JPWO2019198692A5 - - Google Patents
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- Publication number
- JPWO2019198692A5 JPWO2019198692A5 JP2020555239A JP2020555239A JPWO2019198692A5 JP WO2019198692 A5 JPWO2019198692 A5 JP WO2019198692A5 JP 2020555239 A JP2020555239 A JP 2020555239A JP 2020555239 A JP2020555239 A JP 2020555239A JP WO2019198692 A5 JPWO2019198692 A5 JP WO2019198692A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- oxo
- chloro
- cyclohexyl
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862654628P | 2018-04-09 | 2018-04-09 | |
| US62/654,628 | 2018-04-09 | ||
| PCT/JP2019/015392 WO2019198692A1 (en) | 2018-04-09 | 2019-04-09 | Fused cyclic urea derivatives as crhr2 antagonist |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021521142A JP2021521142A (ja) | 2021-08-26 |
| JPWO2019198692A5 true JPWO2019198692A5 (pl) | 2023-05-19 |
| JP7357932B2 JP7357932B2 (ja) | 2023-10-10 |
Family
ID=68164246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020555239A Active JP7357932B2 (ja) | 2018-04-09 | 2019-04-09 | Ｃｒｈｒ２拮抗薬としての縮合環状尿素誘導体 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US11802120B2 (pl) |
| EP (1) | EP3774739B1 (pl) |
| JP (1) | JP7357932B2 (pl) |
| KR (1) | KR102590854B1 (pl) |
| CN (1) | CN111868037B (pl) |
| BR (1) | BR112020020708A8 (pl) |
| CA (1) | CA3094609A1 (pl) |
| ES (1) | ES2917634T3 (pl) |
| MX (1) | MX2020010568A (pl) |
| TW (1) | TWI822754B (pl) |
| WO (1) | WO2019198692A1 (pl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202140480A (zh) * | 2020-01-15 | 2021-11-01 | 日商拉夸里亞創藥股份有限公司 | 作為crhr2拮抗劑之螺雜環衍生物 |
| EP3901152A1 (en) * | 2020-04-23 | 2021-10-27 | F. Hoffmann-La Roche AG | Kv3 enhancers for the treatment of cognitive disorders |
| EP4222142A4 (en) * | 2020-09-30 | 2024-10-16 | Raqualia Pharma Inc | 3-HYDROXYOXINDOLE DERIVATIVES USEFUL AS CRHR2 ANTAGONISTS |
| CN117279923A (zh) * | 2021-04-27 | 2023-12-22 | 南京明德新药研发有限公司 | 六元杂芳并脲环的衍生物及其应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3538899A (en) * | 1998-04-30 | 1999-11-23 | Nippon Chemiphar Co. Ltd. | Condensed imidazole derivative and therapeutic agent for liver disease |
| HUP0304054A2 (hu) | 2001-04-30 | 2004-04-28 | Glaxo Group Limited | A kortikotropin-realising faktor (CRF) antagonistáiként alkalmazható kondenzált pirimidinek, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények |
| US7462622B2 (en) | 2001-06-12 | 2008-12-09 | Glaxo Group Limited | Pyrrolo[2, 3-d] pyrimidine derivatives as corticotropin releasing factor antagonists |
| JP2007161585A (ja) | 2004-06-25 | 2007-06-28 | Taisho Pharmaceut Co Ltd | 環状アミノ基で置換されているピロロピリミジン及びピロロピリジン誘導体 |
| WO2006044821A1 (en) * | 2004-10-19 | 2006-04-27 | Sb Pharmco Puerto Rico Inc. | Crf receptor antagonists and methods relating thereto |
| US10166271B2 (en) | 2006-06-21 | 2019-01-01 | The Regents Of The University Of California | Methods for promoting hair growth |
| US8273900B2 (en) * | 2008-08-07 | 2012-09-25 | Novartis Ag | Organic compounds |
| WO2011092293A2 (en) | 2010-02-01 | 2011-08-04 | Novartis Ag | Cyclohexyl amide derivatives as crf receptor antagonists |
| US8835444B2 (en) * | 2010-02-02 | 2014-09-16 | Novartis Ag | Cyclohexyl amide derivatives as CRF receptor antagonists |
| JP2015516979A (ja) * | 2012-04-23 | 2015-06-18 | ホルスボールマッシュマイヤー ニューロケミー ゲーエムベーハーＨｏｌｓｂｏｅｒｍａｓｃｈｍｅｙｅｒ Ｎｅｕｒｏｃｈｅｍｉｅ Ｇｍｂｈ | Ｃｒｈ過剰活性を有する患者の治療に用いるためのｃｒｈｒ１アンタゴニスト |
-
2019
- 2019-04-09 KR KR1020207030243A patent/KR102590854B1/ko active IP Right Grant
- 2019-04-09 WO PCT/JP2019/015392 patent/WO2019198692A1/en active Application Filing
- 2019-04-09 TW TW108112345A patent/TWI822754B/zh active
- 2019-04-09 CA CA3094609A patent/CA3094609A1/en active Pending
- 2019-04-09 EP EP19785626.3A patent/EP3774739B1/en active Active
- 2019-04-09 US US17/046,196 patent/US11802120B2/en active Active
- 2019-04-09 BR BR112020020708A patent/BR112020020708A8/pt unknown
- 2019-04-09 CN CN201980019725.6A patent/CN111868037B/zh active Active
- 2019-04-09 MX MX2020010568A patent/MX2020010568A/es unknown
- 2019-04-09 ES ES19785626T patent/ES2917634T3/es active Active
- 2019-04-09 JP JP2020555239A patent/JP7357932B2/ja active Active
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