JPS6475481A - Production of d,l-trans epoxysuccinic acid - Google Patents
Production of d,l-trans epoxysuccinic acidInfo
- Publication number
- JPS6475481A JPS6475481A JP23069287A JP23069287A JPS6475481A JP S6475481 A JPS6475481 A JP S6475481A JP 23069287 A JP23069287 A JP 23069287A JP 23069287 A JP23069287 A JP 23069287A JP S6475481 A JPS6475481 A JP S6475481A
- Authority
- JP
- Japan
- Prior art keywords
- trans
- acid
- catalyst
- treated
- aqueous solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Epoxy Compounds (AREA)
Abstract
PURPOSE:To obtain the titled compound useful as an intermediate for drugs by simple operation in high yield, by reacting fumaric acid with hydrogen peroxide in an alkali aqueous solution in the presence of a catalyst and treating the reaction product with a strongly acidic ion exchange resin without isolating the reaction product. CONSTITUTION:Fumaric acid is treated with hydrogen peroxide in an alkali aqueous solution in the presence of a small amount of a catalyst (e.g. disodium tungstate dihydrate). Prepared D,L-trans epoxysuccinic acid alkali salt, without isolation, is treated with a strongly acidic ion exchange resin to give the aimed compound. The amount of the catalyst used is preferably 0.05-1.0 equivalent based on the acid.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP23069287A JPS6475481A (en) | 1987-09-14 | 1987-09-14 | Production of d,l-trans epoxysuccinic acid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP23069287A JPS6475481A (en) | 1987-09-14 | 1987-09-14 | Production of d,l-trans epoxysuccinic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6475481A true JPS6475481A (en) | 1989-03-22 |
Family
ID=16911815
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP23069287A Pending JPS6475481A (en) | 1987-09-14 | 1987-09-14 | Production of d,l-trans epoxysuccinic acid |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6475481A (en) |
-
1987
- 1987-09-14 JP JP23069287A patent/JPS6475481A/en active Pending
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