JPWO2019178296A5 - - Google Patents

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Publication number
JPWO2019178296A5
JPWO2019178296A5 JP2020548709A JP2020548709A JPWO2019178296A5 JP WO2019178296 A5 JPWO2019178296 A5 JP WO2019178296A5 JP 2020548709 A JP2020548709 A JP 2020548709A JP 2020548709 A JP2020548709 A JP 2020548709A JP WO2019178296 A5 JPWO2019178296 A5 JP WO2019178296A5
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JP
Japan
Prior art keywords
cells
cell
reprogramming
aged
aging
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020548709A
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English (en)
Japanese (ja)
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JP2021518331A (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/022149 external-priority patent/WO2019178296A1/fr
Publication of JP2021518331A publication Critical patent/JP2021518331A/ja
Publication of JPWO2019178296A5 publication Critical patent/JPWO2019178296A5/ja
Priority to JP2023172587A priority Critical patent/JP2024016026A/ja
Pending legal-status Critical Current

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JP2020548709A 2018-03-13 2019-03-13 細胞加齢の反転のための一過性細胞リプログラミング Pending JP2021518331A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023172587A JP2024016026A (ja) 2018-03-13 2023-10-04 細胞加齢の反転のための一過性細胞リプログラミング

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862642538P 2018-03-13 2018-03-13
US62/642,538 2018-03-13
PCT/US2019/022149 WO2019178296A1 (fr) 2018-03-13 2019-03-13 Reprogrammation cellulaire transitoire d'inversion du vieillissement cellulaire

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023172587A Division JP2024016026A (ja) 2018-03-13 2023-10-04 細胞加齢の反転のための一過性細胞リプログラミング

Publications (2)

Publication Number Publication Date
JP2021518331A JP2021518331A (ja) 2021-08-02
JPWO2019178296A5 true JPWO2019178296A5 (fr) 2023-03-02

Family

ID=67907311

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020548709A Pending JP2021518331A (ja) 2018-03-13 2019-03-13 細胞加齢の反転のための一過性細胞リプログラミング
JP2023172587A Pending JP2024016026A (ja) 2018-03-13 2023-10-04 細胞加齢の反転のための一過性細胞リプログラミング

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023172587A Pending JP2024016026A (ja) 2018-03-13 2023-10-04 細胞加齢の反転のための一過性細胞リプログラミング

Country Status (13)

Country Link
US (1) US20210010034A1 (fr)
EP (1) EP3764795A4 (fr)
JP (2) JP2021518331A (fr)
KR (1) KR20200131301A (fr)
CN (1) CN112154210A (fr)
AU (1) AU2019235861A1 (fr)
BR (1) BR112020018602A2 (fr)
CA (1) CA3093823A1 (fr)
CR (1) CR20200462A (fr)
IL (1) IL277265A (fr)
MX (1) MX2020009491A (fr)
SG (1) SG11202008839WA (fr)
WO (1) WO2019178296A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
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US20230091910A1 (en) * 2019-04-02 2023-03-23 Centagen, Inc. Engineered System of Stem Cell Rejuvenation to Treat Aging and Disease
US11359011B2 (en) 2019-08-07 2022-06-14 Edifice Health, Inc. Treatment and prevention of cardiovascular disease
TWI789724B (zh) * 2020-03-20 2023-01-11 台灣粒線體應用技術股份有限公司 粒線體用於治療及/或預防肌腱受損或其相關疾病之用途
WO2021211382A1 (fr) * 2020-04-13 2021-10-21 Edifice Health, Inc. Composés et procédés de modification de l'iage
EP4251742A1 (fr) * 2020-11-24 2023-10-04 Lyell Immunopharma, Inc. Procédés de fabrication, compositions comprenant, et procédés d'utilisation de lymphocytes t régénérés
US20230042860A1 (en) 2021-07-15 2023-02-09 Turn Biotechnologies, Inc. Polycistronic expression vectors
CN116334002A (zh) * 2021-10-14 2023-06-27 北京干细胞与再生医学研究院 年轻化骨骼肌肉细胞及其制备方法和应用
WO2023201097A1 (fr) 2022-04-15 2023-10-19 Turn Biotechnologies, Inc. Procédés et compositions pour le rajeunissement et les thérapies de cellules immunitaires à l'aide de cellules immunitaires régénérées
WO2023215857A2 (fr) * 2022-05-06 2023-11-09 President And Fellows Of Harvard College Traitements pour un dysfonctionnement cellulaire lié à l'âge
WO2024012503A1 (fr) * 2022-07-12 2024-01-18 南京瑞初医药有限公司 Composition et sa méthode d'utilisation
WO2024012502A1 (fr) * 2022-07-12 2024-01-18 南京瑞初医药有限公司 Composition et son procédé d'utilisation
CN116426469B (zh) * 2023-06-07 2023-09-08 北京大学口腔医学院 LAP2α在间充质干细胞成脂向分化中的应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9012219B2 (en) * 2005-08-23 2015-04-21 The Trustees Of The University Of Pennsylvania RNA preparations comprising purified modified RNA for reprogramming cells
PL2578685T3 (pl) * 2005-08-23 2020-01-31 The Trustees Of The University Of Pennsylvania Rna zawierający zmodyfikowane nukleozydy i sposoby jego zastosowania
US8669048B2 (en) * 2008-06-24 2014-03-11 Parkinson's Institute Pluripotent cell lines and methods of use thereof
KR102171849B1 (ko) * 2009-12-07 2020-10-30 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 세포 리프로그래밍을 위한 정제된 변형 rna를 포함하는 rna 제제
WO2011091048A1 (fr) * 2010-01-19 2011-07-28 The Board Of Trustees Of The Leland Stanford Junior University Conversion directe de cellules en cellules d'autres lignées
WO2011094738A1 (fr) * 2010-02-01 2011-08-04 The Board Of Trustees Of The Leland Stanford Junior University Efficacité améliorée de génération de cellules souches pluripotentes induites
ES2695550T3 (es) * 2011-04-08 2019-01-09 Inst Nat Sante Rech Med Método para rejuvenecer células
US10155929B2 (en) * 2012-05-13 2018-12-18 Allele Biotechnology & Pharmaceuticals, Inc. Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger RNA
EP3104889B1 (fr) * 2014-02-10 2021-10-13 The Board of Trustees of the Leland Stanford Junior University Activation de l'immunité innée pour améliorer la reprogrammation nucléaire de cellules somatiques avec un arnm
WO2016024101A1 (fr) * 2014-08-13 2016-02-18 Timmons James Archibald Diagnostic médical
EP3242934B1 (fr) * 2015-01-08 2021-08-18 The Board of Trustees of the Leland Stanford Junior University Facteurs et cellules pour l'induction d'os, de moelle osseuse et de cartilage
AU2016206649A1 (en) * 2015-01-14 2017-08-03 Memorial Sloan-Kettering Cancer Center Age-modified cells and methods for making age-modified cells
EP3132809A1 (fr) * 2015-08-21 2017-02-22 Bioskinco GmbH Composition et produits comprenant des cellules sénescentes pour une utilisation dans la régénération tissulaire
CA3087254A1 (fr) * 2018-01-02 2019-07-11 Khloris Biosciences, Inc. Utilisation d'un vaccin a base d'ipsc en tant que traitement prophylactique et therapeutique du cancer
US20220162553A1 (en) * 2019-02-15 2022-05-26 The Board Of Trustees Of The Leland Stanford Junior University Generation of type 1 regulatory t cells through transcription factor targeting
WO2020210202A1 (fr) * 2019-04-11 2020-10-15 The Board Of Trustees Of The Leland Stanford Junior University Lymphocytes t cytotoxiques, spécifiques de formes mutées du récepteur du facteur de croissance épidermique, destinés à être utilisés dans le traitement du cancer
US20230045590A1 (en) * 2019-12-23 2023-02-09 The Board Of Trustees Of The Leland Stanford Junior University Genetically corrected cells for therapeutic use

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