JPWO2019225755A1 - Deodorant and inactivating agent - Google Patents

Abstract

To provide a deodorant that deodorizes a tense odor and an inactivating agent that inactivates the psychological or psychologically activating action of the tense odor component. The deodorant and inactivating agent contains at least one of a first deodorant component and a second deodorant component. The first deodorant component contains at least one selected from the first group consisting of silver-bearing zeolite, tocopherol, zinc oxide, camsnar extract, rumpuyan extract, and combinations thereof. The second deodorant component consists of laponite, silver-bearing zeolite, zinc oxide, neem leaf extract, iris root extract, perilla leaf extract, hydroxypropyl-β-cyclodextrin, sanna extract, tocopherol, and a combination thereof. Includes at least one selected from the group.

Description

Related application

The present invention is based on the priority claim of Japanese patent application: Japanese Patent Application No. 2018-100599 (filed on May 25, 2018), and all the contents of the application are incorporated in this document by citation. Shall be.

The present disclosure relates to a deodorant that eliminates or reduces discomfort caused by body odor. The present disclosure relates to an inactivating agent that inactivates the physiological / psychologically active (modulating) action of a component secreted by the human body.

Most of the odors caused by the odorous components emitted from the human skin are unpleasant odors and are generally called "body odors". For example, "aging odor" is known as a body odor peculiar to middle-aged and elderly people (see, for example, Patent Document 1). In order to eliminate the unpleasantness caused by the aging odor, the aging odor suppressing fragrance composition described in Patent Document 1 contains a component having an excellent masking effect on the aging odor and / or a component having an excellent harmony effect on the aging odor. It is compounded.

In addition, sulfur compounds are generally considered to be unpleasant odor components. Patent Document 2 describes at least one selected from the group consisting of butyl 2-methylbutanoate, α-terpinene, dipentene, cis-4-heptenal, 1,4-cineole, trimethylhexylaldehyde and (+)-limonene oxide. Disclosed is an agent for suppressing the odor of a polysulfide compound containing.

Japanese Unexamined Patent Publication No. 11-286428 WO2016 / 204212A1

The present inventors have noticed that there is a peculiar odor around a person who is in a tense state (stressed state) in which the heart rate rises due to mental stress. Therefore, the present inventors have studied the cause of the odor, and found that the odor is a body odor caused by a substance secreted or released from a person in a state of tension or mental stress (hereinafter, "tension" in the present disclosure. It was found to be "odor" or "stress odor").

This tense odor is a sulfur-based odor that many people will find unpleasant. In recent years, there has been increasing interest in body odor, and it is expected that demand for deodorants that can eliminate or reduce discomfort caused by tension odor will increase.

The odor suppressant described in Patent Document 2 refers only to offensive odors from other than the human body such as drains and kitchen waste, and the offensive odor emitted from the human body has not been examined, and the odor described in Patent Document 2 has not been studied. It is unclear whether the inhibitor of the above can suppress the tension odor.

The present inventor states that a component secreted and released from a person in a tense or mentally stressed state (for example, a substance causing a tense odor) has at least one of a physiologically active action and a psychologically active action. thinking. Therefore, for an inactive agent that inactivates the physiologically active action and / or the psychologically active action of a component secreted from a person in a tense state or a mentally stressed state (hereinafter, referred to as "tension odor component"). Demand is expected to increase.

According to the first aspect of the present disclosure, a tension odor deodorant containing at least one of a first deodorant component and a second deodorant component is provided. The first deodorant component comprises at least one selected from the first group consisting of silver-bearing zeolite, tocopherol, zinc oxide, camsnar extract, lumpuyan extract, and combinations thereof. The second deodorant component consists of laponite, silver-bearing zeolite, zinc oxide, neem leaf extract, iris root extract, perilla leaf extract, hydroxypropyl-β-cyclodextrin, sanna extract, tocopherol, and a combination thereof. Includes at least one selected from the group.

According to the second aspect of the present disclosure, a tension odor deodorant containing at least one of a first deodorant component and a second deodorant component is provided. The first deodorant component comprises at least one selected from the first group consisting of silver-bearing zeolite, tocopherol, zinc oxide, camsnar extract, lumpuyan extract, and combinations thereof. The second deodorant component is zinc oxide, laponite, silver-bearing zeolite, dibutylhydroxytoluene, sugar cane extract, biwa leaf extract, iris root extract, perilla leaf extract, hydroxypropyl-β-cyclodextrin, sanna extract, green tea extract, And at least one selected from the third group consisting of combinations thereof, and the like.

According to the third aspect of the present disclosure, an inactivating agent containing at least one of a first deodorant component and a second deodorant component is provided. The first inactivating component comprises at least one selected from the first group consisting of silver-bearing zeolite, tocopherol, zinc oxide, camsnar extract, lumpuyan extract, and combinations thereof. The second inactivating component consists of laponite, silver-bearing zeolite, zinc oxide, neem leaf extract, iris root extract, perilla leaf extract, hydroxypropyl-β-cyclodextrin, sanna extract, tocopherol, and a combination thereof. Includes at least one selected from the group of. The inactivating agent inactivates the psychological or psychologically activating effects of the secretory component.

According to the fourth aspect of the present disclosure, an inactivating agent containing at least one of a first deodorant component and a second deodorant component is provided. The first inactivating agent component comprises at least one selected from the first group consisting of silver-bearing zeolite, tocopherol, zinc oxide, camsnar extract, lumpuyan extract, and combinations thereof. The second inactivating agent component is zinc oxide, laponite, silver-bearing zeolite, dibutylhydroxytoluene, sugar cane extract, biwa leaf extract, iris root extract, perilla leaf extract, hydroxypropyl-β-cyclodextrin, sanna extract, green tea. Includes an extract, and at least one selected from a third group consisting of combinations thereof. The inactivating agent inactivates the psychological or psychologically activating effects of the secretory component.

According to the deodorant of the present disclosure, the discomfort caused by the tense odor can be eliminated or reduced.

According to the inactivating agent of the present disclosure, the psychologically or physiologically activating action of the tension odor component can be inactivated or suppressed.

The graph which shows the result in Example 4.

Preferred forms of each of the above viewpoints are described below.

According to the preferred forms of the first and second viewpoints, the tense odor is an odor emitted from the body due to a tense state and / or mental stress.

According to the preferred forms of the first and second viewpoints, the causative agent of the tension odor contains at least one of allyl mercaptan and dimethyl trisulfide.

According to the preferred embodiments of the first and second viewpoints, the causative agent further contains at least one compound selected from the group consisting of methyl mercaptan, dimethyl sulfide, dimethyl disulfide, and combinations thereof.

According to the preferred embodiments of the first and second viewpoints, the causative agent further comprises 1-octen-3-one.

According to the preferred forms of the third and fourth viewpoints, the secretory component is a component secreted from the body due to tension and / or mental stress.

According to the preferred forms of the third and fourth viewpoints, the secretory component comprises at least one of allyl mercaptan and dimethyl trisulfide.

According to the preferred embodiments of the third and fourth viewpoints, the secretory component further contains at least one compound selected from the group consisting of methyl mercaptan, dimethyl sulfide, dimethyl disulfide, and combinations thereof.

According to the preferred forms of the third and fourth viewpoints, the secretory component further comprises 1-octen-3-one.

The deodorant according to the first embodiment of the present disclosure will be described.

The deodorant of the present disclosure is a deodorant suitably applicable to the body odor (tension odor) emitted when a person is in a tense state and / or a mental stress state. The deodorant in the present disclosure refers to a deodorant that removes or alleviates a bad odor by a chemical action and / or a physical action on a causative substance of a odor to be deodorized (hereinafter referred to as "bad odor"). Even if the components listed in the present disclosure remove or alleviate the malodor by means other than chemical action and / or physical action, it does not fall outside the scope of the deodorant of the present disclosure.

The deodorant of the present disclosure contains at least one of a first deodorant component and a second deodorant component.

The first deodorant component can include at least one selected from the first group consisting of silver-bearing zeolite, tocopherol, zinc oxide (powder), camsnar extract, rumpuyan extract, and combinations thereof. The first deodorant component is considered to be particularly useful for deodorizing the malodor caused by allyl mercaptan among the causative substances of tension odor.

In the present disclosure, the silver-supported zeolite includes, for example, those in which at least a part of ion-exchangeable ions in the zeolite is replaced with silver ions. The silver ion content in the silver-supported zeolite can be, for example, 0.1% by mass to 15% by mass.

The second deodorant component is laponite, silver-bearing zeolite, zinc oxide, neem leaf extract, iris root extract, perilla leaf extract, hydroxypropyl-β-cyclodextrin, sanna extract, tocopherol, dibutylhydroxytoluene, sugar cane extract, biwa leaf. It can contain at least one selected from the second group consisting of extracts, green tea extracts, and combinations thereof. The second deodorant component is considered to be particularly useful for deodorizing the malodor caused by dimethyl trisulfide among the substances causing the tension odor.

The second deodorant components are (A) zinc oxide, (B) laponite, silver-bearing zeolite, dibutylhydroxytoluene, sugar cane extract, biwa leaf extract, iris root extract, perilla leaf extract, hydroxypropyl-β-cyclodextrin. , Sanna extract, green tea extract, and at least one selected from the third group consisting of combinations thereof. According to this combination, the deodorizing effect of the tense odor can be further enhanced.

As zinc oxide, a fine powder can be used. The average particle size of zinc oxide can be, for example, 5 μm or less, 3 μm or less, 2 μm or less, 1 μm or less, or 0.5 μm or less.

The main components of the causative substance of the tense odor are allyl mercaptan and dimethyl trisulfide, as will be described later. Both substances have a particularly large effect on the sense of smell. Therefore, if the odors of allyl mercaptan and dimethyl trisulfide are deodorized, the tension odor can be effectively deodorized.

The method of using the deodorant of the present disclosure and the method of deodorizing a tense odor will be described.

The deodorant of the present disclosure can be sprayed into the air before and / or after the place where a tense odor is generated and / or where it may be generated. The deodorant can also be attached or sprayed on fabric products such as clothes, curtains, carpets, etc. before and / or afterwards. If the deodorant does not adversely affect the skin, the deodorant can be applied to the skin before and / or afterwards. For example, a deodorant can be applied to a portion that is thought to secrete a tense odor component, for example, the palm, armpits, feet, back, head, face, oral cavity, and the like.

The deodorant of the present disclosure can be used in combination with other deodorants, those that remove or alleviate bad odors by chemical, biological, physical actions, etc. For example, the deodorant of the present disclosure may further contain a deodorant component, a deodorant component, another deodorant component, and the like as long as the effect of the deodorant of the present disclosure is not impaired.

According to the deodorant of the present disclosure, it is possible to eliminate or suppress the discomfort that occurs when smelling a tense odor. In addition, a person who is or has been in a tense or mentally stressed state, or a person who may become tense or mentally stressed in the future, can generate a tense odor by using the deodorant of the present disclosure. It is possible to eliminate or reduce the anxiety that may be present and the anxiety that may generate a tense odor before and / or after the fact.

The inactivating agent according to the second embodiment of the present disclosure will be described.

The tension odor component has at least one of a psychologically activating effect and a physiologically activating effect on a person. For example, when a person senses a tension odor, or when an olfactory receptor responds to a tension odor component, it becomes clear that the person is mentally tired, confused, or awake. It's getting better. The tension odor component may have other psychoactive and / or psychologically activating effects. The inactivating agent of the present disclosure has an action of inactivating such a psychoactive action and / or a psychological active action of the tension odor component. That is, when a person senses the scent of the inactivating agent of the present disclosure, when the scent of the inactivating agent and the tension odor are mixed and smelled, when the olfactory receptor responds to the inactivating agent, etc. , The person can eliminate or suppress the psychological and / or psychological modulations described above.

In particular, it was revealed that when a person perceives a tense odor, negative emotions increase. It also became clear that positive emotions tended to decline. Negative emotions include, for example, "anger / hostility", "confusion / embarrassment", "depression / depression", "fatigue / lethargy" and "tension / tension" based on the POMS® (Profile of Mood States) test. "Anxiety" is mentioned. It was found that the tense odor particularly enhances "confusion / embarrassment", "fatigue / lethargy" and "tension / anxiety". In addition, positive emotions include, for example, "vigor / vitality" and "friendship".

The inactivating agent of the present disclosure contains at least one of a first inactivating component and a second inactivating component.

The first inactivating component can include at least one selected from the first group consisting of silver-bearing zeolite, tocopherol, zinc oxide, camsnar extract, lumpuyan extract, and combinations thereof. The first inactivating component is considered to be particularly useful for inactivating the malodor caused by allyl mercaptan among the causative substances of the tension odor.

The second inactivating component is laponite, silver-bearing zeolite, zinc oxide, neem leaf extract, iris root extract, perilla leaf extract, hydroxypropyl-β-cyclodextrin, sanna extract, tocopherol, dibutylhydroxytoluene, sugar cane extract, biwa. It can contain at least one selected from the second group consisting of leaf extract, green tea extract, and combinations thereof. The second inactivating component is considered to be particularly useful for inactivating the malodor caused by dimethyl trisulfide among the substances causing the tension odor.

The second inactivating component is (A) zinc oxide, (B) laponite, silver-bearing zeolite, dibutylhydroxytoluene, sugar cane extract, biwa leaf extract, iris root extract, perilla leaf extract, hydroxypropyl-β-cyclo. It is preferable to include at least one selected from the third group consisting of dextrin, sanna extract, green tea extract, and a combination thereof. According to this combination, the effect of inactivating the tension odor can be further enhanced.

As zinc oxide, a fine powder can be used. The average particle size of zinc oxide can be, for example, 5 μm or less, 3 μm or less, 2 μm or less, 1 μm or less, or 0.5 μm or less.

The psychologically and physiologically activating effects of the tension odor component and the inactivating action of the tension odor component by the inactive agent are described, for example, by a method using a psychological questionnaire, for example, POMS (registered trademark) (Profile of Mood States). ), GACL (General Activity Checklist), etc.

The main components of the causative substance of the tense odor are allyl mercaptan and dimethyl trisulfide, as will be described later. Both substances have a particularly large effect on the sense of smell. Therefore, deodorizing the odors of allyl mercaptan and dimethyl trisulfide can effectively inactivate the psychological and / or physiologically active effects of the tension odor.

The method of using the inactivating agent of the present disclosure and the method of inactivating the tension odor component will be described.

The inactivating agent of the present disclosure can be sprayed into the air before and / or after the place where the tension odor component is generated and / or where it may be generated. The inactivating agent can also be attached or sprayed on fabric products such as garments, curtains, carpets, etc. before and / or afterwards. If the inactivating agent does not adversely affect the skin, the inactivating agent can be applied to the skin before and / or afterwards. For example, the inactivating agent can be applied to a portion that is thought to secrete a tension odor component, for example, the palm, armpits, feet, back, head, face, oral cavity, and the like.

The inactivating agent of the present disclosure can be used in combination with other psychological / physiological action inactivating agents and the like. For example, the inactivating agent of the present disclosure may further contain another inactivating agent as long as the effect of the inactivating agent of the present disclosure is not impaired. Other inactivating agents include, for example, those that remove or alleviate bad odors (for example, tension odors) by chemical, biological, physical actions, etc. (for example, deodorant components, deodorant components, deodorant components). Etc.).

The inactivating agent of the present disclosure can inactivate the psychoactive and / or psychologically activating effects of the tension odor component. Thereby, psychological modulation, physiological modulation and the like caused by the tension odor component can be eliminated or suppressed. Persons who are or have been in a state of tension or psychological stress, or who are at risk of becoming in a state of tension or mental stress, may use the inactivating agents of the present disclosure in advance and / or afterwards. It is possible to take measures such as psychological modulation and physiological modulation.

The method for producing the deodorant and the inactivating agent of the present disclosure is not particularly limited. For example, a deodorant and an inactivating agent can be produced by mixing the deodorant components.

The tense odor and the tense odor component referred to in the present disclosure will be described.

A tense odor is an odor emitted from the body when being tense or under mental stress. Examples of the tension or mental stress referred to here include tension or stress that relies on interpersonal relationships. Interpersonal tension / stress includes, for example, tension / stress during a public presentation (especially in front of a large number of people), tension / stress during an important interview or a pressure interview. And so on. In such a psychological stress state, for example, in the absence of an increase in heart rate due to exercise, the heart rate per minute is 20 bpm (beats per minute) or more, preferably 30 bpm or more higher than that at normal rest. It can also be said that it is in a state of being. Normal rest refers to a state in which the person is at rest without mental stress and has little fluctuation in heart rate, for example, a state in which he / she sits for a predetermined time or longer and relaxes.

The tense odor is believed to be based on the components contained in the blood. In the present disclosure, "generated from the body (secretion / release)" means that it is generated (secreted / released) from the skin, mucous membranes and / or the oral cavity. The "body odor" referred to in the present disclosure also includes halitosis.

The tense odor component contains a compound containing a sulfur element (sulfur compound). Sulfur compounds include at least one of allyl mercaptan and dimethyl trisulfide. Preferably, the tension odor component comprises both allyl mercaptan and dimethyl trisulfide.

Allyl mercaptan can be 0.1 ppb or more, 0.3 ppb or more, 0.5 ppb or more, 1 ppb or more, or 10 ppb or more on a volume basis. Allyl mercaptan can be 1,000 ppm or less, 100 ppm or less, 10 ppm or less, 1 ppm or less, 500 ppb or less, 100 ppb or less, or 10 ppb or less on a volume basis.

Dimethyl trisulfide can be 1 ppb or more, 2 ppb or more, 3 ppb or more, 5 ppb or more, 10 ppb or more, 20 ppb or more, 50 ppb or more, or 100 ppb or more on a volume basis. Dimethyl trisulfide can be 10,000 ppm or less, 1,000 ppm or less, 100 ppm or less, 10 ppm or less, 1 ppm or less, 100 ppb or less, or 10 ppb or less on a volume basis.

In the tension odor component, the mass ratio of allyl mercaptan to dimethyl trisulfide is, for example, 2 parts by mass or more, 5 parts by mass or more, 10 parts by mass or more, or 15 parts by mass with respect to 1 part by mass of allyl mercaptan. Can be more than a part. The mass ratio of allyl mercaptan to dimethyl trisulfide is, for example, 50 parts by mass or less, 40 parts by mass or less, 30 parts by mass or less, or 25 parts by mass or less of dimethyl trisulfide with respect to 1 part by mass of allyl mercaptan. Can be done.

Sulfur compounds other than allyl mercaptan and dimethyl trisulfide (hereinafter referred to as "other sulfur compounds") include hydrogen sulfide, methyl mercaptan, carbon disulfide, dimethyl sulfide, dimethyl disulfide, methyl propyl trisulfide, and these. It may further contain at least one compound selected from the group consisting of combinations of. The total amount of the sulfur compound can be 0.1 ppb or more, 1 ppb or more, or 10 ppb or more on a volume basis. The total amount of the sulfur compound can be 10,000 ppm or less, or 1,000 ppm or less on a volume basis.

The tension odor component can contain 1-octen-3-one as a non-sulfur compound, either additionally or alone with respect to the sulfur compound. 1-octen-3-one can be, on a volume basis, for example, 0.1 ppb or higher, 0.5 ppb or higher, 1 ppb or higher, 10 ppb or higher, 100 ppb or higher, or 1 ppm or higher. 1-octen-3-one can be, for example, 1,000 ppm or less, 100 ppm or less, 10 ppm or less, or 1 ppm or less on a volume basis.

The deodorant and inactivating agent of the present disclosure will be described below with reference to examples. However, the deodorants and inactivating agents of the present disclosure are not limited to the following examples.

[Example 1: Deodorant test for dimethyl trisulfide]
0.05% by mass of the deodorant and 99.95% by mass of dipropylene glycol were mixed to prepare a deodorant solution for each deodorant. 1 mL of the deodorant solution and 5 × 10 ^-4 parts by mass of dimethyl trisulfide with respect to 1 part by mass of the deodorant were injected into a sample tube having a capacity of 30 ml. Three expert panels sniffed the inside of the sample tube and evaluated the deodorizing effect of each deodorant on dimethyl trisulfide according to the following criteria.

[Deodorant effect on substances that cause tension odor]
2 points: The expert panel evaluated that the deodorant had a high deodorizing effect;
1 point: The expert panel evaluated that the deodorant effect of the deodorant was rather high;
0 points: The expert panel evaluated that the deodorant had no deodorizing effect.

Table 1 shows the deodorant tested and the evaluation of the deodorant effect by a specialized panel for each deodorant. The evaluation shown in Table 1 shows the average score of the specialized panel according to the following criteria. The average particle size of zinc oxide used in the following examples is about 0.2 μm.

A: 2 points;
B: 1.5 points or more and less than 2 points;
C: 1 point or more and less than 1.5 points;
D: Less than 1 point.

It was confirmed that the deodorants of Test Examples 1 to 5 had a deodorizing effect on dimethyl trisulfide, which is a causative substance of tension odor. Therefore, the deodorants of Test Examples 1 to 5 are considered to be effective in deodorizing a tense odor.

[Example 2: Deodorant test for allyl mercaptan]
0.10% by mass of deodorant and 99.90% by mass of dipropylene glycol were mixed to prepare a deodorant solution for each deodorant. 1 mL of the deodorant solution and 5 × ^10-6 parts by mass of allyl mercaptan with respect to 1 part by mass of the deodorant were injected into a sample tube having a capacity of 30 ml. Three expert panels sniffed the inside of the sample tube and evaluated the deodorizing effect of each deodorant on allyl mercaptan according to the following criteria. Table 2 shows the deodorant tested and the evaluation of the deodorant effect by a specialized panel for each deodorant. The evaluation criteria are the same as in Example 1.

It was confirmed that the deodorants of Test Examples 10 to 18 had a deodorizing effect on allyl mercaptan, which is a causative substance of a tense odor. Therefore, the deodorants of Test Examples 10 to 18 are considered to be effective in deodorizing a tense odor.

[Example 3: Deodorant test for allyl mercaptan]
0.10% by mass of deodorant and 99.90% by mass of dipropylene glycol were mixed to prepare a deodorant solution for each deodorant. The deodorant contains 50% by mass of zinc oxide as component A and 50% by mass of component B shown in Table 3. 1 mL of the deodorant solution and 2.5 × ^10-6 parts by mass of allyl mercaptan with respect to 1 part by mass of the deodorant were injected into a sample tube having a capacity of 30 ml. Three expert panels sniffed the inside of the sample tube and evaluated the deodorizing effect of each deodorant on allyl mercaptan according to the following criteria. Table 3 shows the tested deodorants and the evaluation of the deodorizing effect by a specialized panel for each deodorant. The evaluation criteria are the same as in Example 1.

When zinc oxide was mixed with another deodorant, the deodorant effect could be generally enhanced as compared with the case where the deodorant component was used alone. For example, comparing Test Examples 10, 16, 22, 23, and 25 shown in Table 2 with Test Examples 26, 32, 37, 38, and 40 shown in Table 3, respectively, the deodorant used in Example 2 is deodorized. By adding zinc oxide to the agent, the deodorizing effect could be enhanced as compared with the deodorant alone. For example, laponite, hydroxypropyl-β-dextrin, sugar cane extract, loquat leaf extract, and green tea extract alone had a low deodorizing effect, but the deodorizing effect could be enhanced by mixing with zinc oxide. That is, it is considered that these deodorant components and zinc oxide have a synergistic effect of deodorization. From this, it is considered that the mixing of a plurality of types of deodorant components is more effective in deodorizing a tense odor. In particular, a deodorant containing zinc oxide as a second deodorant component is considered to be effective in deodorizing a tense odor.

Comparing Test Example 12 and Test Example 28, it was possible to enhance the deodorizing effect by increasing the amount of zinc oxide with respect to the malodor-causing substance. From this, if the amount of the deodorant applied is increased with respect to the tense odor, the deodorizing effect can be further enhanced.

[Example 4: Deodorant test for tension odor model composition]
A deodorant shown in Table 4 was prepared, which contained zinc oxide as component A and hydroxypropyl-β-dextrin as component B. Next, a tension odor model composition containing the tension odor component shown in Table 5 was prepared. Next, 100 μL of the tension odor model composition and 10 μL of the deodorant were mixed in a 100 mL airtight glass container. Then, after allowing the closed glass container to stand for 10 minutes, the gas component existing in the upper space of the closed glass container was directly analyzed by mass spectrometry.

As a result, no tension odor component was detected in the upper space of the closed glass container in which the deodorant and the tension odor model composition were mixed. It is considered that the tension odor component is physically and / or chemically removed from the upper space by being adsorbed by a deodorant or the like. From this, it was confirmed that the deodorant of the present disclosure can effectively deodorize the tense odor.

[Example 5: Psychological / psychological action test]
The subject was allowed to smell the model composition of the tension odor, and the psychological and mental changes of the subject due to the tension odor were confirmed using POMS (registered trademark) and GACL. As a result, it was confirmed that the subject experienced arousal, fatigue and confusion when smelling a tense odor.

Next, when the deodorant of the present disclosure was smelled together with the model composition of tension odor, the subjects did not show the above-mentioned psychological and mental changes. From this, it was confirmed that the deodorant of the present disclosure can inactivate the psychological and psychological effects of the tension odor (secretory component).

POMS® 2 Profile of Mood States Second Edition Adult Short The test that analyzed changes in psychological state using a Japanese test sheet is described in detail below. In this psychological analysis, based on the answers to the questions, "anger / hostility", "confusion / embarrassment", "depression / depression", "fatigue / lethargy" and "tension / anxiety", which are indicators of negative mood, In addition, it is possible to confirm the psychological state regarding "vigor / vitality" and "friendship", which are indicators of positive mood. The test sheet had five questions for each index, and each subject was asked to score the mood presented in each question according to the following criteria (maximum score of 20 points for each index).

0 points: I didn't feel presented at all;
1 point: I felt a little presented;
2 points: The mood presented was ok;
3 points: I felt quite presented;
4 points: There were many feelings presented.

First, eight subjects were rested for 20 minutes. After that, I was asked to answer the question on the above inspection form. This inspection is referred to as "inspection 1".

Next, among the tension odor model compositions shown in Table 6, each subject was asked to continue to smell the tension odor for 5 minutes using the model composition having the lowest concentration perceived by each subject. After that, I was asked to answer the same question as in Examination 1. This inspection is referred to as "inspection 2".

The average value and standard deviation of the scores for each index in tests 1 and 2 were calculated. Table 7 shows the results. FIG. 1 shows a graph of the average value and standard deviation of the scores for each index.

Comparing the results of Test 1 and Test 2, it was found that perceiving a tense odor enhances negative emotions, especially tension, confusion and fatigue, as shown in FIG. On the other hand, positive emotions also tended to decline. From this, it was found that the tense odor has a psychological and psychological effect that directs human emotions in an unstable direction.

As demonstrated in Example 4 above, the deodorant of the present disclosure can remove the tension odor component. Therefore, it was found that the deodorant of the present disclosure can inactivate (eliminate, reduce, and / or alleviate) the negative psychological and psychological effects caused by the tense odor. That is, it was found that the deodorant of the present disclosure can be applied as an inactivating agent for the psychological and psychological effects of tension odor.

The deodorant and inactivating agent of the present disclosure have been described based on the above-described embodiments and examples, but the present invention is not limited to the above-described embodiments and examples, and is within the scope of the present invention. Based on the basic technical idea of the invention, various modifications, modifications and improvements may be included for each disclosed element (including the elements described in the claims, specification and drawings). Further, within the scope of the claims of the present invention, various combinations, substitutions or selections of each disclosed element are possible.

Further issues, objectives and forms (including modified forms) of the present invention will also be apparent from all disclosures of the present invention, including the scope of the claims.

The numerical range described in this document should be construed as any numerical value or range contained within the range specifically described in this document, even if otherwise stated.

0002.
Outline of the Invention Problem to be Solved by the Invention [0006]
The present inventors have noticed that there is a peculiar odor around a person who is in a tense state (stressed state) in which the heart rate rises due to mental stress. Therefore, the present inventors have studied the cause of the odor, and found that the odor is a body odor caused by a substance secreted or released from a person in a state of tension or mental stress (hereinafter, "tension" in the present disclosure. It was found to be "odor" or "stress odor").
[0007]
This tense odor is a sulfur-based odor that many people will find unpleasant. In recent years, there has been increasing interest in body odor, and it is expected that demand for deodorants that can eliminate or reduce discomfort caused by tension odor will increase.
[0008]
The odor suppressant described in Patent Document 2 refers only to offensive odors from other than the human body such as drains and kitchen waste, and the offensive odor emitted from the human body has not been examined, and the odor described in Patent Document 2 has not been studied. It is unclear whether the inhibitor of the above can suppress the tension odor.
[0009]
The present inventor states that a component secreted and released from a person in a tense or mentally stressed state (for example, a substance causing a tense odor) has at least one of a physiologically active action and a psychologically active action. thinking. Therefore, for an inactive agent that inactivates the physiologically active action and / or the psychologically active action of a component secreted from a person in a tense state or a mentally stressed state (hereinafter, referred to as "tension odor component"). Demand is expected to increase.
Means for Solving Problems [0010]
According to the first aspect of the present disclosure, a tension odor deodorant containing at least one of a first deodorant component and a second deodorant component is provided. The first deodorant component comprises at least one selected from the first group consisting of silver-supported zeolite, tocopherol, zinc oxide, and combinations thereof. The second deodorant component is laponite, silver-supported zeolite, zinc oxide,

0003
It contains at least one selected from the second group consisting of neem leaf extract, iris root extract, perilla leaf extract, hydroxypropyl-β-cyclodextrin, sanna extract, tocopherol, and combinations thereof.
[0011]
According to the second aspect of the present disclosure, a tension odor deodorant containing at least one of a first deodorant component and a second deodorant component is provided. The first deodorant component comprises at least one selected from the first group consisting of silver-supported zeolite, tocopherol, zinc oxide, and combinations thereof. The second deodorant component is zinc oxide, laponite, silver-bearing zeolite, dibutylhydroxytoluene, sugar cane extract, biwa leaf extract, iris root extract, perilla leaf extract, hydroxypropyl-β-cyclodextrin, sanna extract, green tea extract, And at least one selected from the third group consisting of combinations thereof, and the like.
[0012]
According to the third aspect of the present disclosure, an inactivating agent containing at least one of a first deodorant component and a second deodorant component is provided. The first inactivating component comprises at least one selected from the first group consisting of silver-supported zeolites, tocopherols, zinc oxide, and combinations thereof. The second inactivating component consists of laponite, silver-bearing zeolite, zinc oxide, neem leaf extract, iris root extract, perilla leaf extract, hydroxypropyl-β-cyclodextrin, sanna extract, tocopherol, and a combination thereof. Includes at least one selected from the group of. The inactivating agent inactivates the psychological or psychologically activating effects of the secretory component.
[0013]
According to the fourth aspect of the present disclosure, an inactivating agent containing at least one of a first deodorant component and a second deodorant component is provided. The first inactivating agent component comprises at least one selected from the first group consisting of silver-supported zeolites, tocopherols, zinc oxide, and combinations thereof. The second inactivating agent component is zinc oxide, laponite, silver-bearing zeolite, dibutylhydroxytoluene, sugar cane extract, loquat leaf extract, iris root extract, perilla leaf extract, hydroxypropyl-β-cyclodeki.

0005
It further contains at least one compound selected from the group consisting of sesame.
[0025]
According to the preferred forms of the third and fourth viewpoints, the secretory component further comprises 1-octen-3-one.
[0026]
The deodorant according to the first embodiment of the present disclosure will be described.
[0027]
The deodorant of the present disclosure is a deodorant suitably applicable to the body odor (tension odor) emitted when a person is in a tense state and / or a mental stress state. The deodorant in the present disclosure refers to a deodorant that removes or alleviates a bad odor by a chemical action and / or a physical action on a causative substance of a odor to be deodorized (hereinafter referred to as "bad odor"). Even if the components listed in the present disclosure remove or alleviate the malodor by means other than chemical action and / or physical action, it does not fall outside the scope of the deodorant of the present disclosure.
[0028]
The deodorant of the present disclosure contains at least one of a first deodorant component and a second deodorant component.
[0029]
The first deodorant component can include at least one selected from the first group consisting of silver-bearing zeolite, tocopherol, zinc oxide (powder), and combinations thereof. The first deodorant component is considered to be particularly useful for deodorizing the malodor caused by allyl mercaptan among the causative substances of tension odor.
[0030]
In the present disclosure, the silver-supported zeolite includes, for example, those in which at least a part of ion-exchangeable ions in the zeolite is replaced with silver ions. The silver ion content in the silver-supported zeolite can be, for example, 0.1% by mass to 15% by mass.
[0031]
The second deodorant component is laponite, silver-bearing zeolite, zinc oxide, neem leaf extract, iris root extract, perilla leaf extract, hydroxypropyl-β-cyclodextrin, sanna extract, tocopherol, dibutylhydroxytoluene, sugar cane extract, biwa leaf. It can contain at least one selected from the second group consisting of extracts, green tea extracts, and combinations thereof. The second deodorant component is dimethyl trisulfide, which is one of the causative substances of tension odor.

0007
Anxiety that a person who is or has been in, or who is likely to become tense or mentally stressed, may be developing a tense odor by using the deodorant of the present disclosure. The anxiety that may generate a tense odor can be eliminated or reduced before and / or afterwards.
[0039]
The inactivating agent according to the second embodiment of the present disclosure will be described.
[0040]
The tension odor component has at least one of a psychologically activating effect and a physiologically activating effect on a person. For example, when a person senses a tension odor, or when an olfactory receptor responds to a tension odor component, it becomes clear that the person is mentally tired, confused, or awake. It's getting better. The tension odor component may have other psychoactive and / or psychologically activating effects. The inactivating agent of the present disclosure has an action of inactivating such a psychoactive action and / or a psychological active action of the tension odor component. That is, when a person senses the scent of the inactivating agent of the present disclosure, when the scent of the inactivating agent and the tension odor are mixed and smelled, when the olfactory receptor responds to the inactivating agent, etc. , The person can eliminate or suppress the psychological and / or psychological modulations described above.
[0041]
In particular, it was revealed that when a person perceives a tense odor, negative emotions increase. It also became clear that positive emotions tended to decline. Negative emotions include, for example, "anger / hostility", "confusion / embarrassment", "depression / depression", "fatigue / lethargy" and "tension / tension" based on the POMS® (Profile of Mode States) test. "Anxiety" is mentioned. It was found that the tense odor particularly enhances "confusion / embarrassment", "fatigue / lethargy" and "tension / anxiety". In addition, positive emotions include, for example, "vigor / vitality" and "friendship".
[0042]
The inactivating agent of the present disclosure contains at least one of a first inactivating component and a second inactivating component.
[0043]
The first inactivating component is a first composed of silver-supported zeolite, tocopherol, zinc oxide, and a combination thereof.

0012
0.05% by mass of the deodorant and 99.95% by mass of dipropylene glycol were mixed to prepare a deodorant solution for each deodorant. 1 mL of the deodorant solution and 5 × 10 ^-4 parts by mass of dimethyl trisulfide with respect to 1 part by mass of the deodorant were injected into a sample tube having a capacity of 30 ml. Three expert panels sniffed the inside of the sample tube and evaluated the deodorizing effect of each deodorant on dimethyl trisulfide according to the following criteria.
[0065]
[Deodorant effect on substances that cause tension odor]
2 points: The expert panel evaluated that the deodorant had a high deodorizing effect;
1 point: The expert panel evaluated that the deodorant effect of the deodorant was rather high;
0 points: The expert panel evaluated that the deodorant had no deodorizing effect.
[0066]
Table 1 shows the deodorant tested and the evaluation of the deodorant effect by a specialized panel for each deodorant. The evaluation shown in Table 1 shows the average score of the specialized panel according to the following criteria. The average particle size of zinc oxide used in the following examples is about 0.2 μm.
[0067]
A: 2 points;
B: 1.5 points or more and less than 2 points;
C: 1 point or more and less than 1.5 points;
D: Less than 1 point.
[0068]
It was confirmed that the deodorants of Test Examples 1 to 3 had a deodorizing effect on dimethyl trisulfide, which is a causative substance of tension odor. Therefore, the deodorants of Test Examples 1 to 3 are considered to be effective in deodorizing a tense odor.
[0069]

［００７０］
［実施例２：アリルメルカプタンに対する消臭試験］
消臭剤０．１０質量％とジプロピレングリコール９９．９０質量％とを混合して、それぞれの消臭剤について消臭剤溶液を作製した。消臭剤溶液１ｍＬと、消臭剤１質量部に対して５×１０^−６質量部のアリルメルカプタンと、を３０ミリリットル容量のサンプル管に注入した。専門パネル３人が、サンプル管内の匂いを嗅いで、以下の基準で各消臭剤のアリルメルカプタンに対する消臭効果を評価した。表２に、試験した消臭剤と、各消臭剤についての専門パネルによる消臭効果の評価を示す。評価基準は実施例１と同様である。
［００７１］
試験例８〜１６の消臭剤には、緊張臭の原因物質であるアリルメルカプタンに対する消臭効果が確認された。したがって、試験例８〜１６の消臭剤は、緊張臭の消臭に有効であると考えられる。
［００７２］0013
[Table 1]

[0070]
[Example 2: Deodorant test for allyl mercaptan]
0.10% by mass of deodorant and 99.90% by mass of dipropylene glycol were mixed to prepare a deodorant solution for each deodorant. 1 mL of the deodorant solution and 5 × ^10-6 parts by mass of allyl mercaptan with respect to 1 part by mass of the deodorant were injected into a sample tube having a capacity of 30 ml. Three expert panels sniffed the inside of the sample tube and evaluated the deodorizing effect of each deodorant on allyl mercaptan according to the following criteria. Table 2 shows the deodorant tested and the evaluation of the deodorant effect by a specialized panel for each deodorant. The evaluation criteria are the same as in Example 1.
[0071]
It was confirmed that the deodorants of Test Examples 8 to 16 had a deodorizing effect on allyl mercaptan, which is a causative substance of tension odor. Therefore, the deodorants of Test Examples 8 to 16 are considered to be effective in deodorizing a tense odor.
[0072]

［００７３］
［実施例３：アリルメルカプタンに対する消臭試験］
消臭剤０．１０質量％とジプロピレングリコール９９．９０質量％とを混合して、それぞれの消臭剤について消臭剤溶液を作製した。消臭剤は、成分Ａとして酸化亜鉛５０質量％と、表３に示す成分Ｂ５０質量％と、を含有する。消臭剤溶液１ｍＬと、消臭剤１質量部に対して２．５×１０^−６質量部のアリルメルカプタンと、を３０ミリリットル容量のサンプル管に注入した。専門パネル３人が、サンプル管内の匂いを嗅いで、以下の基準で各消臭剤のアリルメルカプタンに対する消臭効果を評価した。表３に、試験した消臭剤と、各消臭剤についての専門パネルによる消臭効果の評価を示す。評価基準は実施例１と同様である。
［００７４］
酸化亜鉛と他の消臭剤とを混合させると、消臭剤成分を単独で用いるよりも総じて消臭効果を高めることができた。例えば、表２に示す試験例８、１４、２０、２１、及び２３と、表３に示す試験例２４、３０、３５、３６、及び３８とをそれぞれ比較すると、実施例２で使用した消臭剤に酸化亜鉛を添加することによって、消臭剤単独よりも消臭効果を高めることができた。例えば、ラポナイト、ヒドロキシプロピル−β−デキストリン、サトウキビエキス、ビワ葉エキス、及び緑茶エキスは単独では消臭効果が低かったが0014.
[Table 2]

[0073]
[Example 3: Deodorant test for allyl mercaptan]
0.10% by mass of deodorant and 99.90% by mass of dipropylene glycol were mixed to prepare a deodorant solution for each deodorant. The deodorant contains 50% by mass of zinc oxide as component A and 50% by mass of component B shown in Table 3. 1 mL of the deodorant solution and 2.5 × ^10-6 parts by mass of allyl mercaptan with respect to 1 part by mass of the deodorant were injected into a sample tube having a capacity of 30 ml. Three expert panels sniffed the inside of the sample tube and evaluated the deodorizing effect of each deodorant on allyl mercaptan according to the following criteria. Table 3 shows the tested deodorants and the evaluation of the deodorizing effect by a specialized panel for each deodorant. The evaluation criteria are the same as in Example 1.
[0074]
When zinc oxide was mixed with another deodorant, the deodorant effect could be generally enhanced as compared with the case where the deodorant component was used alone. For example, comparing Test Examples 8, 14, 20, 21, and 23 shown in Table 2 with Test Examples 24, 30, 35, 36, and 38 shown in Table 3, respectively, the deodorant used in Example 2 is deodorized. By adding zinc oxide to the agent, the deodorizing effect could be enhanced as compared with the deodorant alone. For example, laponite, hydroxypropyl-β-dextrin, sugar cane extract, loquat leaf extract, and green tea extract alone had a low deodorizing effect.

［００７７］
［実施例４：緊張臭モデル組成物に対する消臭試験］
成分Ａとして酸化亜鉛、成分Ｂとしてヒドロキシプロピル−β−デキストリンを含有する、表４に示す消臭剤を作製した。次に、表５に示す緊張臭成分を含有する緊張臭モデル組成物を作製した。次に、１００ｍＬの密閉ガラス容器中で緊張臭モデル組成物１００μＬ及び消臭剤１０μＬを混合した。そして、密閉ガラス容器を１０分間静置した後、密閉ガラス容器の上部空間に存在する気体成分を直接質量分析法により分析した。
［００７８］
その結果、消臭剤と緊張臭モデル組成物とを混合した密閉ガラス容器の上部空間からは、緊張臭成分が検出されなかった。緊張臭成分は、消臭剤に吸0015.
, The deodorant effect could be enhanced by mixing with zinc oxide. That is, it is considered that these deodorant components and zinc oxide have a synergistic effect of deodorization. From this, it is considered that the mixing of a plurality of types of deodorant components is more effective in deodorizing a tense odor. In particular, a deodorant containing zinc oxide as a second deodorant component is considered to be effective in deodorizing a tense odor.
[0075]
Comparing Test Example 10 and Test Example 26, it was possible to enhance the deodorizing effect by increasing the amount of zinc oxide with respect to the malodor-causing substance. From this, if the amount of the deodorant applied is increased with respect to the tense odor, the deodorizing effect can be further enhanced.
[0076]
[Table 3]

[0077]
[Example 4: Deodorant test for tension odor model composition]
A deodorant shown in Table 4 was prepared, which contained zinc oxide as component A and hydroxypropyl-β-dextrin as component B. Next, a tension odor model composition containing the tension odor component shown in Table 5 was prepared. Next, 100 μL of the tension odor model composition and 10 μL of the deodorant were mixed in a 100 mL airtight glass container. Then, after allowing the closed glass container to stand for 10 minutes, the gas component existing in the upper space of the closed glass container was directly analyzed by mass spectrometry.
[0078]
As a result, no tension odor component was detected in the upper space of the closed glass container in which the deodorant and the tension odor model composition were mixed. Tension odor component is absorbed by deodorant

Claims (12)

Containing at least one of a first deodorant component and a second deodorant component,
The first deodorant component comprises at least one selected from the first group consisting of silver-bearing zeolite, tocopherol, zinc oxide, camsnar extract, lumpuyan extract, and combinations thereof.
The second deodorant component consists of laponite, silver-bearing zeolite, zinc oxide, neem leaf extract, iris root extract, perilla leaf extract, hydroxypropyl-β-cyclodextrin, sanna extract, tocopherol, and a combination thereof. A tension odor deodorant, comprising at least one selected from the group of. Containing at least one of a first deodorant component and a second deodorant component,
The first deodorant component comprises at least one selected from the first group consisting of silver-bearing zeolite, tocopherol, zinc oxide, camsnar extract, lumpuyan extract, and combinations thereof.
The second deodorant component is
With zinc oxide
Select from the third group consisting of laponite, silver-bearing zeolite, dibutylhydroxytoluene, sugar cane extract, biwa leaf extract, iris root extract, perilla leaf extract, hydroxypropyl-β-cyclodextrin, sanna extract, green tea extract, and combinations thereof. A tense odor deodorant, including, with at least one. The tension odor deodorant according to claim 1 or 2, wherein the tension odor is an odor emitted from the body due to a tension state and / or mental stress. The tension odor deodorant according to any one of claims 1 to 3, wherein the causative substance of the tension odor contains at least one of allyl mercaptan and dimethyl trisulfide. The tension odor deodorant according to claim 4, wherein the causative substance further contains at least one compound selected from the group consisting of methyl mercaptan, dimethyl sulfide, dimethyl disulfide, and a combination thereof. The tension odor deodorant according to claim 4 or 5, wherein the causative substance further contains 1-octen-3-one. It contains at least one of the first inactivating component and the second inactivating component.
The first inactivating component comprises at least one selected from the first group consisting of silver-bearing zeolite, tocopherol, zinc oxide, camsnar extract, lumpuyan extract, and combinations thereof.
The second inactivating component consists of laponite, silver-bearing zeolite, zinc oxide, neem leaf extract, iris root extract, perilla leaf extract, hydroxypropyl-β-cyclodextrin, sanna extract, tocopherol, and a combination thereof. Contains at least one selected from the two groups
An inactivating agent that inactivates the psychological or psychoactive effects of secretory components. It contains at least one of the first inactivating component and the second inactivating component.
The first inactivating component is at least one selected from the first group consisting of silver-bearing zeolite, tocopherol, zinc oxide, camsnar extract, lumpuyan extract, and combinations thereof.
The second inactivating component is
With zinc oxide
Select from the third group consisting of laponite, silver-bearing zeolite, dibutylhydroxytoluene, sugar cane extract, biwa leaf extract, iris root extract, perilla leaf extract, hydroxypropyl-β-cyclodextrin, sanna extract, green tea extract, and combinations thereof. Including at least one that is
An inactivating agent that inactivates the psychological or psychoactive effects of secretory components. The inactivating agent according to claim 7 or 8, wherein the secretory component is a component secreted from the body due to tension and / or mental stress. The inactivating agent according to any one of claims 7 to 9, wherein the secretory component contains at least one of allyl mercaptan and dimethyl trisulfide. The inactivation according to any one of claims 7 to 10, wherein the secretory component further contains at least one compound selected from the group consisting of methyl mercaptan, dimethyl sulfide, dimethyl disulfide, and a combination thereof. Agent. The inactivating agent according to any one of claims 7 to 11, wherein the secretory component further comprises 1-octen-3-one.

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