JPWO2019198692A5 - - Google Patents

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Publication number
JPWO2019198692A5
JPWO2019198692A5 JP2020555239A JP2020555239A JPWO2019198692A5 JP WO2019198692 A5 JPWO2019198692 A5 JP WO2019198692A5 JP 2020555239 A JP2020555239 A JP 2020555239A JP 2020555239 A JP2020555239 A JP 2020555239A JP WO2019198692 A5 JPWO2019198692 A5 JP WO2019198692A5
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JP
Japan
Prior art keywords
methyl
oxo
chloro
cyclohexyl
dihydro
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Application number
JP2020555239A
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English (en)
Japanese (ja)
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JP2021521142A (ja
JP7357932B2 (ja
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Priority claimed from PCT/JP2019/015392 external-priority patent/WO2019198692A1/en
Publication of JP2021521142A publication Critical patent/JP2021521142A/ja
Publication of JPWO2019198692A5 publication Critical patent/JPWO2019198692A5/ja
Application granted granted Critical
Publication of JP7357932B2 publication Critical patent/JP7357932B2/ja
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JP2020555239A 2018-04-09 2019-04-09 Ｃｒｈｒ２拮抗薬としての縮合環状尿素誘導体 Active JP7357932B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862654628P 2018-04-09 2018-04-09
US62/654,628 2018-04-09
PCT/JP2019/015392 WO2019198692A1 (en) 2018-04-09 2019-04-09 Fused cyclic urea derivatives as crhr2 antagonist

Publications (3)

Publication Number Publication Date
JP2021521142A JP2021521142A (ja) 2021-08-26
JPWO2019198692A5 true JPWO2019198692A5 (ru) 2023-05-19
JP7357932B2 JP7357932B2 (ja) 2023-10-10

Family

ID=68164246

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020555239A Active JP7357932B2 (ja) 2018-04-09 2019-04-09 Ｃｒｈｒ２拮抗薬としての縮合環状尿素誘導体

Country Status (11)

Country Link
US (1) US11802120B2 (ru)
EP (1) EP3774739B1 (ru)
JP (1) JP7357932B2 (ru)
KR (1) KR102590854B1 (ru)
CN (1) CN111868037B (ru)
BR (1) BR112020020708A8 (ru)
CA (1) CA3094609A1 (ru)
ES (1) ES2917634T3 (ru)
MX (1) MX2020010568A (ru)
TW (1) TWI822754B (ru)
WO (1) WO2019198692A1 (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021145401A1 (en) * 2020-01-15 2021-07-22 Raqualia Pharma Inc. Spiroheterocyclic derivatives as crhr2 antagonist
EP3901152A1 (en) * 2020-04-23 2021-10-27 F. Hoffmann-La Roche AG Kv3 enhancers for the treatment of cognitive disorders
EP4222142A1 (en) * 2020-09-30 2023-08-09 RaQualia Pharma Inc. 3-hydroxyoxindole derivatives as crhr2 antagonist
WO2022228365A1 (zh) * 2021-04-27 2022-11-03 南京明德新药研发有限公司 六元杂芳并脲环的衍生物及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999057103A1 (fr) 1998-04-30 1999-11-11 Nippon Chemiphar Co., Ltd. Derive d'imidazole condense et agent therapeutique permettant de traiter une maladie du foie
BR0209267A (pt) 2001-04-30 2004-06-15 Glaxo Group Ltd Pirimidinas fundidas como antagonistas do fator de liberação de corticotropina (crf)
WO2002100863A1 (en) * 2001-06-12 2002-12-19 Glaxo Group Limited Corticotropin releasing factor antagonists
JP2007161585A (ja) 2004-06-25 2007-06-28 Taisho Pharmaceut Co Ltd 環状アミノ基で置換されているピロロピリミジン及びピロロピリジン誘導体
WO2006044821A1 (en) * 2004-10-19 2006-04-27 Sb Pharmco Puerto Rico Inc. Crf receptor antagonists and methods relating thereto
WO2007149938A2 (en) 2006-06-21 2007-12-27 The Salk Institute Biological Studies Methods for promoting hair growth
US8273900B2 (en) * 2008-08-07 2012-09-25 Novartis Ag Organic compounds
WO2011092293A2 (en) 2010-02-01 2011-08-04 Novartis Ag Cyclohexyl amide derivatives as crf receptor antagonists
JP5748777B2 (ja) * 2010-02-02 2015-07-15 ノバルティス アーゲー Ｃｒｆ受容体アンタゴニストとしてのシクロヘキシルアミド誘導体
WO2013160317A2 (en) * 2012-04-23 2013-10-31 Holsboermaschmeyer Neurochemie Gmbh Crhr1 antagonists for use in the treatment of patients having crh overactivity

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