JPWO2019195554A5 - - Google Patents
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- JPWO2019195554A5 JPWO2019195554A5 JP2020554078A JP2020554078A JPWO2019195554A5 JP WO2019195554 A5 JPWO2019195554 A5 JP WO2019195554A5 JP 2020554078 A JP2020554078 A JP 2020554078A JP 2020554078 A JP2020554078 A JP 2020554078A JP WO2019195554 A5 JPWO2019195554 A5 JP WO2019195554A5
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- JP
- Japan
- Prior art keywords
- pharmaceutical composition
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- administration
- composition according
- hct
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 208000037212 Neonatal hypoxic and ischemic brain injury Diseases 0.000 claims description 5
- 208000033300 perinatal asphyxia Diseases 0.000 claims description 5
- 206010070511 Hypoxic-ischaemic encephalopathy Diseases 0.000 claims description 4
- 230000000735 allogeneic effect Effects 0.000 claims description 4
- 208000009973 brain hypoxia - ischemia Diseases 0.000 claims description 4
- 210000002536 stromal cell Anatomy 0.000 claims description 4
- 210000003954 umbilical cord Anatomy 0.000 claims description 4
- 208000014644 Brain disease Diseases 0.000 claims description 2
- 208000032274 Encephalopathy Diseases 0.000 claims description 2
- 206010021143 Hypoxia Diseases 0.000 claims description 2
- 206010008129 cerebral palsy Diseases 0.000 claims description 2
- 230000035935 pregnancy Effects 0.000 claims description 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 34
- 230000037396 body weight Effects 0.000 claims 3
- 238000001990 intravenous administration Methods 0.000 claims 3
- 238000007910 systemic administration Methods 0.000 claims 3
- 238000000034 method Methods 0.000 description 18
- 238000000528 statistical test Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862652818P | 2018-04-04 | 2018-04-04 | |
| US62/652,818 | 2018-04-04 | ||
| PCT/US2019/025796 WO2019195554A1 (en) | 2018-04-04 | 2019-04-04 | Methods of treating cerebral palsy and hypoxic-ischemic encephalopathy using human umbilical cord tissue-derived mesenchymal stromal cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021520353A JP2021520353A (ja) | 2021-08-19 |
| JPWO2019195554A5 true JPWO2019195554A5 (https=) | 2022-04-11 |
| JP2021520353A5 JP2021520353A5 (https=) | 2022-04-11 |
Family
ID=68101217
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020554078A Pending JP2021520353A (ja) | 2018-04-04 | 2019-04-04 | ヒト臍帯組織由来の間葉系間質細胞を使用して脳性麻痺および低酸素性虚血性脳症を処置する方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20210361716A1 (https=) |
| EP (1) | EP3773624A4 (https=) |
| JP (1) | JP2021520353A (https=) |
| KR (1) | KR20210021946A (https=) |
| CN (1) | CN112236152A (https=) |
| AU (1) | AU2019247383B2 (https=) |
| BR (1) | BR112020020288A2 (https=) |
| CA (1) | CA3096037A1 (https=) |
| IL (1) | IL277732A (https=) |
| SG (1) | SG11202009800SA (https=) |
| WO (1) | WO2019195554A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024075676A1 (ja) * | 2022-10-03 | 2024-04-11 | キッズウェル・バイオ株式会社 | 脳性まひの予防又は治療剤 |
| WO2025100424A1 (ja) * | 2023-11-10 | 2025-05-15 | 国立大学法人 東京大学 | 急性脳症治療剤及び急性脳症の治療方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1803193A (zh) * | 2005-01-13 | 2006-07-19 | 中山大学 | 骨髓来源的间质干细胞用于制备治疗缺氧缺血性脑性瘫痪的制剂的用途 |
| US20070128722A1 (en) * | 2005-12-05 | 2007-06-07 | Industrial Technology Research Institute | Human mesenchymal stem cells and culturing methods thereof |
| US20170042944A1 (en) * | 2014-04-21 | 2017-02-16 | Anthrogenesis Corporation | Treatment of conditions and complications in infants |
| WO2016019332A1 (en) * | 2014-07-29 | 2016-02-04 | Ingeneron, Inc. | Method and apparatus for recovery of umbilical cord tissue derived regenerative cells and uses thereof |
| WO2017144552A1 (en) * | 2016-02-22 | 2017-08-31 | Centauri Biotech. S.L. | Pharmaceutical or veterinary cell compositions comprising mesenchymal stromal cells (mscs) and dimethyl sulfoxide (dmso) |
| JP7126703B2 (ja) * | 2016-05-24 | 2022-08-29 | 国立大学法人 東京大学 | 臍帯由来細胞を含む脳障害の治療剤 |
| KR101973284B1 (ko) * | 2017-01-16 | 2019-04-29 | 사회복지법인 삼성생명공익재단 | 신생아 ｈｉｅ 치료용 조성물 |
-
2019
- 2019-04-04 JP JP2020554078A patent/JP2021520353A/ja active Pending
- 2019-04-04 AU AU2019247383A patent/AU2019247383B2/en active Active
- 2019-04-04 BR BR112020020288-6A patent/BR112020020288A2/pt unknown
- 2019-04-04 EP EP19782175.4A patent/EP3773624A4/en active Pending
- 2019-04-04 US US17/044,744 patent/US20210361716A1/en not_active Abandoned
- 2019-04-04 WO PCT/US2019/025796 patent/WO2019195554A1/en not_active Ceased
- 2019-04-04 CA CA3096037A patent/CA3096037A1/en active Pending
- 2019-04-04 KR KR1020207031726A patent/KR20210021946A/ko not_active Ceased
- 2019-04-04 SG SG11202009800SA patent/SG11202009800SA/en unknown
- 2019-04-04 CN CN201980032411.XA patent/CN112236152A/zh active Pending
-
2020
- 2020-10-01 IL IL277732A patent/IL277732A/en unknown
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