JPS6443758A - Amplified detection of biocomponent - Google Patents
Amplified detection of biocomponentInfo
- Publication number
- JPS6443758A JPS6443758A JP20004287A JP20004287A JPS6443758A JP S6443758 A JPS6443758 A JP S6443758A JP 20004287 A JP20004287 A JP 20004287A JP 20004287 A JP20004287 A JP 20004287A JP S6443758 A JPS6443758 A JP S6443758A
- Authority
- JP
- Japan
- Prior art keywords
- iii
- change
- layers
- reaction
- light interference
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
PURPOSE:To improve sensitivity by bringing a material which can react specifically with another reaction section in a detecting material while bringing the detecting material into reaction with a material to be detected and amplifying the change in the light interference color or the change in the various densities of a device surface. CONSTITUTION:A light interference II layer is formed on a light reflecting substrate I such as metallic sheet to constitute the device. A reactive intermediate layer consisting of a compd. which reacts with antigens or antibodies is provided between the layers of the antigen material or antibody protein layer III on the device to fix the layers III. The layers III are the antigen material of the material to be detected in the specimen or the antibody protein. The material IV for detection is added to the specimen liquid and is brought into reaction competitively with the materials III in the specimen liquid and on the device surface and the specific reaction with the material IV is effected by the material V such as high-polymer compd. in the section different from the layers III. The change in the light interference color or the change in the various densities of the reflected light is amplified.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP20004287A JPS6443758A (en) | 1987-08-12 | 1987-08-12 | Amplified detection of biocomponent |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP20004287A JPS6443758A (en) | 1987-08-12 | 1987-08-12 | Amplified detection of biocomponent |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6443758A true JPS6443758A (en) | 1989-02-16 |
Family
ID=16417862
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP20004287A Pending JPS6443758A (en) | 1987-08-12 | 1987-08-12 | Amplified detection of biocomponent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6443758A (en) |
-
1987
- 1987-08-12 JP JP20004287A patent/JPS6443758A/en active Pending
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