JPS6447719A - Hyperlipemia alleviating drug - Google Patents

Hyperlipemia alleviating drug

Info

Publication number
JPS6447719A
JPS6447719A JP62204904A JP20490487A JPS6447719A JP S6447719 A JPS6447719 A JP S6447719A JP 62204904 A JP62204904 A JP 62204904A JP 20490487 A JP20490487 A JP 20490487A JP S6447719 A JPS6447719 A JP S6447719A
Authority
JP
Japan
Prior art keywords
earthworm
hyperlipemia
dried powder
give
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP62204904A
Other languages
Japanese (ja)
Other versions
JPH0780777B2 (en
Inventor
Yoichi Ishii
Hisashi Mihara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIMEI KK
Eimei Co Ltd
Original Assignee
EIMEI KK
Eimei Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EIMEI KK, Eimei Co Ltd filed Critical EIMEI KK
Priority to JP62204904A priority Critical patent/JPH0780777B2/en
Priority to KR1019880007133A priority patent/KR930001983B1/en
Priority to KR1019880007131A priority patent/KR930002009B1/en
Priority to US07/228,672 priority patent/US5024844A/en
Priority to DE3827623A priority patent/DE3827623C2/en
Priority to GB8819523A priority patent/GB2208602B/en
Priority to CA000575021A priority patent/CA1322956C/en
Priority to CN88106168A priority patent/CN1031653A/en
Publication of JPS6447719A publication Critical patent/JPS6447719A/en
Priority to US07/641,519 priority patent/US5128148A/en
Publication of JPH0780777B2 publication Critical patent/JPH0780777B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals

Abstract

PURPOSE:To obtain a hyperlipemia alleviating drug having excellent alleviating activity against hyperlipemia, comprising dried powder or an extract of earthworm as an active ingredient. CONSTITUTION:Castings in digestive tube of live earthworm are vomited, dirt attached to the earthworm is washed with water, removed or the above- mentioned operations are carried out in the reverse order. The earthworm is ground in a wet state to give a suspension, which is frozen at -10--60 deg.C. Then freezing and vacuum drying are carried out in a temperature range of -60-80 deg.C at <=10mmHg degree of vacuum for 10-100hr while stepwise raising temperature and the final process of the freezing and vacuum drying is done at 70-80 deg.C for 0.01-0.5mmHg for 5-10hr to give dried powder of earthworm. The suspension or the dried powder in the operation is extracted with an extractant selected from an aqueous solvent, a water-miscible solvent or a water- immiscible organic solvent and the extracting solvent is removed to give an extract. A hyperlipemia alleviating drug contains the dried powder or the extract obtained by the operation.
JP62204904A 1987-08-18 1987-08-18 Antihyperlipidemic agent Expired - Lifetime JPH0780777B2 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
JP62204904A JPH0780777B2 (en) 1987-08-18 1987-08-18 Antihyperlipidemic agent
KR1019880007133A KR930001983B1 (en) 1987-08-18 1988-06-14 Process for the production of dried earthworm powder
KR1019880007131A KR930002009B1 (en) 1987-08-18 1988-06-14 Antihyperlipemics
US07/228,672 US5024844A (en) 1987-08-18 1988-08-05 Process for the production of dried earthworm powder and antihyperlipemic, antidiabetic, antihypertensive and antihypotensive preparations containing dried earthworm powder as active ingredient
DE3827623A DE3827623C2 (en) 1987-08-18 1988-08-15 Process for the preparation of pharmaceutically usable dried earthworm powder and its use as an antihyperlipemic, anti-diabetic, antihypertensive and antihypotonic preparation
GB8819523A GB2208602B (en) 1987-08-18 1988-08-17 Process for the production of dried earthworm powder and antihyperlipemic,anti-diabetic,antihypertensive and antihypotensive preparations containing dried ear
CA000575021A CA1322956C (en) 1987-08-18 1988-08-17 Process for the production of dried earthworm powder and antihyperlipemic, antidiabetic, antihypertensive and antihypotensive preparations containing dried earthworm powder as active ingredient
CN88106168A CN1031653A (en) 1987-08-18 1988-08-18 Dry earthworm powder and contain the hyperlipidemia of dry earthworm powder as active component, anti-diabetic, the production method of the preparation of resisting hypertension and hypotension
US07/641,519 US5128148A (en) 1987-08-18 1991-01-15 Process for the production of dried earthworm powder and antihyperlipemic, antidiabetic, antihypertensive and antihypotensive preparations containing dried earthworm powder as active ingredient

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62204904A JPH0780777B2 (en) 1987-08-18 1987-08-18 Antihyperlipidemic agent

Publications (2)

Publication Number Publication Date
JPS6447719A true JPS6447719A (en) 1989-02-22
JPH0780777B2 JPH0780777B2 (en) 1995-08-30

Family

ID=16498314

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62204904A Expired - Lifetime JPH0780777B2 (en) 1987-08-18 1987-08-18 Antihyperlipidemic agent

Country Status (2)

Country Link
JP (1) JPH0780777B2 (en)
KR (1) KR930002009B1 (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008081476A (en) * 2006-09-29 2008-04-10 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 Method for producing dried powder of earthworm
EP2105139A1 (en) 2008-03-26 2009-09-30 Well Stone Co. Method of producing a dry earthworm powder
EP2316464A1 (en) 2009-10-13 2011-05-04 Well Stone Co. Method of producing a dry earthworm powder
US8137701B2 (en) 2008-03-21 2012-03-20 Well Stone Co. Method of producing a dry earthworm powder
WO2012073593A1 (en) 2011-04-11 2012-06-07 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 Manufacturing method for dried earthworm powder
WO2018173972A1 (en) 2017-03-21 2018-09-27 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 Method for producing therapeutic agent for skin lesions, and therapeutic agent for skin lesions
WO2018173971A1 (en) 2017-03-21 2018-09-27 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 Production method of nasal drop composition, and nasal drop composition

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101884939B1 (en) * 2016-10-24 2018-08-03 안동대학교 산학협력단 Composition containing Lumbricus rubellus extract reducing lipid accumulation as effective component

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008081476A (en) * 2006-09-29 2008-04-10 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 Method for producing dried powder of earthworm
US8137701B2 (en) 2008-03-21 2012-03-20 Well Stone Co. Method of producing a dry earthworm powder
EP2105139A1 (en) 2008-03-26 2009-09-30 Well Stone Co. Method of producing a dry earthworm powder
EP2316464A1 (en) 2009-10-13 2011-05-04 Well Stone Co. Method of producing a dry earthworm powder
US8394417B2 (en) 2009-10-13 2013-03-12 Well Stone Co. Method of producing a dry earthworm powder
WO2012073593A1 (en) 2011-04-11 2012-06-07 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 Manufacturing method for dried earthworm powder
US9511098B2 (en) 2011-04-11 2016-12-06 Well Stone Co. Method for producing dry earthworm powder
WO2018173972A1 (en) 2017-03-21 2018-09-27 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 Method for producing therapeutic agent for skin lesions, and therapeutic agent for skin lesions
WO2018173971A1 (en) 2017-03-21 2018-09-27 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 Production method of nasal drop composition, and nasal drop composition

Also Published As

Publication number Publication date
KR890003394A (en) 1989-04-14
KR930002009B1 (en) 1993-03-20
JPH0780777B2 (en) 1995-08-30

Similar Documents

Publication Publication Date Title
JPS6447718A (en) Diabetic remedy
JPS6447719A (en) Hyperlipemia alleviating drug
RU2003100095A (en) THE IMPROVED METHOD FOR EXTRACTION OF CACAO PROZYANIDINES
AU1564692A (en) Process for producing a storable azadirachtin-rich insecticide from sperm nuclei of the neem tree
US4254112A (en) Inula extract, its method of preparation and its use as pharmaceutical
JPS6447720A (en) Production of dried powder of earthworm
JPS5562004A (en) Control agent against plant viral disease
AU534573B2 (en) Decaffeinated coffee blend
RU96105244A (en) METHOD FOR PRODUCING LAPAPACONITINE HYDROBROMIDE
RU97105437A (en) METHOD FOR PRODUCING BIOLOGICALLY ACTIVE Triterpene Acids
Hong et al. A study on the infection status of tadpoles and frogs by the metacercariae of Fibricola seoulensis in Korea
JPS5550859A (en) Purification of lecithin
FR2439553A1 (en) GROSS PROCESS
JPS5452790A (en) Preparation of coenzyme q
Rush Vol. 57, No. 9--PLANT DISEASE REPORTER--September 1973 715 LEAF SCALD OF RICE OBSERVED IN LOUISIANA
Kang et al. Appearance of striga, a phanerogamic parasite, on sugarcane in Morinda Mill area of Punjab.
Ikawa et al. Chemical and physiological studies on the marine dinoflagellate Amphidinium carterae.
SU134388A1 (en) Nephrolitic Drug
RU97105728A (en) METHOD FOR PRODUCING ESTROGENIC ACTIVITY PRODUCT
CN105832813A (en) Method for purifying puerarin in Heshui radix pueraria thomsonii
SU727199A1 (en) Ononine producing method
JPS5655334A (en) Dimeric tetrahydroanthracene compound
Rao Vascular wilts of cotton.
RU99123176A (en) METHOD FOR PRODUCING MEANS FOR INCREASING SEX ACTIVITY AND REPRODUCTIVE FUNCTION IN MEN
IE792249L (en) Proces for the preparation of 2,3-dihydro-2,2-dimethyl-¹7-hydroxybenzofuran

Legal Events

Date Code Title Description
R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

EXPY Cancellation because of completion of term