistema de receptor de antígeno quimérico con especificidad de receptor adaptable
JPWO2022220146A1 (https=) * 2021-04-16 2022-10-20
US20250163475A1 (en) * 2021-12-27 2025-05-22 Gracell Biotechnologies (Shanghai) Co., Ltd. Systems and methods for cell modification
KR20260047608A (ko) * 2023-08-04 2026-04-08 갓코호우징 도쿄리카다이가쿠 면역 세포의 제조 방법

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005505236A (ja) 2000-12-19 2005-02-24 アルトー バイオサイエンス コーポレイション ヒト化免疫系を含むトランスジェニック動物
JP2014532413A (ja) 2011-10-28 2014-12-08 リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． 遺伝子改変ｔ細胞受容体マウス
CN105316362A (zh) 2015-08-19 2016-02-10 暨南大学 一种Dual-RMCE介导的TCR基因置换系统及其方法
WO2017079673A1 (en) 2015-11-04 2017-05-11 Fate Therapeutics, Inc. Genomic engineering of pluripotent cells
WO2017180989A2 (en) 2016-04-15 2017-10-19 Memorial Sloan Kettering Cancer Center Transgenic t cell and chimeric antigen receptor t cell compositions and related methods

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JPWO2011096482A1 (ja) 2010-02-03 2013-06-13 国立大学法人 東京大学 多能性幹細胞を用いた免疫機能再建法
EP2853590B1 (en) 2012-05-22 2018-11-07 The University of Tokyo Method for producing antigen-specific t cells
AU2014248119B2 (en) 2013-04-03 2019-06-20 Memorial Sloan-Kettering Cancer Center Effective generation of tumor-targeted T-cells derived from pluripotent stem cells
WO2016010155A1 (ja) 2014-07-18 2016-01-21 宏 河本 抗原特異的ｔ細胞受容体遺伝子を有する多能性幹細胞の製造方法
EP3170896B1 (en) * 2014-07-18 2020-03-11 Kawamoto, Hiroshi Production method for pluripotent stem cells having antigen-specific t cell receptor gene
JPWO2016010153A1 (ja) * 2014-07-18 2017-04-27 宏 河本 免疫細胞療法用ｔ細胞の誘導方法
ES2886631T3 (es) 2016-04-15 2021-12-20 Univ Kyoto Método para inducir células T positivas para CD8 específicas de antígeno

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005505236A (ja) 2000-12-19 2005-02-24 アルトー バイオサイエンス コーポレイション ヒト化免疫系を含むトランスジェニック動物
JP2014532413A (ja) 2011-10-28 2014-12-08 リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． 遺伝子改変ｔ細胞受容体マウス
CN105316362A (zh) 2015-08-19 2016-02-10 暨南大学 一种Dual-RMCE介导的TCR基因置换系统及其方法
WO2017079673A1 (en) 2015-11-04 2017-05-11 Fate Therapeutics, Inc. Genomic engineering of pluripotent cells
WO2017180989A2 (en) 2016-04-15 2017-10-19 Memorial Sloan Kettering Cancer Center Transgenic t cell and chimeric antigen receptor t cell compositions and related methods

Also Published As

Publication number Publication date
EP3845638A1 (en) 2021-07-07
EP3845638A4 (en) 2022-05-11
AU2019312008A1 (en) 2021-03-18
WO2020022512A1 (ja) 2020-01-30
US20210381008A1 (en) 2021-12-09
JPWO2020022512A1 (ja) 2021-08-02
CN112752838A (zh) 2021-05-04
SG11202101789SA (en) 2021-03-30
AU2019312008B2 (en) 2026-04-23

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