JPS6463539A - Optically active ethanol derivative and production thereof - Google Patents
Optically active ethanol derivative and production thereofInfo
- Publication number
- JPS6463539A JPS6463539A JP9996188A JP9996188A JPS6463539A JP S6463539 A JPS6463539 A JP S6463539A JP 9996188 A JP9996188 A JP 9996188A JP 9996188 A JP9996188 A JP 9996188A JP S6463539 A JPS6463539 A JP S6463539A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- optically active
- halogen
- liquid crystal
- buffer solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:The optically active ethanol derivative of formula I (A is H, lower alkyl, lower alkoxy or halogen; Z is H or halogen; l is 0 or 1; *represents asymmetric C). EXAMPLE:(+)-4-Benzyloxy-1-phenethyl alcohol. USE:An intermediate for a liquid crystal material, especially a ferroelectric liquid crystal material having excellent stability and quick response and an intermediate for agricultural chemicals and pharmaceuticals, etc. PREPARATION:Ether one of optical active compounds of formula I can be produced by mixing (A) dl-esters of formula II (R' is lower alkyl) with (B) an esterase capable of hydrolyzing either one of the enantiomers of the above esters, e.g., an enzyme (such as lipase) originated from animals, vegetables or microorganisms, and vigorously agitating the mixture in a buffer solution (e.g. phosphate buffer solution) at 10-60 deg.C for 10-70hr to effect asymmetric hydrolysis. The unreacted ester is further hydrolyzed to obtain the other compound of formula I which is the antipod of the above compound.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10951187 | 1987-04-30 | ||
| JP11198487 | 1987-05-07 | ||
| JP62-109511 | 1987-05-07 | ||
| JP62-111984 | 1987-05-07 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6463539A true JPS6463539A (en) | 1989-03-09 |
| JP2689474B2 JP2689474B2 (en) | 1997-12-10 |
Family
ID=26449253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP63099961A Expired - Lifetime JP2689474B2 (en) | 1987-04-30 | 1988-04-21 | Optically active ethanol derivative and method for producing the same |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2689474B2 (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01104026A (en) * | 1987-07-17 | 1989-04-21 | Sumitomo Chem Co Ltd | Optically active alcohols and their production |
| JPH02142746A (en) * | 1988-11-24 | 1990-05-31 | Arakawa Chem Ind Co Ltd | Optically active compound and production thereof |
| JP2006248915A (en) * | 2005-03-08 | 2006-09-21 | Kyoto Univ | Optically active sulfur-cross-linked binuclear ruthenium complex, method for producing the same, method for producing optically active compound using the same catalyst and new optically active compound |
-
1988
- 1988-04-21 JP JP63099961A patent/JP2689474B2/en not_active Expired - Lifetime
Non-Patent Citations (1)
| Title |
|---|
| C R ACAD SC PARIS * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01104026A (en) * | 1987-07-17 | 1989-04-21 | Sumitomo Chem Co Ltd | Optically active alcohols and their production |
| JPH02142746A (en) * | 1988-11-24 | 1990-05-31 | Arakawa Chem Ind Co Ltd | Optically active compound and production thereof |
| JP2006248915A (en) * | 2005-03-08 | 2006-09-21 | Kyoto Univ | Optically active sulfur-cross-linked binuclear ruthenium complex, method for producing the same, method for producing optically active compound using the same catalyst and new optically active compound |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2689474B2 (en) | 1997-12-10 |
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