JPS6456681A - Novel macrolide compound - Google Patents
Novel macrolide compoundInfo
- Publication number
- JPS6456681A JPS6456681A JP21080587A JP21080587A JPS6456681A JP S6456681 A JPS6456681 A JP S6456681A JP 21080587 A JP21080587 A JP 21080587A JP 21080587 A JP21080587 A JP 21080587A JP S6456681 A JPS6456681 A JP S6456681A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- alkyl
- acid residue
- double bond
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
NEW MATERIAL:The compound of formula I [X is H, OH or oxo; the dotted line is single or double bond (double bond exclusively in the case of X is H); R<1> is 4-8C alkyl, 2-8C alkenyl, 1-4C alkoxy, alkylthio-1-4C alkyl, 3-8C aycloalkyl, 3-6-membered heterocyclic group containing O or S, etc.; R<2> is =O or OR<4> (R<4> is H or ester-forming carboxylic acid residue or carbonic acid residue); R<3> is halogen]. EXAMPLE:13-Fluoro LL-F28249alpha. USE:An insecticidal, miticidal and anthelmintic agent. PREPARATION:The objective compound can be produced by selectively oxidizing the 5-hydroxyl group of a milbemycin-analog compound of formula II with active manganese dioxide, oxidizing the 13-position of the obtained 5-ketone compound of formula III to form 13-hydroxy-5-ketone compound of formula IV and reacting the compound with a halogenation agent.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP21080587A JPS6456681A (en) | 1987-08-25 | 1987-08-25 | Novel macrolide compound |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP21080587A JPS6456681A (en) | 1987-08-25 | 1987-08-25 | Novel macrolide compound |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6456681A true JPS6456681A (en) | 1989-03-03 |
Family
ID=16595426
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP21080587A Pending JPS6456681A (en) | 1987-08-25 | 1987-08-25 | Novel macrolide compound |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6456681A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5177063A (en) * | 1991-03-11 | 1993-01-05 | Merck & Co., Inc. | Avermectin compounds with a 6,5-spiroketal ring system |
JPH0597859A (en) * | 1991-10-04 | 1993-04-20 | Sankyo Co Ltd | 15-hydroxymilbemycin derivative and its production |
-
1987
- 1987-08-25 JP JP21080587A patent/JPS6456681A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5177063A (en) * | 1991-03-11 | 1993-01-05 | Merck & Co., Inc. | Avermectin compounds with a 6,5-spiroketal ring system |
JPH0597859A (en) * | 1991-10-04 | 1993-04-20 | Sankyo Co Ltd | 15-hydroxymilbemycin derivative and its production |
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