JPWO2014178229A1 - 放射性ガリウム結合部位を有するポリペプチド、及び、その放射性ガリウム錯体 - Google Patents

放射性ガリウム結合部位を有するポリペプチド、及び、その放射性ガリウム錯体 Download PDF

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Publication number
JPWO2014178229A1
JPWO2014178229A1 JP2015514773A JP2015514773A JPWO2014178229A1 JP WO2014178229 A1 JPWO2014178229 A1 JP WO2014178229A1 JP 2015514773 A JP2015514773 A JP 2015514773A JP 2015514773 A JP2015514773 A JP 2015514773A JP WO2014178229 A1 JPWO2014178229 A1 JP WO2014178229A1
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Japan
Prior art keywords
group
polypeptide
formula
peptide
radioactive gallium
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Pending
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JP2015514773A
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English (en)
Japanese (ja)
Inventor
英郎 佐治
英郎 佐治
暢也 稲垣
暢也 稲垣
木村 寛之
寛之 木村
健太郎 豊田
健太郎 豊田
洋和 松田
洋和 松田
博樹 松本
博樹 松本
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nihon Medi Physics Co Ltd
Arkray Inc
Kyoto University
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Nihon Medi Physics Co Ltd
Arkray Inc
Kyoto University
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Application filed by Nihon Medi Physics Co Ltd, Arkray Inc, Kyoto University filed Critical Nihon Medi Physics Co Ltd
Publication of JPWO2014178229A1 publication Critical patent/JPWO2014178229A1/ja
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0478Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/57563Vasoactive intestinal peptide [VIP]; Related peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Vascular Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2015514773A 2013-04-30 2014-03-12 放射性ガリウム結合部位を有するポリペプチド、及び、その放射性ガリウム錯体 Pending JPWO2014178229A1 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2013095840 2013-04-30
JP2013095840 2013-04-30
PCT/JP2014/056553 WO2014178229A1 (ja) 2013-04-30 2014-03-12 放射性ガリウム結合部位を有するポリペプチド、及び、その放射性ガリウム錯体

Publications (1)

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JPWO2014178229A1 true JPWO2014178229A1 (ja) 2017-02-23

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JP2015514773A Pending JPWO2014178229A1 (ja) 2013-04-30 2014-03-12 放射性ガリウム結合部位を有するポリペプチド、及び、その放射性ガリウム錯体

Country Status (3)

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JP (1) JPWO2014178229A1 (zh)
TW (1) TW201440791A (zh)
WO (1) WO2014178229A1 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201504064D0 (en) * 2015-03-10 2015-04-22 Accretion Biotechnology Ltd Method and kits for preparing radionuclide complexes

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010515732A (ja) * 2007-01-11 2010-05-13 イミューノメディクス、インコーポレイテッド タンパク質、ペプチドおよび他の分子の改善されたf−18標識化のための方法および組成物
JP2011507863A (ja) * 2007-12-19 2011-03-10 イミューノメディクス、インコーポレイテッド タンパク質、ペプチド、および他の分子のf−18標識のための改良された方法および組成物
WO2012046845A1 (ja) * 2010-10-08 2012-04-12 国立大学法人京都大学 ペプチド誘導体及びその使用
WO2012108476A1 (ja) * 2011-02-09 2012-08-16 国立大学法人京都大学 放射性標識されたポリペプチドの製造方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010515732A (ja) * 2007-01-11 2010-05-13 イミューノメディクス、インコーポレイテッド タンパク質、ペプチドおよび他の分子の改善されたf−18標識化のための方法および組成物
JP2011507863A (ja) * 2007-12-19 2011-03-10 イミューノメディクス、インコーポレイテッド タンパク質、ペプチド、および他の分子のf−18標識のための改良された方法および組成物
WO2012046845A1 (ja) * 2010-10-08 2012-04-12 国立大学法人京都大学 ペプチド誘導体及びその使用
WO2012108476A1 (ja) * 2011-02-09 2012-08-16 国立大学法人京都大学 放射性標識されたポリペプチドの製造方法

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TW201440791A (zh) 2014-11-01
WO2014178229A1 (ja) 2014-11-06

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