JPWO2019002940A5 - - Google Patents
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- JPWO2019002940A5 JPWO2019002940A5 JP2019571959A JP2019571959A JPWO2019002940A5 JP WO2019002940 A5 JPWO2019002940 A5 JP WO2019002940A5 JP 2019571959 A JP2019571959 A JP 2019571959A JP 2019571959 A JP2019571959 A JP 2019571959A JP WO2019002940 A5 JPWO2019002940 A5 JP WO2019002940A5
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- target volume
- target
- permeability
- therapeutic agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762526548P | 2017-06-29 | 2017-06-29 | |
| US201762526545P | 2017-06-29 | 2017-06-29 | |
| US201762526550P | 2017-06-29 | 2017-06-29 | |
| US62/526,545 | 2017-06-29 | ||
| US15/637,163 US11123575B2 (en) | 2017-06-29 | 2017-06-29 | 3D conformal radiation therapy with reduced tissue stress and improved positional tolerance |
| US62/526,548 | 2017-06-29 | ||
| US62/526,550 | 2017-06-29 | ||
| US15/637,163 | 2017-06-29 | ||
| US201762597073P | 2017-12-11 | 2017-12-11 | |
| US201762597076P | 2017-12-11 | 2017-12-11 | |
| US62/597,073 | 2017-12-11 | ||
| US62/597,076 | 2017-12-11 | ||
| PCT/IB2018/000811 WO2019002940A1 (fr) | 2017-06-29 | 2018-06-29 | Administration et dosage ciblés améliorés par cavitation d'un médicament |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020525167A JP2020525167A (ja) | 2020-08-27 |
| JP2020525167A5 JP2020525167A5 (fr) | 2021-07-26 |
| JPWO2019002940A5 true JPWO2019002940A5 (fr) | 2022-07-26 |
Family
ID=63364094
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019571959A Pending JP2020525167A (ja) | 2017-06-29 | 2018-06-29 | キャビテーション強化型の標的化薬物送達および投与 |
| JP2019571960A Active JP7232204B2 (ja) | 2017-06-29 | 2018-06-29 | マイクロバブル強化超音波処置における超音波周波数およびマイクロバブルサイズの最適化 |
| JP2019571961A Active JP7289061B2 (ja) | 2017-06-29 | 2018-06-29 | シミュレーションベースの薬物処置計画 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019571960A Active JP7232204B2 (ja) | 2017-06-29 | 2018-06-29 | マイクロバブル強化超音波処置における超音波周波数およびマイクロバブルサイズの最適化 |
| JP2019571961A Active JP7289061B2 (ja) | 2017-06-29 | 2018-06-29 | シミュレーションベースの薬物処置計画 |
Country Status (4)
| Country | Link |
|---|---|
| EP (3) | EP3645116B1 (fr) |
| JP (3) | JP2020525167A (fr) |
| CN (3) | CN110831665B (fr) |
| WO (3) | WO2019002940A1 (fr) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11123575B2 (en) | 2017-06-29 | 2021-09-21 | Insightec, Ltd. | 3D conformal radiation therapy with reduced tissue stress and improved positional tolerance |
| CA3120586A1 (fr) | 2018-11-28 | 2020-06-04 | Histosonics, Inc. | Systemes et procedes d'histotrypsie |
| US20220161013A1 (en) * | 2019-04-04 | 2022-05-26 | Northwestern University | Improved delivery of drug therapy to the cns by ultrasound-based opening of the blood-brain barrier |
| US11730452B2 (en) | 2019-04-09 | 2023-08-22 | Insightec Ltd. | Systems and methods for regulating microbubbles in ultrasound procedures |
| JP2022541604A (ja) | 2019-07-25 | 2022-09-26 | インサイテック・リミテッド | 超音波療法の間の動的に変化する媒体のための収差補正 |
| US11813485B2 (en) | 2020-01-28 | 2023-11-14 | The Regents Of The University Of Michigan | Systems and methods for histotripsy immunosensitization |
| US20230100912A1 (en) | 2020-03-05 | 2023-03-30 | Insightec, Ltd. | Differential prediction of aberration corrections for ultrasound therapy |
| EP4363861A2 (fr) | 2021-07-01 | 2024-05-08 | Insightec Ltd. | Surveillance de diagnostic et de traitement basée sur une rupture de la barrière hémato-encéphalique |
| CN113714070B (zh) * | 2021-07-26 | 2022-05-24 | 中北大学 | 混合振膜结构宽频带电容式微机械超声换能器设计方法 |
| WO2023180811A2 (fr) * | 2022-03-22 | 2023-09-28 | Insightec Ltd. | Surveillance de la perméabilité d'un tissu pendant des procédures ultrasonores |
| WO2024047580A1 (fr) * | 2022-08-31 | 2024-03-07 | Insightec Ltd. | Résidence tissulaire forcée de molécules de charge utile par rupture acoustique |
| KR102626932B1 (ko) * | 2023-01-03 | 2024-01-23 | 주식회사 뉴머스 | 환자 맞춤형 헬멧 및 이의 제조 방법 |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6369039B1 (en) * | 1998-06-30 | 2002-04-09 | Scimed Life Sytems, Inc. | High efficiency local drug delivery |
| US6309355B1 (en) * | 1998-12-22 | 2001-10-30 | The Regents Of The University Of Michigan | Method and assembly for performing ultrasound surgery using cavitation |
| US7611462B2 (en) | 2003-05-22 | 2009-11-03 | Insightec-Image Guided Treatment Ltd. | Acoustic beam forming in phased arrays including large numbers of transducer elements |
| CA2575677C (fr) * | 2004-08-18 | 2013-01-22 | Bracco Research Sa | Composition renfermant des microvesicules remplies de gaz, destinee a l'imagerie de contraste |
| TWI271202B (en) * | 2004-11-12 | 2007-01-21 | Ching-Hua Wang | Formula for stimulating biological active substance entering skin or mucous membrane and the application of the same |
| CN100536783C (zh) * | 2005-01-19 | 2009-09-09 | 微星科技股份有限公司 | 颅内压量测方法及系统 |
| JP2006231304A (ja) * | 2005-02-28 | 2006-09-07 | Advance Alpha:Kk | マイクロバブル発生方法およびマイクロバブル発生装置 |
| JP4630127B2 (ja) * | 2005-05-17 | 2011-02-09 | 株式会社日立製作所 | 超音波診断治療装置 |
| US8932239B2 (en) | 2005-06-07 | 2015-01-13 | Koninklijke Philips N.V. | Method and apparatus for ultrasound drug delivery and thermal therapy with phase-convertible fluids |
| US20070016039A1 (en) * | 2005-06-21 | 2007-01-18 | Insightec-Image Guided Treatment Ltd. | Controlled, non-linear focused ultrasound treatment |
| JP4369907B2 (ja) * | 2005-07-01 | 2009-11-25 | 株式会社日立製作所 | 音響化学治療装置 |
| CN100386057C (zh) * | 2005-10-31 | 2008-05-07 | 西安交通大学 | 基于包膜微泡的灌注成像与超声控制释放的系统和方法 |
| US8548562B2 (en) * | 2006-04-04 | 2013-10-01 | John Trachtenberg | System and method of guided treatment within malignant prostate tissue |
| EP2152351B1 (fr) * | 2007-05-07 | 2016-09-21 | Guided Therapy Systems, L.L.C. | Procédés et systèmes de modulation de substances médicamenteuses utilisant l'énergie acoustique |
| EP2240081A1 (fr) * | 2007-12-21 | 2010-10-20 | Koninklijke Philips Electronics N.V. | Systèmes et procédés pour suivre et guider des faisceaux ultrasoniques focalisés haute intensité |
| EP2318086B1 (fr) * | 2008-07-23 | 2016-04-13 | Koninklijke Philips N.V. | Administration de médicament induite par les ultrasons |
| WO2010022239A2 (fr) * | 2008-08-20 | 2010-02-25 | Brigham And Women's Hospital, Inc. | Procédé permettant de modifier la perméabilité et la fonction glomérulaires à l’aide d’ultrasons focalisés |
| WO2010030819A1 (fr) * | 2008-09-10 | 2010-03-18 | The Trustees Of Columbia University In The City Of New York | Systèmes et procédés d'ouverture d'un tissu |
| US20120116221A1 (en) * | 2009-04-09 | 2012-05-10 | The Trustees Of The University Of Pennsylvania | Methods and systems for image-guided treatment of blood vessels |
| AU2010240501A1 (en) * | 2009-04-23 | 2011-10-06 | Yeda Research And Development Co. Ltd. | Nasal flow device controller |
| US20120130146A1 (en) * | 2009-05-25 | 2012-05-24 | Merck Patent Gmbh | Continuous administration of cilengitide in cancer treatments |
| EP2480144B1 (fr) * | 2009-09-21 | 2024-03-06 | The Trustees of Columbia University in the City of New York | Systèmes pour ouvrir une barrière tissulaire |
| KR101200249B1 (ko) * | 2009-10-05 | 2012-11-09 | 한국전기연구원 | 경피 약물 전달 장치 |
| CN101698121B (zh) * | 2009-10-23 | 2011-06-22 | 西安交通大学 | 促进药物透过血脑屏障的适型超声系统 |
| CN103180014B (zh) | 2010-07-29 | 2016-12-28 | 因赛泰克有限公司 | 用于非侵入性的治疗疗法的移动补偿 |
| GB201115419D0 (en) * | 2011-09-07 | 2011-10-19 | Univ Leuven Kath | Non-invasive in-situ radiation dosimetry |
| WO2013050903A1 (fr) * | 2011-10-05 | 2013-04-11 | Koninklijke Philips Electronics N.V. | Dosages biologiques pour une administration induite par ultrasons |
| US20130331738A1 (en) * | 2012-06-11 | 2013-12-12 | Board Of Trustees University Of Arkansas | Compositions and methods for potentiating sonothrombolysis |
| KR101991263B1 (ko) * | 2012-06-27 | 2019-06-21 | 제주대학교 산학협력단 | 초음파의 열 효과를 가시화하는 스마트 조직 팬텀 |
| US8927761B2 (en) * | 2012-06-28 | 2015-01-06 | Photocure Asa | Form of hexyl-5-aminolevulinate hydrochloride and methods of using the same |
| US20150196638A1 (en) * | 2012-07-08 | 2015-07-16 | Sunnybrook Health Sciences Centre | System and method for using ultrasound-stimulated microbubble exposures to induce ceramide accumulation in endothelial and tumor cells |
| GB2505740A (en) * | 2012-09-05 | 2014-03-12 | Surf Technology As | Instrument and method for ultrasound mediated drug delivery |
| CN104884127B (zh) * | 2012-10-12 | 2018-11-02 | 博放医疗有限公司 | 用于使用磁共振引导的聚焦超声的高温处置的多焦点声处理 |
| WO2014118632A1 (fr) * | 2013-01-29 | 2014-08-07 | Insightec, Ltd. | Planification d'un traitement par ultrasons focalisés basés sur la simulation |
| WO2014135987A2 (fr) | 2013-03-06 | 2014-09-12 | Insightec, Ltd. | Optimisation de fréquence dans un traitement par ultrasons |
| CN103417249B (zh) * | 2013-07-15 | 2015-06-03 | 南京航空航天大学 | 一种超声检测与治疗一体化的内窥镜 |
| DK3049117T3 (da) * | 2013-09-27 | 2022-10-31 | Exact Therapeutics As | Ultralydsmedieret afgivelse af lægemidler |
| CN103520831A (zh) * | 2013-10-14 | 2014-01-22 | 南京航空航天大学 | 药液超声治疗循环系统 |
| CN104146730A (zh) * | 2014-08-18 | 2014-11-19 | 中国人民解放军第三军医大学第二附属医院 | 医用诊断超声波激励微泡调控双侧血脑屏障通透性的用途 |
| CN107251028A (zh) * | 2014-12-18 | 2017-10-13 | 弗雷塞尼斯医疗保健控股公司 | 进行计算机模拟临床试验的系统和方法 |
| KR101657285B1 (ko) * | 2015-05-13 | 2016-09-19 | 조선대학교산학협력단 | 초음파 치료 시뮬레이션시스템 |
| US9934570B2 (en) | 2015-10-09 | 2018-04-03 | Insightec, Ltd. | Systems and methods for registering images obtained using various imaging modalities and verifying image registration |
| US10475192B2 (en) | 2016-06-10 | 2019-11-12 | Insightec, Ltd. | Motion tracking during non-invasive therapy |
-
2018
- 2018-06-29 EP EP18765703.6A patent/EP3645116B1/fr active Active
- 2018-06-29 WO PCT/IB2018/000811 patent/WO2019002940A1/fr unknown
- 2018-06-29 CN CN201880043567.3A patent/CN110831665B/zh active Active
- 2018-06-29 JP JP2019571959A patent/JP2020525167A/ja active Pending
- 2018-06-29 EP EP18768933.6A patent/EP3645117B1/fr active Active
- 2018-06-29 JP JP2019571960A patent/JP7232204B2/ja active Active
- 2018-06-29 WO PCT/IB2018/000834 patent/WO2019002943A1/fr unknown
- 2018-06-29 EP EP18759374.4A patent/EP3645118B1/fr active Active
- 2018-06-29 JP JP2019571961A patent/JP7289061B2/ja active Active
- 2018-06-29 WO PCT/IB2018/000841 patent/WO2019002947A1/fr unknown
- 2018-06-29 CN CN201880043399.8A patent/CN111132732B/zh active Active
- 2018-06-29 CN CN201880056389.8A patent/CN111032157B/zh active Active
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