JPS6459057A - Enzyme immune sensor and enzyme immunoassay using sand sensor - Google Patents
Enzyme immune sensor and enzyme immunoassay using sand sensorInfo
- Publication number
- JPS6459057A JPS6459057A JP62215015A JP21501587A JPS6459057A JP S6459057 A JPS6459057 A JP S6459057A JP 62215015 A JP62215015 A JP 62215015A JP 21501587 A JP21501587 A JP 21501587A JP S6459057 A JPS6459057 A JP S6459057A
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- sensor
- antigen
- enzyme
- hydrophilic film
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Thin Film Transistor (AREA)
Abstract
PURPOSE:To measure the quantity of the antigen or antibody in a sample by detecting the difference between a 1st semiconductor ion sensor immobilized with the antigen or antibody in a hydrophilic film and a 2nd semiconductor ion sensor provided only with the hydrophilic film. CONSTITUTION:The enzyme immune sensor 11 having the hydrophilic film immobilized with the antibody or antigen reacting specifically with the antigen or antibody to be measured is immersed in a sample 12 contg. said antigen or antibody to effect an antigen-antibody reaction. This sensor 11 is then immersed in a soln. 13 contg. the antibody or antigen labeled with enzyme to effect the antigen-antibody reaction. The sensor is then immersed in a soln. 14 contg. the substrate to be decomposed or oxidized by the above-mentioned labeling enzyme. The change in the concn. of the ions in the hydrophilic film 7 of the sensor generated by the enzyme reaction of the substrate is measured by the differential output between the semiconductor ion sensor A formed with an antibody immobilized region 8 and the semiconductor ion sensor B provided with only the hydrophilic film 7. The quantity of the antigen or antibody in the sample is measured in accordance with the measured value thereof.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62215015A JPS6459057A (en) | 1987-08-31 | 1987-08-31 | Enzyme immune sensor and enzyme immunoassay using sand sensor |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62215015A JPS6459057A (en) | 1987-08-31 | 1987-08-31 | Enzyme immune sensor and enzyme immunoassay using sand sensor |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS6459057A true JPS6459057A (en) | 1989-03-06 |
JPH0549186B2 JPH0549186B2 (en) | 1993-07-23 |
Family
ID=16665312
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62215015A Granted JPS6459057A (en) | 1987-08-31 | 1987-08-31 | Enzyme immune sensor and enzyme immunoassay using sand sensor |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6459057A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5328847A (en) * | 1990-02-20 | 1994-07-12 | Case George D | Thin membrane sensor with biochemical switch |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS54161992A (en) * | 1978-06-13 | 1979-12-22 | Asahi Glass Co Ltd | Immunity sensor and making method thereof |
JPS60247151A (en) * | 1984-05-23 | 1985-12-06 | Fujitsu Ltd | Fet biosensor |
-
1987
- 1987-08-31 JP JP62215015A patent/JPS6459057A/en active Granted
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS54161992A (en) * | 1978-06-13 | 1979-12-22 | Asahi Glass Co Ltd | Immunity sensor and making method thereof |
JPS60247151A (en) * | 1984-05-23 | 1985-12-06 | Fujitsu Ltd | Fet biosensor |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5328847A (en) * | 1990-02-20 | 1994-07-12 | Case George D | Thin membrane sensor with biochemical switch |
Also Published As
Publication number | Publication date |
---|---|
JPH0549186B2 (en) | 1993-07-23 |
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Legal Events
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